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lef-2
Euk-VirHyposidra_talaca_nucleopolyhedrovirus
lef-2__YP_010086382__Hyposidra_talaca_nucleopolyhedrovirus__1070315
Identity
- Accession:
- YP_010086382 ↗
- Protein ID:
- lef-2
- Kingdom:
- euk
Quality
78.9
mean pLDDT
Taxonomy
TaxID: 1070315
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 12-67
Domain cluster:
rep: lef2__YP_009666652__Oxyplax_ochracea_nucleopolyhedrovirus__2083176__D13-67
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03041.21 best | Baculo_LEF-2 | 42.4 | 9.60e-11 | 80.4% | 27.7% |
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6p3qA02 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.63 | 50.0 | 3.67e-01 | 89.3% | 89.9% |
| 4y4mC00 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.62 | 50.0 | 3.34e-01 | 94.6% | 31.4% |
| 2gzoA02 | 3.30.70.1300 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › VC0467-like domains | 0.61 | 47.0 | 4.06e-01 | 85.7% | 57.3% |
| 2e9xB01 | 3.40.5.50 | Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › | 0.61 | 44.0 | 4.22e-01 | 78.6% | 71.2% |
| 4ne4A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.58 | 44.0 | 3.25e-01 | 85.7% | 64.7% |
| 2v5tA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.58 | 45.0 | 3.94e-01 | 91.1% | 88.3% |
| 4k22B01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 46.0 | 3.05e-01 | 91.1% | 31.8% |
| 2fwrA01 | 3.40.1170.30 | Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › | 0.56 | 39.0 | 3.94e-01 | 98.2% | 73.7% |
| 4cbpB02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 45.0 | 3.79e-01 | 92.9% | 78.8% |
| 2iepA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 45.0 | 3.94e-01 | 96.4% | 65.6% |
| 1o9gA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 46.0 | 3.25e-01 | 100.0% | 38.3% |
| 1pdaA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 41.0 | 3.38e-01 | 82.1% | 82.6% |
| 1fxkC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 47.0 | 3.52e-01 | 92.9% | 50.4% |
| 5bxyA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.55 | 46.0 | 3.44e-01 | 98.2% | 40.9% |
| 6c62A00 | 3.90.1300.10 | Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain | 0.55 | 45.0 | 2.75e-01 | 100.0% | 77.7% |
| 1yj7B01 | 3.30.70.1530 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 | 0.54 | 37.0 | 3.49e-01 | 71.4% | 76.1% |
| 5yxkA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 43.0 | 3.59e-01 | 92.9% | 74.5% |
| 3p3yA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 41.0 | 3.51e-01 | 89.3% | 81.1% |
| 3kvqA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 41.0 | 3.82e-01 | 92.9% | 90.2% |
| 2vraA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 42.0 | 3.62e-01 | 92.9% | 89.1% |
| 1ji6A02 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.53 | 39.0 | 2.92e-01 | 82.1% | 95.7% |
| 2mkyA00 | 3.30.70.1530 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 | 0.53 | 36.0 | 3.65e-01 | 73.2% | 100.0% |
| 2a5yC03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 41.0 | 3.34e-01 | 85.7% | 64.0% |
| 2zdiC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 43.0 | 3.24e-01 | 92.9% | 45.9% |
| 1u2hA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 42.0 | 3.69e-01 | 94.6% | 67.7% |
| 7xoiD01 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.53 | 40.0 | 3.35e-01 | 85.7% | 82.2% |
| 5e7gA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 43.0 | 3.86e-01 | 96.4% | 94.0% |
| 2hrvA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.52 | 36.0 | 3.86e-01 | 83.9% | 95.5% |
| 2cw7A02 | 1.10.10.1010 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Intein homing endonuclease, domain IV | 0.52 | 39.0 | 3.05e-01 | 87.5% | 82.9% |
| 4u7mA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 40.0 | 3.58e-01 | 92.9% | 86.2% |
| 8begA03 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 42.0 | 3.24e-01 | 98.2% | 95.3% |
| 2fpoC00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 40.0 | 2.94e-01 | 91.1% | 38.1% |
| 3r8yA01 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.51 | 36.0 | 3.49e-01 | 76.8% | 69.7% |
| 2iewB00 | 3.30.470.160 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Inositol polyphosphate kinase | 0.51 | 41.0 | 2.79e-01 | 96.4% | 77.3% |
| 3mydA01 | 3.40.30.60 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › FHIPEP family, domain 1 | 0.51 | 39.0 | 3.01e-01 | 87.5% | 46.5% |
| 1cc8A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 36.0 | 3.37e-01 | 76.8% | 81.9% |
| 2qpwA01 | 2.170.270.10 | Mainly Beta › Beta Complex › Beta-clip-like › SET domain | 0.51 | 38.0 | 3.10e-01 | 89.3% | 88.1% |
| 3orjA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 42.0 | 3.77e-01 | 98.2% | 87.1% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3402914 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.84 | 60.0 | 5.28e-01 | 75.0% | 57.0% |
| 4088754 | 2003.1.2.19 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Thi4 | 0.62 | 50.0 | 3.26e-01 | 92.9% | 28.9% |
| 3578515 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.59 | 46.0 | 3.96e-01 | 89.3% | 87.4% |
| 3793483 | 11.1.1.179 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 | 0.58 | 47.0 | 4.06e-01 | 94.6% | 88.4% |
| 2702266 | 2003.1.2.21 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Trp_halogenase | 0.58 | 45.0 | 2.98e-01 | 89.3% | 67.1% |
| 3729291 | 108.1.1.1 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1 | 0.57 | 44.0 | 3.65e-01 | 87.5% | 79.0% |
| 4089702 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 43.0 | 3.75e-01 | 92.9% | 67.6% |
| None | — | 0.57 | 42.0 | 3.01e-01 | 83.9% | 29.5% | |
| None | — | 0.56 | 46.0 | 3.34e-01 | 98.2% | 33.5% | |
| 3996108 | 11.1.1.179 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 | 0.56 | 44.0 | 3.84e-01 | 92.9% | 87.4% |
| 3887983 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 43.0 | 3.52e-01 | 91.1% | 72.5% |
| 3501847 | 11.1.1.179 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 | 0.56 | 43.0 | 3.76e-01 | 91.1% | 90.5% |
| 3497317 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.56 | 44.0 | 4.09e-01 | 91.1% | 100.0% |
| 3994347 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.55 | 43.0 | 3.75e-01 | 91.1% | 86.3% |
| 3847528 | 2003.1.5.209 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF29244 | 0.55 | 45.0 | 3.16e-01 | 98.2% | 29.8% |
| 3741050 | 2007.1.16.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn | 0.55 | 38.0 | 3.13e-01 | 78.6% | 44.0% |
| 3549800 | 11.1.1.178 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_2 | 0.55 | 43.0 | 3.63e-01 | 89.3% | 91.0% |
| 3923524 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.54 | 45.0 | 3.86e-01 | 96.4% | 87.4% |
| 3914199 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 41.0 | 3.46e-01 | 89.3% | 78.2% |
| 2996557 | 11.1.1.179 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 | 0.54 | 41.0 | 3.53e-01 | 89.3% | 86.0% |
| 3774968 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.53 | 41.0 | 3.42e-01 | 91.1% | 75.7% |
| 4940994 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.53 | 40.0 | 3.32e-01 | 83.9% | 79.0% |
| 3922724 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 42.0 | 3.62e-01 | 94.6% | 63.0% |
| 2441993 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.53 | 42.0 | 3.72e-01 | 96.4% | 68.4% |
| 4459447 | 4178.1.1.0 ↗ | beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain | 0.53 | 42.0 | 3.37e-01 | 94.6% | 80.8% |
| 3566417 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 42.0 | 2.86e-01 | 96.4% | 32.4% |
| 3503603 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.52 | 40.0 | 3.53e-01 | 91.1% | 85.3% |
| 4397567 | 601.23.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III | 0.52 | 38.0 | 2.46e-01 | 80.4% | 19.6% |
| 3290028 | 7523.1.1.15 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate | 0.52 | 40.0 | 3.25e-01 | 85.7% | 70.0% |
| 4185652 | 601.23.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III | 0.52 | 38.0 | 2.43e-01 | 78.6% | 19.6% |
| 3937771 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.52 | 43.0 | 3.03e-01 | 100.0% | 96.2% |
| 4433461 | 601.23.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III | 0.51 | 39.0 | 2.51e-01 | 83.9% | 19.3% |
| 3278051 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.51 | 37.0 | 2.64e-01 | 82.1% | 85.4% |
| 3900677 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 40.0 | 3.18e-01 | 94.6% | 63.7% |
| 5050923 | 2003.1.5.16 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CheR | 0.50 | 38.0 | 2.52e-01 | 85.7% | 23.8% |
| 3251739 | 11.1.5.62 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › CBM49 | 0.50 | 38.0 | 3.23e-01 | 87.5% | 93.3% |
| 4936467 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.50 | 38.0 | 2.87e-01 | 87.5% | 90.0% |
| 5045645 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.50 | 39.0 | 2.89e-01 | 92.9% | 96.1% |
D2
high
residues 100-211
Domain cluster:
rep: LEF-2__YP_009552671__Operophtera_brumata_nucleopolyhedrovirus__1046267__D88-194
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03041.21 best | Baculo_LEF-2 | 106.9 | 1.30e-30 | 71.4% | 49.7% |