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lef-4

Euk-Vir

Agrotis_segetum_nucleopolyhedrovirus_B

lef-4__YP_009112642__Agrotis_segetum_nucleopolyhedrovirus_B__1580580

Identity

Accession:
YP_009112642 ↗
Protein ID:
lef-4
Kingdom:
euk

Quality

81.0 mean pLDDT

Taxonomy

Naldaviricetes› Lefavirales› Baculoviridae› Alphabaculovirus› Agrotis_segetum_nucleopolyhedrovirus_B

TaxID: 1580580

Cluster

View cluster (54 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 13-45_94-204
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 134.6 7.40e-39 77.8% 23.7%
PF05098.19 LEF-4 37.6 2.00e-09 23.6% 7.4%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1swgC00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.69 35.0 3.80e-01 72.2% 55.6%
2lmeA00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.69 29.0 3.35e-01 72.2% 51.4%
4h5bA00 3.30.1460.70 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.61 33.0 3.31e-01 99.3% 48.7%
1of5B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 37.0 3.91e-01 88.2% 68.0%
2hzmB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.59 54.0 4.59e-01 98.6% 85.5%
2joxA00 2.60.40.4240 Mainly Beta › Sandwich › Immunoglobulin-like › Transcription activator, Churchill 0.56 33.0 3.75e-01 95.1% 78.3%
2qiyA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 33.0 3.40e-01 78.5% 61.9%
5azpA02 2.20.200.10 Mainly Beta › Single Sheet › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.54 31.0 3.93e-01 70.1% 98.8%
3kulA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 27.0 3.27e-01 98.6% 74.2%
3q0xA01 2.170.210.20 Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › Spindle assembly abnormal protein 6, N-terminal domain 0.53 38.0 3.73e-01 73.6% 85.8%
5a67A00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.51 46.0 4.08e-01 97.9% 86.4%
2h36X00 3.30.160.300 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.50 32.0 3.60e-01 75.7% 84.3%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1018790 9.2.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Avidin 0.69 36.0 3.75e-01 73.6% 54.2%
4030906 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.62 34.0 3.59e-01 77.1% 59.2%
4059717 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.59 31.0 3.80e-01 86.1% 81.2%
4019099 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.56 35.0 3.61e-01 87.5% 64.4%
3233373 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.56 45.0 4.14e-01 84.0% 99.4%
3960152 241.1.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.55 33.0 3.39e-01 100.0% 60.7%
3741473 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.55 32.0 3.39e-01 92.4% 64.0%
4939185 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 36.0 3.85e-01 95.1% 80.8%
3330582 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 36.0 3.79e-01 95.8% 79.2%
3433055 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.51 36.0 3.77e-01 88.2% 77.8%
3620794 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.51 45.0 4.45e-01 94.4% 98.7%
D2 high residues 212-412
PDB
Domain cluster: rep: late_expression_factor_4__YP_667910__Neodiprion_abietis_NPV__204507__D219-367
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 250.8 4.20e-74 100.0% 40.0%
D3 high residues 416-471
PDB
Domain cluster: rep: lef4__YP_002854687__Euproctis_pseudoconspersa_nucleopolyhedrovirus__307467__D411-465
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 40.8 2.10e-10 100.0% 11.4%
D4 medium residues 1-12_46-93
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 36.7 3.70e-09 93.3% 10.3%
CATH (82)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ptfA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 59.0 4.39e-01 93.3% 89.1%
2h2qB01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.67 56.0 3.79e-01 91.7% 26.9%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.65 54.0 4.08e-01 93.3% 41.4%
4hudA01 3.30.2000.40 Alpha Beta › 2-Layer Sandwich › STM4215-like › Myoviridae tail sheath stabiliser 0.64 57.0 3.90e-01 100.0% 48.1%
2wzpP01 2.40.30.210 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.64 53.0 4.44e-01 95.0% 69.7%
2bkyX00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.64 53.0 4.73e-01 91.7% 69.8%
4dzdA02 3.30.70.1210 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 0.64 54.0 4.26e-01 93.3% 72.4%
3sm3A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 55.0 3.69e-01 93.3% 45.8%
1vm0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.63 56.0 4.83e-01 98.3% 72.0%
3a27A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 53.0 3.58e-01 93.3% 28.3%
2rjzA02 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.62 53.0 4.46e-01 95.0% 56.6%
1vwxP00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.62 51.0 3.86e-01 95.0% 92.8%
4f0qD01 2.30.280.20 Mainly Beta › Roll › PUA domain-like › 0.62 53.0 3.57e-01 100.0% 45.1%
2j5aA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.62 52.0 4.26e-01 91.7% 66.0%
4bsjA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 51.0 4.07e-01 93.3% 64.2%
3qkbA00 3.30.110.70 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Hypothetical protein apc22750. Chain B 0.61 51.0 4.47e-01 95.0% 83.0%
1vs3A02 3.30.70.660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Pseudouridine synthase I, catalytic domain, C-terminal subdomain 0.61 47.0 3.65e-01 86.7% 61.1%
3zfvA02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 50.0 3.80e-01 95.0% 68.6%
2cc6A00 3.30.1660.10 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin 0.61 51.0 5.03e-01 93.3% 93.8%
3bczA00 3.40.830.10 Alpha Beta › 3-Layer(aba) Sandwich › Protocatechuate 4,5-dioxygenase; Chain B › LigB-like 0.60 50.0 3.24e-01 93.3% 87.7%
6h05A00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.60 50.0 3.36e-01 93.3% 77.1%
1y7pB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.60 51.0 4.65e-01 93.3% 70.0%
3rt0C00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.60 50.0 3.67e-01 95.0% 70.3%
2yqzA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 49.0 3.47e-01 91.7% 31.1%
2ichA01 2.40.370.10 Mainly Beta › Beta Barrel › AttH-like fold › AttH-like domain 0.60 48.0 3.55e-01 93.3% 75.4%
2vxaA00 3.30.1660.10 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin 0.60 50.0 4.93e-01 93.3% 90.9%
2bi0A02 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.60 46.0 3.48e-01 83.3% 88.4%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.60 49.0 3.60e-01 90.0% 34.4%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.59 50.0 3.58e-01 91.7% 33.7%
5ejlA02 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.59 48.0 3.89e-01 93.3% 56.5%
4noiA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.59 48.0 4.05e-01 91.7% 64.1%
3kp0A03 3.30.30.60 Alpha Beta › 2-Layer Sandwich › Defensin A-like › D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain 0.59 51.0 4.91e-01 95.0% 83.6%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.59 48.0 4.01e-01 91.7% 61.3%
5uejA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.04e-01 95.0% 72.8%
3pfoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 3.89e-01 95.0% 70.3%
2v8hA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 49.0 3.99e-01 95.0% 67.2%
3n5fA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.02e-01 95.0% 69.3%
4c98A02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 47.0 3.74e-01 96.7% 69.3%
3l60A01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.57 48.0 3.29e-01 95.0% 80.0%
3qjlA02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 3.86e-01 93.3% 76.5%
2gjvA00 3.30.2000.10 Alpha Beta › 2-Layer Sandwich › STM4215-like › Phage tail protein-like 0.57 46.0 3.60e-01 91.7% 50.7%
5k8mA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 47.0 3.71e-01 93.3% 73.3%
4za1C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 4.14e-01 91.7% 66.3%
6y1zA01 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.57 45.0 3.21e-01 93.3% 35.8%
1d5aA01 3.30.342.10 Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 0.56 43.0 3.36e-01 88.3% 52.3%
1vmbA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.56 46.0 3.89e-01 93.3% 63.6%
2bj0A00 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.56 47.0 3.29e-01 95.0% 41.9%
2w8eA00 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.56 45.0 3.19e-01 93.3% 35.5%
2f7vA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 48.0 3.94e-01 95.0% 73.1%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.55 45.0 3.84e-01 90.0% 74.0%
4aeeA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 40.0 3.44e-01 91.7% 47.4%
4ozjA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 46.0 3.86e-01 91.7% 56.7%
2nyiA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.55 43.0 3.92e-01 93.3% 64.4%
6wubf01 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.55 45.0 3.94e-01 93.3% 71.3%
3maeA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.54 42.0 2.97e-01 91.7% 74.8%
3lvtA03 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 45.0 3.65e-01 98.3% 72.1%
1dpbA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.54 42.0 2.96e-01 93.3% 72.4%
2wmfA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.54 41.0 3.25e-01 93.3% 39.7%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.54 44.0 3.07e-01 93.3% 27.4%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 44.0 3.75e-01 95.0% 99.0%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 44.0 3.82e-01 96.7% 100.0%
3tx8A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 46.0 3.71e-01 95.0% 72.8%
1tz0B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 43.0 3.72e-01 90.0% 64.9%
4y6iA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 43.0 3.74e-01 95.0% 100.0%
1vq8R00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.53 44.0 3.43e-01 96.7% 88.7%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.53 41.0 3.75e-01 91.7% 71.1%
4afhE00 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.53 43.0 3.06e-01 95.0% 42.5%
2nuhA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 44.0 3.75e-01 96.7% 99.0%
3o3uN03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 44.0 3.68e-01 96.7% 62.2%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 43.0 3.87e-01 93.3% 64.0%
2pokA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 42.0 3.17e-01 95.0% 78.8%
4v19W00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.52 41.0 3.18e-01 96.7% 63.3%
1cwvA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 3.66e-01 95.0% 55.9%
2wyhA05 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 2.98e-01 80.0% 82.8%
3jafA01 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.52 40.0 2.91e-01 93.3% 34.6%
6zzmA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.51 39.0 2.80e-01 91.7% 78.9%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 45.0 3.77e-01 98.3% 97.0%
4iyqA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 40.0 3.53e-01 96.7% 96.3%
2p8jA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 41.0 2.96e-01 96.7% 42.2%
2w2sA00 3.10.460.20 Alpha Beta › Roll › VSV matrix protein › Rhabdovirus matrix protein M2 0.51 42.0 3.14e-01 95.0% 70.6%
4ewtA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 40.0 3.39e-01 95.0% 67.8%
2x1wL02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 41.0 3.55e-01 98.3% 61.9%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4118093 1.1.5.17 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.75 64.0 4.69e-01 93.3% 85.8%
3719492 304.102.1.1 ↗ a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_2 0.73 60.0 3.80e-01 91.7% 36.7%
2892215 5091.1.1.1 ↗ beta sandwiches › VP4 membrane interaction domain › VP4 membrane interaction domain › VP4 membrane interaction domain › Rota_VP4_MID 0.71 60.0 4.04e-01 96.7% 38.3%
3623538 873.1.1.5 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB 0.70 58.0 4.17e-01 93.3% 36.7%
3603456 304.8.1.82 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › PF27325 0.69 59.0 5.13e-01 93.3% 70.0%
4966859 304.51.1.8 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6b_C 0.68 47.0 4.38e-01 71.7% 60.0%
3687709 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.67 59.0 3.85e-01 93.3% 33.3%
4955179 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.67 55.0 4.35e-01 93.3% 71.5%
3972051 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 56.0 4.38e-01 95.0% 47.7%
3974775 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.66 57.0 4.88e-01 95.0% 61.1%
4029744 304.112.1.0 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.65 58.0 4.39e-01 100.0% 71.7%
3943282 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.65 54.0 4.35e-01 93.3% 58.3%
5053266 1.1.5.17 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.65 52.0 3.88e-01 90.0% 68.1%
3684280 310.3.1.14 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › DUF7049 0.65 54.0 5.44e-01 90.0% 100.0%
4309280 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.65 53.0 4.18e-01 95.0% 67.4%
4927441 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.64 50.0 4.51e-01 90.0% 78.9%
3596783 328.1.1.0 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like 0.64 57.0 4.55e-01 98.3% 60.0%
3667432 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 56.0 4.73e-01 95.0% 64.2%
4025055 328.1.1.1 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like › Alba 0.64 54.0 4.62e-01 93.3% 66.3%
3665392 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 55.0 4.34e-01 95.0% 49.2%
4944896 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.64 52.0 4.17e-01 95.0% 73.4%
4946915 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 52.0 4.32e-01 93.3% 51.4%
3540649 11.1.1.789 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › KIAA1549 0.63 53.0 4.23e-01 93.3% 65.0%
5036750 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.63 52.0 4.03e-01 95.0% 67.9%
3355267 872.1.1.0 ↗ a+b two layers › Dodecin subunit-like › Flavin-binding protein dodecin-like › Flavin-binding protein dodecin-like 0.63 53.0 4.80e-01 93.3% 93.8%
5072924 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.62 54.0 4.13e-01 95.0% 72.6%
3766159 309.1.2.1 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › tRNA_SAD 0.62 51.0 3.67e-01 95.0% 83.6%
5052888 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.62 52.0 4.23e-01 100.0% 73.6%
3972057 11.1.1.410 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › BatD 0.61 51.0 4.29e-01 95.0% 57.1%
3956950 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.61 50.0 3.90e-01 95.0% 64.3%
4953567 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.61 51.0 4.64e-01 93.3% 71.2%
4946264 323.1.1.1 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.61 51.0 3.37e-01 95.0% 81.5%
5024188 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.60 53.0 4.20e-01 95.0% 69.6%
3764712 11.1.1.118 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Adhes-Ig_like 0.60 50.0 3.95e-01 95.0% 51.5%
3970088 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 51.0 4.36e-01 93.3% 64.2%
3776086 306.10.1.5 ↗ a+b two layers › Glucose permease domain IIB-like › H1 domain of KCTD12 › H1 domain of KCTD12 › PF31088 0.60 50.0 3.89e-01 91.7% 89.2%
3995786 389.4.1.7 ↗ few secondary structure elements › EGF-like › Fibulin-4 EGF-like 1 domain › Fibulin-4 EGF-like 1 domain › TIL_2 0.60 51.0 5.05e-01 96.7% 100.0%
4938014 218.2.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.60 50.0 3.97e-01 96.7% 96.3%
3387365 872.8.1.0 ↗ a+b two layers › Dodecin subunit-like › Probable RNA-binding protein N-terminal domain › Probable RNA-binding protein N-terminal domain 0.60 51.0 4.97e-01 93.3% 86.2%
3802659 304.8.1.66 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF7049 0.60 49.0 4.18e-01 95.0% 61.0%
4973645 11.1.1.130 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Inhibitor_I42 0.60 51.0 4.45e-01 95.0% 66.7%
4974938 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.60 49.0 3.43e-01 93.3% 38.8%
3418881 304.8.1.66 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF7049 0.59 50.0 4.11e-01 93.3% 61.8%
4943905 323.1.1.1 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.59 49.0 3.26e-01 95.0% 79.2%
5077058 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.59 47.0 3.79e-01 90.0% 72.8%
5077618 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.59 48.0 3.85e-01 91.7% 73.6%
4928518 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.58 49.0 3.43e-01 95.0% 45.6%
5070955 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.58 46.0 3.71e-01 95.0% 73.6%
901 4252.1.1.1 ↗ beta barrels › AttH-like › AttH-like › AttH-like › CrtC 0.58 47.0 3.42e-01 95.0% 74.6%
3279365 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 46.0 3.17e-01 90.0% 34.4%
3602774 304.51.1.8 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6b_C 0.57 46.0 3.84e-01 93.3% 73.0%
3883286 11.1.1.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.57 48.0 3.80e-01 93.3% 44.8%
4286263 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.57 48.0 3.73e-01 93.3% 73.8%
4958007 11.1.1.130 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Inhibitor_I42 0.57 48.0 4.16e-01 98.3% 62.0%
3839035 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.57 46.0 3.42e-01 91.7% 35.0%
5024124 304.15.1.0 ↗ a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.57 47.0 4.30e-01 93.3% 72.5%
4928530 328.1.1.0 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like 0.56 43.0 4.03e-01 90.0% 75.0%
4940026 4081.1.1.17 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › DUF7345 0.56 45.0 3.37e-01 93.3% 51.4%
3898132 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.55 45.0 3.57e-01 96.7% 74.3%
4659258 2003.1.5.51 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TPMT 0.55 44.0 3.15e-01 96.7% 32.1%
3992575 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.55 44.0 3.34e-01 95.0% 45.5%
3589403 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.54 42.0 3.48e-01 90.0% 50.8%
1312442 12.1.1.43 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Glyco_hydro_38 0.54 45.0 3.76e-01 98.3% 80.2%
4928521 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.54 44.0 3.08e-01 93.3% 68.3%
4124706 76.1.1.1 ↗ beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I › Endotoxin_M 0.54 42.0 3.10e-01 91.7% 98.9%
3194998 4178.1.1.3 ↗ beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › DUF4140 0.54 43.0 3.42e-01 93.3% 41.5%
3883232 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 43.0 3.75e-01 98.3% 57.9%
150358 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.53 43.0 3.06e-01 95.0% 42.5%
327528 328.1.1.2 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like › SpoVS 0.53 41.0 3.75e-01 91.7% 71.1%
3214584 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.53 42.0 2.91e-01 93.3% 31.1%
3552097 11.1.1.242 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › RET_CLD3 0.53 42.0 3.38e-01 93.3% 57.0%
3221989 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.53 41.0 2.98e-01 93.3% 35.2%
4936600 304.51.1.1 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.53 41.0 3.47e-01 93.3% 77.5%
1396465 12.1.1.43 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Glyco_hydro_38 0.52 41.0 3.42e-01 91.7% 70.6%
5052400 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.52 40.0 2.94e-01 93.3% 41.3%
3217135 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.52 41.0 2.93e-01 91.7% 33.7%
3739684 864.1.1.2 ↗ a+b two layers › DLC › DLC › DLC › Tctex-1 0.52 39.0 3.25e-01 83.3% 52.7%
5016732 11.1.1.130 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Inhibitor_I42 0.51 41.0 3.50e-01 95.0% 52.7%
164141 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 41.0 2.96e-01 96.7% 42.2%
4992590 881.2.1.0 ↗ a+b three layers › Mog1p/PsbP-like › TM1622-like › TM1622-like 0.50 41.0 3.08e-01 98.3% 61.1%
4941725 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.50 41.0 3.56e-01 96.7% 100.0%