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mRNA-capping_enzyme
Euk-VirAcanthamoeba_polyphaga_moumouvirus
mRNA-capping_enzyme__YP_007354410__Acanthamoeba_polyphaga_moumouvirus__1269028
Identity
- Accession:
- YP_007354410 ↗
- Protein ID:
- mRNA-capping_enzyme
- Kingdom:
- euk
Quality
71.6
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Moumouvirus›
Acanthamoeba_polyphaga_moumouvirus
TaxID: 1269028
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 239-430
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01331.26 best | mRNA_cap_enzyme | 52.2 | 8.50e-14 | 97.4% | 72.4% |
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ckmA01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.82 | 56.0 | 6.29e-01 | 99.5% | 85.8% |
| 1xk5A01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.79 | 54.0 | 5.39e-01 | 87.5% | 66.8% |
| 4ckbA01 | 3.30.470.140 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › | 0.77 | 52.0 | 5.38e-01 | 100.0% | 72.5% |
| 4pz6A02 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.74 | 67.0 | 6.15e-01 | 100.0% | 75.8% |
| 3rtxA01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.74 | 54.0 | 5.89e-01 | 99.0% | 87.9% |
| 1vs0A02 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.69 | 40.0 | 5.28e-01 | 72.4% | 100.0% |
| 6rarI01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.68 | 51.0 | 5.08e-01 | 76.0% | 87.2% |
| 2hivA02 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.63 | 51.0 | 5.03e-01 | 84.4% | 85.0% |
| 4tquS02 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.60 | 23.0 | 3.75e-01 | 71.4% | 100.0% |
| 3qwuA02 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.57 | 48.0 | 4.96e-01 | 88.5% | 93.3% |
| 1b34B00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.52 | 18.0 | 2.78e-01 | 70.3% | 74.3% |
| 3dsoA00 | 2.40.10.300 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Copper resistance protein K | 0.51 | 20.0 | 3.22e-01 | 71.4% | 100.0% |
| 4oonA03 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.50 | 27.0 | 3.45e-01 | 93.2% | 92.3% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 423186 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.76 | 66.0 | 6.09e-01 | 100.0% | 73.3% |
| 4027847 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.76 | 65.0 | 6.13e-01 | 100.0% | 75.9% |
| 3703188 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.76 | 66.0 | 6.14e-01 | 100.0% | 74.5% |
| 3688782 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.75 | 67.0 | 5.12e-01 | 100.0% | 46.0% |
| 3998394 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.72 | 65.0 | 5.95e-01 | 100.0% | 74.6% |
| 3293200 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.71 | 67.0 | 5.86e-01 | 100.0% | 70.6% |
| 3310146 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.71 | 66.0 | 5.20e-01 | 100.0% | 51.2% |
| 4668736 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.70 | 49.0 | 5.42e-01 | 94.3% | 86.3% |
| 3716788 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.70 | 66.0 | 5.89e-01 | 100.0% | 78.8% |
| 5066075 | 206.1.3.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M | 0.69 | 53.0 | 5.34e-01 | 88.5% | 77.4% |
| 3270724 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.69 | 66.0 | 6.08e-01 | 100.0% | 84.7% |
| 3267830 | 206.1.3.30 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd | 0.68 | 60.0 | 5.40e-01 | 95.8% | 69.6% |
| 3500957 | 206.1.3.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme | 0.68 | 66.0 | 5.90e-01 | 100.0% | 77.2% |
| 3798407 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.67 | 56.0 | 5.36e-01 | 96.4% | 76.3% |
| 3939998 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.66 | 57.0 | 5.12e-01 | 89.6% | 78.4% |
| 3298149 | 206.1.3.30 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd | 0.66 | 59.0 | 5.39e-01 | 97.9% | 73.8% |
| 3288874 | 206.1.3.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M | 0.65 | 52.0 | 5.21e-01 | 81.8% | 80.5% |
| 3397601 | 206.1.3.30 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd | 0.64 | 55.0 | 5.08e-01 | 92.7% | 72.1% |
| 4680450 | 206.1.3.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M | 0.64 | 52.0 | 5.02e-01 | 84.9% | 87.9% |
| 3997608 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.64 | 59.0 | 5.16e-01 | 99.0% | 74.8% |
| 3872907 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.63 | 59.0 | 5.35e-01 | 99.0% | 80.0% |
| 3578637 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.63 | 57.0 | 4.92e-01 | 95.8% | 71.0% |
| 5083927 | 206.1.3.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M | 0.61 | 55.0 | 5.25e-01 | 95.3% | 82.6% |
| 4937749 | 206.1.3.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M | 0.56 | 53.0 | 4.36e-01 | 100.0% | 86.7% |
| 5007422 | 206.1.3.23 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase | 0.56 | 52.0 | 4.76e-01 | 100.0% | 80.8% |
| 5003826 | 206.1.3.23 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase | 0.56 | 52.0 | 4.76e-01 | 100.0% | 80.4% |
| 5012458 | 206.1.3.23 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase | 0.56 | 52.0 | 4.83e-01 | 100.0% | 82.1% |
| 5070559 | 206.1.3.23 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase | 0.56 | 52.0 | 4.79e-01 | 100.0% | 81.2% |
| 1933331 | 2.1.1.78 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PCB_OB | 0.54 | 27.0 | 3.58e-01 | 93.2% | 90.5% |
D2
high
residues 497-638
D3
medium
residues 1-64_209-233
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2j0wA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.57 | 45.0 | 4.48e-01 | 85.4% | 93.5% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 30.0 | 2.82e-01 | 87.6% | 41.1% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3412102 | 109.54.1.7 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Nol11_C | 0.57 | 37.0 | 3.36e-01 | 82.0% | 49.2% |
| 3743916 | 109.3.1.96 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 | 0.56 | 30.0 | 2.44e-01 | 80.9% | 27.6% |
| 3513384 | 109.4.1.263 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N | 0.55 | 28.0 | 2.58e-01 | 80.9% | 36.7% |
| 4940643 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.53 | 37.0 | 2.83e-01 | 73.0% | 68.9% |
| 3925326 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.52 | 31.0 | 2.51e-01 | 77.5% | 30.6% |
| 4428399 | 632.11.1.10 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA | 0.51 | 38.0 | 3.56e-01 | 78.7% | 73.6% |
D4
medium
residues 65-208
Domain cluster:
rep: hypothetical_protein_PBCV1_A449R__NP_048806__Paramecium_bursaria_Chlorella_virus_1__10506__D56-192
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02940.21 best | mRNA_triPase | 31.0 | 3.00e-07 | 52.8% | 29.4% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3bgyA00 | 3.20.100.10 | Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › mRNA triphosphatase Cet1-like | 0.92 | 89.0 | 7.44e-01 | 100.0% | 65.0% |
| 1r0uA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.59 | 32.0 | 3.26e-01 | 100.0% | 51.4% |
| 6lofA00 | 2.40.155.10 | Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein | 0.58 | 35.0 | 3.41e-01 | 91.0% | 53.7% |
| 5bw0F00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.57 | 25.0 | 3.05e-01 | 100.0% | 61.5% |
| 2g16B00 | 2.40.155.10 | Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein | 0.52 | 32.0 | 3.13e-01 | 91.0% | 53.4% |
| 4wrnA02 | 2.60.40.3210 | Mainly Beta › Sandwich › Immunoglobulin-like › Zona pellucida, ZP-N domain | 0.50 | 25.0 | 2.91e-01 | 99.3% | 62.9% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1395021 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.95 | 92.0 | 7.69e-01 | 100.0% | 64.3% |
| 4793345 | 9.3.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Quinohemoprotein amine dehydrogenase A chain, domain 3-like | 0.71 | 28.0 | 3.21e-01 | 100.0% | 46.7% |
| 3714275 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.71 | 63.0 | 4.95e-01 | 100.0% | 48.7% |
| 3599872 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.70 | 56.0 | 4.44e-01 | 100.0% | 43.7% |
| 5081327 | 5084.1.1.0 ↗ | beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like | 0.69 | 26.0 | 2.97e-01 | 100.0% | 45.1% |
| 872 | 9.9.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Hypothetical protein YwiB › Hypothetical protein YwiB › DUF1934 | 0.59 | 32.0 | 3.26e-01 | 100.0% | 51.4% |
| 3587744 | 9.9.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Hypothetical protein YwiB › Hypothetical protein YwiB › DUF1934 | 0.56 | 32.0 | 3.30e-01 | 100.0% | 56.4% |
| 3615961 | 9.15.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › TLDC domain of oxidation resistance protein 2 › TLDC domain of oxidation resistance protein 2 › TLD | 0.51 | 36.0 | 3.42e-01 | 73.6% | 88.6% |
D5
medium
residues 431-496_642-666
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2pvpA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.61 | 31.0 | 3.60e-01 | 76.9% | 67.2% |
| 7r8iA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.58 | 39.0 | 3.04e-01 | 70.3% | 76.5% |
| 1usyC00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 38.0 | 2.79e-01 | 72.5% | 44.9% |
| 1k3eB02 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.53 | 29.0 | 2.83e-01 | 75.8% | 43.8% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3585180 | 109.4.1.1316 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf, HAT_PRP39_N, HAT_PRP39_C | 0.58 | 39.0 | 2.36e-01 | 100.0% | 9.9% |
| 3787561 | 7581.1.1.22 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N, ketoacyl-synt | 0.54 | 37.0 | 2.69e-01 | 72.5% | 67.2% |
| 3009291 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.50 | 42.0 | 2.76e-01 | 97.8% | 92.0% |