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mRNA_capping_enzyme_large_subunit

Euk-Vir

Monkeypox_virus

mRNA_capping_enzyme_large_subunit__YP_010377095__Monkeypox_virus__10244

Identity

Accession:
YP_010377095 ↗
Protein ID:
mRNA_capping_enzyme_large_subunit
Kingdom:
euk

Quality

71.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Monkeypox_virus

TaxID: 10244

Cluster

View cluster (35 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 32-226
PDB
Domain cluster: rep: large_subunit_of_mRNA_capping_enzyme__YP_232988__Vaccinia_virus__10245__D28-151_168-191
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10640.15 best MCEL_TPase 304.5 3.80e-91 98.5% 96.5%
D2 high residues 238-394
PDB
Domain cluster: rep: Salt_Pond_R1_B_H2O_MG_scaffold_1_prodigal-single.1__X__X__00295__D161-347
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF21004.4 best MCEL_GT_NTPase 132.5 7.70e-39 64.3% 88.5%
D3 high residues 398-521
PDB
D4 medium residues 565-589_601-669
PDB
Domain cluster: rep: guanylyltransferase__YP_009702667__African_swine_fever_virus__10497__D623-698
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vdwG00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.90 87.0 5.95e-01 100.0% 36.6%
3bgvD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.86 81.0 5.68e-01 100.0% 37.7%
3ua3A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.76 71.0 5.68e-01 100.0% 64.7%
1d2gA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 63.0 4.96e-01 97.9% 47.9%
1af7A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 63.0 4.93e-01 96.8% 68.0%
4fzvA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 59.0 4.44e-01 90.4% 38.5%
3v97B04 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.70 60.0 4.63e-01 93.6% 42.8%
4obxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 63.0 4.63e-01 98.9% 43.8%
2py6A03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 62.0 5.00e-01 98.9% 58.3%
3icoA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.68 58.0 4.31e-01 94.7% 73.0%
7x0hC01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 47.0 4.17e-01 72.3% 52.6%
2w9xA02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.67 59.0 4.50e-01 98.9% 64.4%
4yv7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 46.0 3.94e-01 72.3% 47.1%
4rsmA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 46.0 3.96e-01 72.3% 48.7%
3q41B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 46.0 3.80e-01 97.9% 40.3%
3g1wA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 45.0 3.90e-01 72.3% 50.0%
4y9tA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 44.0 3.65e-01 72.3% 44.3%
4evqA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 44.0 3.75e-01 72.3% 43.7%
1xknA00 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.63 47.0 3.19e-01 78.7% 94.6%
2wteA01 3.40.50.11700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 44.0 3.94e-01 73.4% 56.5%
4evsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 44.0 3.67e-01 73.4% 41.5%
4pe5B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 47.0 3.92e-01 97.9% 44.7%
7s6eA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 45.0 4.02e-01 96.8% 53.0%
3i45A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.62 43.0 3.56e-01 72.3% 40.0%
2qm0A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.62 55.0 4.10e-01 100.0% 63.2%
7rbpA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.62 52.0 4.14e-01 93.6% 46.2%
1inlD01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 53.0 4.10e-01 97.9% 44.5%
6qmmA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 53.0 4.03e-01 95.7% 41.1%
1pf5A00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.61 45.0 4.07e-01 78.7% 80.0%
2qu7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 41.0 3.69e-01 72.3% 56.5%
2o0jA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 51.0 3.78e-01 96.8% 44.1%
6yb3A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 47.0 3.63e-01 90.4% 94.5%
6yuqA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 51.0 3.85e-01 98.9% 68.7%
2d2eA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.65e-01 92.6% 52.3%
1eljA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.57 37.0 2.97e-01 74.5% 33.3%
1utbB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.57 38.0 3.41e-01 81.9% 50.0%
7pcrA01 3.40.50.10710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Metallo-hydrolase/oxidoreductase 0.56 47.0 4.06e-01 94.7% 73.9%
3hutA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 45.0 3.88e-01 95.7% 55.3%
3r5xA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 34.0 3.55e-01 74.5% 65.9%
1z06A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 45.0 3.86e-01 94.7% 79.4%
2wjwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 47.0 3.96e-01 96.8% 67.5%
3nd5A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 42.0 3.55e-01 81.9% 72.4%
3ny7A00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.53 46.0 4.37e-01 100.0% 99.2%
3sg0A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 46.0 3.98e-01 98.9% 65.8%
4mptA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 46.0 4.04e-01 98.9% 63.3%
1usgA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 43.0 3.81e-01 96.8% 61.8%
3ckmA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 42.0 3.52e-01 94.7% 59.9%
1afwB01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.50 41.0 3.22e-01 100.0% 40.4%
7zdgC02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 43.0 3.26e-01 95.7% 51.7%
2j48A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 42.0 3.93e-01 94.7% 90.8%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1283690 2003.1.5.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.93 90.0 5.99e-01 100.0% 34.8%
3940459 2003.1.5.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.88 83.0 5.37e-01 100.0% 29.4%
3840812 2003.1.5.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.87 82.0 5.40e-01 100.0% 30.9%
4024234 2003.1.5.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.80 76.0 4.92e-01 100.0% 27.3%
3742078 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.75 64.0 4.78e-01 92.6% 43.0%
4029106 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.74 67.0 4.66e-01 100.0% 44.3%
4999848 2003.1.5.12 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase 0.72 63.0 4.56e-01 94.7% 40.0%
3899754 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.72 64.0 4.77e-01 96.8% 45.8%
3611281 2492.1.1.0 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like 0.69 54.0 4.36e-01 83.0% 84.0%
3218517 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.67 48.0 3.94e-01 93.6% 40.6%
3236889 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.67 47.0 4.55e-01 73.4% 69.5%
3787654 2003.1.7.4 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › Glucosamine_iso 0.65 57.0 4.23e-01 98.9% 52.9%
3386092 301.7.1.1 ↗ a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like › Ribonuc_L-PSP 0.65 46.0 4.30e-01 73.4% 82.6%
3970430 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.65 38.0 3.58e-01 76.6% 49.1%
3250012 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.64 56.0 4.35e-01 100.0% 88.2%
3898254 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.63 47.0 3.82e-01 98.9% 41.1%
4182585 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.63 45.0 4.34e-01 73.4% 67.6%
5061458 2007.1.14.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.63 43.0 4.29e-01 78.7% 67.0%
3938581 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.63 43.0 3.57e-01 72.3% 41.7%
4646075 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.62 53.0 4.05e-01 92.6% 40.7%
4001476 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.62 43.0 3.39e-01 72.3% 52.0%
3946229 2003.1.1.26 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Glyco_hydro_4 0.62 45.0 3.68e-01 77.7% 43.0%
3241495 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.61 46.0 3.59e-01 97.9% 37.1%
4215928 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.61 38.0 3.59e-01 72.3% 52.7%
3413941 7515.1.1.0 ↗ a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like 0.60 51.0 3.87e-01 95.7% 60.4%
3581159 2004.1.1.19 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.59 44.0 4.33e-01 80.9% 91.4%
3410973 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.59 50.0 3.94e-01 92.6% 63.1%
3948425 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.59 36.0 3.53e-01 73.4% 55.2%
3615611 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.59 49.0 3.86e-01 92.6% 67.5%
5045615 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.58 42.0 3.41e-01 77.7% 44.9%
3512953 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.57 49.0 3.40e-01 95.7% 65.9%
4000837 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.56 48.0 3.49e-01 93.6% 69.4%
3557377 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.56 48.0 4.07e-01 95.7% 61.9%
3842923 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.55 48.0 4.00e-01 98.9% 86.9%
3997975 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.54 46.0 3.53e-01 95.7% 67.4%
1669079 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.54 35.0 3.95e-01 80.9% 92.5%
3710119 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.54 46.0 3.22e-01 100.0% 72.1%
4937010 2007.6.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain 0.54 47.0 3.66e-01 98.9% 54.8%
3745227 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.52 46.0 3.77e-01 100.0% 58.9%
3968592 7581.1.1.0 ↗ a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like 0.51 42.0 3.78e-01 98.9% 63.7%
1196959 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.51 34.0 3.77e-01 81.9% 94.2%
3256493 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.50 44.0 3.71e-01 97.9% 95.6%
3716298 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 43.0 3.45e-01 98.9% 48.1%
4682177 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.50 38.0 3.28e-01 97.9% 49.7%
D5 medium residues 590-600_670-710
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ou2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.88 79.0 5.09e-01 96.2% 48.0%
5h02A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.86 75.0 5.05e-01 96.2% 59.0%
3g2mA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.85 74.0 5.09e-01 96.2% 64.2%
1af7A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.83 74.0 4.92e-01 100.0% 75.8%
5je6A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.82 74.0 4.73e-01 100.0% 44.2%
3vywA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.80 72.0 4.61e-01 100.0% 55.3%
3crvA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 60.0 4.07e-01 96.2% 68.5%
3x0dA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 64.0 4.51e-01 100.0% 71.5%
4w7sA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 59.0 3.81e-01 100.0% 50.4%
3ua3A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 61.0 4.21e-01 100.0% 71.7%
1f3lA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 62.0 4.43e-01 100.0% 73.4%
4m37A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 60.0 4.37e-01 100.0% 75.2%
2vf8B04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 56.0 3.85e-01 100.0% 25.5%
3dkpA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 58.0 3.80e-01 100.0% 50.8%
3eypA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.65 54.0 3.42e-01 100.0% 25.7%
4j0eA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 55.0 3.74e-01 100.0% 59.9%
6eudA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 51.0 3.64e-01 96.2% 62.6%
2oz8A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.61 49.0 3.26e-01 94.2% 26.7%
4i8iA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.60 48.0 3.23e-01 100.0% 49.0%
1ofuA02 3.30.1330.20 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Tubulin/FtsZ, C-terminal domain 0.59 47.0 3.96e-01 90.4% 77.4%
1p3y100 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.58 48.0 3.44e-01 100.0% 83.6%
2wp8J01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.57 47.0 3.36e-01 100.0% 40.9%
1un2A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.57 45.0 3.18e-01 92.3% 47.8%
4gnsA03 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.57 47.0 3.75e-01 100.0% 77.3%
4amuA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.55 43.0 3.22e-01 100.0% 39.3%
7zp2C02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.53 41.0 3.16e-01 98.1% 44.2%
5ezqA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 40.0 2.95e-01 96.2% 70.1%
2r75102 3.30.1330.20 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Tubulin/FtsZ, C-terminal domain 0.52 41.0 3.34e-01 90.4% 64.5%
2lcqA01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.51 41.0 3.27e-01 98.1% 41.5%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4877432 2003.1.5.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.92 86.0 5.80e-01 100.0% 72.0%
5046132 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.88 78.0 4.83e-01 96.2% 41.6%
5079481 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.85 77.0 5.22e-01 100.0% 59.4%
5057921 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.84 74.0 4.64e-01 96.2% 41.9%
362489 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.83 75.0 4.73e-01 100.0% 43.9%
4977257 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.82 73.0 4.62e-01 100.0% 41.6%
3668297 2003.1.5.115 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_29 0.80 73.0 4.88e-01 100.0% 55.7%
4001303 2003.1.5.111 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Rsm22 0.80 69.0 4.19e-01 96.2% 35.8%
3996100 2003.1.5.9 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NNMT_PNMT_TEMT 0.80 71.0 4.87e-01 100.0% 80.0%
3225154 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.79 70.0 5.09e-01 100.0% 74.1%
5030370 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.79 69.0 4.51e-01 100.0% 44.9%
4810431 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.78 68.0 4.82e-01 100.0% 67.9%
3957090 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.77 65.0 4.80e-01 94.2% 60.0%
None — 0.76 65.0 3.99e-01 100.0% 33.1%
3897328 2003.1.5.111 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Rsm22 0.76 66.0 3.96e-01 100.0% 31.7%
4972908 2007.1.1.15 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF2124 0.74 65.0 4.62e-01 100.0% 64.4%
3504537 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.74 64.0 4.12e-01 100.0% 49.6%
4957823 2007.1.1.15 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF2124 0.73 64.0 4.53e-01 100.0% 63.7%
3287115 2003.1.5.55 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA 0.72 65.0 4.75e-01 100.0% 78.5%
3236675 2003.1.5.55 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA 0.72 65.0 4.80e-01 100.0% 81.5%
3573676 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.72 63.0 4.23e-01 96.2% 48.6%
5046831 2003.1.5.55 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA 0.72 65.0 4.60e-01 100.0% 70.7%
3181379 2003.1.5.153 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_25 0.71 62.0 4.21e-01 96.2% 60.0%
None — 0.71 61.0 4.04e-01 96.2% 51.2%
3852439 3698.1.1.0 ↗ beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain 0.71 63.0 3.60e-01 100.0% 23.4%
3482592 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.71 61.0 4.21e-01 96.2% 62.4%
4025385 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.70 63.0 4.29e-01 100.0% 73.3%
4562891 3698.1.1.0 ↗ beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain 0.70 62.0 3.77e-01 100.0% 35.1%
3305241 2003.1.5.153 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_25 0.70 60.0 4.18e-01 100.0% 62.2%
3234237 3698.1.1.3 ↗ beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › PrmA 0.70 61.0 3.51e-01 98.1% 23.0%
4837050 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.69 62.0 4.40e-01 100.0% 69.3%
3599547 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.69 63.0 4.46e-01 100.0% 73.8%
3551867 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.69 59.0 4.26e-01 100.0% 74.2%
None — 0.68 60.0 4.19e-01 100.0% 64.1%
3604689 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.68 61.0 4.32e-01 100.0% 69.0%
3914988 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.68 60.0 3.97e-01 98.1% 50.7%
3400245 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.68 59.0 4.02e-01 98.1% 55.7%
4032968 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 57.0 4.06e-01 100.0% 52.0%
2670403 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.67 59.0 4.35e-01 100.0% 77.2%
3387168 2007.1.3.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › UPF0004 0.65 57.0 4.21e-01 100.0% 56.4%
3510742 2004.1.1.19 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.65 56.0 3.80e-01 100.0% 57.4%
4614430 2007.1.3.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › UPF0004 0.64 54.0 4.07e-01 100.0% 55.7%
3347271 101.1.2.396 ↗ alpha arrays › HTH › HTH › winged helix domain › WHD_ROQ1 0.61 51.0 3.78e-01 100.0% 89.0%
3728663 2003.1.1.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA 0.58 48.0 3.00e-01 100.0% 36.3%
4027472 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.51 44.0 2.82e-01 100.0% 45.1%
D6 medium residues 711-766
PDB
Domain cluster: rep: mRNA_capping_enzyme_large_subunit__YP_784299__Nile_crocodilepox_virus__1285600__D719-769
D7 medium residues 767-845
PDB