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major_capsid_protein

Euk-Vir

Human_herpesvirus_5

major_capsid_protein__YP_002608278__Human_herpesvirus_5__10359

Identity

Accession:: YP_002608278 ↗
Protein ID:: major_capsid_protein
Kingdom:: euk

Quality

73.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Human_betaherpesvirus_5

TaxID: 10359

Cluster

View cluster (34 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 18-77_124-186

PDB

D2 medium residues 228-304_354-388

PDB

Domain cluster: rep: major_capsid_protein__NP_065524__Alcelaphine_gammaherpesvirus_1__35252__D265-300_361-395

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	80.9	7.60e-23	70.5%	5.6%
PF03122.21	Herpes_MCP	32.9	2.30e-08	32.1%	2.5%

D3 medium residues 389-452_699-815_892-972_1017-1047_1105-1191_1319-1365

PDB

Domain cluster: representative

Pfam (6)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	101.9	3.40e-29	27.9%	9.7%
PF03122.21	Herpes_MCP	106.8	1.10e-30	20.8%	6.3%
PF03122.21	Herpes_MCP	63.5	1.30e-17	19.2%	6.2%
PF03122.21	Herpes_MCP	74.0	8.90e-21	15.7%	4.7%
PF03122.21	Herpes_MCP	29.3	2.80e-07	11.0%	3.2%
PF03122.21	Herpes_MCP	34.6	7.10e-09	7.7%	2.3%

D4 medium residues 843-891

PDB

Domain cluster: representative

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2v4jA03	3.30.413.10	Alpha Beta › 2-Layer Sandwich › Sulfite Reductase Hemoprotein; domain 1 › Sulfite Reductase Hemoprotein, domain 1	0.59	47.0	3.36e-01	100.0%	87.8%
2xheA03	3.90.830.10	Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a	0.56	39.0	3.11e-01	79.6%	33.9%
2co9A00	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.54	37.0	3.07e-01	75.5%	37.3%
1hjrA00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.53	38.0	2.83e-01	83.7%	25.3%
3qxzA02	1.10.12.10	Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2	0.52	35.0	3.39e-01	71.4%	85.0%
2qguA02	1.10.10.640	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › phospholipid-binding protein	0.52	38.0	3.41e-01	83.7%	82.1%

ECOD (13)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3868765	101.1.2.178 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_61	0.62	46.0	3.79e-01	81.6%	69.5%
3278304	103.18.1.0 ↗	alpha arrays › RuvA-C	0.62	44.0	4.54e-01	79.6%	100.0%
4159969	166.1.1.1 ↗	alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C	0.61	48.0	4.01e-01	100.0%	64.8%
3401272	174.1.1.29 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728	0.61	42.0	2.92e-01	73.5%	22.4%
4025289	192.29.1.197 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4110	0.61	41.0	3.56e-01	73.5%	65.9%
5047195	2003.1.1.20 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase	0.58	39.0	2.43e-01	71.4%	40.3%
4386562	110.1.1.28 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain › Dredd_2nd	0.56	43.0	3.48e-01	83.7%	44.2%
3174828	103.4.1.15 ↗	alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › PF28865	0.55	38.0	3.44e-01	77.6%	55.0%
4964216	5063.1.1.24 ↗	alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › PF26047	0.55	38.0	3.50e-01	73.5%	80.0%
3732473	2003.1.3.26 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › FMO-like, NAD_binding_8	0.54	45.0	2.59e-01	100.0%	75.9%
3527369	110.1.1.3 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain › DED	0.54	39.0	3.43e-01	85.7%	75.6%
3205239	145.1.1.0 ↗	alpha arrays › F-box domain › F-box domain › F-box domain	0.51	38.0	3.43e-01	85.7%	58.7%
3511108	170.2.1.27 ↗	alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain › DUF7041	0.51	38.0	3.49e-01	85.7%	65.7%

D5 medium residues 1048-1104

PDB

D6 medium residues 1192-1318

PDB

Domain cluster: rep: major_capsid_protein__NP_065524__Alcelaphine_gammaherpesvirus_1__35252__D1180-1286_1299-1321

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	200.5	5.80e-59	100.0%	9.2%