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membrane-associated_protein
Euk-VirBombali_ebolavirus
membrane-associated_protein__YP_009513281__Bombali_ebolavirus__2010960
Identity
- Accession:
- YP_009513281 ↗
- Protein ID:
- membrane-associated_protein
- Kingdom:
- euk
Quality
72.9
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Monjiviricetes›
Mononegavirales›
Filoviridae›
Orthoebolavirus›
Bombali_virus
TaxID: 2010960
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 21-50_89-158
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06389.17 best | Filo_VP24 | 94.7 | 9.20e-27 | 72.0% | 27.1% |
| PF06389.17 | Filo_VP24 | 36.9 | 3.90e-09 | 32.0% | 13.0% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7k3zG01 | 3.50.7.10 | Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL | 0.65 | 45.0 | 3.46e-01 | 71.0% | 76.5% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 50.0 | 3.59e-01 | 87.0% | 82.1% |
| 4cpgA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.61 | 37.0 | 4.37e-01 | 71.0% | 87.0% |
| 3llkA01 | 1.20.120.1960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › QSOX sulfhydryl oxidase domain | 0.61 | 46.0 | 4.68e-01 | 93.0% | 82.7% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.60 | 41.0 | 4.24e-01 | 86.0% | 73.7% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.60 | 43.0 | 3.30e-01 | 74.0% | 84.7% |
| 3kp9A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.59 | 41.0 | 3.55e-01 | 72.0% | 75.3% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 54.0 | 4.66e-01 | 100.0% | 88.2% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 44.0 | 3.81e-01 | 79.0% | 91.4% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.58 | 42.0 | 4.09e-01 | 74.0% | 86.4% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 41.0 | 3.66e-01 | 73.0% | 73.2% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 40.0 | 3.88e-01 | 73.0% | 84.8% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 42.0 | 3.67e-01 | 78.0% | 96.7% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 42.0 | 3.07e-01 | 79.0% | 83.0% |
| 3gzkA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 44.0 | 2.91e-01 | 87.0% | 43.6% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 39.0 | 3.79e-01 | 74.0% | 83.8% |
| 1r9dA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.54 | 46.0 | 2.76e-01 | 93.0% | 38.8% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 38.0 | 3.65e-01 | 73.0% | 82.1% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.54 | 32.0 | 3.40e-01 | 96.0% | 65.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.54 | 38.0 | 4.09e-01 | 74.0% | 94.1% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.53 | 44.0 | 4.20e-01 | 91.0% | 84.6% |
| 2nvnA00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.53 | 36.0 | 3.49e-01 | 72.0% | 94.2% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.53 | 37.0 | 3.97e-01 | 90.0% | 88.2% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.52 | 29.0 | 3.18e-01 | 100.0% | 64.6% |
| 3h5aD01 | 3.90.930.70 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › | 0.52 | 38.0 | 3.98e-01 | 91.0% | 87.5% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.52 | 36.0 | 3.57e-01 | 75.0% | 68.2% |
| 1fx8A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.51 | 45.0 | 3.39e-01 | 98.0% | 83.5% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.51 | 35.0 | 3.08e-01 | 71.0% | 50.3% |
| 1fc6A01 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.50 | 34.0 | 3.49e-01 | 70.0% | 96.9% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185604 | 3400.1.1.1 ↗ | a+b complex topology › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Filo_VP24 | 0.89 | 85.0 | 6.35e-01 | 100.0% | 61.9% |
| 1148074 | 3400.1.1.1 ↗ | a+b complex topology › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Filo_VP24 | 0.88 | 84.0 | 6.25e-01 | 100.0% | 62.6% |
| 4070520 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.69 | 49.0 | 3.76e-01 | 72.0% | 49.8% |
| 3689164 | 219.3.1.1 ↗ | a+b complex topology › Cysteine proteinases-like › AnkH, inserted middle domain › AnkH, inserted middle domain › DUF6606 | 0.65 | 53.0 | 3.60e-01 | 87.0% | 73.3% |
| 3617417 | 3065.1.1.0 ↗ | alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins | 0.64 | 52.0 | 4.78e-01 | 88.0% | 100.0% |
| 3710934 | 633.2.1.0 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein | 0.62 | 42.0 | 4.48e-01 | 70.0% | 81.1% |
| 4017064 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.60 | 49.0 | 4.14e-01 | 89.0% | 78.8% |
| 3227811 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 43.0 | 3.74e-01 | 78.0% | 62.6% |
| 3744818 | 101.1.1.213 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HRI2_3H | 0.57 | 31.0 | 3.52e-01 | 82.0% | 69.3% |
| 2530252 | 2500.1.1.3 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › PFL-like | 0.57 | 48.0 | 2.87e-01 | 91.0% | 44.8% |
| 4341991 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.56 | 48.0 | 2.80e-01 | 91.0% | 37.8% |
| 3396058 | 3361.1.1.1 ↗ | alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › RAC_head | 0.53 | 34.0 | 3.57e-01 | 80.0% | 72.2% |
| 2983210 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.52 | 42.0 | 4.04e-01 | 88.0% | 75.4% |
| 4255175 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.52 | 47.0 | 3.47e-01 | 100.0% | 82.3% |
| 4260426 | 3718.1.1.1 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT | 0.51 | 33.0 | 3.35e-01 | 72.0% | 66.0% |
| 3270283 | 609.1.1.1 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg | 0.50 | 35.0 | 3.19e-01 | 71.0% | 72.6% |
D2
medium
residues 51-88_159-251
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06389.17 best | Filo_VP24 | 124.2 | 8.90e-36 | 73.3% | 39.3% |
| PF06389.17 | Filo_VP24 | 61.8 | 1.00e-16 | 29.8% | 14.1% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4exrA01 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.66 | 32.0 | 4.05e-01 | 78.6% | 76.5% |
| 1fr3A00 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.56 | 25.0 | 3.42e-01 | 71.8% | 80.6% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185604 | 3400.1.1.1 ↗ | a+b complex topology › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Filo_VP24 | 0.92 | 77.0 | 6.24e-01 | 85.5% | 80.7% |
| 1148074 | 3400.1.1.1 ↗ | a+b complex topology › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Membrane-associated protein VP24 › Filo_VP24 | 0.84 | 71.0 | 5.74e-01 | 86.3% | 78.4% |
| 415 | 2.4.1.1 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE | 0.56 | 25.0 | 3.42e-01 | 71.8% | 80.6% |
| 3490231 | 5.1.4.37 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 | 0.54 | 40.0 | 2.89e-01 | 75.6% | 42.0% |
| 3709800 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.53 | 28.0 | 3.19e-01 | 74.0% | 67.4% |
| 3276895 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.52 | 41.0 | 2.87e-01 | 82.4% | 91.0% |
| 3337961 | 5.1.3.144 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › b-prop_At3g26010-like | 0.52 | 36.0 | 2.63e-01 | 77.9% | 26.7% |
| 3441395 | 5.1.3.159 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF7595 | 0.51 | 36.0 | 2.77e-01 | 74.0% | 47.1% |
| 3695943 | 12.3.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich | 0.50 | 36.0 | 2.79e-01 | 74.0% | 83.1% |