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membrane_protein_A38

Euk-Vir

Aotine_betaherpesvirus_1

membrane_protein_A38__YP_004940167__Aotine_betaherpesvirus_1__50290

Identity

Accession:
YP_004940167 ↗
Protein ID:
membrane_protein_A38
Kingdom:
euk

Quality

65.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 48-173
PDB
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 34.0 4.31e-01 90.5% 73.0%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 38.0 4.34e-01 100.0% 66.0%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 54.0 5.76e-01 77.0% 94.5%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 56.0 5.95e-01 80.2% 96.3%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 40.0 3.98e-01 96.8% 53.9%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 53.0 5.65e-01 79.4% 97.2%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 36.0 4.36e-01 99.2% 76.5%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.69 44.0 4.72e-01 82.5% 73.6%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 38.0 4.08e-01 99.2% 62.0%
1ldjA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 47.0 4.74e-01 77.8% 71.2%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 35.0 4.23e-01 98.4% 79.5%
4uf1A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.64 34.0 3.38e-01 74.6% 46.7%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 43.0 4.73e-01 73.0% 86.3%
4rfsS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.63 48.0 4.26e-01 81.7% 57.8%
3rlbA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.62 47.0 4.21e-01 78.6% 81.8%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.61 33.0 3.51e-01 99.2% 58.6%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.61 38.0 4.65e-01 96.0% 97.5%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 45.0 4.01e-01 86.5% 52.7%
2i6hA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 29.0 3.30e-01 81.7% 58.3%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.61 43.0 3.75e-01 72.2% 92.6%
1jt6A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 46.0 4.52e-01 93.7% 76.6%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 40.0 4.48e-01 75.4% 89.8%
3bjbD00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 45.0 4.03e-01 88.9% 58.6%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.58 39.0 3.18e-01 100.0% 37.9%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 34.0 3.72e-01 94.4% 69.2%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 41.0 3.33e-01 71.4% 80.2%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.57 39.0 4.06e-01 74.6% 76.3%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.56 42.0 4.31e-01 79.4% 82.2%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.56 34.0 3.61e-01 100.0% 68.9%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 47.0 3.82e-01 94.4% 70.5%
1ek9A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.56 44.0 3.06e-01 84.1% 72.9%
3fr3B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 36.0 3.77e-01 76.2% 71.3%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 39.0 3.43e-01 73.0% 91.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 40.0 4.29e-01 77.8% 89.6%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.55 39.0 4.30e-01 79.4% 90.2%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.55 34.0 4.02e-01 80.2% 92.9%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 38.0 4.16e-01 72.2% 89.5%
1u3dA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 32.0 3.18e-01 76.2% 53.0%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 40.0 4.28e-01 77.8% 90.7%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 33.0 3.53e-01 76.2% 67.9%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 39.0 4.29e-01 77.8% 93.2%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 37.0 4.04e-01 70.6% 88.5%
4kwaB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 42.0 3.74e-01 92.1% 56.2%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 38.0 3.99e-01 73.0% 87.3%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 37.0 3.85e-01 70.6% 82.5%
3dbyL00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.52 43.0 3.38e-01 87.3% 57.3%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.51 45.0 3.16e-01 96.0% 46.5%
3bemB00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.51 38.0 3.18e-01 77.0% 73.2%
2qsaA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.51 33.0 3.62e-01 87.3% 82.2%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.50 42.0 4.25e-01 91.3% 91.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 39.0 3.65e-01 81.0% 80.9%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 31.0 3.53e-01 73.8% 81.4%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3811877 3937.1.1.0 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 0.80 44.0 3.96e-01 99.2% 41.2%
3678972 604.6.1.38 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › CASP_dom 0.77 41.0 4.44e-01 99.2% 60.6%
159607 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.74 38.0 4.34e-01 100.0% 66.0%
3943210 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.73 62.0 5.37e-01 91.3% 61.1%
5014076 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.73 61.0 5.09e-01 90.5% 60.5%
3422310 150.1.1.87 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Erg28 0.72 38.0 3.78e-01 100.0% 48.5%
3960584 5079.1.1.0 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain 0.72 61.0 5.42e-01 91.3% 64.4%
5042298 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.71 60.0 5.37e-01 92.1% 71.7%
3181479 1075.1.1.9 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › DUF3533 0.71 64.0 5.51e-01 99.2% 68.7%
3710920 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.70 59.0 5.33e-01 91.3% 66.3%
3589723 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 53.0 5.39e-01 80.2% 84.8%
5063209 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.69 61.0 5.09e-01 96.0% 92.6%
3264853 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 52.0 5.08e-01 80.2% 88.1%
3412574 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.68 36.0 3.57e-01 100.0% 48.5%
5065168 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.68 54.0 4.74e-01 88.1% 57.3%
3770290 4177.1.1.41 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EVC2_like 0.67 50.0 4.28e-01 77.8% 65.1%
3171345 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 36.0 3.21e-01 100.0% 35.6%
5012687 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.66 45.0 4.98e-01 72.2% 91.6%
4597483 5058.1.1.1 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.65 45.0 4.62e-01 72.2% 74.2%
4236667 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.65 55.0 4.33e-01 91.3% 79.2%
5013911 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.63 53.0 4.38e-01 91.3% 55.7%
4936252 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.63 44.0 4.87e-01 70.6% 95.8%
3784506 6058.1.1.1 alpha arrays › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › DAO_C 0.63 35.0 3.47e-01 77.0% 49.6%
5018283 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.63 36.0 4.00e-01 74.6% 70.0%
4024219 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.62 46.0 4.31e-01 77.8% 77.5%
3290433 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.61 42.0 4.79e-01 71.4% 97.8%
5043155 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.61 51.0 5.19e-01 92.1% 92.8%
3193852 150.5.1.57 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF27758 0.60 42.0 3.49e-01 71.4% 70.7%
3171374 5041.1.1.13 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATG2_CAD 0.60 48.0 4.69e-01 88.9% 76.4%
3215082 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.60 40.0 3.90e-01 100.0% 63.0%
3631218 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.59 41.0 4.67e-01 73.8% 95.8%
3692017 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 44.0 4.29e-01 79.4% 84.3%
5077399 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.58 48.0 4.52e-01 91.3% 74.8%
3930934 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.58 43.0 3.36e-01 78.6% 56.4%
4071221 191.1.1.3 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_5 0.57 44.0 4.56e-01 92.9% 88.1%
3517672 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.57 45.0 4.25e-01 83.3% 69.3%
3927027 3922.1.1.244 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Otopetrin 0.57 44.0 3.39e-01 80.2% 65.8%
3949413 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 36.0 3.56e-01 92.9% 59.3%
3274723 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.56 49.0 3.34e-01 98.4% 71.6%
4944710 604.5.1.82 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TrkA_C 0.56 38.0 4.30e-01 71.4% 91.6%
3180261 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.56 44.0 4.13e-01 84.9% 79.4%
3214189 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 39.0 4.26e-01 73.8% 91.4%
4154382 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.55 51.0 4.55e-01 100.0% 81.5%
1206502 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.55 40.0 4.29e-01 77.8% 89.6%
5050794 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.55 38.0 4.23e-01 72.2% 92.6%
3226579 5001.1.1.84 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz 0.55 45.0 3.43e-01 88.9% 78.0%
3923023 109.4.1.587 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mon2_C 0.54 36.0 2.65e-01 79.4% 24.1%
3637900 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.53 42.0 3.88e-01 84.1% 81.2%
3187407 633.10.1.4 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › DUF3429 0.53 39.0 3.58e-01 77.8% 100.0%
3696925 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.53 42.0 3.95e-01 96.8% 70.6%
5005528 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.52 37.0 4.12e-01 77.8% 94.0%
4117026 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.52 44.0 3.66e-01 92.9% 53.5%
56928 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.52 41.0 4.24e-01 88.9% 91.3%
3473134 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.52 47.0 4.24e-01 100.0% 90.3%
3214666 109.3.1.358 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Otopetrin 0.52 43.0 3.64e-01 91.3% 60.9%
4346691 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.50 38.0 3.03e-01 100.0% 40.8%
D2 medium residues 174-263
PDB
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.82 57.0 5.33e-01 71.1% 63.6%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.82 56.0 5.36e-01 70.0% 72.3%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 54.0 6.48e-01 71.1% 100.0%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.80 55.0 3.70e-01 71.1% 23.9%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 54.0 6.32e-01 70.0% 100.0%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.79 63.0 5.11e-01 94.4% 47.2%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.76 52.0 5.29e-01 70.0% 98.9%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 59.0 6.46e-01 94.4% 100.0%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 64.0 5.23e-01 93.3% 89.9%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.74 60.0 5.56e-01 92.2% 68.4%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 65.0 5.94e-01 96.7% 76.1%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.73 66.0 5.12e-01 100.0% 49.2%
2uxwA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 64.0 5.05e-01 98.9% 54.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 57.0 5.72e-01 85.6% 95.7%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.71 60.0 5.27e-01 92.2% 80.7%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 62.0 5.31e-01 97.8% 65.1%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 63.0 5.36e-01 100.0% 66.7%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 49.0 4.06e-01 71.1% 43.4%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 62.0 5.21e-01 98.9% 64.5%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 61.0 5.21e-01 98.9% 64.9%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 61.0 5.34e-01 97.8% 72.5%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 56.0 4.24e-01 87.8% 52.5%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.69 55.0 4.67e-01 94.4% 51.3%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.69 52.0 4.66e-01 78.9% 76.4%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.69 51.0 4.28e-01 80.0% 93.8%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 4.72e-01 90.0% 90.3%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.68 59.0 5.04e-01 98.9% 66.0%
3mfnB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 57.0 5.07e-01 93.3% 80.2%
2rccA01 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.65 56.0 4.09e-01 96.7% 61.4%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.65 56.0 5.18e-01 95.6% 96.5%
8iprA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.64 59.0 3.98e-01 98.9% 44.7%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.64 53.0 4.21e-01 90.0% 94.4%
1n1cA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.64 51.0 5.36e-01 95.6% 97.6%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 56.0 5.04e-01 96.7% 89.3%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.64 55.0 4.61e-01 96.7% 64.5%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 55.0 4.00e-01 96.7% 46.9%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 57.0 4.94e-01 100.0% 80.1%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 54.0 4.92e-01 96.7% 70.5%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.63 52.0 4.71e-01 93.3% 71.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 53.0 5.31e-01 98.9% 96.8%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.62 52.0 4.28e-01 92.2% 97.5%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 52.0 5.28e-01 100.0% 97.7%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.61 45.0 4.28e-01 76.7% 69.2%
2r17C00 1.25.40.660 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C 0.61 50.0 3.54e-01 92.2% 27.5%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.61 52.0 4.59e-01 96.7% 88.5%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.61 50.0 4.42e-01 92.2% 78.8%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.61 49.0 4.42e-01 87.8% 68.3%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 49.0 4.65e-01 93.3% 92.0%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.58 47.0 4.29e-01 88.9% 83.5%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 45.0 3.58e-01 84.4% 57.9%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 51.0 3.69e-01 100.0% 85.1%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 47.0 4.74e-01 98.9% 94.5%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.56 43.0 3.92e-01 84.4% 91.1%
2aw6A02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 38.0 2.91e-01 91.1% 31.2%
3d3mA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 40.0 3.39e-01 90.0% 53.4%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.88 61.0 5.19e-01 71.1% 55.6%
4259224 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 59.0 4.76e-01 70.0% 44.5%
4994917 3834.1.1.25 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.84 57.0 4.07e-01 70.0% 53.1%
3964934 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.84 57.0 3.41e-01 70.0% 13.5%
5039743 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.82 56.0 4.47e-01 70.0% 41.2%
3598168 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.80 55.0 4.39e-01 70.0% 90.3%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.80 54.0 4.73e-01 70.0% 63.1%
3600217 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.79 72.0 5.16e-01 98.9% 38.4%
4581983 5086.1.1.13 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB 0.79 54.0 4.59e-01 70.0% 58.6%
3941216 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.79 72.0 6.59e-01 98.9% 84.3%
3612403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.78 71.0 5.97e-01 98.9% 66.9%
3682662 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.77 69.0 6.06e-01 97.8% 77.7%
3743177 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.75 67.0 5.72e-01 98.9% 65.5%
54292 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.75 62.0 5.70e-01 92.2% 69.6%
3714307 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 65.0 5.38e-01 96.7% 66.3%
4460597 109.4.1.2258 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10, TPR_16, TPR_19 0.74 57.0 3.48e-01 94.4% 13.1%
3973833 3636.1.1.0 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.74 65.0 5.06e-01 96.7% 73.2%
4057126 109.4.1.1290 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_19 0.74 57.0 3.90e-01 94.4% 23.9%
4974234 604.12.1.141 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › 8xMP 0.74 58.0 5.97e-01 92.2% 88.2%
3406518 5054.1.1.61 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.74 65.0 4.71e-01 95.6% 70.6%
3962329 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.73 64.0 5.40e-01 98.9% 64.5%
3467780 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 59.0 4.84e-01 84.4% 54.7%
3820263 7016.1.1.0 extended segments › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain 0.73 66.0 5.60e-01 100.0% 71.0%
3476880 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.73 64.0 4.99e-01 100.0% 89.5%
3640629 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.72 64.0 5.21e-01 98.9% 57.6%
3957713 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.72 64.0 5.49e-01 100.0% 74.5%
3974230 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 62.0 5.91e-01 92.2% 94.3%
3950032 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.70 63.0 4.82e-01 100.0% 47.1%
3679043 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 63.0 5.19e-01 98.9% 60.0%
3474109 5054.1.1.61 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.70 62.0 4.42e-01 98.9% 63.3%
3590383 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.70 60.0 4.70e-01 96.7% 81.0%
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 61.0 5.75e-01 96.7% 90.0%
3978522 1014.1.1.1 alpha arrays › AopB › AopB › AopB › SseC 0.70 54.0 4.24e-01 84.4% 39.5%
3514956 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.69 62.0 4.83e-01 100.0% 48.7%
3488077 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 60.0 5.93e-01 93.3% 98.9%
5046472 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.69 59.0 5.86e-01 97.8% 96.8%
4027009 3636.1.1.0 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.68 62.0 4.62e-01 100.0% 56.8%
3796589 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.68 53.0 5.15e-01 94.4% 74.0%
3654589 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.67 56.0 5.70e-01 92.2% 98.9%
3604915 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 60.0 3.69e-01 100.0% 18.0%
3397045 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 58.0 4.85e-01 92.2% 77.9%
3273217 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 57.0 5.60e-01 94.4% 87.4%
3377135 604.6.1.2 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › ANTH 0.64 54.0 4.63e-01 94.4% 96.0%
3565045 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 55.0 4.63e-01 94.4% 63.3%
4180833 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.63 43.0 3.15e-01 71.1% 43.8%
3227820 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 53.0 4.61e-01 93.3% 67.6%
3936985 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.62 56.0 4.61e-01 96.7% 94.8%
3876801 109.4.1.3339 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_10, TPR_19 0.62 56.0 3.46e-01 100.0% 16.8%
3711098 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 52.0 4.67e-01 97.8% 78.4%
4027059 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.59 49.0 4.28e-01 97.8% 58.6%
3773122 5086.1.1.101 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.57 52.0 4.96e-01 98.9% 99.0%
4933204 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.54 45.0 4.30e-01 95.6% 80.9%