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membrane_protein_EE21
Euk-VirElephantid_betaherpesvirus_1
membrane_protein_EE21__YP_007969837__Elephantid_betaherpesvirus_1__146015
Identity
- Accession:
- YP_007969837 ↗
- Protein ID:
- membrane_protein_EE21
- Kingdom:
- euk
Quality
75.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephantid_betaherpesvirus_1
TaxID: 146015
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 32-165_240-255
Domain cluster:
rep: membrane_protein_EE47__YP_007969862__Elephantid_betaherpesvirus_1__146015__D50-159
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7f16R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.79 | 74.0 | 5.93e-01 | 100.0% | 91.7% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.79 | 74.0 | 5.81e-01 | 100.0% | 91.1% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.78 | 67.0 | 5.49e-01 | 91.3% | 100.0% |
| 4k5yA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.78 | 71.0 | 5.94e-01 | 98.0% | 99.2% |
| 8hixR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.77 | 72.0 | 5.74e-01 | 100.0% | 96.4% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.76 | 70.0 | 5.61e-01 | 100.0% | 94.7% |
| 7wujE01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.75 | 70.0 | 5.73e-01 | 100.0% | 93.9% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.75 | 67.0 | 5.42e-01 | 96.0% | 96.8% |
| 7sf7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 68.0 | 5.55e-01 | 100.0% | 92.3% |
| 5lweA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 68.0 | 5.52e-01 | 100.0% | 92.4% |
| 7eq1R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 68.0 | 5.48e-01 | 100.0% | 91.4% |
| 7xk2R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 65.0 | 5.30e-01 | 94.0% | 100.0% |
| 4jkvB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 68.0 | 5.13e-01 | 100.0% | 86.0% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 67.0 | 5.70e-01 | 99.3% | 100.0% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 39.0 | 5.23e-01 | 100.0% | 98.8% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.71 | 47.0 | 5.02e-01 | 93.3% | 76.2% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.70 | 64.0 | 5.15e-01 | 100.0% | 96.5% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 54.0 | 4.75e-01 | 80.7% | 95.3% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.69 | 38.0 | 4.95e-01 | 95.3% | 93.1% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 62.0 | 5.39e-01 | 100.0% | 98.2% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.65 | 31.0 | 2.53e-01 | 98.7% | 26.1% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.64 | 43.0 | 4.34e-01 | 94.7% | 68.7% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.63 | 42.0 | 4.28e-01 | 94.7% | 66.9% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 57.0 | 4.87e-01 | 100.0% | 97.9% |
| 3am6A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 57.0 | 4.91e-01 | 99.3% | 96.0% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 54.0 | 4.56e-01 | 100.0% | 93.8% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 56.0 | 4.61e-01 | 100.0% | 86.8% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.60 | 40.0 | 4.43e-01 | 93.3% | 87.9% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 53.0 | 4.74e-01 | 98.0% | 99.5% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 53.0 | 4.63e-01 | 97.3% | 98.6% |
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.58 | 43.0 | 4.03e-01 | 76.7% | 91.4% |
| 2yn7A00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.57 | 42.0 | 3.76e-01 | 75.3% | 99.1% |
| 7drjB01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.57 | 40.0 | 3.77e-01 | 71.3% | 90.2% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 37.0 | 4.07e-01 | 100.0% | 82.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 39.0 | 4.24e-01 | 93.3% | 87.5% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 40.0 | 3.95e-01 | 72.0% | 74.7% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.56 | 38.0 | 4.00e-01 | 73.3% | 76.7% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 40.0 | 4.00e-01 | 94.0% | 73.9% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 37.0 | 3.97e-01 | 74.0% | 80.8% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.52 | 40.0 | 3.92e-01 | 79.3% | 85.0% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 39.0 | 3.62e-01 | 77.3% | 73.7% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 43.0 | 3.44e-01 | 90.7% | 92.6% |
| 4o6mA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.51 | 41.0 | 3.75e-01 | 85.3% | 87.2% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4012167 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.81 | 76.0 | 5.91e-01 | 100.0% | 88.0% |
| 3894405 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.80 | 75.0 | 5.93e-01 | 100.0% | 91.6% |
| 3909392 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.79 | 73.0 | 5.78e-01 | 100.0% | 94.0% |
| 3904125 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.78 | 72.0 | 5.48e-01 | 100.0% | 85.4% |
| 3935392 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.77 | 72.0 | 5.58e-01 | 100.0% | 84.8% |
| 3234576 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.77 | 70.0 | 5.56e-01 | 97.3% | 92.4% |
| 3852696 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.77 | 71.0 | 5.55e-01 | 100.0% | 92.6% |
| 3929661 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.77 | 72.0 | 5.62e-01 | 100.0% | 89.0% |
| 3556942 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.77 | 71.0 | 5.72e-01 | 100.0% | 94.3% |
| 3926266 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.77 | 71.0 | 5.59e-01 | 100.0% | 89.0% |
| 3924629 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.76 | 71.0 | 5.46e-01 | 100.0% | 84.8% |
| 3243954 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.75 | 70.0 | 5.40e-01 | 100.0% | 85.7% |
| 3923749 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.75 | 70.0 | 5.50e-01 | 100.0% | 90.5% |
| None | — | 0.75 | 69.0 | 5.43e-01 | 99.3% | 99.0% | |
| 3933631 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.74 | 69.0 | 5.49e-01 | 100.0% | 92.1% |
| 3227718 | 5001.1.1.106 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Str | 0.74 | 69.0 | 5.34e-01 | 100.0% | 95.9% |
| 3878697 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.74 | 69.0 | 5.34e-01 | 100.0% | 97.1% |
| 3473655 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.74 | 68.0 | 5.03e-01 | 100.0% | 95.2% |
| 3230175 | 5001.1.1.19 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Tmemb_40 | 0.74 | 68.0 | 5.40e-01 | 100.0% | 86.4% |
| 3214549 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.74 | 68.0 | 5.27e-01 | 100.0% | 81.2% |
| 3922539 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.74 | 68.0 | 5.43e-01 | 100.0% | 95.2% |
| 3492033 | 5001.1.1.142 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF716 | 0.73 | 59.0 | 5.01e-01 | 89.3% | 53.6% |
| 3170645 | 5001.1.1.28 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 | 0.73 | 68.0 | 5.72e-01 | 100.0% | 98.0% |
| 3883169 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.73 | 67.0 | 5.48e-01 | 100.0% | 97.8% |
| 3263993 | 5001.1.1.123 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF29575 | 0.72 | 67.0 | 4.97e-01 | 100.0% | 81.1% |
| 3783128 | 5001.1.1.28 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 | 0.70 | 65.0 | 5.33e-01 | 100.0% | 94.3% |
| 3743161 | 4177.1.1.7 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Pil1 | 0.69 | 51.0 | 4.53e-01 | 77.3% | 92.3% |
| 3514777 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.68 | 46.0 | 4.79e-01 | 94.0% | 73.6% |
| 4964845 | 5001.1.1.292 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM | 0.68 | 63.0 | 5.51e-01 | 98.7% | 100.0% |
| 4018804 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.68 | 62.0 | 4.96e-01 | 100.0% | 89.5% |
| 3621584 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.67 | 62.0 | 5.06e-01 | 100.0% | 87.6% |
| 3425705 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.67 | 63.0 | 5.17e-01 | 100.0% | 92.7% |
| 5018555 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.67 | 47.0 | 5.22e-01 | 72.0% | 91.7% |
| 4943269 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.67 | 63.0 | 5.28e-01 | 100.0% | 97.9% |
| 4013063 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.67 | 61.0 | 4.93e-01 | 100.0% | 92.1% |
| 3312398 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 44.0 | 4.28e-01 | 96.7% | 60.6% |
| 3638458 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.66 | 61.0 | 4.90e-01 | 100.0% | 81.8% |
| 3390036 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.66 | 61.0 | 4.88e-01 | 100.0% | 85.6% |
| 3696501 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.65 | 60.0 | 4.77e-01 | 99.3% | 78.6% |
| 3189866 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.65 | 59.0 | 4.87e-01 | 99.3% | 96.3% |
| 4438308 | 5069.1.3.47 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › PsiE | 0.65 | 49.0 | 5.34e-01 | 87.3% | 93.6% |
| 3233462 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 43.0 | 4.61e-01 | 97.3% | 77.3% |
| 3373648 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.65 | 42.0 | 4.29e-01 | 92.0% | 66.2% |
| 4170329 | 605.1.1.158 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PsiE | 0.65 | 47.0 | 5.06e-01 | 89.3% | 86.9% |
| 4399761 | 192.29.1.166 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PsiE | 0.64 | 47.0 | 5.03e-01 | 87.3% | 87.7% |
| 3464835 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.64 | 41.0 | 4.44e-01 | 100.0% | 76.0% |
| 3579019 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.64 | 53.0 | 5.04e-01 | 89.3% | 82.8% |
| 3416085 | 5001.1.1.50 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF4791 | 0.63 | 57.0 | 5.23e-01 | 98.0% | 99.5% |
| 3389454 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.63 | 42.0 | 4.68e-01 | 94.0% | 85.0% |
| 3412554 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.63 | 41.0 | 4.46e-01 | 92.0% | 78.4% |
| 5009682 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 39.0 | 4.33e-01 | 99.3% | 77.5% |
| 3494901 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 44.0 | 4.60e-01 | 92.0% | 77.1% |
| 3511539 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.62 | 57.0 | 4.78e-01 | 100.0% | 92.9% |
| 3400786 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 44.0 | 4.48e-01 | 93.3% | 75.2% |
| 3934625 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 44.0 | 4.76e-01 | 93.3% | 88.0% |
| 3383516 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.61 | 41.0 | 4.40e-01 | 92.7% | 79.2% |
| 3753760 | 5082.1.1.0 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like | 0.61 | 49.0 | 4.39e-01 | 87.3% | 92.3% |
| 5045769 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.61 | 54.0 | 4.87e-01 | 98.7% | 98.6% |
| 3272341 | 5001.1.1.18 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF3522 | 0.61 | 55.0 | 4.91e-01 | 100.0% | 94.0% |
| 3991276 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.61 | 50.0 | 4.15e-01 | 89.3% | 82.2% |
| 3996622 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 45.0 | 4.62e-01 | 94.0% | 80.0% |
| 3453655 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 42.0 | 4.58e-01 | 92.0% | 87.2% |
| 4299710 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.59 | 45.0 | 4.27e-01 | 80.7% | 97.2% |
| 3401839 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 43.0 | 4.50e-01 | 92.7% | 85.2% |
| 3503767 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 43.0 | 4.45e-01 | 94.0% | 82.1% |
| 3918623 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.58 | 43.0 | 4.43e-01 | 94.7% | 80.7% |
| 4542751 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 45.0 | 4.48e-01 | 93.3% | 78.1% |
| 3433667 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.56 | 41.0 | 4.20e-01 | 100.0% | 76.0% |
| 3217694 | 174.1.1.31 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7027 | 0.56 | 45.0 | 4.43e-01 | 88.0% | 79.4% |
| 3367569 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 42.0 | 4.34e-01 | 92.7% | 81.4% |
| 5045453 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 44.0 | 4.54e-01 | 89.3% | 88.6% |
| 5051075 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.55 | 49.0 | 4.36e-01 | 95.3% | 78.0% |
| 3748369 | 174.1.1.3 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › p53-inducible11 | 0.55 | 39.0 | 4.00e-01 | 94.0% | 75.9% |
| 3937142 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.54 | 46.0 | 4.46e-01 | 96.0% | 81.2% |
| 3719886 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 39.0 | 4.10e-01 | 88.0% | 87.8% |
D2
medium
residues 166-239
Domain cluster:
representative
CATH (60)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.87 | 61.0 | 6.81e-01 | 73.0% | 100.0% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 61.0 | 6.22e-01 | 78.4% | 77.5% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 62.0 | 6.08e-01 | 78.4% | 72.8% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.83 | 61.0 | 6.51e-01 | 77.0% | 100.0% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 61.0 | 6.61e-01 | 77.0% | 95.2% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.82 | 61.0 | 5.53e-01 | 78.4% | 69.4% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 61.0 | 5.50e-01 | 78.4% | 99.0% |
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 61.0 | 5.90e-01 | 78.4% | 69.9% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.81 | 60.0 | 5.30e-01 | 78.4% | 71.7% |
| 7c4sB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.78 | 68.0 | 4.52e-01 | 95.9% | 34.1% |
| 6c1qB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.77 | 68.0 | 4.51e-01 | 95.9% | 90.0% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 57.0 | 5.39e-01 | 78.4% | 72.4% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.77 | 56.0 | 4.89e-01 | 77.0% | 61.8% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 56.0 | 5.33e-01 | 78.4% | 65.9% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.76 | 64.0 | 5.55e-01 | 100.0% | 60.7% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 66.0 | 4.68e-01 | 100.0% | 79.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 55.0 | 5.07e-01 | 78.4% | 74.5% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.74 | 52.0 | 3.70e-01 | 78.4% | 24.2% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.74 | 66.0 | 5.85e-01 | 100.0% | 74.5% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.73 | 65.0 | 4.65e-01 | 100.0% | 37.6% |
| 7um4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 63.0 | 4.40e-01 | 98.6% | 39.8% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 63.0 | 5.27e-01 | 100.0% | 62.7% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.72 | 64.0 | 4.46e-01 | 100.0% | 77.1% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 52.0 | 4.60e-01 | 77.0% | 56.4% |
| 3qhbA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 62.0 | 4.76e-01 | 100.0% | 79.9% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 61.0 | 4.52e-01 | 100.0% | 82.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.71 | 62.0 | 5.39e-01 | 100.0% | 73.3% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.71 | 57.0 | 5.29e-01 | 100.0% | 68.8% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 62.0 | 5.19e-01 | 100.0% | 80.0% |
| 4btfA01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.70 | 58.0 | 5.24e-01 | 90.5% | 92.0% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 50.0 | 5.23e-01 | 77.0% | 86.6% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.69 | 59.0 | 5.25e-01 | 100.0% | 66.7% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 60.0 | 4.36e-01 | 100.0% | 80.8% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.69 | 59.0 | 4.67e-01 | 100.0% | 48.5% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 4.32e-01 | 100.0% | 44.7% |
| 4adzA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.68 | 49.0 | 4.68e-01 | 77.0% | 66.7% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.68 | 59.0 | 5.05e-01 | 100.0% | 60.5% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 49.0 | 5.34e-01 | 78.4% | 100.0% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.67 | 58.0 | 4.97e-01 | 98.6% | 63.9% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 57.0 | 4.88e-01 | 100.0% | 61.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 56.0 | 4.89e-01 | 100.0% | 68.0% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.66 | 57.0 | 4.85e-01 | 100.0% | 94.4% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 52.0 | 5.44e-01 | 86.5% | 94.0% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.65 | 56.0 | 4.89e-01 | 100.0% | 71.4% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.65 | 47.0 | 4.45e-01 | 77.0% | 64.0% |
| 2wwxB00 | 1.20.1260.70 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.65 | 50.0 | 3.71e-01 | 94.6% | 31.5% |
| 4akgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.64 | 48.0 | 3.73e-01 | 79.7% | 37.2% |
| 1fouA01 | 1.10.246.30 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.64 | 48.0 | 4.87e-01 | 83.8% | 79.7% |
| 1cm5A00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.63 | 53.0 | 3.05e-01 | 95.9% | 44.3% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.61 | 56.0 | 4.66e-01 | 100.0% | 87.2% |
| 4mk6A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 57.0 | 4.14e-01 | 100.0% | 48.9% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 52.0 | 4.15e-01 | 94.6% | 68.5% |
| 8b9zK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 45.0 | 4.23e-01 | 83.8% | 68.1% |
| 4nphA02 | 1.20.1270.330 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 46.0 | 4.70e-01 | 95.9% | 100.0% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 49.0 | 3.85e-01 | 100.0% | 59.5% |
| 2o7tA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 51.0 | 3.76e-01 | 100.0% | 68.1% |
| 3fedA03 | 1.20.930.40 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain | 0.55 | 46.0 | 3.77e-01 | 100.0% | 76.8% |
| 4udsA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 45.0 | 3.46e-01 | 97.3% | 52.1% |
| 2cwyA00 | 1.10.3450.10 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like | 0.53 | 42.0 | 3.95e-01 | 87.8% | 84.9% |
| 1t11A02 | 1.10.3120.10 | Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain | 0.52 | 44.0 | 3.42e-01 | 93.2% | 68.1% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3833909 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.87 | 80.0 | 6.39e-01 | 100.0% | 54.3% |
| 3593736 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.86 | 65.0 | 5.77e-01 | 78.4% | 89.0% |
| 3230496 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.85 | 76.0 | 7.24e-01 | 97.3% | 96.5% |
| 3826941 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.84 | 77.0 | 5.71e-01 | 100.0% | 46.4% |
| 5057918 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.84 | 61.0 | 3.89e-01 | 75.7% | 45.6% |
| 3728842 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.83 | 76.0 | 5.87e-01 | 98.6% | 88.7% |
| 3441543 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.81 | 73.0 | 6.37e-01 | 98.6% | 79.1% |
| 3933315 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.81 | 55.0 | 4.91e-01 | 70.3% | 57.0% |
| 4967612 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.80 | 64.0 | 4.72e-01 | 94.6% | 34.6% |
| 3233367 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.79 | 57.0 | 4.83e-01 | 77.0% | 46.7% |
| 3914657 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.79 | 70.0 | 5.05e-01 | 100.0% | 77.1% |
| 3789363 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.79 | 59.0 | 3.58e-01 | 78.4% | 13.4% |
| 3917098 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.78 | 58.0 | 3.43e-01 | 78.4% | 11.2% |
| 3441901 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.78 | 68.0 | 6.69e-01 | 98.6% | 88.7% |
| 5013099 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.77 | 68.0 | 5.61e-01 | 100.0% | 78.5% |
| 3934203 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.76 | 67.0 | 4.42e-01 | 100.0% | 28.3% |
| 3969893 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 56.0 | 5.89e-01 | 78.4% | 89.2% |
| 3713097 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.76 | 66.0 | 4.13e-01 | 91.9% | 78.5% |
| 4220561 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.76 | 68.0 | 5.68e-01 | 100.0% | 63.6% |
| 3453285 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.76 | 68.0 | 5.55e-01 | 100.0% | 68.1% |
| 5026394 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.76 | 68.0 | 5.86e-01 | 100.0% | 79.1% |
| 4946275 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.75 | 55.0 | 3.72e-01 | 78.4% | 21.9% |
| 3724548 | 611.7.1.10 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Helo_like_N | 0.75 | 67.0 | 5.46e-01 | 98.6% | 93.3% |
| 3613499 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.74 | 66.0 | 5.08e-01 | 100.0% | 44.2% |
| 3262024 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.74 | 64.0 | 4.68e-01 | 100.0% | 71.6% |
| 5006607 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.74 | 66.0 | 6.36e-01 | 100.0% | 95.3% |
| 3276690 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 65.0 | 5.37e-01 | 100.0% | 84.4% |
| 3176858 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 64.0 | 5.23e-01 | 100.0% | 54.3% |
| 4983897 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 52.0 | 4.10e-01 | 77.0% | 80.0% |
| 4030051 | 2004.1.1.480 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 | 0.72 | 53.0 | 3.35e-01 | 78.4% | 14.9% |
| 5001811 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 63.0 | 5.90e-01 | 97.3% | 86.7% |
| 4963258 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.72 | 64.0 | 6.10e-01 | 98.6% | 90.6% |
| 3265711 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.69 | 61.0 | 4.89e-01 | 100.0% | 50.3% |
| 3599948 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 62.0 | 4.32e-01 | 100.0% | 44.7% |
| 3172162 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.69 | 57.0 | 5.10e-01 | 100.0% | 63.6% |
| 3620560 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.69 | 63.0 | 4.91e-01 | 100.0% | 58.0% |
| 3404174 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.68 | 60.0 | 5.37e-01 | 100.0% | 97.1% |
| 1118607 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.68 | 49.0 | 4.37e-01 | 78.4% | 52.7% |
| 3617965 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.67 | 61.0 | 4.43e-01 | 100.0% | 43.5% |
| 3692704 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.67 | 60.0 | 5.16e-01 | 100.0% | 78.3% |
| 3648594 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.66 | 57.0 | 5.10e-01 | 100.0% | 69.0% |
| 5028679 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.65 | 55.0 | 5.07e-01 | 100.0% | 74.8% |
| 3259629 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 56.0 | 5.14e-01 | 100.0% | 77.0% |
| 3278180 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.64 | 46.0 | 2.74e-01 | 75.7% | 10.9% |
| 3174531 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.64 | 48.0 | 4.39e-01 | 78.4% | 65.3% |
| 4955750 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.64 | 52.0 | 5.27e-01 | 93.2% | 94.7% |
| 3659411 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.64 | 55.0 | 4.90e-01 | 100.0% | 78.2% |
| 3255530 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.63 | 57.0 | 4.98e-01 | 100.0% | 66.4% |
| 3987966 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.62 | 48.0 | 4.32e-01 | 86.5% | 79.1% |
| 3348808 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.62 | 52.0 | 3.31e-01 | 100.0% | 17.3% |
| 3962320 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.61 | 53.0 | 4.57e-01 | 100.0% | 74.2% |
| 5077194 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.61 | 53.0 | 4.59e-01 | 100.0% | 75.6% |
| 3286958 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.61 | 52.0 | 3.81e-01 | 95.9% | 59.0% |
| 3240691 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.60 | 50.0 | 4.29e-01 | 100.0% | 55.6% |
| 4097778 | 191.1.1.10 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_6 | 0.58 | 50.0 | 4.11e-01 | 98.6% | 64.3% |