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membrane_protein_EE35
Euk-VirElephant_endotheliotropic_herpesvirus_5
membrane_protein_EE35__YP_009052058__Elephant_endotheliotropic_herpesvirus_5__768738
Identity
- Accession:
- YP_009052058 ↗
- Protein ID:
- membrane_protein_EE35
- Kingdom:
- euk
Quality
80.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephant_endotheliotropic_herpesvirus_5
TaxID: 768738
Cluster
View cluster (5 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 33-146
Domain cluster:
rep: protein_E14__YP_009179258__Elephant_endotheliotropic_herpesvirus_4__548914__D32-138
CATH (80)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.85 | 64.0 | 4.86e-01 | 77.2% | 78.6% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.85 | 63.0 | 6.30e-01 | 77.2% | 83.1% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.82 | 61.0 | 5.55e-01 | 77.2% | 77.0% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.82 | 62.0 | 4.75e-01 | 78.9% | 80.4% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 62.0 | 4.59e-01 | 78.9% | 44.4% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.81 | 61.0 | 6.02e-01 | 78.9% | 74.6% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.81 | 60.0 | 5.73e-01 | 78.1% | 67.7% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.80 | 73.0 | 7.17e-01 | 100.0% | 92.6% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.80 | 54.0 | 6.13e-01 | 77.2% | 90.8% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.80 | 59.0 | 5.93e-01 | 77.2% | 81.0% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 58.0 | 5.15e-01 | 77.2% | 67.5% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.78 | 53.0 | 5.39e-01 | 76.3% | 70.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.78 | 58.0 | 5.83e-01 | 78.1% | 78.6% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 54.0 | 5.30e-01 | 77.2% | 67.5% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.77 | 58.0 | 5.19e-01 | 78.1% | 59.1% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 58.0 | 4.42e-01 | 78.1% | 82.4% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.76 | 57.0 | 5.25e-01 | 78.1% | 74.7% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.76 | 49.0 | 4.90e-01 | 78.9% | 63.0% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 57.0 | 4.20e-01 | 78.1% | 74.2% |
| 1u8vB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.75 | 56.0 | 4.55e-01 | 78.1% | 47.4% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 56.0 | 5.42e-01 | 78.1% | 69.5% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.74 | 52.0 | 4.35e-01 | 71.1% | 59.1% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.74 | 53.0 | 4.82e-01 | 74.6% | 95.4% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.74 | 50.0 | 5.25e-01 | 78.1% | 77.5% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.73 | 47.0 | 5.46e-01 | 86.0% | 91.5% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.73 | 50.0 | 4.22e-01 | 70.2% | 53.8% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.73 | 66.0 | 5.80e-01 | 95.6% | 86.7% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 54.0 | 4.09e-01 | 78.1% | 89.0% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.72 | 54.0 | 4.90e-01 | 78.1% | 64.2% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.72 | 58.0 | 5.86e-01 | 84.2% | 99.1% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 53.0 | 4.04e-01 | 78.1% | 74.9% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 54.0 | 4.17e-01 | 78.9% | 63.5% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.72 | 39.0 | 4.55e-01 | 78.9% | 74.1% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 53.0 | 4.20e-01 | 76.3% | 95.5% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.72 | 46.0 | 4.84e-01 | 71.9% | 71.8% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 53.0 | 4.90e-01 | 78.1% | 61.5% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 54.0 | 4.42e-01 | 78.9% | 45.9% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.72 | 54.0 | 4.73e-01 | 78.9% | 65.1% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 53.0 | 4.91e-01 | 78.1% | 61.5% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.71 | 51.0 | 4.91e-01 | 77.2% | 64.9% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.71 | 53.0 | 4.66e-01 | 78.1% | 65.7% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.71 | 51.0 | 5.05e-01 | 76.3% | 70.6% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 52.0 | 4.15e-01 | 77.2% | 77.6% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 55.0 | 4.80e-01 | 83.3% | 92.6% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 57.0 | 4.34e-01 | 86.0% | 93.8% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.71 | 54.0 | 5.37e-01 | 81.6% | 77.3% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.70 | 64.0 | 5.80e-01 | 100.0% | 73.5% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 52.0 | 4.43e-01 | 78.1% | 89.4% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.70 | 52.0 | 3.84e-01 | 78.1% | 91.1% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 51.0 | 4.82e-01 | 78.9% | 63.5% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 53.0 | 4.11e-01 | 79.8% | 39.1% |
| 6l1xA01 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.69 | 61.0 | 3.98e-01 | 98.2% | 39.3% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 66.0 | 5.38e-01 | 100.0% | 68.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.69 | 51.0 | 4.89e-01 | 78.1% | 66.9% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 51.0 | 4.22e-01 | 77.2% | 69.5% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 50.0 | 4.17e-01 | 77.2% | 99.0% |
| 6d5xA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.67 | 50.0 | 4.60e-01 | 78.9% | 94.0% |
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.67 | 51.0 | 4.39e-01 | 78.9% | 83.7% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.67 | 50.0 | 4.55e-01 | 79.8% | 84.1% |
| 5bn3A04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.66 | 50.0 | 4.72e-01 | 100.0% | 65.5% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.66 | 58.0 | 5.29e-01 | 100.0% | 84.0% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.65 | 46.0 | 4.20e-01 | 78.9% | 54.5% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 48.0 | 3.70e-01 | 79.8% | 63.4% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.63 | 46.0 | 4.20e-01 | 76.3% | 79.1% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 48.0 | 3.69e-01 | 81.6% | 70.1% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.62 | 55.0 | 4.93e-01 | 100.0% | 78.2% |
| 3c4aA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.62 | 57.0 | 4.57e-01 | 100.0% | 63.0% |
| 6hwjA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.60 | 52.0 | 4.05e-01 | 93.0% | 79.2% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.59 | 47.0 | 4.27e-01 | 84.2% | 88.6% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.57 | 47.0 | 4.34e-01 | 87.7% | 93.8% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 40.0 | 3.86e-01 | 97.4% | 64.6% |
| 1t90A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.56 | 51.0 | 3.83e-01 | 100.0% | 75.0% |
| 5vbfA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.56 | 50.0 | 3.74e-01 | 98.2% | 75.0% |
| 7rkxR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 49.0 | 3.68e-01 | 94.7% | 47.4% |
| 3pqaB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 48.0 | 3.69e-01 | 96.5% | 81.6% |
| 1uxtA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.54 | 47.0 | 3.57e-01 | 95.6% | 76.2% |
| 1zu4A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.52 | 28.0 | 3.19e-01 | 92.1% | 65.5% |
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.52 | 45.0 | 3.46e-01 | 100.0% | 96.6% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 45.0 | 3.88e-01 | 98.2% | 61.0% |
| 7eqeB01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 38.0 | 3.38e-01 | 80.7% | 71.6% |
ECOD (72)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3612911 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.87 | 67.0 | 4.99e-01 | 79.8% | 78.4% |
| 3608743 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.84 | 63.0 | 4.67e-01 | 77.2% | 75.1% |
| 3791225 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.84 | 57.0 | 5.76e-01 | 75.4% | 68.7% |
| 3931312 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.84 | 63.0 | 6.24e-01 | 78.1% | 74.2% |
| 3853606 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.84 | 56.0 | 5.56e-01 | 74.6% | 65.0% |
| 3407718 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.83 | 59.0 | 5.71e-01 | 78.9% | 66.4% |
| 3579981 | 632.11.1.14 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › TMEM107 | 0.82 | 59.0 | 6.30e-01 | 73.7% | 94.0% |
| 3361214 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.82 | 61.0 | 5.80e-01 | 76.3% | 87.7% |
| 3585722 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.82 | 60.0 | 5.59e-01 | 76.3% | 64.3% |
| 3923952 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.82 | 60.0 | 5.75e-01 | 76.3% | 69.2% |
| 3606689 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.81 | 62.0 | 4.66e-01 | 78.9% | 77.3% |
| 3997912 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.81 | 57.0 | 5.69e-01 | 78.1% | 71.3% |
| 3729721 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 63.0 | 5.90e-01 | 81.6% | 82.2% |
| 3269163 | 150.1.1.31 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety | 0.80 | 60.0 | 4.39e-01 | 78.9% | 51.4% |
| 3253938 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.79 | 59.0 | 5.94e-01 | 77.2% | 76.5% |
| 3473688 | 3567.1.1.82 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Frag1 | 0.79 | 59.0 | 4.57e-01 | 77.2% | 44.7% |
| 3910521 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.79 | 56.0 | 5.82e-01 | 81.6% | 79.0% |
| 3862608 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.79 | 62.0 | 6.34e-01 | 81.6% | 84.5% |
| 3736582 | 150.1.1.55 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SesA | 0.78 | 61.0 | 5.72e-01 | 81.6% | 76.3% |
| 4037478 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.77 | 56.0 | 5.61e-01 | 74.6% | 93.0% |
| 3591771 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.77 | 69.0 | 6.34e-01 | 100.0% | 94.0% |
| 3819361 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.77 | 70.0 | 6.37e-01 | 100.0% | 92.0% |
| 4249009 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.77 | 57.0 | 5.62e-01 | 77.2% | 96.7% |
| 4501553 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.76 | 57.0 | 5.56e-01 | 78.1% | 99.2% |
| 3609099 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.76 | 57.0 | 6.27e-01 | 77.2% | 98.9% |
| 3239921 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.76 | 57.0 | 5.05e-01 | 78.9% | 61.8% |
| 4012236 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.76 | 70.0 | 6.20e-01 | 100.0% | 75.6% |
| 4354686 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.76 | 58.0 | 5.69e-01 | 78.9% | 98.3% |
| 3698208 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.76 | 69.0 | 6.48e-01 | 100.0% | 87.1% |
| 3478793 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.76 | 57.0 | 4.67e-01 | 78.1% | 47.0% |
| 3316598 | 611.7.1.13 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB10_N | 0.76 | 66.0 | 6.03e-01 | 100.0% | 73.1% |
| 3253939 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.74 | 55.0 | 5.44e-01 | 78.1% | 73.3% |
| 4561607 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.74 | 55.0 | 5.46e-01 | 77.2% | 96.7% |
| 3890798 | 161.1.1.7 ↗ | alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Serinc | 0.74 | 65.0 | 5.85e-01 | 100.0% | 69.4% |
| 3649632 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.74 | 67.0 | 6.26e-01 | 100.0% | 88.6% |
| 3600846 | 611.4.1.0 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like | 0.74 | 67.0 | 6.61e-01 | 99.1% | 97.5% |
| 3224746 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.74 | 55.0 | 5.40e-01 | 78.9% | 73.6% |
| 3282728 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.73 | 67.0 | 5.69e-01 | 100.0% | 62.8% |
| 3200052 | 1174.1.1.0 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 | 0.73 | 66.0 | 5.41e-01 | 100.0% | 72.9% |
| 4488596 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.73 | 54.0 | 5.45e-01 | 77.2% | 95.7% |
| 3779935 | 604.3.1.14 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › Serinc | 0.72 | 64.0 | 5.79e-01 | 100.0% | 71.6% |
| 4190833 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.72 | 54.0 | 5.38e-01 | 78.9% | 94.2% |
| 4297406 | 601.1.2.81 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Serinc | 0.72 | 63.0 | 5.64e-01 | 100.0% | 68.8% |
| 4137366 | 109.3.1.181 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Serinc | 0.72 | 65.0 | 5.81e-01 | 100.0% | 71.2% |
| 3939098 | 5082.1.1.0 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like | 0.71 | 54.0 | 4.34e-01 | 78.9% | 45.6% |
| 2324029 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.71 | 52.0 | 5.15e-01 | 81.6% | 72.1% |
| 3597275 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.71 | 52.0 | 5.21e-01 | 75.4% | 80.0% |
| 4195230 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.70 | 52.0 | 5.13e-01 | 76.3% | 95.0% |
| 3460324 | 3291.1.1.51 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PGG | 0.70 | 56.0 | 5.27e-01 | 85.1% | 75.7% |
| 3406569 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 51.0 | 4.81e-01 | 78.1% | 62.6% |
| 4274219 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.69 | 51.0 | 5.05e-01 | 77.2% | 93.3% |
| 3931313 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.68 | 62.0 | 5.42e-01 | 97.4% | 81.8% |
| 3246096 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.68 | 51.0 | 3.50e-01 | 77.2% | 61.8% |
| 4967728 | 5058.1.1.100 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PsiE | 0.68 | 47.0 | 4.35e-01 | 70.2% | 60.0% |
| 3300142 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.68 | 50.0 | 4.59e-01 | 77.2% | 80.7% |
| 3806117 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 53.0 | 4.79e-01 | 83.3% | 67.1% |
| 3453205 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.68 | 50.0 | 4.72e-01 | 78.1% | 65.0% |
| 4027655 | 5069.1.3.23 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DAD | 0.67 | 50.0 | 5.31e-01 | 77.2% | 89.0% |
| 1518845 | 601.41.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein › DUF3829_2nd | 0.67 | 46.0 | 4.73e-01 | 73.7% | 73.8% |
| 4013341 | 3755.4.1.3 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Helo_like_N | 0.67 | 59.0 | 5.79e-01 | 100.0% | 96.8% |
| 3674097 | 605.4.1.11 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › ALMT | 0.66 | 48.0 | 5.21e-01 | 80.7% | 91.6% |
| 3393338 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 51.0 | 4.66e-01 | 82.5% | 73.2% |
| 3384541 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 41.0 | 3.70e-01 | 77.2% | 48.4% |
| 5052913 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 55.0 | 4.86e-01 | 96.5% | 89.7% |
| 3173272 | 633.15.1.1 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › BCDHK_Adom3 | 0.59 | 52.0 | 4.57e-01 | 99.1% | 71.8% |
| 3228384 | 544.1.1.0 ↗ | alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 | 0.57 | 48.0 | 4.86e-01 | 89.5% | 98.2% |
| 3932652 | 5001.1.1.28 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 | 0.56 | 51.0 | 3.97e-01 | 97.4% | 46.7% |
| 3775753 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 48.0 | 2.92e-01 | 92.1% | 24.2% |
| 3476998 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 45.0 | 3.67e-01 | 98.2% | 44.9% |
| 3377464 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.53 | 49.0 | 4.32e-01 | 100.0% | 70.0% |
| 5048936 | 3960.1.1.0 ↗ | alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain | 0.52 | 38.0 | 3.78e-01 | 77.2% | 72.5% |
| 3266913 | 604.5.1.46 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TPR_SYVN1_N | 0.50 | 45.0 | 3.59e-01 | 100.0% | 66.1% |
D2
medium
residues 147-250