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membrane_protein_EE40
Euk-VirElephant_endotheliotropic_herpesvirus_5
membrane_protein_EE40__YP_009052063__Elephant_endotheliotropic_herpesvirus_5__768738
Identity
- Accession:
- YP_009052063 ↗
- Protein ID:
- membrane_protein_EE40
- Kingdom:
- euk
Quality
71.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephant_endotheliotropic_herpesvirus_5
TaxID: 768738
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-92
D2
medium
residues 93-233
Domain cluster:
representative
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.84 | 56.0 | 6.07e-01 | 78.0% | 78.7% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 56.0 | 4.72e-01 | 70.2% | 83.1% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 55.0 | 4.54e-01 | 70.9% | 82.7% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.76 | 54.0 | 5.38e-01 | 73.0% | 80.4% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.76 | 46.0 | 5.25e-01 | 74.5% | 79.6% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.74 | 54.0 | 4.54e-01 | 75.9% | 81.5% |
| 4bg5B00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.74 | 54.0 | 4.82e-01 | 75.9% | 61.8% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 54.0 | 4.37e-01 | 77.3% | 83.5% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 41.0 | 4.58e-01 | 95.0% | 72.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.70 | 53.0 | 5.19e-01 | 80.9% | 92.4% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.70 | 47.0 | 4.78e-01 | 71.6% | 69.0% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 52.0 | 4.21e-01 | 79.4% | 89.3% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 48.0 | 3.96e-01 | 72.3% | 82.9% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.67 | 59.0 | 5.26e-01 | 94.3% | 72.5% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.66 | 48.0 | 4.50e-01 | 75.9% | 97.2% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 51.0 | 5.33e-01 | 97.2% | 86.5% |
| 1r2jA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 53.0 | 5.29e-01 | 97.2% | 82.6% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 46.0 | 3.95e-01 | 73.0% | 86.0% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 50.0 | 5.21e-01 | 96.5% | 86.4% |
| 1fftC00 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.63 | 47.0 | 4.31e-01 | 77.3% | 59.5% |
| 6vxcA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.62 | 46.0 | 2.84e-01 | 75.2% | 47.6% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.62 | 33.0 | 3.47e-01 | 97.9% | 54.8% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.62 | 43.0 | 4.59e-01 | 78.7% | 81.8% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 42.0 | 4.54e-01 | 79.4% | 82.6% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 52.0 | 5.03e-01 | 97.9% | 82.2% |
| 6fmhB01 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.61 | 52.0 | 4.93e-01 | 94.3% | 100.0% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 42.0 | 4.73e-01 | 75.9% | 97.1% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 46.0 | 3.72e-01 | 80.1% | 83.3% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 42.0 | 4.45e-01 | 73.0% | 97.6% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 53.0 | 5.11e-01 | 98.6% | 86.1% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 48.0 | 3.84e-01 | 87.2% | 48.8% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 54.0 | 5.03e-01 | 100.0% | 84.6% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 53.0 | 5.19e-01 | 98.6% | 90.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 53.0 | 5.12e-01 | 98.6% | 87.7% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 43.0 | 4.27e-01 | 74.5% | 94.4% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 52.0 | 5.06e-01 | 98.6% | 88.8% |
| 2q83A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.56 | 48.0 | 4.02e-01 | 90.8% | 81.1% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.56 | 42.0 | 3.96e-01 | 76.6% | 79.1% |
| 4y9jA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 49.0 | 4.89e-01 | 98.6% | 94.0% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.55 | 39.0 | 4.26e-01 | 92.9% | 87.5% |
| 1u8vB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 50.0 | 4.32e-01 | 98.6% | 88.7% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 34.0 | 3.45e-01 | 87.9% | 63.3% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 4.05e-01 | 90.8% | 68.8% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 39.0 | 3.91e-01 | 78.0% | 95.3% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 46.0 | 4.15e-01 | 92.9% | 87.4% |
| 5tpmB00 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 32.0 | 3.27e-01 | 90.8% | 59.6% |
| 4xxiA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.52 | 36.0 | 3.56e-01 | 70.2% | 81.6% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3581398 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.84 | 61.0 | 6.29e-01 | 74.5% | 79.3% |
| 4665474 | 4177.2.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like | 0.84 | 62.0 | 4.95e-01 | 75.9% | 75.3% |
| 3211724 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.80 | 52.0 | 6.24e-01 | 75.9% | 96.8% |
| 3404485 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.79 | 60.0 | 5.22e-01 | 78.7% | 85.9% |
| 4467971 | 1189.1.1.9 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ATG17_like | 0.76 | 57.0 | 4.53e-01 | 78.0% | 77.8% |
| 3377150 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.75 | 52.0 | 5.68e-01 | 70.2% | 100.0% |
| 3698277 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.74 | 55.0 | 5.25e-01 | 75.9% | 86.3% |
| 3725261 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 56.0 | 4.36e-01 | 78.7% | 81.4% |
| 4593595 | 3835.1.1.0 ↗ | alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein | 0.74 | 51.0 | 4.40e-01 | 70.9% | 100.0% |
| 3600055 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.74 | 51.0 | 5.43e-01 | 75.9% | 80.0% |
| 4176577 | 601.1.2.3 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C | 0.73 | 58.0 | 6.09e-01 | 92.9% | 90.8% |
| 4295514 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.73 | 50.0 | 5.68e-01 | 75.9% | 93.3% |
| 3286925 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 49.0 | 5.26e-01 | 72.3% | 81.7% |
| 3932046 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 46.0 | 5.50e-01 | 70.9% | 100.0% |
| 3556822 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.72 | 51.0 | 4.15e-01 | 73.0% | 75.7% |
| 4992943 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.70 | 48.0 | 5.25e-01 | 76.6% | 85.2% |
| 3586382 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.70 | 48.0 | 5.49e-01 | 73.8% | 98.0% |
| 3832044 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.69 | 52.0 | 5.65e-01 | 78.0% | 95.7% |
| 3397093 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.69 | 49.0 | 5.21e-01 | 75.9% | 83.2% |
| 4020144 | 5038.2.1.0 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like | 0.67 | 54.0 | 5.38e-01 | 95.0% | 81.9% |
| 4955364 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.66 | 50.0 | 4.38e-01 | 79.4% | 74.4% |
| 3444302 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.66 | 48.0 | 4.96e-01 | 75.9% | 83.0% |
| 3872947 | 633.6.1.43 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › PF28139 | 0.66 | 47.0 | 4.67e-01 | 76.6% | 71.0% |
| 3894393 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 42.0 | 4.20e-01 | 76.6% | 61.3% |
| 1883676 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.65 | 52.0 | 4.56e-01 | 96.5% | 59.4% |
| 3442894 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.65 | 48.0 | 4.75e-01 | 75.9% | 89.7% |
| 5055960 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 37.0 | 3.98e-01 | 71.6% | 70.0% |
| 3277855 | 3562.1.1.3 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF6328 | 0.60 | 54.0 | 5.40e-01 | 99.3% | 95.9% |
| 134276 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.60 | 42.0 | 4.73e-01 | 75.9% | 97.1% |
| 4254266 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.60 | 50.0 | 4.64e-01 | 96.5% | 69.4% |
| 3614715 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.60 | 49.0 | 4.34e-01 | 100.0% | 60.5% |
| 4620905 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 52.0 | 4.07e-01 | 97.9% | 55.8% |
| 3247544 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 51.0 | 4.03e-01 | 96.5% | 51.9% |
| 3573122 | 7004.1.1.0 ↗ | 0.58 | 36.0 | 4.08e-01 | 85.8% | 80.9% | |
| 4945875 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.57 | 50.0 | 4.18e-01 | 98.6% | 87.1% |
| 5015138 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 41.0 | 4.10e-01 | 88.7% | 71.7% |
| 3979628 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.57 | 42.0 | 4.08e-01 | 98.6% | 69.7% |
| 3921484 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.56 | 47.0 | 3.89e-01 | 95.0% | 50.6% |
| 3406294 | 601.1.2.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17 | 0.55 | 44.0 | 4.58e-01 | 95.7% | 89.2% |
| 3247041 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.54 | 44.0 | 4.47e-01 | 96.5% | 88.6% |
| 5052572 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.53 | 42.0 | 4.07e-01 | 83.7% | 81.0% |
| 3894479 | 5057.1.1.13 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Strabismus | 0.52 | 44.0 | 4.49e-01 | 94.3% | 97.8% |
| 3998504 | 5057.1.1.13 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Strabismus | 0.52 | 45.0 | 4.48e-01 | 97.9% | 95.3% |
| 3331106 | 174.1.1.57 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › ABCC10_N | 0.51 | 39.0 | 3.49e-01 | 85.1% | 56.0% |
| 3510098 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.51 | 42.0 | 3.97e-01 | 98.6% | 71.4% |
| 3363015 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.51 | 36.0 | 3.68e-01 | 74.5% | 74.3% |
D3
medium
residues 234-300
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.80 | 64.0 | 4.94e-01 | 86.6% | 73.1% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.75 | 62.0 | 3.94e-01 | 91.0% | 56.8% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.74 | 60.0 | 5.10e-01 | 89.6% | 63.4% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.73 | 57.0 | 5.31e-01 | 89.6% | 68.2% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 61.0 | 5.69e-01 | 95.5% | 94.2% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 62.0 | 5.71e-01 | 100.0% | 92.2% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 58.0 | 5.89e-01 | 91.0% | 98.4% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.71 | 56.0 | 5.63e-01 | 89.6% | 100.0% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.70 | 55.0 | 5.12e-01 | 88.1% | 83.9% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 55.0 | 5.76e-01 | 88.1% | 98.3% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.69 | 55.0 | 5.59e-01 | 89.6% | 92.2% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 55.0 | 5.19e-01 | 88.1% | 74.4% |
| 3gnlB02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 57.0 | 5.74e-01 | 94.0% | 100.0% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 52.0 | 5.51e-01 | 86.6% | 96.6% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 54.0 | 5.14e-01 | 92.5% | 100.0% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.67 | 54.0 | 5.03e-01 | 91.0% | 70.6% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.66 | 54.0 | 4.99e-01 | 95.5% | 71.1% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 50.0 | 5.03e-01 | 86.6% | 85.1% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 50.0 | 4.43e-01 | 89.6% | 58.9% |
| 2w7nA00 | 1.10.10.2690 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.62 | 43.0 | 3.92e-01 | 74.6% | 70.2% |
| 3pxpA02 | 3.30.450.180 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.57 | 40.0 | 2.90e-01 | 79.1% | 25.1% |
| 4m52A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 42.0 | 2.99e-01 | 82.1% | 25.7% |
| 3djaA01 | 1.20.920.70 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.53 | 44.0 | 3.46e-01 | 94.0% | 84.1% |
| 3r0vA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 38.0 | 2.68e-01 | 82.1% | 42.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5016166 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.79 | 62.0 | 4.40e-01 | 89.6% | 29.5% |
| 3399823 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.79 | 65.0 | 4.70e-01 | 89.6% | 35.0% |
| 3614078 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.78 | 68.0 | 5.52e-01 | 94.0% | 57.5% |
| 4673482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 62.0 | 4.39e-01 | 91.0% | 30.0% |
| 4042007 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.76 | 62.0 | 5.28e-01 | 89.6% | 63.6% |
| 3175356 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 63.0 | 4.57e-01 | 89.6% | 43.4% |
| 3938318 | 4992.1.1.0 ↗ | extended segments › RelB-like › RelB-like › RelB-like | 0.76 | 62.0 | 5.08e-01 | 89.6% | 51.7% |
| 4298288 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.76 | 63.0 | 4.98e-01 | 91.0% | 100.0% |
| 3587894 | 101.1.2.49 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C | 0.72 | 63.0 | 4.66e-01 | 98.5% | 47.4% |
| 3962961 | 150.5.1.53 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE | 0.72 | 58.0 | 5.48e-01 | 89.6% | 78.8% |
| 5009792 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.67 | 53.0 | 5.42e-01 | 89.6% | 93.8% |
| 2391543 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.66 | 56.0 | 4.14e-01 | 100.0% | 47.2% |
| 3614305 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.63 | 54.0 | 3.40e-01 | 100.0% | 71.0% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.61 | 50.0 | 4.08e-01 | 97.0% | 82.1% |
| 3689216 | 7579.1.1.95 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Hydrolase_4 | 0.50 | 39.0 | 2.67e-01 | 91.0% | 48.6% |