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membrane_protein_EE42
Euk-VirElephantid_betaherpesvirus_1
membrane_protein_EE42__YP_007969858__Elephantid_betaherpesvirus_1__146015
Identity
- Accession:
- YP_007969858 ↗
- Protein ID:
- membrane_protein_EE42
- Kingdom:
- euk
Quality
87.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephantid_betaherpesvirus_1
TaxID: 146015
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 18-143
Domain cluster:
rep: membrane_protein_EE43__YP_007969859__Elephantid_betaherpesvirus_1__146015__D32-168
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.77 | 58.0 | 5.06e-01 | 77.8% | 90.8% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.76 | 58.0 | 4.68e-01 | 79.4% | 81.1% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 53.0 | 5.71e-01 | 77.0% | 84.1% |
| 1oj7A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.75 | 42.0 | 3.56e-01 | 72.2% | 34.3% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 51.0 | 4.95e-01 | 77.0% | 64.5% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 4.23e-01 | 77.8% | 79.3% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 4.33e-01 | 77.0% | 84.9% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 54.0 | 5.14e-01 | 77.0% | 66.4% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 4.41e-01 | 80.2% | 82.4% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 52.0 | 4.22e-01 | 75.4% | 71.9% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 54.0 | 4.33e-01 | 78.6% | 83.7% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.72 | 54.0 | 4.35e-01 | 79.4% | 82.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 50.0 | 5.25e-01 | 81.0% | 81.0% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 52.0 | 4.12e-01 | 77.8% | 71.1% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 52.0 | 4.41e-01 | 80.2% | 82.9% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 51.0 | 4.46e-01 | 81.7% | 86.2% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.66 | 48.0 | 4.28e-01 | 77.0% | 55.4% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.65 | 50.0 | 4.42e-01 | 98.4% | 56.6% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.63 | 43.0 | 4.18e-01 | 77.8% | 61.0% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 52.0 | 4.69e-01 | 92.1% | 86.5% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.62 | 46.0 | 4.61e-01 | 77.0% | 77.8% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 47.0 | 4.52e-01 | 81.7% | 79.7% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 50.0 | 4.18e-01 | 95.2% | 52.3% |
| 2j0nB00 | 1.20.1710.10 | Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like | 0.59 | 45.0 | 3.98e-01 | 80.2% | 75.9% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.59 | 41.0 | 2.97e-01 | 72.2% | 95.1% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 51.0 | 3.45e-01 | 98.4% | 25.2% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 54.0 | 4.64e-01 | 100.0% | 69.3% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.57 | 37.0 | 4.05e-01 | 74.6% | 79.0% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 42.0 | 4.07e-01 | 77.8% | 76.6% |
| 3oqlC00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.56 | 46.0 | 3.75e-01 | 88.9% | 96.3% |
| 1x9fA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 34.0 | 3.25e-01 | 92.1% | 54.4% |
| 3u52D00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.52 | 42.0 | 3.20e-01 | 88.9% | 69.5% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.50 | 41.0 | 3.16e-01 | 89.7% | 53.2% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4473674 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.79 | 58.0 | 6.23e-01 | 76.2% | 94.5% |
| 4944676 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.77 | 58.0 | 6.09e-01 | 77.8% | 91.3% |
| 5045176 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.77 | 55.0 | 5.99e-01 | 77.8% | 89.3% |
| 4508874 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.75 | 51.0 | 5.85e-01 | 73.8% | 92.6% |
| 3274839 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.74 | 56.0 | 4.24e-01 | 77.8% | 94.4% |
| 3466653 | 192.29.1.101 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N | 0.72 | 47.0 | 4.88e-01 | 77.0% | 71.3% |
| 4017622 | 611.9.1.8 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › PigL_N | 0.69 | 62.0 | 5.86e-01 | 99.2% | 88.7% |
| 3716237 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.68 | 50.0 | 4.31e-01 | 78.6% | 48.0% |
| 3330287 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.68 | 41.0 | 4.09e-01 | 73.8% | 56.3% |
| 3517647 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.68 | 47.0 | 5.32e-01 | 76.2% | 98.9% |
| 3176244 | 633.15.1.3 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › SOG2 | 0.67 | 57.0 | 5.34e-01 | 94.4% | 74.2% |
| 3470828 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.66 | 48.0 | 4.79e-01 | 77.0% | 73.8% |
| 4217891 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.65 | 50.0 | 4.72e-01 | 81.0% | 85.3% |
| 3336154 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.64 | 51.0 | 5.05e-01 | 83.3% | 81.5% |
| 4412648 | 1075.1.1.20 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR | 0.63 | 54.0 | 4.12e-01 | 94.4% | 86.6% |
| 3782656 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.63 | 52.0 | 4.33e-01 | 89.7% | 84.5% |
| 3700415 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 52.0 | 4.19e-01 | 98.4% | 46.0% |
| 3349368 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.62 | 51.0 | 4.21e-01 | 88.9% | 81.7% |
| 3231443 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.61 | 47.0 | 3.68e-01 | 81.0% | 88.3% |
| 3630853 | 1075.1.1.20 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR | 0.60 | 52.0 | 4.07e-01 | 92.1% | 75.8% |
| 3235287 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 45.0 | 3.45e-01 | 79.4% | 51.8% |
| 3785850 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.59 | 49.0 | 3.88e-01 | 90.5% | 70.9% |
| 4565740 | 5050.1.1.33 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_5 | 0.58 | 46.0 | 3.78e-01 | 98.4% | 45.0% |
| 4048969 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.57 | 46.0 | 3.81e-01 | 96.0% | 46.8% |
| 4476645 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 43.0 | 3.84e-01 | 96.0% | 55.9% |
| 4683248 | 5086.1.1.66 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR | 0.54 | 37.0 | 3.65e-01 | 93.7% | 63.6% |
| 3517330 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.54 | 41.0 | 3.43e-01 | 80.2% | 82.4% |
D2
medium
residues 144-238
Domain cluster:
rep: protein_E6__YP_009179244__Elephant_endotheliotropic_herpesvirus_4__548914__D199-274