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membrane_protein_EE62

Euk-Vir

Elephantid_betaherpesvirus_1

membrane_protein_EE62__YP_007969869__Elephantid_betaherpesvirus_1__146015

Identity

Accession:
YP_007969869 ↗
Protein ID:
membrane_protein_EE62
Kingdom:
euk

Quality

81.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 21-100
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 52.0 5.33e-01 77.5% 73.1%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.75 54.0 4.76e-01 75.0% 54.5%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.74 65.0 4.13e-01 100.0% 74.4%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.73 50.0 4.99e-01 71.2% 67.9%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 52.0 4.49e-01 76.2% 50.0%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.72 57.0 5.30e-01 98.8% 68.0%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 50.0 5.34e-01 72.5% 98.5%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 51.0 4.61e-01 75.0% 57.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 51.0 4.63e-01 75.0% 58.5%
7sf8A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 61.0 4.41e-01 100.0% 47.3%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 62.0 4.35e-01 100.0% 31.3%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.69 62.0 4.26e-01 100.0% 30.8%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.69 61.0 5.39e-01 100.0% 71.4%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 61.0 4.20e-01 100.0% 75.3%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.69 58.0 5.05e-01 100.0% 60.0%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 47.0 5.15e-01 72.5% 96.7%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.67 59.0 5.16e-01 98.8% 85.0%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 47.0 4.00e-01 73.8% 100.0%
2gnxA01 1.10.3450.30 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › 0.66 53.0 4.08e-01 95.0% 38.5%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.66 58.0 4.74e-01 98.8% 52.7%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 58.0 4.10e-01 100.0% 77.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 56.0 5.02e-01 100.0% 66.4%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 57.0 4.17e-01 100.0% 72.0%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.65 55.0 5.47e-01 91.3% 100.0%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.65 47.0 4.82e-01 97.5% 80.3%
7eptR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 57.0 4.02e-01 100.0% 35.0%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.64 45.0 3.90e-01 77.5% 47.2%
2c42A06 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.64 53.0 3.44e-01 92.5% 48.1%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.64 47.0 3.83e-01 78.8% 41.3%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.62 45.0 4.43e-01 76.2% 71.8%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.62 53.0 4.41e-01 96.2% 70.7%
3dytA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 53.0 4.14e-01 100.0% 86.8%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 54.0 4.32e-01 96.2% 88.0%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 54.0 4.45e-01 97.5% 54.9%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 51.0 4.20e-01 97.5% 51.0%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.61 52.0 4.67e-01 100.0% 70.0%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.59 39.0 3.73e-01 70.0% 55.7%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 52.0 3.66e-01 100.0% 71.5%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 49.0 4.06e-01 97.5% 51.0%
6lumG01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.59 52.0 4.68e-01 100.0% 91.1%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 44.0 4.46e-01 98.8% 82.5%
4bg5B00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.57 52.0 3.82e-01 100.0% 81.4%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 48.0 3.58e-01 100.0% 81.4%
3jckC00 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 46.0 3.03e-01 97.5% 26.7%
1t3dA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.54 42.0 3.58e-01 92.5% 49.3%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4963258 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.82 71.0 6.97e-01 100.0% 88.2%
3847053 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.79 54.0 5.56e-01 72.5% 74.7%
5052415 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.78 65.0 6.27e-01 100.0% 81.1%
4012236 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.77 53.0 4.18e-01 75.0% 35.6%
3503734 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.77 68.0 4.60e-01 100.0% 27.4%
3374547 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.76 69.0 4.62e-01 100.0% 30.1%
3547281 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.75 67.0 4.73e-01 100.0% 43.6%
3954925 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.75 67.0 4.75e-01 100.0% 33.6%
3219809 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.75 54.0 4.82e-01 77.5% 54.5%
3618939 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.75 67.0 4.82e-01 100.0% 49.3%
3584894 605.1.1.238 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › CNNM 0.75 53.0 5.15e-01 75.0% 85.6%
3626530 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 51.0 4.85e-01 72.5% 63.2%
3949413 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 48.0 4.03e-01 70.0% 40.0%
3933927 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.73 64.0 4.19e-01 100.0% 22.5%
3367685 192.15.1.80 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2985 0.72 65.0 5.27e-01 100.0% 55.3%
3749531 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.72 64.0 4.30e-01 100.0% 33.2%
4950702 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 60.0 5.19e-01 100.0% 59.2%
3963134 605.4.1.4 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 0.71 52.0 4.72e-01 76.2% 61.9%
4675002 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.71 47.0 3.98e-01 70.0% 41.5%
4947867 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.70 63.0 4.79e-01 100.0% 76.2%
3600968 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 62.0 5.12e-01 100.0% 60.4%
None 0.70 61.0 3.97e-01 100.0% 33.9%
3599715 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.70 60.0 4.96e-01 100.0% 58.1%
3248050 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 63.0 4.98e-01 100.0% 51.2%
3373643 5001.1.1.32 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a 0.69 61.0 4.60e-01 100.0% 42.5%
3393338 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 55.0 4.51e-01 100.0% 46.4%
3794663 604.3.1.27 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › EMC4 0.69 50.0 4.70e-01 77.5% 65.0%
4457403 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.69 50.0 3.45e-01 76.2% 96.3%
3684359 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.69 61.0 5.03e-01 100.0% 58.6%
3168919 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.69 61.0 4.20e-01 100.0% 73.9%
3536246 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.68 60.0 4.95e-01 100.0% 54.5%
3572847 604.1.1.162 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4716 0.68 49.0 4.39e-01 76.2% 55.7%
3497911 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.68 60.0 5.08e-01 100.0% 61.5%
5044921 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.68 60.0 4.62e-01 100.0% 50.8%
3485403 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.67 60.0 4.59e-01 100.0% 44.3%
2527147 4266.1.1.3 alpha bundles › Hyaluronidase domain-like › Hyaluronidase post-catalytic domain-like › Hyaluronidase post-catalytic domain-like › NagJ_C 0.66 56.0 4.97e-01 100.0% 64.2%
4963078 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.66 53.0 5.06e-01 100.0% 76.8%
3405546 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 55.0 4.63e-01 100.0% 53.8%
4012057 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.65 55.0 4.35e-01 100.0% 43.9%
4467968 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.65 52.0 4.69e-01 100.0% 61.7%
3493417 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.65 47.0 3.79e-01 77.5% 39.4%
3178547 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.65 45.0 3.07e-01 73.8% 83.8%
3502455 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.63 55.0 4.08e-01 100.0% 74.8%
5068844 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 50.0 4.73e-01 97.5% 73.7%
4161588 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.62 54.0 4.39e-01 100.0% 57.5%
3674356 5069.1.3.13 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › TB2_DP1_HVA22 0.62 52.0 5.22e-01 95.0% 97.5%
3336125 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.62 55.0 4.28e-01 97.5% 90.6%
4505154 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.62 54.0 3.73e-01 100.0% 30.5%
3991803 5059.1.1.34 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp 0.61 53.0 3.55e-01 98.8% 68.1%
3272866 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.60 53.0 4.16e-01 97.5% 50.6%
4428399 632.11.1.10 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA 0.60 50.0 4.48e-01 97.5% 66.4%
3613133 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 51.0 5.05e-01 96.2% 88.2%
3465074 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.59 54.0 4.61e-01 100.0% 88.8%
4653531 632.1.1.14 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › EzrA 0.59 49.0 4.45e-01 97.5% 66.4%
4367207 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.59 49.0 4.51e-01 97.5% 69.5%
4367113 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.59 49.0 4.48e-01 98.8% 69.5%
3589798 632.1.1.14 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › EzrA 0.59 49.0 4.64e-01 97.5% 76.8%
4318657 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.59 49.0 3.91e-01 97.5% 45.6%
4217891 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.58 48.0 3.93e-01 97.5% 48.7%
3960381 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.58 50.0 4.78e-01 100.0% 90.5%
4439930 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.58 48.0 3.89e-01 98.8% 47.4%
4997481 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.58 47.0 4.46e-01 98.8% 75.0%
5075878 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.57 44.0 4.41e-01 100.0% 83.7%
3889810 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 46.0 3.47e-01 100.0% 85.5%
3505840 1025.1.1.0 alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.55 44.0 4.30e-01 97.5% 80.0%
3608693 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.51 44.0 4.08e-01 98.8% 77.1%
D2 medium residues 101-140_155-254
PDB
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 55.0 4.49e-01 71.4% 83.6%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 53.0 4.39e-01 71.4% 87.9%
1w07A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 48.0 4.47e-01 74.3% 81.5%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.63 53.0 4.78e-01 91.4% 85.9%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 55.0 4.47e-01 95.7% 59.9%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.61 47.0 4.96e-01 87.1% 90.4%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.61 43.0 4.82e-01 92.9% 95.3%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 44.0 4.27e-01 75.0% 77.4%
4pypA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.60 52.0 3.69e-01 95.0% 89.9%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.60 50.0 4.35e-01 90.7% 95.9%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 43.0 3.71e-01 75.0% 61.2%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.59 47.0 4.81e-01 85.0% 92.0%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.58 43.0 4.67e-01 87.1% 90.8%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.58 42.0 4.56e-01 92.9% 89.0%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.58 45.0 4.94e-01 85.7% 98.3%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.58 46.0 4.15e-01 83.6% 70.2%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.57 45.0 4.89e-01 90.7% 100.0%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.57 44.0 4.72e-01 85.0% 96.6%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.57 44.0 4.58e-01 84.3% 88.3%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.57 46.0 4.94e-01 90.7% 99.2%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.56 40.0 4.10e-01 72.9% 86.0%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.56 46.0 4.48e-01 94.3% 78.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 40.0 4.29e-01 73.6% 98.3%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 47.0 4.22e-01 91.4% 78.6%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.55 44.0 4.19e-01 86.4% 78.0%
2a0bA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 35.0 3.77e-01 87.9% 75.4%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 45.0 4.57e-01 89.3% 98.5%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 35.0 3.77e-01 87.1% 77.6%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.53 37.0 4.23e-01 89.3% 100.0%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 37.0 3.56e-01 91.4% 63.9%
4qreA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 44.0 4.08e-01 90.0% 91.3%
3qkxB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 38.0 3.48e-01 75.7% 95.6%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 41.0 4.22e-01 86.4% 93.1%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 42.0 4.11e-01 90.7% 87.0%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 36.0 3.53e-01 75.7% 91.8%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3930630 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.79 74.0 5.89e-01 100.0% 65.7%
3238946 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.77 73.0 5.52e-01 100.0% 53.3%
3599032 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.74 52.0 4.36e-01 71.4% 91.7%
3216160 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.73 66.0 5.15e-01 98.6% 57.3%
3529043 3922.1.1.179 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › bMERB_dom 0.67 47.0 4.35e-01 71.4% 95.6%
3908311 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.66 59.0 4.79e-01 100.0% 79.6%
3467780 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.64 46.0 4.51e-01 72.9% 79.3%
5047572 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 58.0 4.83e-01 98.6% 60.9%
3233339 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.62 52.0 4.56e-01 90.0% 95.2%
3238458 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 45.0 3.74e-01 74.3% 71.8%
5040635 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 49.0 5.34e-01 90.0% 100.0%
3903240 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 44.0 3.58e-01 73.6% 66.8%
3466116 192.29.1.25 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like 0.61 50.0 5.33e-01 90.7% 100.0%
4995143 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 43.0 3.91e-01 75.0% 84.1%
3284088 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.60 49.0 5.08e-01 91.4% 94.6%
4870088 601.2.1.6 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_B562 0.59 41.0 4.31e-01 85.7% 78.2%
4959126 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 47.0 4.55e-01 85.7% 90.0%
3971908 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.58 41.0 4.28e-01 77.9% 79.2%
4383443 192.29.1.165 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29336 0.58 47.0 4.75e-01 85.7% 100.0%
3579241 192.29.1.50 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA 0.57 42.0 4.59e-01 76.4% 93.0%
3231965 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.57 41.0 3.99e-01 75.0% 76.9%
3879763 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.57 41.0 3.35e-01 74.3% 62.3%
3757067 604.1.1.16 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PEX11 0.56 49.0 4.27e-01 95.0% 68.6%
5058485 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 42.0 4.58e-01 89.3% 99.1%
3386958 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.55 43.0 4.58e-01 90.0% 93.6%
3969575 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.55 43.0 4.43e-01 86.4% 84.4%
4139505 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.54 40.0 4.18e-01 80.7% 83.1%
3378334 604.12.1.65 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 0.54 38.0 3.86e-01 70.7% 85.9%
4349682 192.29.1.33 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF2448 0.53 42.0 4.15e-01 82.9% 96.6%
4959549 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.52 42.0 3.85e-01 85.0% 70.8%
4953075 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.51 45.0 4.46e-01 95.0% 98.6%
3628013 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.50 37.0 3.16e-01 75.7% 83.6%