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membrane_protein_S22
Euk-VirSaimiriine_betaherpesvirus_4
membrane_protein_S22__YP_004940306__Saimiriine_betaherpesvirus_4__1535247
Identity
- Accession:
- YP_004940306 ↗
- Protein ID:
- membrane_protein_S22
- Kingdom:
- euk
Quality
77.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Saimiriine_betaherpesvirus_4
TaxID: 1535247
Cluster
View cluster (21 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 40-122
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.75 | 53.0 | 4.37e-01 | 72.3% | 43.9% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.73 | 50.0 | 5.29e-01 | 73.5% | 78.7% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 52.0 | 5.80e-01 | 85.5% | 95.4% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.72 | 51.0 | 5.12e-01 | 74.7% | 72.9% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 60.0 | 4.70e-01 | 100.0% | 42.9% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.71 | 54.0 | 4.78e-01 | 80.7% | 68.9% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 64.0 | 4.84e-01 | 100.0% | 45.9% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.70 | 59.0 | 4.85e-01 | 92.8% | 91.4% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.70 | 57.0 | 5.56e-01 | 89.2% | 82.6% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 50.0 | 4.83e-01 | 74.7% | 73.1% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.69 | 49.0 | 4.31e-01 | 73.5% | 54.5% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 61.0 | 4.67e-01 | 100.0% | 47.4% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.68 | 61.0 | 4.59e-01 | 100.0% | 47.3% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 49.0 | 4.77e-01 | 75.9% | 83.7% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 46.0 | 3.36e-01 | 71.1% | 24.5% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.68 | 54.0 | 4.53e-01 | 86.7% | 60.8% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.67 | 49.0 | 4.85e-01 | 80.7% | 73.6% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 52.0 | 3.66e-01 | 85.5% | 65.7% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 59.0 | 3.79e-01 | 100.0% | 22.2% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 57.0 | 4.67e-01 | 98.8% | 89.3% |
| 1blwC00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 57.0 | 4.76e-01 | 98.8% | 90.8% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 48.0 | 3.55e-01 | 84.3% | 40.8% |
| 2h21A02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.62 | 55.0 | 4.39e-01 | 98.8% | 91.5% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.60 | 50.0 | 3.73e-01 | 92.8% | 91.1% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.59 | 52.0 | 4.70e-01 | 100.0% | 77.8% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 45.0 | 4.34e-01 | 85.5% | 72.6% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 51.0 | 4.04e-01 | 100.0% | 82.2% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 52.0 | 3.70e-01 | 100.0% | 71.9% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 50.0 | 3.55e-01 | 96.4% | 96.8% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 51.0 | 4.26e-01 | 100.0% | 60.8% |
| 6c1qB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 47.0 | 3.31e-01 | 92.8% | 92.8% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 51.0 | 4.48e-01 | 97.6% | 89.9% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.56 | 45.0 | 3.99e-01 | 88.0% | 62.6% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 42.0 | 3.97e-01 | 80.7% | 73.3% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 50.0 | 4.27e-01 | 98.8% | 82.3% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 49.0 | 4.14e-01 | 100.0% | 63.6% |
| 2l1nA00 | 1.10.418.90 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Protein of unknown function DUF1823 | 0.55 | 40.0 | 3.49e-01 | 75.9% | 100.0% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.54 | 48.0 | 4.28e-01 | 98.8% | 88.2% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 49.0 | 4.83e-01 | 100.0% | 95.4% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 43.0 | 3.63e-01 | 90.4% | 77.1% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 44.0 | 4.03e-01 | 100.0% | 69.0% |
| 2id6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 3.43e-01 | 86.7% | 85.1% |
| 3ed5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.50 | 39.0 | 3.97e-01 | 84.3% | 88.1% |
ECOD (61)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3496559 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.77 | 69.0 | 5.07e-01 | 100.0% | 38.2% |
| 3810552 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.76 | 54.0 | 5.03e-01 | 73.5% | 67.0% |
| 5051406 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.76 | 68.0 | 5.05e-01 | 100.0% | 40.7% |
| 3477962 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.75 | 68.0 | 6.65e-01 | 100.0% | 93.3% |
| 3936765 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.74 | 67.0 | 4.89e-01 | 100.0% | 41.4% |
| 3700052 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.74 | 65.0 | 5.74e-01 | 100.0% | 67.5% |
| 3886185 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.73 | 61.0 | 4.39e-01 | 100.0% | 31.4% |
| 3954846 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 65.0 | 4.84e-01 | 100.0% | 40.0% |
| 3223355 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 66.0 | 4.85e-01 | 98.8% | 55.6% |
| 3736461 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.72 | 56.0 | 5.62e-01 | 85.5% | 81.2% |
| 3723517 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.71 | 55.0 | 5.47e-01 | 84.3% | 80.0% |
| 3739924 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.71 | 54.0 | 5.04e-01 | 85.5% | 64.8% |
| 3185717 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 63.0 | 4.42e-01 | 100.0% | 35.5% |
| 4039138 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.71 | 59.0 | 4.27e-01 | 92.8% | 35.0% |
| 3171516 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 60.0 | 4.28e-01 | 100.0% | 31.6% |
| 5050092 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 62.0 | 4.68e-01 | 100.0% | 45.9% |
| 3971778 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 61.0 | 4.65e-01 | 100.0% | 44.5% |
| 3668571 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.69 | 61.0 | 4.53e-01 | 100.0% | 44.1% |
| 3475009 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 61.0 | 4.51e-01 | 100.0% | 41.3% |
| 4022659 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 62.0 | 3.94e-01 | 100.0% | 89.9% |
| 3936772 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.69 | 59.0 | 4.47e-01 | 100.0% | 39.0% |
| 3754435 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.69 | 61.0 | 4.42e-01 | 100.0% | 38.3% |
| 4989412 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 62.0 | 4.44e-01 | 100.0% | 41.7% |
| 3391623 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 59.0 | 4.55e-01 | 100.0% | 42.1% |
| 5012016 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 62.0 | 4.66e-01 | 100.0% | 46.3% |
| 3491345 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 58.0 | 4.20e-01 | 100.0% | 32.0% |
| 4223336 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.69 | 61.0 | 4.61e-01 | 100.0% | 46.5% |
| 3481658 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 60.0 | 4.81e-01 | 100.0% | 55.3% |
| 4961013 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 60.0 | 4.63e-01 | 100.0% | 49.2% |
| 3533501 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 61.0 | 4.69e-01 | 100.0% | 47.9% |
| 3973240 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 60.0 | 4.56e-01 | 100.0% | 45.4% |
| 3476998 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 57.0 | 4.25e-01 | 100.0% | 35.1% |
| 3759765 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.68 | 61.0 | 4.44e-01 | 98.8% | 45.0% |
| 3275306 | 5059.1.1.33 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, SLC35F | 0.68 | 52.0 | 3.49e-01 | 81.9% | 42.5% |
| 3996236 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.68 | 59.0 | 4.47e-01 | 100.0% | 41.9% |
| 3970522 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.67 | 60.0 | 4.66e-01 | 100.0% | 49.2% |
| 3782487 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.67 | 52.0 | 4.44e-01 | 85.5% | 51.1% |
| 4995445 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 60.0 | 4.56e-01 | 100.0% | 46.2% |
| 4116357 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 60.0 | 4.55e-01 | 98.8% | 57.4% |
| 5027495 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.67 | 57.0 | 5.71e-01 | 96.4% | 94.1% |
| 3990896 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.66 | 57.0 | 4.25e-01 | 98.8% | 44.1% |
| 5054990 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 58.0 | 4.94e-01 | 100.0% | 73.2% |
| 3729123 | 5059.1.1.40 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › SLC35F, DUF3955 | 0.65 | 51.0 | 3.40e-01 | 84.3% | 44.1% |
| 5057841 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.64 | 57.0 | 4.10e-01 | 100.0% | 36.7% |
| 3656317 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 57.0 | 4.20e-01 | 100.0% | 40.0% |
| 3754034 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.64 | 46.0 | 4.59e-01 | 75.9% | 74.1% |
| 3958018 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 54.0 | 4.18e-01 | 100.0% | 41.0% |
| 3164482 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 56.0 | 4.22e-01 | 100.0% | 50.7% |
| 3165999 | 3291.1.1.213 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MscS_porin | 0.62 | 55.0 | 4.13e-01 | 100.0% | 86.2% |
| 3972311 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.61 | 50.0 | 3.48e-01 | 90.4% | 52.7% |
| 3179436 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 53.0 | 4.02e-01 | 100.0% | 44.7% |
| 5068364 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.59 | 51.0 | 3.53e-01 | 100.0% | 95.4% |
| 4941192 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.56 | 50.0 | 4.40e-01 | 100.0% | 88.8% |
| 4025583 | 636.1.1.0 ↗ | alpha arrays › SopE-like GEF domain › SopE-like GEF domain › SopE-like GEF domain | 0.56 | 41.0 | 3.23e-01 | 79.5% | 81.6% |
| 4009384 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.55 | 47.0 | 3.57e-01 | 100.0% | 44.2% |
| 4003499 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.54 | 46.0 | 4.19e-01 | 97.6% | 93.0% |
| 3476103 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.53 | 45.0 | 3.96e-01 | 100.0% | 62.4% |
| 3894751 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.53 | 44.0 | 3.85e-01 | 100.0% | 60.0% |
| 3621960 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.52 | 44.0 | 3.79e-01 | 100.0% | 57.8% |
| 3599376 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 45.0 | 3.14e-01 | 100.0% | 83.4% |
| 3245015 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.51 | 40.0 | 4.12e-01 | 92.8% | 91.3% |
D2
medium
residues 123-237
Domain cluster:
representative
CATH (60)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.82 | 36.0 | 4.11e-01 | 100.0% | 55.7% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.81 | 54.0 | 5.46e-01 | 72.2% | 68.4% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 54.0 | 4.30e-01 | 71.3% | 40.9% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 54.0 | 5.45e-01 | 74.8% | 75.2% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 54.0 | 5.27e-01 | 74.8% | 72.6% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.74 | 55.0 | 4.77e-01 | 76.5% | 53.8% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.73 | 53.0 | 5.35e-01 | 74.8% | 75.7% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 53.0 | 4.50e-01 | 74.8% | 49.4% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.73 | 53.0 | 5.10e-01 | 75.7% | 76.0% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 50.0 | 3.69e-01 | 71.3% | 74.4% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.71 | 48.0 | 5.02e-01 | 72.2% | 74.8% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 49.0 | 4.95e-01 | 72.2% | 80.3% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 48.0 | 4.80e-01 | 73.9% | 66.9% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 51.0 | 5.04e-01 | 74.8% | 73.3% |
| 1z23A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.70 | 52.0 | 4.64e-01 | 78.3% | 73.6% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.68 | 51.0 | 4.26e-01 | 77.4% | 47.2% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 48.0 | 5.00e-01 | 74.8% | 84.4% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 47.0 | 5.07e-01 | 72.2% | 91.8% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 49.0 | 4.54e-01 | 78.3% | 66.0% |
| 6d5xA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.66 | 48.0 | 4.36e-01 | 74.8% | 92.7% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.66 | 47.0 | 4.10e-01 | 72.2% | 84.5% |
| 2a0bA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.66 | 45.0 | 4.55e-01 | 89.6% | 68.6% |
| 1hx8A02 | 1.20.58.150 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › ANTH domain | 0.64 | 49.0 | 4.92e-01 | 80.9% | 88.0% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 45.0 | 4.28e-01 | 72.2% | 71.3% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.64 | 45.0 | 2.97e-01 | 73.0% | 49.8% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.64 | 45.0 | 4.39e-01 | 72.2% | 70.4% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.64 | 48.0 | 4.82e-01 | 78.3% | 97.4% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 46.0 | 4.88e-01 | 74.8% | 97.1% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 45.0 | 4.75e-01 | 93.0% | 81.6% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 45.0 | 4.61e-01 | 72.2% | 89.8% |
| 4o6mA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.63 | 53.0 | 4.52e-01 | 93.0% | 85.6% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 44.0 | 4.23e-01 | 72.2% | 68.5% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 43.0 | 4.31e-01 | 72.2% | 88.3% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.62 | 43.0 | 4.26e-01 | 72.2% | 71.5% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.61 | 45.0 | 4.40e-01 | 77.4% | 74.6% |
| 5haxA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 48.0 | 3.80e-01 | 86.1% | 64.2% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.60 | 55.0 | 4.96e-01 | 100.0% | 92.9% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.59 | 43.0 | 3.86e-01 | 76.5% | 76.1% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.59 | 39.0 | 4.03e-01 | 72.2% | 71.7% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 53.0 | 4.31e-01 | 100.0% | 88.1% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.57 | 50.0 | 4.30e-01 | 96.5% | 97.8% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.57 | 51.0 | 5.05e-01 | 97.4% | 94.2% |
| 2w2dD01 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.57 | 44.0 | 3.12e-01 | 85.2% | 54.1% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.57 | 51.0 | 4.71e-01 | 100.0% | 97.4% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 51.0 | 4.50e-01 | 96.5% | 68.3% |
| 3k7dA02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.57 | 43.0 | 3.43e-01 | 81.7% | 41.2% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.56 | 51.0 | 3.88e-01 | 98.3% | 45.9% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 50.0 | 4.44e-01 | 98.3% | 99.4% |
| 1yq3C02 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.55 | 40.0 | 4.10e-01 | 73.9% | 99.1% |
| 6c1qB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 48.0 | 3.69e-01 | 99.1% | 94.3% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 43.0 | 3.58e-01 | 86.1% | 50.5% |
| 5d0yA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.55 | 45.0 | 4.09e-01 | 95.7% | 65.8% |
| 1v9dB00 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.55 | 43.0 | 3.17e-01 | 85.2% | 64.5% |
| 3emlA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 48.0 | 3.66e-01 | 100.0% | 88.5% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 47.0 | 4.21e-01 | 95.7% | 90.6% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 43.0 | 3.34e-01 | 88.7% | 77.1% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 43.0 | 4.11e-01 | 95.7% | 95.7% |
| 3lpzA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 35.0 | 2.62e-01 | 72.2% | 40.4% |
| 7ep1B01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 42.0 | 3.28e-01 | 88.7% | 65.3% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 44.0 | 3.40e-01 | 95.7% | 67.6% |
ECOD (86)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3989144 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.89 | 85.0 | 6.63e-01 | 100.0% | 55.9% |
| 3849233 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 84.0 | 6.64e-01 | 100.0% | 54.5% |
| 3740175 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 84.0 | 6.56e-01 | 100.0% | 53.2% |
| 3964581 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 84.0 | 6.67e-01 | 100.0% | 54.8% |
| 3409798 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 81.0 | 6.44e-01 | 97.4% | 54.9% |
| 3936208 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 84.0 | 6.50e-01 | 100.0% | 55.6% |
| 3540947 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 83.0 | 6.50e-01 | 99.1% | 55.9% |
| 4023988 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 83.0 | 6.53e-01 | 100.0% | 55.7% |
| 3694381 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 83.0 | 6.58e-01 | 100.0% | 54.7% |
| 4281235 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 80.0 | 6.32e-01 | 97.4% | 55.5% |
| 3939603 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 83.0 | 6.49e-01 | 100.0% | 56.8% |
| 3415929 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 83.0 | 6.54e-01 | 100.0% | 55.8% |
| 5075726 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 82.0 | 6.42e-01 | 100.0% | 51.6% |
| 3577761 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 82.0 | 7.60e-01 | 100.0% | 82.9% |
| 3500534 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 82.0 | 6.53e-01 | 100.0% | 55.2% |
| 2473013 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 82.0 | 6.54e-01 | 100.0% | 56.7% |
| 3626734 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 82.0 | 6.48e-01 | 100.0% | 54.9% |
| 3386740 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 82.0 | 6.32e-01 | 100.0% | 50.0% |
| 3610437 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 81.0 | 6.53e-01 | 100.0% | 59.0% |
| 3169936 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 81.0 | 6.38e-01 | 100.0% | 56.8% |
| 3399094 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.86 | 81.0 | 6.41e-01 | 100.0% | 57.2% |
| 3481708 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.85 | 80.0 | 6.20e-01 | 100.0% | 53.9% |
| 3390912 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.85 | 79.0 | 6.21e-01 | 100.0% | 54.7% |
| 3403648 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.84 | 77.0 | 6.20e-01 | 100.0% | 57.7% |
| 54287 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.81 | 57.0 | 5.73e-01 | 73.0% | 72.2% |
| 3416752 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.81 | 75.0 | 5.90e-01 | 100.0% | 56.0% |
| 3511623 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.81 | 75.0 | 6.37e-01 | 100.0% | 66.7% |
| 3394147 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.80 | 74.0 | 5.83e-01 | 100.0% | 57.8% |
| 3486791 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.79 | 73.0 | 6.34e-01 | 98.3% | 69.4% |
| 3478731 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.79 | 74.0 | 6.20e-01 | 100.0% | 64.9% |
| 3927012 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.78 | 55.0 | 5.13e-01 | 72.2% | 68.6% |
| 3888824 | 601.1.2.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CD20 | 0.77 | 55.0 | 4.98e-01 | 73.0% | 64.0% |
| 4029489 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.76 | 54.0 | 4.99e-01 | 73.9% | 57.9% |
| 3586164 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.76 | 56.0 | 5.40e-01 | 76.5% | 77.7% |
| 3176858 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.75 | 55.0 | 5.11e-01 | 74.8% | 68.6% |
| 3855880 | 622.4.1.19 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › CD20 | 0.74 | 51.0 | 5.35e-01 | 70.4% | 90.5% |
| 3796225 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 50.0 | 4.89e-01 | 74.8% | 64.0% |
| 5079010 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 56.0 | 5.15e-01 | 79.1% | 64.8% |
| 4017168 | 150.1.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 | 0.73 | 54.0 | 4.88e-01 | 76.5% | 69.5% |
| 3332592 | 5069.1.1.62 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Chloroplast_duf | 0.73 | 51.0 | 5.21e-01 | 71.3% | 77.3% |
| 3528058 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.72 | 65.0 | 4.84e-01 | 100.0% | 65.4% |
| 3471897 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.72 | 55.0 | 5.16e-01 | 80.0% | 66.4% |
| 3715565 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.72 | 51.0 | 4.09e-01 | 73.0% | 43.6% |
| 3504253 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.71 | 50.0 | 4.90e-01 | 77.4% | 66.4% |
| 3231853 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.71 | 50.0 | 4.87e-01 | 72.2% | 71.2% |
| 3782470 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.71 | 50.0 | 5.05e-01 | 74.8% | 73.0% |
| 3827313 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.71 | 44.0 | 4.57e-01 | 70.4% | 66.4% |
| 3191086 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.71 | 56.0 | 4.49e-01 | 86.1% | 53.2% |
| 1019365 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.70 | 49.0 | 4.98e-01 | 72.2% | 81.7% |
| 3621652 | 3937.1.1.0 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 | 0.70 | 64.0 | 4.97e-01 | 100.0% | 98.4% |
| 4327699 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.70 | 54.0 | 3.85e-01 | 80.0% | 70.3% |
| 3363364 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.69 | 50.0 | 4.80e-01 | 75.7% | 74.8% |
| 5050794 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.69 | 50.0 | 5.42e-01 | 75.7% | 100.0% |
| 3876247 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 49.0 | 4.87e-01 | 74.8% | 90.8% |
| 3716023 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 48.0 | 3.29e-01 | 76.5% | 45.6% |
| 3719700 | 109.2.1.80 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › PF30299 | 0.65 | 51.0 | 3.67e-01 | 81.7% | 46.9% |
| 4978688 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.65 | 47.0 | 5.09e-01 | 74.8% | 93.7% |
| 3610769 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 48.0 | 4.59e-01 | 75.7% | 78.5% |
| 3170239 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 45.0 | 4.99e-01 | 72.2% | 93.3% |
| 3407916 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.63 | 46.0 | 4.50e-01 | 76.5% | 72.0% |
| 5083908 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.62 | 47.0 | 4.72e-01 | 81.7% | 79.2% |
| 4476645 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 50.0 | 4.25e-01 | 89.6% | 59.0% |
| 3227820 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 47.0 | 4.49e-01 | 82.6% | 96.4% |
| 3684013 | 5069.1.1.48 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PGG | 0.59 | 53.0 | 3.80e-01 | 99.1% | 74.0% |
| 3401837 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.59 | 51.0 | 4.16e-01 | 97.4% | 85.8% |
| 3806463 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.59 | 53.0 | 4.79e-01 | 99.1% | 96.1% |
| 3359510 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 53.0 | 4.80e-01 | 100.0% | 96.1% |
| 3625559 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 42.0 | 3.97e-01 | 76.5% | 74.5% |
| 3314513 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 52.0 | 4.66e-01 | 100.0% | 96.9% |
| 3828167 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.57 | 49.0 | 4.38e-01 | 93.0% | 88.7% |
| 5052771 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 46.0 | 4.63e-01 | 93.9% | 85.2% |
| 3436634 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.57 | 52.0 | 4.71e-01 | 100.0% | 92.9% |
| 5018554 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 45.0 | 4.80e-01 | 88.7% | 96.0% |
| 3436766 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.55 | 45.0 | 4.42e-01 | 86.1% | 96.0% |
| 3306743 | 192.29.1.101 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N | 0.55 | 48.0 | 4.55e-01 | 93.0% | 82.2% |
| 3316910 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.55 | 50.0 | 4.45e-01 | 96.5% | 94.2% |
| 3831449 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.54 | 49.0 | 4.37e-01 | 99.1% | 97.5% |
| 3196950 | 611.7.1.12 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Goodbye | 0.54 | 45.0 | 3.69e-01 | 88.7% | 63.9% |
| 4221094 | 611.9.1.6 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Ran-binding | 0.54 | 46.0 | 4.44e-01 | 91.3% | 96.2% |
| 3620861 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 49.0 | 4.67e-01 | 100.0% | 86.7% |
| 3242255 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.53 | 49.0 | 4.41e-01 | 100.0% | 84.2% |
| 3863010 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.52 | 47.0 | 3.23e-01 | 100.0% | 47.9% |
| 3347110 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.52 | 44.0 | 3.46e-01 | 92.2% | 72.4% |
| 3685679 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 45.0 | 4.04e-01 | 93.0% | 90.3% |
| 3175132 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.51 | 45.0 | 3.52e-01 | 100.0% | 100.0% |
| 3626980 | 5059.1.1.34 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp | 0.50 | 40.0 | 3.02e-01 | 88.7% | 99.7% |