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membrane_protein_S4

Euk-Vir

Saimiriine_betaherpesvirus_4

membrane_protein_S4__YP_004940180__Saimiriine_betaherpesvirus_4__1535247

Identity

Accession:
YP_004940180 ↗
Protein ID:
membrane_protein_S4
Kingdom:
euk

Quality

75.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 109-201
PDB
D2 high residues 212-274
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fp2A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 3.32e-01 73.0% 74.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None 0.87 64.0 3.73e-01 77.8% 10.9%
D3 medium residues 51-98
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kjmA02 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.87 59.0 5.65e-01 70.8% 63.6%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 56.0 5.30e-01 70.8% 61.4%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.77 68.0 6.03e-01 97.9% 86.6%
2ynqB00 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.75 59.0 4.13e-01 85.4% 30.5%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.74 64.0 5.30e-01 100.0% 74.7%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.73 61.0 5.32e-01 100.0% 63.3%
3fblA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 61.0 5.20e-01 100.0% 64.6%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.71 47.0 4.35e-01 70.8% 59.1%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.71 61.0 4.08e-01 100.0% 32.3%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.70 49.0 4.28e-01 75.0% 72.7%
4uiqB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.69 60.0 4.23e-01 100.0% 79.7%
5tkyA05 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 49.0 4.12e-01 77.1% 44.8%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 56.0 5.36e-01 100.0% 79.7%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 55.0 4.48e-01 100.0% 80.2%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.67 55.0 4.73e-01 100.0% 71.8%
2guzB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.67 54.0 4.93e-01 91.7% 75.4%
1kpsB00 1.25.40.200 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain 0.66 55.0 3.94e-01 100.0% 32.1%
4hteA03 1.10.167.30 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.66 52.0 4.49e-01 95.8% 55.0%
4rg8A04 1.10.287.1240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 44.0 4.13e-01 72.9% 58.1%
3zheB02 1.20.190.60 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.64 52.0 3.64e-01 95.8% 39.2%
2wauA01 1.20.1310.20 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain 0.64 50.0 3.75e-01 100.0% 64.5%
2gomA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.64 51.0 4.91e-01 100.0% 80.3%
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.64 52.0 4.24e-01 100.0% 51.0%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.63 42.0 3.61e-01 70.8% 39.5%
2a3vB01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.63 54.0 4.40e-01 100.0% 51.1%
2qorA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 49.0 3.61e-01 87.5% 66.2%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 50.0 4.15e-01 100.0% 92.2%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.63 51.0 3.48e-01 95.8% 60.2%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.62 44.0 3.81e-01 77.1% 58.7%
4finB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 45.0 2.89e-01 100.0% 14.7%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 46.0 3.46e-01 100.0% 28.8%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 49.0 3.65e-01 100.0% 72.4%
1z8fA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 48.0 3.67e-01 89.6% 66.1%
3ejbH02 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.61 48.0 3.18e-01 100.0% 72.5%
7odyC01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.61 42.0 3.44e-01 72.9% 72.8%
3eujB00 1.10.225.40 Mainly Alpha › Orthogonal Bundle › NK-Lysin › MukF, C-terminal domain 0.61 48.0 4.14e-01 100.0% 55.6%
3w1oA00 3.40.1760.20 Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical protein yfbM fold › 0.61 52.0 4.00e-01 100.0% 47.0%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.60 48.0 3.88e-01 100.0% 69.1%
4efcA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.60 50.0 4.61e-01 91.7% 88.5%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 48.0 3.65e-01 100.0% 82.0%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.59 41.0 3.94e-01 77.1% 62.3%
2ffjA01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.59 39.0 3.85e-01 70.8% 64.3%
1cf7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 49.0 4.24e-01 100.0% 64.6%
6t4hA03 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.58 45.0 3.14e-01 89.6% 65.1%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.58 44.0 3.60e-01 97.9% 67.8%
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.57 42.0 3.65e-01 83.3% 55.7%
3frqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 46.0 3.21e-01 100.0% 37.5%
3kheA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.56 41.0 3.32e-01 83.3% 41.1%
2co9A00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.53 40.0 3.24e-01 85.4% 44.1%
3f2bA07 6.10.140.1510 Special › Helix non-globular › Helix Hairpins › 0.53 38.0 3.26e-01 81.2% 95.3%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 39.0 3.34e-01 100.0% 65.1%
2oyyA00 6.10.80.10 Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) 0.50 35.0 3.25e-01 77.1% 64.8%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3577145 4030.1.1.0 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.93 79.0 7.52e-01 100.0% 80.0%
3353608 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.90 76.0 4.77e-01 100.0% 20.0%
3582573 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.89 61.0 4.47e-01 70.8% 31.8%
4999600 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.85 75.0 4.88e-01 100.0% 40.0%
4009690 7523.1.1.25 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Phosphonate-bd 0.81 59.0 3.83e-01 77.1% 52.8%
3394861 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.78 68.0 4.49e-01 97.9% 82.1%
3788524 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 67.0 3.73e-01 100.0% 9.6%
3889971 109.4.1.1643 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 0.77 67.0 5.16e-01 100.0% 50.9%
3773905 604.3.1.33 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › RSLD_CPSF6 0.77 67.0 5.82e-01 100.0% 74.7%
3598425 195.1.1.0 alpha complex topology › NusB-like › NusB-like › NusB-like 0.76 67.0 4.59e-01 100.0% 30.6%
4179875 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.76 64.0 4.53e-01 93.8% 31.0%
3924801 109.4.1.1643 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 0.74 62.0 5.09e-01 100.0% 61.1%
3731551 106.1.1.7 alpha arrays › Globin-like › Globin-like › Globin-like › Protoglobin 0.74 66.0 4.33e-01 100.0% 68.5%
3717682 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 60.0 4.02e-01 100.0% 24.0%
3719996 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 61.0 4.78e-01 100.0% 45.7%
3612815 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.71 61.0 4.60e-01 100.0% 40.0%
4024559 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.70 60.0 3.98e-01 93.8% 29.2%
3822956 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 60.0 5.47e-01 100.0% 75.4%
3332657 109.4.1.1269 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.69 57.0 4.53e-01 100.0% 44.5%
3839909 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.67 61.0 3.74e-01 100.0% 19.4%
3877844 529.1.1.2 few secondary structure elements › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › BSMAP 0.65 56.0 4.62e-01 100.0% 56.7%
3285411 1016.1.1.0 alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 0.65 53.0 3.83e-01 95.8% 100.0%
5001714 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.65 61.0 3.47e-01 100.0% 11.7%
3497745 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.65 54.0 3.39e-01 95.8% 48.6%
3566807 616.1.1.0 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.64 53.0 5.01e-01 97.9% 76.7%
3578718 101.1.6.0 alpha arrays › HTH › HTH › TrpR 0.64 52.0 4.28e-01 95.8% 48.4%
5060248 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.64 43.0 3.86e-01 77.1% 48.6%
4970797 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 56.0 3.28e-01 100.0% 13.9%
4661498 109.26.1.1 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.61 49.0 3.69e-01 100.0% 33.1%
5026703 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.61 55.0 3.22e-01 100.0% 13.2%
5053823 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.61 53.0 3.12e-01 97.9% 13.5%
3361550 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.60 45.0 3.17e-01 81.2% 30.3%
3208683 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 50.0 5.01e-01 100.0% 96.0%
3544328 3860.1.1.177 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › GRIP, Rab_bind 0.59 49.0 3.66e-01 100.0% 35.4%
3297319 611.3.1.1 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.59 48.0 4.01e-01 100.0% 53.7%
4046570 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.56 39.0 3.68e-01 75.0% 68.3%
5071383 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.56 48.0 3.17e-01 100.0% 30.4%
4983598 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 45.0 4.17e-01 100.0% 84.6%
3282342 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 41.0 2.80e-01 100.0% 85.0%