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membrane_protein_US12C
Euk-VirCercopithecine_betaherpesvirus_5
membrane_protein_US12C__YP_004936124__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936124 ↗
- Protein ID:
- membrane_protein_US12C
- Kingdom:
- euk
Quality
80.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 57-223
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6gyhA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.76 | 61.0 | 5.47e-01 | 83.2% | 99.1% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 52.0 | 4.70e-01 | 85.0% | 99.5% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 48.0 | 4.05e-01 | 80.8% | 96.4% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.59 | 48.0 | 3.88e-01 | 84.4% | 94.6% |
| 1yfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.59 | 46.0 | 3.98e-01 | 82.6% | 92.2% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.57 | 35.0 | 3.96e-01 | 88.0% | 79.8% |
| 5dz2A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 46.0 | 3.74e-01 | 86.2% | 92.9% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.57 | 29.0 | 3.97e-01 | 91.0% | 98.8% |
| 1dofA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 44.0 | 3.92e-01 | 82.6% | 94.3% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 39.0 | 4.32e-01 | 95.8% | 89.3% |
| 5xnyA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 44.0 | 3.90e-01 | 82.6% | 94.7% |
| 1q5nA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 44.0 | 3.89e-01 | 82.6% | 94.7% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 34.0 | 4.14e-01 | 89.2% | 93.6% |
| 7dfeA01 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.55 | 33.0 | 3.67e-01 | 70.1% | 74.8% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 34.0 | 4.16e-01 | 88.0% | 94.5% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 37.0 | 4.32e-01 | 95.2% | 95.8% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 42.0 | 3.51e-01 | 80.8% | 85.2% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.54 | 38.0 | 4.17e-01 | 95.8% | 89.1% |
| 3edvA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 32.0 | 3.08e-01 | 86.2% | 53.0% |
| 3hwcA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 34.0 | 3.13e-01 | 80.2% | 50.0% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.52 | 37.0 | 3.40e-01 | 70.7% | 79.9% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 41.0 | 3.43e-01 | 82.6% | 85.2% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.40e-01 | 82.0% | 85.1% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.50 | 32.0 | 3.74e-01 | 88.0% | 93.6% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.50 | 32.0 | 3.81e-01 | 89.8% | 93.9% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3262699 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.73 | 57.0 | 4.68e-01 | 82.0% | 87.8% |
| 3343869 | 5001.1.1.122 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 | 0.72 | 58.0 | 4.66e-01 | 83.2% | 91.9% |
| 3397602 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.71 | 64.0 | 5.68e-01 | 94.0% | 80.4% |
| 3394147 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.71 | 63.0 | 5.66e-01 | 94.0% | 80.4% |
| 3486791 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.70 | 62.0 | 6.23e-01 | 92.8% | 100.0% |
| 3411573 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.70 | 64.0 | 5.64e-01 | 95.8% | 78.2% |
| 3415929 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.70 | 64.0 | 5.77e-01 | 95.8% | 81.4% |
| 3471323 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.69 | 62.0 | 5.62e-01 | 94.0% | 81.4% |
| 3471382 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.69 | 61.0 | 5.47e-01 | 93.4% | 80.0% |
| 3478731 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.69 | 62.0 | 6.02e-01 | 95.8% | 93.5% |
| 3473124 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.68 | 60.0 | 5.40e-01 | 94.0% | 76.9% |
| 3989144 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.67 | 61.0 | 5.47e-01 | 94.6% | 79.5% |
| 3213060 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.67 | 54.0 | 4.33e-01 | 85.0% | 88.8% |
| 3270603 | 5001.1.1.81 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom | 0.67 | 54.0 | 4.59e-01 | 84.4% | 97.7% |
| 3216054 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.67 | 53.0 | 4.35e-01 | 83.2% | 96.0% |
| 3484915 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.67 | 62.0 | 5.33e-01 | 99.4% | 72.5% |
| 3213897 | 5001.1.1.45 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra | 0.66 | 53.0 | 4.27e-01 | 83.8% | 90.9% |
| 4519670 | 5045.1.1.3 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › V_ATPase_I | 0.66 | 50.0 | 4.24e-01 | 77.2% | 90.6% |
| 3286925 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.64 | 40.0 | 4.68e-01 | 88.0% | 86.7% |
| 4937038 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.63 | 56.0 | 5.17e-01 | 94.0% | 84.3% |
| 5032452 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.63 | 50.0 | 4.84e-01 | 83.2% | 94.1% |
| 3240061 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 48.0 | 3.70e-01 | 82.0% | 75.8% |
| 3679787 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.61 | 25.0 | 2.15e-01 | 96.4% | 23.0% |
| 3565644 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 49.0 | 3.97e-01 | 88.6% | 88.6% |
| 3489998 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 50.0 | 3.87e-01 | 91.0% | 85.5% |
| 5047060 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.57 | 44.0 | 3.96e-01 | 79.6% | 97.4% |
| 3937340 | 150.1.1.105 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › ATG2_CAD | 0.57 | 38.0 | 3.71e-01 | 98.2% | 61.7% |
| 4426096 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 40.0 | 4.52e-01 | 82.0% | 92.3% |
| 4959876 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.57 | 42.0 | 3.50e-01 | 76.6% | 96.9% |
| 3222649 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.55 | 44.0 | 3.50e-01 | 85.6% | 91.0% |
| 5081836 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 41.0 | 3.95e-01 | 79.6% | 86.5% |
| 3591699 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.54 | 29.0 | 3.62e-01 | 91.0% | 85.0% |
| 3560590 | 3755.3.1.142 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C | 0.53 | 37.0 | 3.96e-01 | 71.9% | 88.0% |
| 3930842 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.52 | 42.0 | 3.39e-01 | 82.0% | 86.4% |
| 3875091 | 150.1.1.24 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin | 0.52 | 39.0 | 3.41e-01 | 76.6% | 96.7% |
| 3367916 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.51 | 41.0 | 4.23e-01 | 99.4% | 90.3% |
| 3719613 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.51 | 39.0 | 3.47e-01 | 78.4% | 84.0% |
| 3709676 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.50 | 38.0 | 3.23e-01 | 94.6% | 47.6% |
D2
medium
residues 1-56
Domain cluster:
representative