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membrane_protein_US12D
Euk-VirCercopithecine_betaherpesvirus_5
membrane_protein_US12D__YP_004936125__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936125 ↗
- Protein ID:
- membrane_protein_US12D
- Kingdom:
- euk
Quality
79.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 47-101
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 67.0 | 5.35e-01 | 100.0% | 60.6% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 65.0 | 5.74e-01 | 98.2% | 82.7% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.74 | 63.0 | 5.55e-01 | 96.4% | 84.1% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 63.0 | 5.39e-01 | 100.0% | 76.1% |
| 3gnlB02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 62.0 | 5.87e-01 | 100.0% | 82.4% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 60.0 | 5.57e-01 | 96.4% | 75.0% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 61.0 | 5.59e-01 | 98.2% | 73.3% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 61.0 | 5.13e-01 | 100.0% | 71.4% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.71 | 56.0 | 5.83e-01 | 90.9% | 96.0% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 60.0 | 5.06e-01 | 98.2% | 86.5% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.70 | 59.0 | 5.71e-01 | 96.4% | 87.5% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 60.0 | 5.90e-01 | 98.2% | 94.9% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 60.0 | 4.63e-01 | 100.0% | 55.5% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.70 | 59.0 | 4.37e-01 | 98.2% | 98.0% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.69 | 59.0 | 4.80e-01 | 100.0% | 70.9% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 58.0 | 5.52e-01 | 98.2% | 82.1% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 56.0 | 5.45e-01 | 92.7% | 85.5% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 59.0 | 4.83e-01 | 100.0% | 65.4% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 57.0 | 5.67e-01 | 98.2% | 91.4% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 57.0 | 4.81e-01 | 96.4% | 56.1% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 55.0 | 4.43e-01 | 98.2% | 44.4% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.68 | 59.0 | 5.12e-01 | 98.2% | 64.7% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 57.0 | 5.60e-01 | 98.2% | 91.7% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.68 | 54.0 | 4.77e-01 | 96.4% | 58.6% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 55.0 | 5.18e-01 | 98.2% | 94.5% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.68 | 57.0 | 5.39e-01 | 96.4% | 80.6% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.68 | 57.0 | 5.03e-01 | 94.5% | 67.9% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 56.0 | 4.34e-01 | 100.0% | 74.5% |
| 5u1xA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.67 | 46.0 | 4.96e-01 | 76.4% | 87.0% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 56.0 | 5.11e-01 | 96.4% | 72.0% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.67 | 56.0 | 4.52e-01 | 94.5% | 50.9% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.67 | 55.0 | 5.14e-01 | 96.4% | 77.5% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.67 | 52.0 | 4.83e-01 | 87.3% | 67.6% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.66 | 55.0 | 4.87e-01 | 96.4% | 67.1% |
| 4v3iA00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.66 | 53.0 | 3.84e-01 | 87.3% | 35.3% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.66 | 53.0 | 5.31e-01 | 96.4% | 100.0% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.65 | 55.0 | 4.86e-01 | 98.2% | 68.2% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 56.0 | 5.31e-01 | 100.0% | 98.5% |
| 3gb8A01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.65 | 54.0 | 3.15e-01 | 100.0% | 10.8% |
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 54.0 | 4.76e-01 | 96.4% | 66.3% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.64 | 53.0 | 4.66e-01 | 100.0% | 63.3% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.64 | 52.0 | 3.72e-01 | 96.4% | 30.6% |
| 1bf3A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.63 | 46.0 | 3.09e-01 | 81.8% | 24.6% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 51.0 | 4.24e-01 | 94.5% | 50.9% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 51.0 | 5.04e-01 | 98.2% | 94.8% |
| 8d3mA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.62 | 49.0 | 3.36e-01 | 98.2% | 22.9% |
| 4o8sA02 | 1.20.58.1790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain | 0.61 | 46.0 | 3.82e-01 | 85.5% | 57.0% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 47.0 | 3.94e-01 | 96.4% | 47.8% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.58 | 45.0 | 4.53e-01 | 89.1% | 100.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 46.0 | 4.43e-01 | 96.4% | 84.6% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3415929 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.79 | 69.0 | 4.61e-01 | 100.0% | 26.5% |
| 3691039 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 65.0 | 5.70e-01 | 94.5% | 65.0% |
| 3397602 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.76 | 66.0 | 4.39e-01 | 100.0% | 24.9% |
| 4329615 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 65.0 | 6.00e-01 | 96.4% | 87.1% |
| 3968516 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 62.0 | 5.64e-01 | 96.4% | 68.0% |
| 4033272 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.75 | 64.0 | 4.97e-01 | 96.4% | 48.3% |
| 3540947 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.74 | 64.0 | 4.31e-01 | 100.0% | 29.1% |
| 4927007 | 605.1.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim | 0.74 | 61.0 | 6.11e-01 | 96.4% | 92.7% |
| 3487803 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.74 | 64.0 | 4.24e-01 | 100.0% | 25.4% |
| 4960850 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.73 | 62.0 | 6.04e-01 | 96.4% | 86.7% |
| 3233589 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 61.0 | 5.56e-01 | 96.4% | 84.0% |
| 4950709 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 61.0 | 5.79e-01 | 96.4% | 100.0% |
| 3546135 | 10.12.1.108 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › POPDC1-3 | 0.71 | 58.0 | 5.26e-01 | 90.9% | 69.3% |
| 3375600 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.70 | 59.0 | 5.09e-01 | 96.4% | 61.1% |
| 3815113 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 55.0 | 5.02e-01 | 87.3% | 64.0% |
| 4258322 | 5086.1.1.189 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB | 0.69 | 58.0 | 5.45e-01 | 98.2% | 78.6% |
| 3992872 | 192.17.1.17 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › Got1 | 0.69 | 55.0 | 5.29e-01 | 89.1% | 76.9% |
| 3974231 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.69 | 57.0 | 5.40e-01 | 98.2% | 78.6% |
| 3736053 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 55.0 | 4.76e-01 | 94.5% | 54.7% |
| 3598908 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.69 | 54.0 | 5.24e-01 | 85.5% | 78.3% |
| 3763471 | 2004.1.1.152 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › KAP_NTPase | 0.67 | 53.0 | 3.33e-01 | 92.7% | 21.2% |
| 3928911 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.67 | 57.0 | 5.29e-01 | 96.4% | 87.1% |
| 3663052 | 5043.1.1.13 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Sugar_tr | 0.67 | 51.0 | 4.82e-01 | 87.3% | 84.3% |
| 3477962 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.66 | 58.0 | 4.96e-01 | 100.0% | 68.9% |
| 3926694 | 3324.1.1.0 ↗ | extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases | 0.65 | 56.0 | 4.12e-01 | 96.4% | 88.3% |
| 5018187 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.61 | 50.0 | 4.82e-01 | 98.2% | 80.0% |
| 3289420 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.61 | 49.0 | 2.89e-01 | 100.0% | 9.8% |
| 5028289 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.61 | 48.0 | 3.11e-01 | 96.4% | 19.0% |
| 4857875 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.60 | 49.0 | 4.41e-01 | 98.2% | 64.3% |
| 3962167 | 3718.1.1.0 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT | 0.54 | 37.0 | 3.55e-01 | 74.5% | 61.4% |
D2
medium
residues 102-245