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membrane_protein_US12
Euk-VirPanine_betaherpesvirus_2
membrane_protein_US12__NP_612785__Panine_betaherpesvirus_2__188763
Identity
- Accession:
- NP_612785 ↗
- Protein ID:
- membrane_protein_US12
- Kingdom:
- euk
Quality
78.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Panine_betaherpesvirus_2
TaxID: 188763
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 69-177
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2e9xD01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 38.0 | 3.54e-01 | 88.1% | 43.1% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.63 | 55.0 | 5.14e-01 | 94.5% | 90.2% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 49.0 | 4.32e-01 | 86.2% | 87.3% |
| 6z01B03 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.62 | 43.0 | 3.85e-01 | 71.6% | 52.6% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 50.0 | 4.30e-01 | 89.0% | 82.0% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 52.0 | 4.67e-01 | 91.7% | 68.9% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.61 | 46.0 | 5.08e-01 | 89.0% | 100.0% |
| 3vkgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.61 | 43.0 | 3.86e-01 | 74.3% | 55.6% |
| 6wbvA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 53.0 | 3.59e-01 | 100.0% | 64.0% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.59 | 51.0 | 4.24e-01 | 94.5% | 63.4% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 36.0 | 3.79e-01 | 100.0% | 66.3% |
| 2hqcA01 | 1.20.1640.10 | Mainly Alpha › Up-down Bundle › Multidrug efflux transporter AcrB transmembrane fold › Multidrug efflux transporter AcrB transmembrane domain | 0.59 | 43.0 | 3.58e-01 | 78.9% | 42.1% |
| 4gc0A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 51.0 | 3.98e-01 | 97.2% | 64.6% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 42.0 | 4.02e-01 | 78.0% | 86.2% |
| 8g59R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 42.0 | 3.18e-01 | 77.1% | 98.9% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.56 | 43.0 | 4.03e-01 | 80.7% | 100.0% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 42.0 | 2.79e-01 | 78.9% | 54.7% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 42.0 | 2.96e-01 | 79.8% | 62.5% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.54 | 38.0 | 2.68e-01 | 70.6% | 99.7% |
| 2bl7A00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.53 | 35.0 | 4.05e-01 | 88.1% | 93.7% |
| 2c2aA01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.52 | 40.0 | 4.35e-01 | 99.1% | 95.6% |
| 3v5uA02 | 1.20.1420.30 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › NCX, central ion-binding region | 0.52 | 42.0 | 3.48e-01 | 91.7% | 66.1% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 40.0 | 3.31e-01 | 83.5% | 83.5% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.51 | 42.0 | 4.10e-01 | 89.0% | 84.6% |
| 3crmA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.51 | 32.0 | 3.64e-01 | 85.3% | 83.3% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3743077 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 47.0 | 4.48e-01 | 70.6% | 82.4% |
| 3991191 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.66 | 53.0 | 4.83e-01 | 88.1% | 88.0% |
| 3637538 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.66 | 55.0 | 4.60e-01 | 91.7% | 75.3% |
| 3511483 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.65 | 55.0 | 4.90e-01 | 91.7% | 71.0% |
| 3938596 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 54.0 | 4.92e-01 | 91.7% | 75.3% |
| 3787128 | 109.4.1.654 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFB6 | 0.65 | 50.0 | 3.98e-01 | 83.5% | 74.8% |
| 3205832 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.64 | 56.0 | 4.30e-01 | 95.4% | 53.9% |
| 3736715 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 55.0 | 4.70e-01 | 94.5% | 81.1% |
| 3446922 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.64 | 54.0 | 4.22e-01 | 94.5% | 55.5% |
| 3733441 | 5050.1.1.55 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr, MFS_1 | 0.62 | 54.0 | 3.67e-01 | 97.2% | 77.7% |
| 5027495 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.62 | 46.0 | 5.07e-01 | 80.7% | 98.8% |
| 3490246 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 53.0 | 4.38e-01 | 95.4% | 64.5% |
| 3206380 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.61 | 51.0 | 4.42e-01 | 91.7% | 73.1% |
| 4643744 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.60 | 45.0 | 4.89e-01 | 80.7% | 96.7% |
| 3433766 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.60 | 51.0 | 4.07e-01 | 94.5% | 53.3% |
| 3268437 | 622.4.1.60 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › zf-RING_2 | 0.60 | 48.0 | 3.77e-01 | 86.2% | 85.7% |
| 3264612 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 49.0 | 4.20e-01 | 90.8% | 67.8% |
| 4306757 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.58 | 44.0 | 4.51e-01 | 80.7% | 98.1% |
| 4944665 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.57 | 51.0 | 3.58e-01 | 100.0% | 93.4% |
| 3994884 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 44.0 | 3.25e-01 | 85.3% | 89.4% |
| 3802402 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.56 | 44.0 | 3.92e-01 | 83.5% | 98.1% |
| 3222373 | 605.4.1.18 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 | 0.56 | 40.0 | 4.47e-01 | 78.9% | 96.5% |
| 3581398 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 43.0 | 3.97e-01 | 80.7% | 85.2% |
| 3634706 | 601.1.2.94 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › VBS_C3G9 | 0.53 | 40.0 | 4.33e-01 | 78.0% | 100.0% |
| 4185405 | 589.1.2.1 ↗ | alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › TF C-terminus (Pfam 05698) › Trigger_C | 0.52 | 37.0 | 3.21e-01 | 74.3% | 87.9% |
| 4675311 | 632.19.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › TMEM208_SND2 | 0.51 | 39.0 | 3.86e-01 | 81.7% | 73.3% |
| 3332048 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.51 | 40.0 | 4.04e-01 | 83.5% | 93.6% |
| 4939465 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.51 | 37.0 | 3.70e-01 | 76.1% | 73.9% |
| 3922156 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.51 | 36.0 | 3.19e-01 | 73.4% | 65.2% |
| 5058654 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.50 | 44.0 | 3.94e-01 | 97.2% | 77.4% |
D2
medium
residues 178-286
Domain cluster:
rep: membrane_protein_US17__YP_004936127__Cercopithecine_betaherpesvirus_5__50292__D117-239
CATH (51)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.78 | 55.0 | 5.46e-01 | 72.5% | 97.4% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.75 | 52.0 | 5.18e-01 | 70.6% | 87.5% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 56.0 | 4.73e-01 | 78.9% | 79.2% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.71 | 63.0 | 5.49e-01 | 94.5% | 98.1% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 52.0 | 5.30e-01 | 78.0% | 93.4% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.70 | 56.0 | 5.52e-01 | 91.7% | 79.8% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 63.0 | 5.03e-01 | 100.0% | 86.8% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.68 | 47.0 | 3.95e-01 | 70.6% | 69.0% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 37.0 | 3.98e-01 | 70.6% | 61.3% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.68 | 58.0 | 4.81e-01 | 92.7% | 92.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.68 | 53.0 | 5.19e-01 | 95.4% | 77.6% |
| 1qgtB00 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.67 | 47.0 | 4.28e-01 | 73.4% | 55.2% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.67 | 46.0 | 3.86e-01 | 70.6% | 68.9% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.66 | 59.0 | 4.64e-01 | 99.1% | 49.3% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 57.0 | 4.42e-01 | 96.3% | 77.9% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.66 | 58.0 | 4.83e-01 | 100.0% | 93.0% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 58.0 | 4.85e-01 | 98.2% | 87.8% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 58.0 | 4.69e-01 | 98.2% | 83.7% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 56.0 | 4.38e-01 | 94.5% | 83.5% |
| 1kxpD02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.65 | 46.0 | 5.01e-01 | 99.1% | 92.0% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 57.0 | 4.25e-01 | 98.2% | 78.5% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.64 | 45.0 | 4.40e-01 | 96.3% | 66.7% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 53.0 | 4.34e-01 | 97.2% | 48.8% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.64 | 51.0 | 3.95e-01 | 85.3% | 72.9% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.63 | 57.0 | 5.09e-01 | 99.1% | 76.5% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 54.0 | 5.23e-01 | 98.2% | 85.1% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 53.0 | 4.91e-01 | 99.1% | 71.3% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.63 | 48.0 | 4.99e-01 | 89.0% | 86.4% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.62 | 44.0 | 4.93e-01 | 99.1% | 92.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 55.0 | 5.26e-01 | 100.0% | 82.8% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 54.0 | 5.28e-01 | 98.2% | 88.2% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 55.0 | 4.13e-01 | 98.2% | 76.4% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.62 | 56.0 | 4.60e-01 | 99.1% | 64.3% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.62 | 57.0 | 4.96e-01 | 100.0% | 89.6% |
| 3vkgB06 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.62 | 56.0 | 4.28e-01 | 98.2% | 69.4% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 56.0 | 4.29e-01 | 100.0% | 79.2% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 55.0 | 4.96e-01 | 99.1% | 71.9% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 53.0 | 5.52e-01 | 98.2% | 98.1% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 54.0 | 4.05e-01 | 100.0% | 68.6% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.60 | 51.0 | 4.07e-01 | 90.8% | 87.3% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 53.0 | 4.05e-01 | 100.0% | 66.8% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.60 | 52.0 | 5.31e-01 | 100.0% | 93.5% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 53.0 | 4.31e-01 | 98.2% | 82.5% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.59 | 53.0 | 4.09e-01 | 99.1% | 78.4% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.58 | 51.0 | 4.61e-01 | 99.1% | 74.2% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 52.0 | 4.97e-01 | 99.1% | 87.9% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.57 | 51.0 | 4.73e-01 | 99.1% | 87.9% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.55 | 48.0 | 4.41e-01 | 100.0% | 84.9% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.53 | 39.0 | 4.18e-01 | 84.4% | 88.5% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.52 | 44.0 | 3.90e-01 | 95.4% | 91.4% |
| 6a95A01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.50 | 44.0 | 4.23e-01 | 100.0% | 83.3% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3899680 | 3755.3.1.345 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Hobbit | 0.78 | 56.0 | 5.18e-01 | 73.4% | 76.3% |
| 4991538 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.78 | 60.0 | 4.98e-01 | 79.8% | 86.6% |
| 3231462 | 632.8.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C | 0.78 | 58.0 | 6.29e-01 | 77.1% | 98.9% |
| 3479389 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.77 | 69.0 | 5.70e-01 | 95.4% | 90.8% |
| 3717920 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.77 | 60.0 | 5.24e-01 | 100.0% | 56.8% |
| 3472905 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.77 | 69.0 | 5.58e-01 | 95.4% | 86.2% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.75 | 56.0 | 6.01e-01 | 78.0% | 98.9% |
| 3471617 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.74 | 66.0 | 6.17e-01 | 100.0% | 78.5% |
| 3216129 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.74 | 66.0 | 6.33e-01 | 97.2% | 83.2% |
| 4949106 | 2007.1.3.74 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › MetOD2 | 0.73 | 61.0 | 4.96e-01 | 90.8% | 50.7% |
| 3480861 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.71 | 61.0 | 4.55e-01 | 90.8% | 84.3% |
| 4990428 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.71 | 63.0 | 5.06e-01 | 100.0% | 88.6% |
| 3170736 | 601.1.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GCIP_N | 0.70 | 62.0 | 5.31e-01 | 93.6% | 97.0% |
| 4008609 | 1203.1.2.7 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR | 0.70 | 57.0 | 5.30e-01 | 89.0% | 69.3% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 52.0 | 5.03e-01 | 96.3% | 69.6% |
| 4010267 | 192.8.1.131 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › GNVR | 0.69 | 57.0 | 5.36e-01 | 88.1% | 73.8% |
| 4968767 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.69 | 62.0 | 5.07e-01 | 100.0% | 89.8% |
| 3419627 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.69 | 62.0 | 5.58e-01 | 100.0% | 80.7% |
| 3946576 | 5086.1.1.66 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR | 0.69 | 57.0 | 5.30e-01 | 89.0% | 71.9% |
| 3623648 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.69 | 60.0 | 5.16e-01 | 94.5% | 82.4% |
| 3230496 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.68 | 50.0 | 5.60e-01 | 99.1% | 98.8% |
| 3931313 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.68 | 61.0 | 5.28e-01 | 98.2% | 64.2% |
| 3613860 | 601.1.2.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17 | 0.67 | 54.0 | 4.94e-01 | 98.2% | 66.4% |
| 3489411 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.67 | 58.0 | 5.14e-01 | 98.2% | 74.5% |
| 4017167 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.66 | 61.0 | 4.48e-01 | 100.0% | 63.6% |
| 4283760 | 1203.1.2.7 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR | 0.66 | 54.0 | 5.02e-01 | 89.0% | 69.3% |
| 5009681 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.66 | 61.0 | 5.60e-01 | 100.0% | 80.0% |
| 3972755 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.66 | 53.0 | 5.18e-01 | 86.2% | 85.6% |
| 3300142 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 59.0 | 5.32e-01 | 100.0% | 91.3% |
| 4028241 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 59.0 | 5.20e-01 | 98.2% | 91.6% |
| 3495538 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.65 | 57.0 | 4.97e-01 | 98.2% | 64.4% |
| 5026394 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.65 | 54.0 | 5.30e-01 | 100.0% | 83.5% |
| 3801633 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.65 | 58.0 | 5.17e-01 | 99.1% | 89.0% |
| 4683248 | 5086.1.1.66 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR | 0.64 | 53.0 | 4.87e-01 | 89.0% | 69.3% |
| 3990526 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.64 | 57.0 | 4.50e-01 | 99.1% | 68.3% |
| 3886622 | 192.29.1.57 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ninjurin | 0.64 | 58.0 | 5.42e-01 | 99.1% | 100.0% |
| 3174418 | 133.1.1.7 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › PF28625 | 0.64 | 52.0 | 4.50e-01 | 99.1% | 56.5% |
| 3649632 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.63 | 58.0 | 5.31e-01 | 100.0% | 83.6% |
| 4944388 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.63 | 55.0 | 4.73e-01 | 98.2% | 75.0% |
| 3358694 | 192.29.1.101 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N | 0.63 | 56.0 | 5.48e-01 | 95.4% | 90.8% |
| 3453285 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.63 | 53.0 | 4.96e-01 | 99.1% | 74.1% |
| 5074351 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.63 | 49.0 | 4.84e-01 | 98.2% | 78.8% |
| 3582431 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.62 | 51.0 | 4.55e-01 | 99.1% | 63.3% |
| 3862608 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 55.0 | 5.52e-01 | 98.2% | 94.5% |
| 3785883 | 4177.1.1.97 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147 | 0.62 | 54.0 | 4.62e-01 | 98.2% | 88.1% |
| 3216054 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.62 | 56.0 | 4.10e-01 | 100.0% | 63.7% |
| 3910532 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.62 | 55.0 | 5.26e-01 | 98.2% | 88.8% |
| 3239453 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.62 | 55.0 | 5.19e-01 | 100.0% | 83.7% |
| 3596738 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.62 | 50.0 | 4.55e-01 | 100.0% | 64.8% |
| 3280119 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.62 | 52.0 | 4.48e-01 | 93.6% | 92.2% |
| 3227811 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 55.0 | 4.89e-01 | 98.2% | 67.7% |
| 3254670 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.62 | 55.0 | 4.39e-01 | 100.0% | 79.6% |
| 3213680 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.62 | 55.0 | 4.04e-01 | 100.0% | 61.7% |
| 5029100 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.61 | 55.0 | 4.88e-01 | 100.0% | 75.5% |
| 3871010 | 611.8.1.1 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne | 0.60 | 55.0 | 4.67e-01 | 100.0% | 80.0% |
| 3478793 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.60 | 53.0 | 4.33e-01 | 97.2% | 81.0% |
| 5054107 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.59 | 49.0 | 3.79e-01 | 90.8% | 78.0% |
| 4059733 | 4177.1.1.66 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › ATG17_like | 0.59 | 53.0 | 4.17e-01 | 98.2% | 85.0% |
| 3926303 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.58 | 52.0 | 4.58e-01 | 100.0% | 78.8% |
| 4190833 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.57 | 51.0 | 5.00e-01 | 98.2% | 90.0% |
| 3207391 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.57 | 44.0 | 4.09e-01 | 96.3% | 62.8% |
| 3752923 | 601.4.1.42 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMEM138 | 0.57 | 49.0 | 4.48e-01 | 98.2% | 77.4% |
| 4947640 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.57 | 51.0 | 3.79e-01 | 95.4% | 71.0% |