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membrane_protein_US14
Euk-VirCynomolgus_macaque_cytomegalovirus_strain_Ottawa
membrane_protein_US14__YP_004933971__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969
Identity
- Accession:
- YP_004933971 ↗
- Protein ID:
- membrane_protein_US14
- Kingdom:
- euk
Quality
76.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cynomolgus_macaque_cytomegalovirus_strain_Ottawa
TaxID: 944969
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 9-105
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6wbvA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.73 | 62.0 | 4.01e-01 | 91.8% | 23.1% |
| 2cfqA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.73 | 56.0 | 4.32e-01 | 91.8% | 37.3% |
| 4pypA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 59.0 | 3.79e-01 | 93.8% | 77.0% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.67 | 53.0 | 4.38e-01 | 91.8% | 46.7% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.66 | 39.0 | 3.30e-01 | 100.0% | 36.0% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.65 | 48.0 | 5.05e-01 | 80.4% | 87.4% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.64 | 53.0 | 4.09e-01 | 91.8% | 41.9% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.63 | 50.0 | 4.05e-01 | 94.8% | 43.3% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.63 | 49.0 | 3.80e-01 | 89.7% | 37.6% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.61 | 46.0 | 3.09e-01 | 79.4% | 94.4% |
| 4zudA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 45.0 | 3.32e-01 | 77.3% | 96.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 37.0 | 3.42e-01 | 90.7% | 46.2% |
| 2rgnB01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.59 | 42.0 | 3.35e-01 | 74.2% | 78.9% |
| 2kbwA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.59 | 53.0 | 4.56e-01 | 100.0% | 76.5% |
| 4mt0A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.58 | 48.0 | 3.22e-01 | 88.7% | 52.7% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.58 | 47.0 | 3.05e-01 | 86.6% | 77.1% |
| 2jbyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.57 | 48.0 | 4.35e-01 | 89.7% | 77.2% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 41.0 | 3.80e-01 | 81.4% | 87.7% |
| 5u4nA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 42.0 | 2.87e-01 | 83.5% | 85.4% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 43.0 | 3.04e-01 | 88.7% | 62.6% |
| 3wfwA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 45.0 | 3.99e-01 | 100.0% | 65.2% |
| 6okdA03 | 1.20.930.40 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain | 0.53 | 44.0 | 3.89e-01 | 90.7% | 86.3% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 41.0 | 3.84e-01 | 86.6% | 77.5% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 41.0 | 3.07e-01 | 86.6% | 69.7% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3941981 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 57.0 | 4.46e-01 | 88.7% | 39.5% |
| 4222857 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 54.0 | 4.28e-01 | 91.8% | 38.5% |
| 5026179 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 57.0 | 4.56e-01 | 90.7% | 44.9% |
| 3229719 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.71 | 62.0 | 4.62e-01 | 100.0% | 38.0% |
| 5046439 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 56.0 | 4.27e-01 | 91.8% | 37.3% |
| 4590424 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 55.0 | 4.30e-01 | 91.8% | 40.5% |
| 4977940 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 52.0 | 4.12e-01 | 91.8% | 39.0% |
| 3964811 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 57.0 | 4.53e-01 | 91.8% | 47.0% |
| 5037182 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 54.0 | 4.21e-01 | 92.8% | 38.6% |
| 3477962 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.67 | 58.0 | 6.00e-01 | 91.8% | 100.0% |
| 4616546 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.66 | 42.0 | 4.11e-01 | 73.2% | 58.1% |
| 3263522 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.66 | 53.0 | 4.18e-01 | 89.7% | 41.0% |
| 5036274 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.66 | 42.0 | 4.57e-01 | 72.2% | 78.8% |
| 3921752 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.65 | 53.0 | 4.07e-01 | 90.7% | 55.3% |
| 3832320 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.65 | 53.0 | 3.74e-01 | 91.8% | 41.5% |
| 4071531 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.64 | 53.0 | 4.35e-01 | 91.8% | 51.9% |
| 3934477 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.63 | 52.0 | 4.96e-01 | 91.8% | 81.7% |
| 4010333 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 53.0 | 4.08e-01 | 91.8% | 43.2% |
| 3428665 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.63 | 51.0 | 4.28e-01 | 100.0% | 49.4% |
| 5066060 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 52.0 | 4.24e-01 | 92.8% | 55.8% |
| 5050092 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 52.0 | 4.12e-01 | 92.8% | 43.4% |
| 3186813 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 44.0 | 3.93e-01 | 72.2% | 51.9% |
| 4033160 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 52.0 | 4.15e-01 | 92.8% | 53.7% |
| 4946107 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 47.0 | 3.72e-01 | 82.5% | 39.5% |
| 2642997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 48.0 | 3.92e-01 | 85.6% | 74.2% |
| 3204604 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.61 | 38.0 | 4.19e-01 | 73.2% | 80.0% |
| 3534307 | 601.1.1.98 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27524 | 0.61 | 50.0 | 4.37e-01 | 88.7% | 60.0% |
| 3315914 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.61 | 52.0 | 4.60e-01 | 96.9% | 64.1% |
| 3980513 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 47.0 | 3.93e-01 | 85.6% | 75.6% |
| 3387232 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.60 | 42.0 | 4.23e-01 | 73.2% | 86.0% |
| 3957123 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 49.0 | 4.18e-01 | 91.8% | 53.9% |
| 3277855 | 3562.1.1.3 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF6328 | 0.60 | 42.0 | 3.73e-01 | 74.2% | 97.9% |
| 5015635 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 48.0 | 3.98e-01 | 89.7% | 56.7% |
| 4414590 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.59 | 37.0 | 3.04e-01 | 92.8% | 34.4% |
| 4012651 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 46.0 | 3.91e-01 | 94.8% | 49.1% |
| 4082939 | 5001.1.1.45 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra | 0.58 | 43.0 | 3.07e-01 | 78.4% | 65.9% |
| 3926333 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.55 | 47.0 | 3.27e-01 | 100.0% | 44.4% |
| 3340833 | 5086.1.1.109 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Chloroplast_duf | 0.55 | 38.0 | 3.99e-01 | 72.2% | 83.3% |
| 4926779 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.55 | 46.0 | 4.14e-01 | 91.8% | 73.3% |
| 3177704 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.52 | 42.0 | 3.18e-01 | 91.8% | 37.3% |
| 3927027 | 3922.1.1.244 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Otopetrin | 0.50 | 47.0 | 3.32e-01 | 100.0% | 68.0% |
D2
medium
residues 106-218
Domain cluster:
rep: Cy195__YP_009337595__Cynomolgus_cytomegalovirus__1919083__D106-221