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membrane_protein_US15

Euk-Vir

Panine_betaherpesvirus_2

membrane_protein_US15__NP_612788__Panine_betaherpesvirus_2__188763

Identity

Accession:
NP_612788 ↗
Protein ID:
membrane_protein_US15
Kingdom:
euk

Quality

84.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 65-125
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 62.0 5.38e-01 100.0% 74.5%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 56.0 5.21e-01 91.8% 68.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.70 54.0 4.46e-01 86.9% 44.9%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 60.0 5.46e-01 100.0% 93.0%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 60.0 4.92e-01 100.0% 66.9%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.70 57.0 5.31e-01 95.1% 86.4%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.69 57.0 5.45e-01 93.4% 83.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.69 57.0 4.00e-01 95.1% 99.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.69 57.0 3.65e-01 93.4% 49.2%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.69 51.0 4.77e-01 88.5% 62.5%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.69 58.0 4.81e-01 100.0% 63.9%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.68 54.0 5.04e-01 90.2% 71.4%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 55.0 4.35e-01 93.4% 91.8%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 53.0 5.04e-01 91.8% 74.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 55.0 4.13e-01 96.7% 64.9%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 52.0 4.90e-01 93.4% 71.1%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 55.0 5.20e-01 95.1% 78.7%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.66 56.0 4.71e-01 100.0% 94.5%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 50.0 4.19e-01 85.2% 48.2%
4rg8A04 1.10.287.1240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 52.0 5.24e-01 91.8% 95.2%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 54.0 4.74e-01 100.0% 76.2%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.65 53.0 5.27e-01 95.1% 92.2%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.65 50.0 4.62e-01 86.9% 66.7%
2v6eA01 1.10.287.3180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 49.0 4.66e-01 85.2% 80.0%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 52.0 5.29e-01 93.4% 93.3%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 52.0 5.27e-01 93.4% 94.9%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.64 52.0 4.41e-01 96.7% 64.0%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 47.0 4.50e-01 86.9% 66.2%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 52.0 5.30e-01 98.4% 93.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.63 53.0 3.92e-01 100.0% 97.3%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 52.0 3.81e-01 100.0% 59.6%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 49.0 4.72e-01 91.8% 78.4%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.62 50.0 3.65e-01 93.4% 88.8%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.62 47.0 3.58e-01 93.4% 34.0%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.62 48.0 4.79e-01 91.8% 84.6%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 49.0 4.56e-01 93.4% 69.1%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.61 49.0 4.00e-01 91.8% 78.9%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.61 51.0 4.88e-01 100.0% 97.3%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 47.0 4.70e-01 91.8% 88.9%
3hhcC00 1.20.1250.60 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda 0.60 50.0 3.88e-01 98.4% 68.2%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 46.0 4.54e-01 88.5% 82.1%
2db7A01 6.10.250.980 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.60 44.0 4.64e-01 83.6% 94.3%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 42.0 3.97e-01 90.2% 62.7%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.58 48.0 4.71e-01 100.0% 87.3%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.58 42.0 4.45e-01 80.3% 100.0%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.58 47.0 4.59e-01 93.4% 92.5%
2vf8B02 1.20.1580.10 Mainly Alpha › Up-down Bundle › ABC transporter ATPase like fold › ABC transporter ATPase like domain 0.57 45.0 3.45e-01 91.8% 87.4%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 45.0 2.98e-01 90.2% 24.0%
1e6cA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 46.0 3.45e-01 100.0% 37.6%
1pixA03 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.51 37.0 2.55e-01 86.9% 26.4%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3728798 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.75 59.0 4.27e-01 86.9% 87.4%
3430567 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 60.0 6.04e-01 93.4% 91.7%
4959390 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.72 59.0 5.64e-01 93.4% 78.6%
3687276 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.72 60.0 5.42e-01 93.4% 69.4%
2832654 5058.1.1.1 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.72 53.0 4.70e-01 82.0% 71.3%
3991595 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.72 56.0 4.88e-01 86.9% 57.9%
3501709 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 55.0 5.23e-01 86.9% 74.7%
5047177 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 56.0 3.73e-01 86.9% 33.9%
2636640 192.15.1.3 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core 0.71 58.0 5.45e-01 93.4% 75.3%
3590184 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.70 59.0 4.63e-01 96.7% 57.8%
3930836 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 58.0 4.69e-01 95.1% 72.5%
4946455 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 56.0 5.17e-01 93.4% 75.0%
4801882 192.1.1.1 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › MCPsignal 0.67 54.0 5.33e-01 93.4% 87.5%
4234530 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 53.0 4.45e-01 93.4% 48.7%
4013672 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.66 53.0 4.67e-01 95.1% 59.0%
4089827 192.1.1.34 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF444 0.66 49.0 4.69e-01 83.6% 70.7%
3482907 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.66 54.0 4.49e-01 95.1% 52.2%
4211233 4120.1.1.60 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › GlutR_dimer 0.65 49.0 4.52e-01 82.0% 91.3%
3942662 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.65 55.0 4.86e-01 100.0% 90.5%
3248199 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.65 56.0 4.22e-01 98.4% 87.1%
3497897 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.65 54.0 5.24e-01 96.7% 87.1%
2067201 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.65 52.0 4.92e-01 93.4% 98.7%
3714244 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.65 51.0 5.16e-01 91.8% 91.7%
3855880 622.4.1.19 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › CD20 0.64 54.0 4.66e-01 100.0% 74.3%
4156067 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.63 53.0 4.44e-01 96.7% 69.1%
2055367 650.1.1.3 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › HsbA 0.63 50.0 4.86e-01 96.7% 80.0%
3239510 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.63 50.0 4.43e-01 93.4% 58.9%
4870082 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 45.0 4.42e-01 77.0% 89.4%
4378877 3711.1.1.20 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DUF444 0.63 48.0 4.55e-01 85.2% 72.0%
3477349 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 48.0 4.11e-01 86.9% 71.4%
5012687 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.62 49.0 4.34e-01 90.2% 71.6%
3966348 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.62 49.0 4.45e-01 88.5% 67.1%
4385365 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.61 49.0 4.21e-01 95.1% 54.5%
5034026 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.61 49.0 4.15e-01 90.2% 58.1%
3289802 284.1.1.0 a+b two layers › FKBP-like › FKBP-like › FKBP-like 0.61 48.0 2.86e-01 91.8% 21.8%
3359325 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.61 52.0 4.19e-01 100.0% 66.4%
3593724 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 48.0 3.90e-01 91.8% 63.2%
3491670 614.1.1.0 alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain 0.58 45.0 4.71e-01 91.8% 96.4%
4020464 1203.1.2.4 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Vps55 0.58 49.0 3.94e-01 98.4% 93.8%
2893266 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.58 46.0 4.16e-01 93.4% 62.0%
2914508 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.57 45.0 2.98e-01 93.4% 19.4%
5060383 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 45.0 4.30e-01 100.0% 76.0%
D2 medium residues 126-242
PDB
CATH (71)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.78 58.0 5.96e-01 76.1% 93.7%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.78 55.0 5.71e-01 72.6% 91.7%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.77 57.0 5.81e-01 75.2% 94.6%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 55.0 5.72e-01 74.4% 94.5%
1lj2A00 1.20.5.970 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Nonstructural RNA-binding protein 0.76 44.0 4.62e-01 78.6% 63.2%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.76 55.0 5.14e-01 77.8% 62.6%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.75 48.0 4.92e-01 86.3% 66.7%
2iiuA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 54.0 4.47e-01 79.5% 76.0%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 51.0 5.08e-01 84.6% 70.5%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.70 59.0 5.25e-01 92.3% 64.5%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 56.0 5.60e-01 93.2% 85.1%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 56.0 4.65e-01 92.3% 50.2%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 58.0 5.69e-01 93.2% 87.1%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 47.0 4.45e-01 70.9% 61.0%
6d5xA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.68 41.0 3.76e-01 75.2% 45.7%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 52.0 4.53e-01 82.1% 85.6%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.67 51.0 5.09e-01 81.2% 78.2%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.67 59.0 5.57e-01 95.7% 92.8%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 58.0 5.80e-01 95.7% 92.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.67 49.0 5.01e-01 82.9% 77.6%
1dlcA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.67 54.0 4.34e-01 86.3% 45.0%
2a2fX01 1.10.357.30 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain 0.66 48.0 4.30e-01 76.1% 76.6%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.66 46.0 4.94e-01 81.2% 83.3%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 43.0 4.02e-01 90.6% 54.5%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.65 57.0 4.75e-01 95.7% 58.0%
2j0wA02 1.20.120.1320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain 0.64 44.0 4.78e-01 95.7% 87.1%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.64 53.0 5.32e-01 94.9% 89.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 44.0 4.62e-01 70.9% 84.9%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 54.0 5.43e-01 100.0% 90.8%
2wl8C00 1.20.120.900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain 0.63 50.0 5.22e-01 90.6% 89.9%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 55.0 5.52e-01 96.6% 94.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 54.0 5.42e-01 95.7% 93.2%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 49.0 3.73e-01 83.8% 77.8%
2zxeA02 1.20.1110.10 Mainly Alpha › Up-down Bundle › Calcium-transporting ATPase, transmembrane domain › Calcium-transporting ATPase, transmembrane domain 0.62 44.0 3.07e-01 74.4% 31.0%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.62 52.0 5.14e-01 93.2% 85.4%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 43.0 4.11e-01 70.9% 70.6%
6nsjA00 1.25.40.600 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter 0.61 55.0 4.73e-01 98.3% 94.0%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 54.0 4.64e-01 99.1% 62.0%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.61 54.0 4.44e-01 97.4% 58.5%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.61 55.0 4.95e-01 99.1% 99.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.61 51.0 5.03e-01 92.3% 84.8%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.61 51.0 3.95e-01 88.9% 76.3%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 46.0 4.53e-01 90.6% 72.9%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.60 38.0 4.25e-01 90.6% 83.9%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.60 44.0 3.83e-01 76.9% 81.2%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.60 50.0 4.98e-01 92.3% 89.3%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 54.0 4.93e-01 99.1% 77.8%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 53.0 5.26e-01 98.3% 92.7%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 47.0 4.51e-01 90.6% 73.5%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.59 43.0 3.94e-01 89.7% 56.7%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 47.0 3.64e-01 84.6% 72.4%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.58 50.0 3.67e-01 95.7% 80.1%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.58 47.0 4.03e-01 86.3% 77.4%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 45.0 3.56e-01 84.6% 78.5%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.58 47.0 4.48e-01 91.5% 75.2%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.58 50.0 4.28e-01 92.3% 69.4%
3vadA01 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.57 42.0 3.87e-01 89.7% 58.3%
4cs9B02 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.56 37.0 3.91e-01 100.0% 73.8%
5gubB02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.56 49.0 3.77e-01 95.7% 66.0%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 48.0 4.03e-01 94.0% 80.6%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.55 46.0 4.21e-01 93.2% 95.1%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 44.0 4.47e-01 85.5% 92.2%
1qqtA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.55 47.0 4.44e-01 94.0% 80.4%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.54 45.0 3.87e-01 90.6% 85.9%
3dytA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 45.0 3.84e-01 92.3% 80.0%
3dxpA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.53 41.0 3.28e-01 82.9% 81.4%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 44.0 3.80e-01 92.3% 58.3%
4c3eM00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.52 38.0 3.47e-01 99.1% 57.4%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 35.0 3.44e-01 70.1% 63.8%
4g80T00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.51 43.0 4.08e-01 95.7% 77.7%
1zylA03 1.20.1270.170 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 39.0 4.18e-01 89.7% 95.1%
ECOD (86)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3833041 601.1.1.93 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1216 0.77 69.0 6.45e-01 95.7% 90.0%
3414672 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.76 53.0 4.38e-01 70.9% 80.0%
3401837 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.75 69.0 5.50e-01 100.0% 54.2%
3928340 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.74 53.0 4.48e-01 73.5% 93.0%
3740175 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.74 69.0 5.36e-01 100.0% 51.4%
3478015 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.73 70.0 5.43e-01 100.0% 53.3%
3637309 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.73 55.0 4.67e-01 78.6% 93.2%
3694381 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.72 67.0 5.31e-01 100.0% 52.8%
3626734 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.72 67.0 5.29e-01 100.0% 53.1%
3327396 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.72 69.0 5.40e-01 100.0% 54.0%
5023678 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.71 63.0 5.30e-01 94.9% 61.6%
3561117 601.1.3.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B 0.71 60.0 5.39e-01 93.2% 66.3%
3999246 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 53.0 5.53e-01 76.9% 94.3%
3169936 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.70 67.0 5.28e-01 100.0% 55.0%
3878135 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.70 59.0 5.33e-01 93.2% 66.3%
3540947 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.70 67.0 5.26e-01 100.0% 54.5%
4017167 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.69 63.0 4.73e-01 100.0% 86.4%
3276862 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.68 61.0 4.92e-01 95.7% 64.7%
3910532 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.68 58.0 5.72e-01 93.2% 88.8%
4593081 601.1.2.139 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30710 0.68 60.0 5.59e-01 96.6% 80.0%
4033191 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.68 58.0 4.76e-01 93.2% 59.5%
3466653 192.29.1.101 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N 0.68 47.0 4.78e-01 79.5% 73.0%
3610437 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.67 64.0 5.16e-01 100.0% 57.1%
3725075 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.67 61.0 4.66e-01 100.0% 84.8%
5076444 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.67 59.0 4.84e-01 95.7% 58.1%
3851394 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.67 54.0 5.29e-01 92.3% 79.2%
3970616 601.4.1.3 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 0.67 55.0 5.19e-01 93.2% 73.1%
3471902 601.1.1.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › VBS 0.67 59.0 5.24e-01 95.7% 74.5%
4999600 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.67 56.0 4.69e-01 92.3% 92.2%
3735641 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.66 61.0 4.57e-01 100.0% 83.9%
5010536 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.66 58.0 4.96e-01 94.9% 63.2%
3969049 601.4.1.3 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 0.66 55.0 4.93e-01 92.3% 64.2%
5083305 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.66 57.0 5.25e-01 96.6% 73.8%
4154382 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.66 58.0 5.06e-01 95.7% 69.9%
3502904 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.65 54.0 4.96e-01 86.3% 80.7%
3861221 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.65 54.0 4.72e-01 95.7% 59.2%
4028241 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.64 53.0 4.80e-01 87.2% 89.0%
3617986 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.64 58.0 4.99e-01 98.3% 90.0%
2105845 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.64 58.0 5.71e-01 100.0% 99.2%
3672657 3755.4.1.23 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7032 0.63 52.0 4.72e-01 89.7% 66.7%
2396196 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.63 55.0 5.32e-01 98.3% 84.1%
3457663 192.29.1.178 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28703 0.63 51.0 5.31e-01 98.3% 97.1%
3445405 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 51.0 5.08e-01 99.1% 85.0%
3562194 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 52.0 4.74e-01 95.7% 67.7%
3910430 611.8.1.1 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne 0.62 52.0 4.65e-01 90.6% 89.1%
3187372 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.62 55.0 4.73e-01 95.7% 63.9%
3236795 601.16.1.2 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT 0.62 56.0 5.26e-01 99.1% 80.7%
3249357 611.8.1.1 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne 0.62 54.0 4.92e-01 94.0% 79.4%
5047417 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 53.0 5.12e-01 100.0% 84.6%
3646192 611.7.1.11 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 0.62 50.0 4.85e-01 89.7% 76.9%
3464447 611.7.1.2 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc 0.62 52.0 4.81e-01 88.9% 78.6%
3397343 601.16.1.3 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C 0.61 51.0 4.94e-01 95.7% 81.5%
3596738 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.61 50.0 4.63e-01 86.3% 73.1%
3526861 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.61 42.0 4.34e-01 70.9% 77.3%
5049396 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.60 46.0 4.67e-01 93.2% 81.7%
3442785 611.7.1.11 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 0.60 51.0 4.78e-01 88.9% 76.4%
3236963 603.1.1.109 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF267 0.60 50.0 3.54e-01 90.6% 72.0%
3467026 611.7.1.13 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB10_N 0.60 50.0 4.31e-01 88.9% 58.9%
3885645 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 49.0 4.31e-01 95.7% 59.5%
3474226 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 50.0 4.77e-01 94.9% 81.4%
3339004 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.58 49.0 4.66e-01 89.7% 84.4%
3762384 601.16.1.9 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › PF31076 0.58 52.0 4.86e-01 99.1% 77.9%
3721596 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.58 47.0 4.55e-01 88.0% 76.2%
3784738 3755.4.1.43 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Ran-binding 0.58 48.0 4.46e-01 89.7% 86.0%
3246096 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.58 50.0 3.54e-01 96.6% 29.5%
4013154 601.16.1.18 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › VBS_C3G9 0.58 53.0 5.06e-01 100.0% 91.9%
3253932 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 49.0 4.84e-01 95.7% 91.2%
3249529 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.57 52.0 4.96e-01 98.3% 91.1%
3886005 601.2.1.0 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.57 50.0 5.10e-01 97.4% 100.0%
3913373 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 50.0 5.00e-01 98.3% 98.3%
4096580 1188.1.1.3 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp 0.56 50.0 4.27e-01 100.0% 62.4%
4019703 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.56 47.0 4.10e-01 89.7% 64.0%
3440521 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.56 46.0 4.33e-01 88.9% 75.0%
3926303 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.56 49.0 4.45e-01 98.3% 95.0%
3442186 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.56 45.0 4.41e-01 88.9% 80.8%
3426161 601.1.2.74 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N 0.55 46.0 4.51e-01 89.7% 87.7%
3310861 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.55 49.0 3.45e-01 100.0% 46.0%
3207391 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.55 49.0 4.56e-01 100.0% 79.3%
4410216 5068.1.1.1 alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C 0.55 43.0 4.40e-01 87.2% 84.1%
4953382 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.55 47.0 4.62e-01 95.7% 92.8%
4135359 4946.1.1.1 alpha bundles › helical domain in YacF-like proteins › helical domain in YacF-like proteins › helical domain in YacF-like proteins › ZapD 0.54 45.0 4.05e-01 92.3% 95.8%
4062828 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.54 47.0 3.88e-01 94.9% 55.6%
4593136 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.53 46.0 3.14e-01 95.7% 71.6%
5033654 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.53 45.0 3.81e-01 100.0% 53.8%
4023276 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.51 42.0 3.88e-01 89.7% 71.6%
3774261 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 42.0 3.00e-01 90.6% 55.6%