Back to structures

membrane_protein_US18

Euk-Vir

Human_herpesvirus_5

membrane_protein_US18__YP_002608320__Human_herpesvirus_5__10359

Identity

Accession:
YP_002608320 ↗
Protein ID:
membrane_protein_US18
Kingdom:
euk

Quality

77.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 50-272
PDB
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.71 50.0 4.85e-01 71.3% 98.4%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.69 25.0 4.31e-01 86.1% 97.4%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.67 32.0 4.62e-01 96.0% 97.1%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 27.0 4.12e-01 81.6% 90.8%
4jkvB02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 44.0 3.80e-01 70.0% 88.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 29.0 3.96e-01 91.9% 83.1%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.60 30.0 4.14e-01 75.3% 92.2%
3whjA00 6.10.140.1710 Special › Helix non-globular › Helix Hairpins › 0.60 28.0 3.77e-01 93.7% 84.7%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.59 28.0 3.29e-01 86.1% 62.7%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.59 40.0 4.61e-01 91.9% 94.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 31.0 4.22e-01 80.3% 100.0%
5tj5E00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.58 30.0 3.70e-01 99.6% 78.3%
4pdyA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.58 27.0 2.71e-01 89.2% 41.6%
3g5uA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 42.0 2.98e-01 74.0% 68.4%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.57 40.0 3.48e-01 70.0% 74.9%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.57 37.0 3.56e-01 81.2% 56.1%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.57 27.0 3.39e-01 84.3% 71.4%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.55 40.0 4.44e-01 94.6% 93.8%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 26.0 3.77e-01 75.3% 100.0%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.54 29.0 3.91e-01 72.6% 96.6%
2jokA01 1.10.4120.10 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain 0.53 29.0 3.25e-01 83.9% 65.7%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.53 34.0 4.06e-01 86.5% 95.9%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 32.0 4.03e-01 87.4% 100.0%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 40.0 4.10e-01 93.3% 80.9%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.52 37.0 4.16e-01 93.3% 93.1%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 41.0 4.16e-01 96.0% 82.4%
1qkrB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 36.0 4.02e-01 91.9% 87.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.51 26.0 3.10e-01 85.7% 70.2%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 26.0 3.19e-01 70.4% 75.5%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3478015 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.73 65.0 6.46e-01 93.3% 93.0%
5075726 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.72 64.0 6.45e-01 92.4% 94.2%
3486791 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.72 54.0 6.15e-01 76.7% 100.0%
3394147 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.72 63.0 6.33e-01 91.5% 93.3%
3478731 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.72 57.0 6.19e-01 81.2% 98.9%
3397602 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.72 63.0 6.28e-01 91.5% 93.3%
3390912 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.71 62.0 6.25e-01 91.0% 89.3%
3416752 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.71 65.0 6.57e-01 96.0% 95.6%
3939603 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.71 62.0 6.33e-01 91.5% 94.1%
3849233 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.71 60.0 6.20e-01 92.4% 92.5%
3411573 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.71 65.0 6.48e-01 96.4% 93.4%
3496559 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.70 62.0 6.27e-01 91.0% 93.6%
3399094 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.70 61.0 6.26e-01 91.0% 94.0%
3500534 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.70 59.0 6.09e-01 91.0% 92.4%
3989144 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.70 61.0 6.19e-01 91.5% 93.2%
3165172 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.69 57.0 6.02e-01 90.6% 94.0%
3471323 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.69 61.0 6.15e-01 91.5% 93.2%
3487803 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.69 61.0 6.05e-01 91.0% 90.8%
4024287 5001.1.1.81 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom 0.69 48.0 4.42e-01 70.9% 95.9%
4281235 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.69 59.0 6.02e-01 89.7% 95.5%
3409798 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 59.0 6.05e-01 89.2% 92.6%
3401837 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.68 61.0 6.17e-01 97.8% 93.8%
3936208 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 63.0 6.31e-01 96.0% 96.0%
3169936 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 61.0 6.17e-01 92.4% 94.5%
3540947 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 61.0 6.14e-01 92.8% 93.6%
3694381 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 58.0 5.96e-01 92.4% 92.5%
4370734 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 56.0 5.90e-01 91.0% 93.7%
3379165 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.68 59.0 5.58e-01 92.4% 77.2%
3227811 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 36.0 4.27e-01 99.6% 74.8%
3327396 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.65 57.0 5.82e-01 94.6% 93.5%
3386740 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.65 56.0 5.56e-01 91.5% 86.1%
3800644 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.65 56.0 5.76e-01 89.7% 94.8%
3964581 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.65 56.0 5.82e-01 91.5% 95.2%
3228630 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.64 46.0 3.98e-01 71.3% 95.8%
3219046 5001.1.1.16 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt 0.64 46.0 4.05e-01 71.3% 89.4%
4023355 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.64 48.0 4.46e-01 76.2% 98.5%
3735641 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.64 47.0 4.37e-01 75.3% 98.9%
3473124 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.64 50.0 5.00e-01 81.2% 80.4%
3923749 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 45.0 4.08e-01 71.3% 96.9%
3218437 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.63 45.0 4.01e-01 71.7% 93.2%
3833041 601.1.1.93 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1216 0.62 39.0 4.82e-01 92.4% 99.3%
3502146 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.61 43.0 3.96e-01 72.2% 94.1%
3178615 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.60 44.0 4.11e-01 73.5% 100.0%
3219525 5001.1.1.84 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz 0.59 43.0 3.90e-01 72.2% 92.0%
3655293 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.58 36.0 3.75e-01 87.4% 65.9%
5016105 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.58 37.0 3.97e-01 94.2% 74.1%
4988447 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 29.0 4.01e-01 93.7% 94.8%
4043617 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 50.0 4.63e-01 94.2% 89.1%
4509435 601.1.1.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS 0.56 37.0 4.35e-01 87.4% 93.1%
5006471 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.55 40.0 4.46e-01 91.9% 95.9%
3243897 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.54 32.0 3.96e-01 82.1% 93.6%
3241030 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.53 37.0 3.33e-01 71.7% 79.0%
3947112 192.8.1.394 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › MscS_porin 0.52 38.0 3.91e-01 74.4% 79.1%
3613274 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.51 41.0 4.13e-01 81.2% 99.5%