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membrane_protein_US18
Euk-VirCynomolgus_macaque_cytomegalovirus_strain_Ottawa
membrane_protein_US18__YP_004933976__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969
Identity
- Accession:
- YP_004933976 ↗
- Protein ID:
- membrane_protein_US18
- Kingdom:
- euk
Quality
83.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cynomolgus_macaque_cytomegalovirus_strain_Ottawa
TaxID: 944969
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 66-116
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.80 | 71.0 | 5.69e-01 | 100.0% | 66.7% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 69.0 | 6.04e-01 | 100.0% | 65.4% |
| 2fjcB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.79 | 70.0 | 4.91e-01 | 100.0% | 35.3% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 69.0 | 6.11e-01 | 98.0% | 91.8% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 66.0 | 6.09e-01 | 96.1% | 100.0% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.78 | 63.0 | 6.48e-01 | 98.0% | 97.9% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.78 | 69.0 | 5.14e-01 | 100.0% | 48.8% |
| 3uj9A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.77 | 64.0 | 4.09e-01 | 96.1% | 19.4% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.77 | 66.0 | 5.09e-01 | 100.0% | 44.5% |
| 2mpnA00 | 6.10.140.1340 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 67.0 | 6.13e-01 | 100.0% | 83.8% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.76 | 63.0 | 5.01e-01 | 92.2% | 68.6% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 64.0 | 4.51e-01 | 100.0% | 68.6% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 64.0 | 5.43e-01 | 96.1% | 76.5% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 63.0 | 6.23e-01 | 100.0% | 88.9% |
| 1yzmA00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.75 | 59.0 | 6.13e-01 | 96.1% | 100.0% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 65.0 | 4.70e-01 | 100.0% | 44.9% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.75 | 64.0 | 4.25e-01 | 100.0% | 24.1% |
| 1x0tA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 54.0 | 5.11e-01 | 100.0% | 65.6% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 60.0 | 4.34e-01 | 92.2% | 39.2% |
| 3kwoA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 62.0 | 4.56e-01 | 100.0% | 79.2% |
| 2etnB01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.73 | 62.0 | 5.57e-01 | 100.0% | 76.3% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.73 | 62.0 | 5.52e-01 | 96.1% | 71.6% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.73 | 62.0 | 5.29e-01 | 100.0% | 58.5% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 64.0 | 6.01e-01 | 100.0% | 98.4% |
| 6n7pX01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.73 | 62.0 | 3.86e-01 | 100.0% | 32.4% |
| 1iq0A03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.72 | 63.0 | 4.85e-01 | 100.0% | 47.4% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 59.0 | 5.50e-01 | 100.0% | 75.4% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.71 | 62.0 | 5.51e-01 | 100.0% | 68.4% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 59.0 | 5.10e-01 | 100.0% | 59.0% |
| 3ilxA02 | 1.10.287.2170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 50.0 | 5.27e-01 | 86.3% | 90.9% |
| 4hb1A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.70 | 53.0 | 5.55e-01 | 84.3% | 100.0% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.70 | 58.0 | 5.34e-01 | 100.0% | 73.2% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 60.0 | 4.56e-01 | 100.0% | 41.1% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 55.0 | 5.29e-01 | 98.0% | 93.8% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.68 | 53.0 | 5.31e-01 | 92.2% | 86.5% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 55.0 | 4.03e-01 | 98.0% | 35.8% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.67 | 51.0 | 5.08e-01 | 96.1% | 82.1% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.66 | 56.0 | 4.52e-01 | 96.1% | 88.0% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.66 | 54.0 | 4.98e-01 | 98.0% | 97.1% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 55.0 | 5.52e-01 | 98.0% | 98.0% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 47.0 | 4.69e-01 | 82.4% | 79.6% |
| 1luwA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.63 | 51.0 | 4.92e-01 | 100.0% | 79.7% |
| 1bf3A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.62 | 50.0 | 3.33e-01 | 96.1% | 77.5% |
| 3aogA01 | 1.10.8.1210 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.57 | 42.0 | 3.95e-01 | 82.4% | 64.5% |
| 4dgwB01 | 1.10.10.790 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module | 0.57 | 41.0 | 4.18e-01 | 86.3% | 78.0% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4965021 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.82 | 69.0 | 6.77e-01 | 100.0% | 85.5% |
| 3336677 | 605.1.1.132 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 | 0.80 | 68.0 | 5.96e-01 | 100.0% | 64.0% |
| 4025 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.80 | 71.0 | 5.69e-01 | 100.0% | 66.7% |
| 2841849 | 3710.1.1.0 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain | 0.80 | 65.0 | 6.21e-01 | 100.0% | 78.7% |
| 3186698 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.79 | 69.0 | 5.97e-01 | 100.0% | 86.3% |
| 3845790 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.78 | 65.0 | 5.23e-01 | 100.0% | 48.0% |
| 4930198 | 605.1.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim | 0.78 | 65.0 | 6.20e-01 | 100.0% | 80.0% |
| 3712097 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.77 | 68.0 | 5.65e-01 | 100.0% | 57.8% |
| 4957093 | 3456.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › Oxidored_q4 | 0.77 | 63.0 | 4.87e-01 | 100.0% | 40.3% |
| 4572664 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.77 | 65.0 | 5.95e-01 | 100.0% | 72.9% |
| None | — | 0.76 | 62.0 | 3.56e-01 | 100.0% | 9.3% | |
| 3262528 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.75 | 60.0 | 5.23e-01 | 100.0% | 57.5% |
| 3597506 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.74 | 62.0 | 5.49e-01 | 96.1% | 70.7% |
| 3491418 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.73 | 63.0 | 5.60e-01 | 100.0% | 72.0% |
| 4961508 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 62.0 | 5.57e-01 | 100.0% | 72.0% |
| 2674763 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.72 | 62.0 | 5.50e-01 | 98.0% | 70.7% |
| 3944931 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 59.0 | 5.06e-01 | 100.0% | 73.3% |
| 3410865 | 64.4.1.0 ↗ | beta meanders › WW domain-like › Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain › Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain | 0.68 | 59.0 | 5.78e-01 | 100.0% | 92.7% |
| 3230775 | 192.1.1.25 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › VPS18_RING_C | 0.66 | 55.0 | 4.44e-01 | 100.0% | 47.3% |
| 3933364 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.65 | 48.0 | 4.53e-01 | 88.2% | 64.6% |
| 3788397 | 4030.1.1.0 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz | 0.64 | 48.0 | 4.32e-01 | 84.3% | 70.7% |
| 4629340 | 3928.1.1.1 ↗ | alpha bundles › Cell division protein CrgA › Cell division protein CrgA › Cell division protein CrgA › CrgA | 0.61 | 50.0 | 4.95e-01 | 100.0% | 94.4% |
| 3505989 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.54 | 46.0 | 3.74e-01 | 100.0% | 54.3% |
D2
medium
residues 117-169
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z72A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.74 | 64.0 | 4.22e-01 | 98.1% | 24.1% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 50.0 | 4.07e-01 | 73.6% | 38.8% |
| 1e6dM01 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.58 | 50.0 | 3.69e-01 | 98.1% | 90.9% |
| 4na1B02 | 1.10.1240.100 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.51 | 36.0 | 3.12e-01 | 79.2% | 45.3% |
D3
medium
residues 170-266
Domain cluster:
rep: Cy199__YP_009337599__Cynomolgus_cytomegalovirus__1919083__D170-243