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membrane_protein_US18
Euk-VirCercopithecine_betaherpesvirus_5
membrane_protein_US18__YP_004936128__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936128 ↗
- Protein ID:
- membrane_protein_US18
- Kingdom:
- euk
Quality
83.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 111-247
Domain cluster:
rep: membrane_protein_US17__YP_004936127__Cercopithecine_betaherpesvirus_5__50292__D117-239
CATH (65)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.71 | 53.0 | 5.41e-01 | 89.1% | 78.2% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 63.0 | 5.03e-01 | 100.0% | 86.0% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 41.0 | 5.07e-01 | 95.6% | 92.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.68 | 44.0 | 4.72e-01 | 76.6% | 75.9% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.67 | 54.0 | 4.37e-01 | 89.8% | 45.9% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 5.66e-01 | 92.0% | 94.4% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 56.0 | 4.82e-01 | 89.1% | 94.2% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.66 | 46.0 | 4.74e-01 | 71.5% | 91.0% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 59.0 | 4.58e-01 | 99.3% | 89.8% |
| 1oedA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.65 | 53.0 | 5.46e-01 | 92.0% | 92.1% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.65 | 55.0 | 4.78e-01 | 91.2% | 92.0% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 48.0 | 3.94e-01 | 78.8% | 71.1% |
| 4bg5B00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.64 | 51.0 | 4.41e-01 | 82.5% | 73.4% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.63 | 50.0 | 4.86e-01 | 88.3% | 75.5% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.62 | 44.0 | 4.69e-01 | 89.8% | 83.1% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 53.0 | 4.86e-01 | 91.2% | 77.8% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.62 | 51.0 | 4.84e-01 | 86.1% | 81.4% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 48.0 | 3.87e-01 | 82.5% | 80.4% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 48.0 | 4.16e-01 | 81.0% | 85.2% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 40.0 | 4.12e-01 | 81.8% | 67.7% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.62 | 51.0 | 5.14e-01 | 89.1% | 97.1% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 48.0 | 5.16e-01 | 89.8% | 95.0% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 49.0 | 5.24e-01 | 89.8% | 97.5% |
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 55.0 | 4.13e-01 | 100.0% | 91.9% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 37.0 | 4.27e-01 | 97.8% | 82.2% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.61 | 37.0 | 4.23e-01 | 86.9% | 81.2% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 47.0 | 4.13e-01 | 81.0% | 85.5% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 45.0 | 5.03e-01 | 86.9% | 100.0% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 44.0 | 5.00e-01 | 84.7% | 100.0% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 48.0 | 4.31e-01 | 84.7% | 88.8% |
| 2yinA03 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.60 | 36.0 | 3.78e-01 | 97.1% | 64.1% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.60 | 48.0 | 3.93e-01 | 84.7% | 79.6% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.60 | 51.0 | 3.92e-01 | 92.0% | 86.4% |
| 3ns4A00 | 1.10.357.110 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Vacuolar protein sorting-associated protein 53, C-terminus | 0.60 | 46.0 | 4.07e-01 | 81.8% | 80.0% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.59 | 48.0 | 4.91e-01 | 92.0% | 87.8% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 52.0 | 4.14e-01 | 96.4% | 91.7% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 53.0 | 4.50e-01 | 95.6% | 67.4% |
| 3bvxA02 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.58 | 37.0 | 4.07e-01 | 87.6% | 78.4% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 47.0 | 4.67e-01 | 89.1% | 82.5% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 47.0 | 4.82e-01 | 86.9% | 90.0% |
| 1dofA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.58 | 45.0 | 3.74e-01 | 82.5% | 64.3% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 47.0 | 4.52e-01 | 87.6% | 90.6% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.57 | 43.0 | 4.08e-01 | 78.1% | 68.5% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.57 | 46.0 | 4.48e-01 | 83.9% | 83.0% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 49.0 | 5.09e-01 | 94.2% | 98.5% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.57 | 46.0 | 3.65e-01 | 83.2% | 77.4% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.57 | 47.0 | 3.77e-01 | 89.1% | 80.2% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 43.0 | 3.49e-01 | 79.6% | 84.9% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.56 | 41.0 | 3.38e-01 | 75.9% | 78.9% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.56 | 39.0 | 3.64e-01 | 71.5% | 100.0% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.55 | 42.0 | 3.34e-01 | 77.4% | 40.5% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.55 | 35.0 | 3.79e-01 | 94.9% | 75.2% |
| 3i1aA03 | 1.20.58.840 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 41.0 | 4.40e-01 | 76.6% | 92.2% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 45.0 | 4.37e-01 | 94.9% | 80.5% |
| 3qa8A04 | 1.20.1270.250 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 43.0 | 3.63e-01 | 84.7% | 75.5% |
| 1auwA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.54 | 46.0 | 3.90e-01 | 91.2% | 78.5% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 40.0 | 3.86e-01 | 77.4% | 98.7% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 47.0 | 4.02e-01 | 94.9% | 100.0% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.53 | 42.0 | 4.32e-01 | 83.9% | 87.6% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 39.0 | 3.79e-01 | 78.1% | 83.3% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.51 | 45.0 | 3.71e-01 | 94.2% | 64.8% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 41.0 | 3.77e-01 | 86.1% | 66.7% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.51 | 45.0 | 3.89e-01 | 98.5% | 78.5% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.50 | 41.0 | 4.17e-01 | 89.8% | 88.6% |
| 3u66A00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.50 | 39.0 | 3.70e-01 | 86.1% | 67.9% |
ECOD (74)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3216129 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.78 | 61.0 | 6.39e-01 | 83.2% | 88.8% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 49.0 | 5.10e-01 | 81.8% | 72.8% |
| 3855328 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.72 | 49.0 | 5.81e-01 | 92.0% | 98.9% |
| 5066136 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.70 | 57.0 | 4.81e-01 | 86.9% | 92.8% |
| 3420329 | 109.4.1.1184 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF747 | 0.70 | 48.0 | 3.78e-01 | 70.8% | 74.0% |
| 4479929 | 601.1.1.89 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC | 0.69 | 59.0 | 5.18e-01 | 90.5% | 94.9% |
| 3939603 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.68 | 62.0 | 5.16e-01 | 96.4% | 59.1% |
| 3936208 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.67 | 63.0 | 5.20e-01 | 97.8% | 60.4% |
| 3211056 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 47.0 | 4.39e-01 | 75.2% | 58.2% |
| 3283967 | 601.1.1.83 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF4386 | 0.67 | 53.0 | 4.51e-01 | 83.2% | 71.6% |
| 3511623 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.66 | 58.0 | 5.26e-01 | 95.6% | 70.6% |
| 3479389 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.66 | 57.0 | 5.14e-01 | 92.0% | 70.8% |
| 4941651 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.66 | 54.0 | 4.70e-01 | 86.1% | 89.5% |
| 3480861 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.65 | 50.0 | 4.05e-01 | 79.6% | 85.9% |
| 3701003 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.65 | 43.0 | 4.22e-01 | 84.7% | 62.1% |
| 3321745 | 601.1.1.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RPW8 | 0.65 | 50.0 | 5.21e-01 | 86.9% | 87.2% |
| 3241444 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.65 | 45.0 | 3.88e-01 | 71.5% | 74.5% |
| 3253938 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 50.0 | 5.44e-01 | 89.1% | 96.5% |
| 3839810 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.64 | 48.0 | 4.80e-01 | 85.4% | 75.0% |
| 3582803 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.64 | 49.0 | 5.34e-01 | 86.9% | 95.7% |
| 4011437 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 58.0 | 4.79e-01 | 100.0% | 89.4% |
| 4874833 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.63 | 52.0 | 4.97e-01 | 88.3% | 89.9% |
| 4991155 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.63 | 44.0 | 3.86e-01 | 92.0% | 47.8% |
| 4258378 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.63 | 54.0 | 4.33e-01 | 93.4% | 100.0% |
| 3972755 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.63 | 44.0 | 4.65e-01 | 73.7% | 82.2% |
| 3489411 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.62 | 51.0 | 4.85e-01 | 87.6% | 78.2% |
| 3253931 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 54.0 | 5.18e-01 | 92.7% | 88.4% |
| 3495478 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 52.0 | 5.32e-01 | 89.1% | 99.2% |
| 4015359 | 3567.1.1.51 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin | 0.62 | 52.0 | 4.46e-01 | 90.5% | 86.4% |
| 3615123 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 50.0 | 4.48e-01 | 83.9% | 80.0% |
| 3990526 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.61 | 47.0 | 3.98e-01 | 81.0% | 70.4% |
| 3443525 | 611.7.1.1 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MLKL_N | 0.61 | 51.0 | 5.22e-01 | 86.1% | 90.8% |
| 4150398 | 633.23.1.32 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom | 0.61 | 44.0 | 4.22e-01 | 83.2% | 63.1% |
| 4475459 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.61 | 52.0 | 5.22e-01 | 92.7% | 89.3% |
| 4319295 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.61 | 45.0 | 5.12e-01 | 90.5% | 100.0% |
| 3872220 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 39.0 | 4.27e-01 | 97.8% | 79.1% |
| 5076088 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.60 | 53.0 | 5.35e-01 | 92.7% | 96.3% |
| 3171851 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 53.0 | 4.99e-01 | 92.0% | 81.9% |
| 3283510 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.60 | 51.0 | 4.88e-01 | 89.1% | 87.7% |
| 4023330 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.60 | 50.0 | 4.63e-01 | 89.1% | 72.6% |
| 3967683 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 48.0 | 4.69e-01 | 87.6% | 78.0% |
| 3908488 | 633.23.1.35 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Clarin-2 | 0.60 | 46.0 | 3.94e-01 | 80.3% | 68.2% |
| 3669753 | 3684.1.1.34 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › Rx_N | 0.59 | 44.0 | 4.62e-01 | 86.1% | 84.0% |
| 3957075 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.59 | 49.0 | 4.81e-01 | 89.8% | 86.0% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 51.0 | 5.07e-01 | 92.7% | 90.0% |
| 4997943 | 5039.1.1.2 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › DUF420 | 0.59 | 50.0 | 4.96e-01 | 90.5% | 89.6% |
| 3502455 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.59 | 43.0 | 3.69e-01 | 75.2% | 79.8% |
| 3495033 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.59 | 46.0 | 3.99e-01 | 82.5% | 79.4% |
| 3686419 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.59 | 46.0 | 4.51e-01 | 82.5% | 81.3% |
| 4354686 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.59 | 45.0 | 4.80e-01 | 83.2% | 91.7% |
| 3586824 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.58 | 45.0 | 3.23e-01 | 89.1% | 26.7% |
| 3749164 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.58 | 40.0 | 3.61e-01 | 70.8% | 82.0% |
| 4955364 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.58 | 53.0 | 4.55e-01 | 100.0% | 95.3% |
| 3639116 | 3285.1.1.1 ↗ | alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain › ALIX_LYPXL_bnd | 0.58 | 48.0 | 3.51e-01 | 86.1% | 68.8% |
| 3673192 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 50.0 | 4.67e-01 | 93.4% | 74.7% |
| 3468530 | 611.2.1.2 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N | 0.58 | 37.0 | 3.94e-01 | 84.7% | 73.9% |
| 3807188 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.58 | 46.0 | 4.46e-01 | 83.9% | 76.0% |
| 3972445 | 611.4.1.2 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like › Acyl-CoA_dh_C | 0.57 | 46.0 | 4.64e-01 | 84.7% | 91.1% |
| 3670937 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.57 | 45.0 | 4.62e-01 | 83.9% | 86.9% |
| 3479138 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.57 | 46.0 | 3.97e-01 | 85.4% | 79.1% |
| 3805163 | 174.1.1.63 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PGG | 0.57 | 43.0 | 4.33e-01 | 85.4% | 77.1% |
| 5021548 | 3562.1.1.0 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 | 0.57 | 46.0 | 4.64e-01 | 85.4% | 87.1% |
| 3436207 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.56 | 45.0 | 4.55e-01 | 84.7% | 85.0% |
| 3503775 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.56 | 46.0 | 3.85e-01 | 85.4% | 76.0% |
| 3471633 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.56 | 46.0 | 3.83e-01 | 86.1% | 75.2% |
| 5051294 | 601.41.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein | 0.56 | 41.0 | 4.32e-01 | 85.4% | 85.6% |
| 3393914 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.55 | 48.0 | 3.81e-01 | 94.2% | 48.9% |
| 5037027 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.55 | 40.0 | 3.95e-01 | 87.6% | 69.3% |
| 5071781 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.55 | 44.0 | 4.07e-01 | 97.1% | 66.9% |
| 3442603 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.54 | 44.0 | 4.56e-01 | 85.4% | 90.0% |
| 3678942 | 611.7.1.14 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7792 | 0.53 | 40.0 | 4.18e-01 | 81.8% | 83.1% |
| 3644738 | 192.29.1.48 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Chloroplast_duf | 0.52 | 42.0 | 3.62e-01 | 86.1% | 82.6% |
| 4486891 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.51 | 44.0 | 3.36e-01 | 94.2% | 80.6% |
| 3188754 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 41.0 | 3.12e-01 | 92.7% | 88.6% |