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membrane_protein_US20
Euk-VirCercopithecine_betaherpesvirus_5
membrane_protein_US20__YP_004936130__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936130 ↗
- Protein ID:
- membrane_protein_US20
- Kingdom:
- euk
Quality
87.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 61-117
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.72 | 58.0 | 4.75e-01 | 91.2% | 65.5% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 57.0 | 4.78e-01 | 93.0% | 52.9% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.70 | 58.0 | 4.28e-01 | 96.5% | 49.7% |
| 7e84A02 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.70 | 58.0 | 4.46e-01 | 96.5% | 50.4% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 57.0 | 5.50e-01 | 96.5% | 94.0% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 55.0 | 5.33e-01 | 96.5% | 89.1% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 53.0 | 4.98e-01 | 96.5% | 76.6% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.66 | 52.0 | 5.13e-01 | 93.0% | 87.5% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.66 | 51.0 | 4.67e-01 | 98.2% | 63.7% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 48.0 | 4.48e-01 | 86.0% | 61.3% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.66 | 54.0 | 4.76e-01 | 96.5% | 63.3% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 53.0 | 4.85e-01 | 94.7% | 74.1% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 53.0 | 5.33e-01 | 96.5% | 93.3% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 55.0 | 5.35e-01 | 98.2% | 98.5% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 54.0 | 5.14e-01 | 100.0% | 87.3% |
| 1grjA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.65 | 55.0 | 5.15e-01 | 100.0% | 97.3% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 51.0 | 5.27e-01 | 89.5% | 100.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 53.0 | 3.75e-01 | 96.5% | 29.4% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 49.0 | 4.60e-01 | 93.0% | 67.6% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 52.0 | 4.92e-01 | 100.0% | 85.1% |
| 1sg7A00 | 1.10.1740.70 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB | 0.62 | 37.0 | 3.39e-01 | 73.7% | 44.0% |
| 1b06A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.61 | 50.0 | 4.81e-01 | 96.5% | 94.0% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 48.0 | 4.06e-01 | 94.7% | 74.8% |
| 3kr9A02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 45.0 | 4.50e-01 | 94.7% | 80.3% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 50.0 | 4.43e-01 | 100.0% | 82.2% |
| 3smtA02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.60 | 53.0 | 3.82e-01 | 100.0% | 64.0% |
| 1e6cA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 46.0 | 3.37e-01 | 93.0% | 80.6% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.54 | 43.0 | 4.08e-01 | 100.0% | 77.0% |
| 5h28A02 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.52 | 39.0 | 3.23e-01 | 86.0% | 43.8% |
| 1vk0A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.51 | 44.0 | 3.08e-01 | 100.0% | 76.0% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3968144 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 60.0 | 5.83e-01 | 91.2% | 83.1% |
| 3609066 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 62.0 | 5.04e-01 | 100.0% | 65.2% |
| 4959390 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 60.0 | 5.70e-01 | 96.5% | 88.6% |
| 3428041 | 3465.1.1.0 ↗ | extended segments › Subunit PsaX of photosystem I reaction centre › Subunit PsaX of photosystem I reaction centre › Subunit PsaX of photosystem I reaction centre | 0.71 | 52.0 | 4.90e-01 | 89.5% | 64.3% |
| 3501709 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.70 | 57.0 | 5.25e-01 | 91.2% | 74.7% |
| 5060491 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.70 | 58.0 | 4.67e-01 | 96.5% | 51.7% |
| 4081303 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.69 | 52.0 | 5.42e-01 | 100.0% | 94.0% |
| 3563272 | 375.1.1.202 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Tmemb_55A | 0.69 | 54.0 | 5.54e-01 | 89.5% | 96.4% |
| 3650275 | 3602.1.1.0 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain | 0.69 | 54.0 | 5.03e-01 | 89.5% | 70.7% |
| 4876530 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.68 | 56.0 | 5.02e-01 | 96.5% | 69.0% |
| 4013672 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.68 | 56.0 | 4.74e-01 | 96.5% | 55.0% |
| 3176852 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.67 | 56.0 | 4.47e-01 | 98.2% | 47.2% |
| 3909017 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.67 | 56.0 | 4.90e-01 | 96.5% | 68.9% |
| 3728798 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 55.0 | 3.99e-01 | 96.5% | 32.0% |
| 3703277 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.67 | 55.0 | 5.19e-01 | 100.0% | 77.1% |
| 4638458 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.67 | 52.0 | 5.02e-01 | 87.7% | 83.1% |
| 3386554 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.67 | 53.0 | 4.92e-01 | 91.2% | 70.7% |
| 4945538 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.66 | 52.0 | 4.95e-01 | 91.2% | 80.0% |
| 5045310 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.66 | 56.0 | 5.28e-01 | 98.2% | 97.1% |
| 4012593 | 150.5.1.85 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › UPF0220 | 0.66 | 54.0 | 4.50e-01 | 93.0% | 53.3% |
| 3906129 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 55.0 | 4.44e-01 | 100.0% | 76.0% |
| 3316526 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.65 | 54.0 | 4.62e-01 | 96.5% | 60.0% |
| 3872905 | 301.6.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like › Tubulin_C | 0.65 | 52.0 | 3.81e-01 | 96.5% | 63.8% |
| 5055683 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.65 | 55.0 | 4.02e-01 | 100.0% | 33.5% |
| 4089827 | 192.1.1.34 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF444 | 0.64 | 51.0 | 4.76e-01 | 91.2% | 69.3% |
| 4638470 | 101.1.2.311 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA12 | 0.64 | 52.0 | 3.83e-01 | 96.5% | 38.2% |
| 3218641 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 51.0 | 4.16e-01 | 94.7% | 45.0% |
| 3471215 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.64 | 52.0 | 4.89e-01 | 98.2% | 82.7% |
| 3578352 | 109.4.1.884 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_UBP24_USP9X-Y | 0.63 | 53.0 | 3.80e-01 | 100.0% | 36.3% |
| 3611462 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 51.0 | 4.00e-01 | 96.5% | 41.4% |
| 3531423 | 5106.1.1.14 ↗ | extended segments › PetG subunit of the cytochrome b6f complex › PetG subunit of the cytochrome b6f complex › PetG subunit of the cytochrome b6f complex › TMEM174 | 0.63 | 51.0 | 5.23e-01 | 94.7% | 100.0% |
| 4870082 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.63 | 48.0 | 4.69e-01 | 89.5% | 86.4% |
| 3855880 | 622.4.1.19 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › CD20 | 0.63 | 52.0 | 4.42e-01 | 100.0% | 69.5% |
| 4378877 | 3711.1.1.20 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DUF444 | 0.63 | 51.0 | 4.78e-01 | 98.2% | 73.3% |
| 3940790 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 47.0 | 4.09e-01 | 96.5% | 57.0% |
| 3494616 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.58 | 47.0 | 4.27e-01 | 98.2% | 91.8% |
| 3839303 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.56 | 47.0 | 4.51e-01 | 100.0% | 90.0% |
D2
medium
residues 118-242
Domain cluster:
rep: membrane_protein_US17__YP_004936127__Cercopithecine_betaherpesvirus_5__50292__D117-239
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01027.27 best | Bax1-I | 41.0 | 2.70e-10 | 96.8% | 55.1% |
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 65.0 | 5.37e-01 | 98.4% | 87.6% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.71 | 51.0 | 5.57e-01 | 87.2% | 88.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.68 | 46.0 | 4.82e-01 | 79.2% | 75.0% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 58.0 | 4.43e-01 | 90.4% | 92.2% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.68 | 55.0 | 5.41e-01 | 93.6% | 79.7% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 58.0 | 5.82e-01 | 94.4% | 89.1% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 57.0 | 4.77e-01 | 90.4% | 95.7% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 55.0 | 4.80e-01 | 87.2% | 89.9% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 4.55e-01 | 90.4% | 52.2% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.67 | 57.0 | 5.31e-01 | 92.0% | 74.8% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 53.0 | 4.07e-01 | 84.8% | 80.4% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 51.0 | 4.09e-01 | 83.2% | 79.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 46.0 | 4.65e-01 | 82.4% | 73.0% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.65 | 56.0 | 5.06e-01 | 95.2% | 69.0% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 44.0 | 4.35e-01 | 86.4% | 64.7% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 55.0 | 5.66e-01 | 92.0% | 95.8% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.64 | 43.0 | 4.65e-01 | 77.6% | 82.4% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 52.0 | 4.06e-01 | 85.6% | 82.3% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 52.0 | 4.49e-01 | 85.6% | 66.1% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 54.0 | 5.16e-01 | 93.6% | 79.0% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.64 | 54.0 | 4.78e-01 | 90.4% | 71.3% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.64 | 57.0 | 5.26e-01 | 97.6% | 100.0% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.64 | 48.0 | 3.99e-01 | 78.4% | 89.2% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.63 | 55.0 | 5.05e-01 | 96.0% | 72.8% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.63 | 48.0 | 4.93e-01 | 93.6% | 83.1% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 55.0 | 4.86e-01 | 94.4% | 77.8% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 58.0 | 5.72e-01 | 98.4% | 95.4% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.63 | 48.0 | 4.35e-01 | 79.2% | 70.9% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.63 | 54.0 | 4.82e-01 | 92.8% | 66.1% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 54.0 | 5.58e-01 | 99.2% | 98.3% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.62 | 52.0 | 5.33e-01 | 93.6% | 94.2% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.61 | 54.0 | 3.95e-01 | 95.2% | 79.2% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.61 | 43.0 | 4.55e-01 | 83.2% | 81.2% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 50.0 | 3.90e-01 | 87.2% | 82.0% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.61 | 54.0 | 4.51e-01 | 96.8% | 88.0% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.61 | 52.0 | 4.91e-01 | 92.8% | 80.4% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 50.0 | 4.69e-01 | 86.4% | 75.7% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 52.0 | 5.40e-01 | 94.4% | 99.1% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.60 | 53.0 | 4.59e-01 | 97.6% | 69.4% |
| 3gi8C00 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.60 | 51.0 | 3.54e-01 | 93.6% | 67.6% |
| 4xxiA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.60 | 39.0 | 3.70e-01 | 79.2% | 55.1% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 48.0 | 3.95e-01 | 87.2% | 78.9% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.59 | 50.0 | 3.71e-01 | 89.6% | 41.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 52.0 | 5.20e-01 | 96.8% | 97.7% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.59 | 48.0 | 4.98e-01 | 93.6% | 94.8% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.59 | 51.0 | 3.91e-01 | 93.6% | 80.2% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 49.0 | 4.10e-01 | 89.6% | 82.4% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.58 | 49.0 | 4.55e-01 | 92.0% | 72.8% |
| 3vkgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.58 | 46.0 | 4.37e-01 | 83.2% | 79.6% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.58 | 49.0 | 4.75e-01 | 88.8% | 85.3% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.57 | 50.0 | 4.45e-01 | 97.6% | 100.0% |
| 4bg5B00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.57 | 48.0 | 4.11e-01 | 90.4% | 85.4% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.56 | 45.0 | 4.68e-01 | 90.4% | 92.0% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 35.0 | 3.72e-01 | 89.6% | 69.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 34.0 | 2.73e-01 | 100.0% | 31.6% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.56 | 49.0 | 4.04e-01 | 95.2% | 89.3% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 49.0 | 4.62e-01 | 98.4% | 79.7% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.55 | 44.0 | 3.81e-01 | 84.8% | 71.0% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 46.0 | 3.63e-01 | 89.6% | 82.9% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 49.0 | 3.89e-01 | 96.8% | 71.9% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 45.0 | 3.85e-01 | 88.8% | 85.3% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.54 | 48.0 | 4.02e-01 | 99.2% | 85.3% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 4.27e-01 | 97.6% | 78.6% |
| 1zylA03 | 1.20.1270.170 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 35.0 | 3.88e-01 | 88.8% | 82.5% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.53 | 39.0 | 4.15e-01 | 89.6% | 92.4% |
| 1uddA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.53 | 46.0 | 3.90e-01 | 96.8% | 90.2% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.52 | 40.0 | 3.86e-01 | 80.8% | 86.9% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.51 | 40.0 | 4.18e-01 | 83.2% | 93.8% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 42.0 | 3.77e-01 | 88.8% | 67.3% |
| 3dxpA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.50 | 40.0 | 3.25e-01 | 84.8% | 75.4% |
ECOD (91)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3852543 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.73 | 54.0 | 5.74e-01 | 90.4% | 87.3% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.72 | 52.0 | 5.25e-01 | 84.8% | 73.6% |
| 5075726 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.71 | 67.0 | 5.33e-01 | 98.4% | 54.2% |
| 3694381 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.71 | 66.0 | 5.33e-01 | 98.4% | 56.1% |
| 3577761 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.70 | 64.0 | 6.16e-01 | 98.4% | 85.0% |
| 3448448 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.70 | 64.0 | 5.18e-01 | 94.4% | 55.4% |
| 3486791 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.70 | 63.0 | 5.56e-01 | 93.6% | 69.4% |
| 5083715 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.70 | 63.0 | 5.07e-01 | 98.4% | 54.4% |
| 3500534 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.69 | 62.0 | 5.05e-01 | 95.2% | 55.2% |
| 3740175 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.69 | 65.0 | 5.21e-01 | 99.2% | 55.5% |
| 3386740 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.69 | 62.0 | 4.93e-01 | 96.8% | 50.9% |
| 3849233 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.69 | 63.0 | 5.12e-01 | 98.4% | 55.9% |
| 3964581 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.69 | 62.0 | 5.07e-01 | 96.8% | 55.7% |
| 3471323 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.69 | 65.0 | 5.22e-01 | 98.4% | 56.4% |
| 3249533 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 58.0 | 4.32e-01 | 90.4% | 38.1% |
| 4356484 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.68 | 58.0 | 4.86e-01 | 91.2% | 93.8% |
| 3903091 | 277.1.1.0 ↗ | a+b two layers › PX domain › PX domain › PX domain | 0.68 | 56.0 | 3.90e-01 | 87.2% | 53.6% |
| 3973510 | 601.4.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › HBM | 0.68 | 55.0 | 5.48e-01 | 93.6% | 82.3% |
| 4509435 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.68 | 56.0 | 5.12e-01 | 90.4% | 68.1% |
| 3253938 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.68 | 56.0 | 5.85e-01 | 90.4% | 94.8% |
| 3737723 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.67 | 54.0 | 4.53e-01 | 84.8% | 94.3% |
| 3585044 | 601.1.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › VBS | 0.67 | 59.0 | 5.48e-01 | 93.6% | 76.8% |
| 4941651 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.67 | 55.0 | 4.69e-01 | 87.2% | 92.5% |
| 4458487 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.67 | 53.0 | 4.42e-01 | 84.8% | 78.2% |
| 3655293 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.67 | 53.0 | 4.49e-01 | 84.0% | 96.1% |
| 4056675 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.67 | 61.0 | 5.08e-01 | 100.0% | 76.3% |
| 3914657 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 53.0 | 4.47e-01 | 84.8% | 81.9% |
| 3253931 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 60.0 | 5.57e-01 | 96.8% | 88.4% |
| 3445405 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 55.0 | 5.60e-01 | 96.8% | 90.8% |
| 3251835 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.66 | 55.0 | 5.10e-01 | 90.4% | 71.0% |
| 3969777 | 601.1.1.89 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC | 0.66 | 57.0 | 5.22e-01 | 92.0% | 96.2% |
| 5082391 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.66 | 57.0 | 4.83e-01 | 92.0% | 95.0% |
| 3390912 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.66 | 60.0 | 4.82e-01 | 95.2% | 54.2% |
| 3478838 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.66 | 51.0 | 3.91e-01 | 82.4% | 75.1% |
| 3251535 | 601.1.1.95 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › F_actin_bind | 0.66 | 58.0 | 5.19e-01 | 94.4% | 82.4% |
| 3263613 | 601.1.1.97 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B | 0.66 | 56.0 | 5.20e-01 | 91.2% | 78.1% |
| 3910532 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.66 | 55.0 | 5.51e-01 | 88.8% | 92.0% |
| 3851394 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.65 | 56.0 | 5.53e-01 | 92.0% | 88.5% |
| 3579460 | 601.1.3.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › TLN1-like_RS | 0.65 | 56.0 | 5.12e-01 | 93.6% | 69.7% |
| 3517672 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.65 | 55.0 | 5.15e-01 | 93.6% | 74.7% |
| 2841860 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.65 | 53.0 | 5.10e-01 | 88.8% | 75.5% |
| 3478731 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.65 | 59.0 | 5.09e-01 | 96.0% | 65.4% |
| 4541467 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.65 | 53.0 | 4.67e-01 | 86.4% | 83.9% |
| 3944081 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 56.0 | 5.00e-01 | 93.6% | 66.9% |
| 3735641 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.65 | 59.0 | 4.53e-01 | 100.0% | 87.5% |
| 4589931 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.65 | 52.0 | 4.04e-01 | 86.4% | 81.0% |
| 4011437 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 59.0 | 4.69e-01 | 100.0% | 80.0% |
| 3980685 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.64 | 58.0 | 4.75e-01 | 96.0% | 55.8% |
| 3932987 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.64 | 52.0 | 4.07e-01 | 87.2% | 78.1% |
| 3634705 | 601.1.2.50 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GIT1_C | 0.63 | 56.0 | 5.39e-01 | 93.6% | 87.9% |
| 3990526 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.63 | 52.0 | 4.25e-01 | 88.0% | 71.3% |
| 3453619 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.63 | 55.0 | 5.16e-01 | 94.4% | 83.2% |
| 4987042 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 54.0 | 5.29e-01 | 94.4% | 89.6% |
| 3232199 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.62 | 52.0 | 3.99e-01 | 88.0% | 75.9% |
| 3219872 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.62 | 53.0 | 5.14e-01 | 91.2% | 91.4% |
| 3975940 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.62 | 48.0 | 4.53e-01 | 80.8% | 74.0% |
| 4988447 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 49.0 | 5.08e-01 | 88.8% | 89.6% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 55.0 | 5.34e-01 | 96.8% | 90.0% |
| 5047417 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 53.0 | 5.29e-01 | 97.6% | 89.2% |
| 4593081 | 601.1.2.139 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30710 | 0.62 | 56.0 | 5.31e-01 | 97.6% | 86.2% |
| 3202451 | 3567.1.1.51 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin | 0.62 | 55.0 | 4.73e-01 | 96.0% | 88.9% |
| 3672657 | 3755.4.1.23 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7032 | 0.61 | 50.0 | 4.69e-01 | 87.2% | 71.3% |
| 5020411 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 55.0 | 5.18e-01 | 98.4% | 80.0% |
| 3910430 | 611.8.1.1 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne | 0.61 | 50.0 | 4.60e-01 | 87.2% | 83.0% |
| 3224085 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.61 | 55.0 | 4.18e-01 | 100.0% | 89.8% |
| 2396196 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.61 | 54.0 | 5.36e-01 | 97.6% | 91.7% |
| 3168919 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.61 | 48.0 | 3.75e-01 | 85.6% | 77.9% |
| 3698208 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.61 | 50.0 | 4.86e-01 | 87.2% | 83.6% |
| 4011946 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 54.0 | 5.31e-01 | 96.0% | 90.4% |
| 5047771 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 51.0 | 5.35e-01 | 97.6% | 100.0% |
| 3477034 | 192.29.1.188 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › F_actin_bind | 0.60 | 49.0 | 5.02e-01 | 96.8% | 92.5% |
| 5061312 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.59 | 53.0 | 4.80e-01 | 96.0% | 80.6% |
| 4501305 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.59 | 49.0 | 4.56e-01 | 90.4% | 73.1% |
| 3583786 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.59 | 50.0 | 5.08e-01 | 92.8% | 91.2% |
| 4664275 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.58 | 52.0 | 4.40e-01 | 97.6% | 66.8% |
| 3409829 | 604.1.1.16 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PEX11 | 0.58 | 50.0 | 4.15e-01 | 92.0% | 100.0% |
| 3779631 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.58 | 48.0 | 4.09e-01 | 88.8% | 74.0% |
| 3762384 | 601.16.1.9 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › PF31076 | 0.57 | 52.0 | 4.92e-01 | 97.6% | 84.1% |
| 5072346 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.57 | 49.0 | 4.19e-01 | 100.0% | 58.5% |
| 3965080 | 601.4.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PilJ | 0.57 | 44.0 | 4.67e-01 | 93.6% | 94.5% |
| 3817864 | 7016.1.1.0 ↗ | extended segments › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain | 0.57 | 43.0 | 4.19e-01 | 79.2% | 75.6% |
| 3456909 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.57 | 46.0 | 4.84e-01 | 85.6% | 93.0% |
| 3551506 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.56 | 44.0 | 3.37e-01 | 84.8% | 78.0% |
| 3589851 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 45.0 | 4.70e-01 | 86.4% | 96.5% |
| 1291200 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.55 | 45.0 | 3.43e-01 | 87.2% | 80.3% |
| 4591574 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 45.0 | 4.65e-01 | 88.8% | 94.8% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 45.0 | 4.66e-01 | 90.4% | 92.5% |
| 4664272 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.53 | 43.0 | 4.51e-01 | 88.0% | 93.9% |
| 4390628 | 5068.1.1.1 ↗ | alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C | 0.53 | 42.0 | 3.83e-01 | 82.4% | 66.9% |
| 3350509 | 5068.1.1.1 ↗ | alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C | 0.52 | 41.0 | 3.72e-01 | 82.4% | 64.8% |
| 4095116 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.51 | 40.0 | 4.17e-01 | 84.8% | 93.9% |