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membrane_protein_US21
Euk-VirCynomolgus_macaque_cytomegalovirus_strain_Ottawa
membrane_protein_US21__YP_004933979__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969
Identity
- Accession:
- YP_004933979 ↗
- Protein ID:
- membrane_protein_US21
- Kingdom:
- euk
Quality
67.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cynomolgus_macaque_cytomegalovirus_strain_Ottawa
TaxID: 944969
Cluster
View cluster (21 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-100
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 40.0 | 3.99e-01 | 95.0% | 50.0% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.72 | 38.0 | 4.31e-01 | 94.0% | 67.6% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 37.0 | 3.69e-01 | 95.0% | 53.9% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 46.0 | 3.44e-01 | 82.0% | 97.6% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 42.0 | 3.38e-01 | 74.0% | 71.4% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 34.0 | 3.41e-01 | 88.0% | 56.4% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 44.0 | 4.77e-01 | 91.0% | 96.5% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.57 | 46.0 | 4.23e-01 | 87.0% | 75.2% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.56 | 48.0 | 4.22e-01 | 91.0% | 91.6% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 44.0 | 3.69e-01 | 97.0% | 50.9% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 44.0 | 3.24e-01 | 86.0% | 97.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 47.0 | 4.04e-01 | 93.0% | 90.4% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.54 | 47.0 | 3.99e-01 | 95.0% | 90.1% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.54 | 48.0 | 3.03e-01 | 95.0% | 56.8% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.54 | 41.0 | 3.98e-01 | 85.0% | 89.7% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.53 | 47.0 | 3.16e-01 | 96.0% | 65.4% |
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.52 | 43.0 | 3.68e-01 | 90.0% | 76.7% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3477962 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.73 | 61.0 | 6.41e-01 | 88.0% | 100.0% |
| 4676221 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.72 | 60.0 | 4.94e-01 | 92.0% | 52.7% |
| 3988301 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.69 | 57.0 | 4.54e-01 | 90.0% | 45.9% |
| 5065994 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 54.0 | 4.33e-01 | 84.0% | 73.0% |
| 3772719 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.66 | 52.0 | 3.82e-01 | 85.0% | 46.4% |
| 3471400 | 5050.1.1.31 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr | 0.65 | 54.0 | 4.45e-01 | 93.0% | 71.6% |
| 3479676 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 50.0 | 4.21e-01 | 87.0% | 48.9% |
| 3393030 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.63 | 54.0 | 4.14e-01 | 93.0% | 56.1% |
| 3736340 | 622.1.1.7 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › DUF7607 | 0.63 | 52.0 | 5.04e-01 | 91.0% | 90.4% |
| 3697268 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.61 | 41.0 | 3.93e-01 | 73.0% | 58.3% |
| 1388665 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.55 | 47.0 | 2.97e-01 | 90.0% | 58.8% |
| 3838701 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.55 | 49.0 | 3.17e-01 | 95.0% | 62.7% |
| 4024385 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.54 | 47.0 | 4.17e-01 | 95.0% | 80.0% |
| 3650037 | 604.1.1.127 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 | 0.54 | 49.0 | 4.58e-01 | 100.0% | 86.4% |
| 4681325 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.54 | 39.0 | 4.36e-01 | 82.0% | 96.2% |
| 3228061 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.54 | 39.0 | 3.62e-01 | 76.0% | 90.6% |
| 3477521 | 3456.1.1.3 ↗ | extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › OPA1_C | 0.53 | 35.0 | 3.27e-01 | 73.0% | 51.5% |
| 5010020 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.53 | 39.0 | 3.78e-01 | 77.0% | 67.0% |
| 4255370 | 6130.1.1.1 ↗ | alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Se-cys_synth_N | 0.53 | 32.0 | 3.65e-01 | 75.0% | 84.3% |
| 3242139 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.52 | 43.0 | 3.69e-01 | 87.0% | 58.0% |
| 3968185 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.51 | 43.0 | 2.81e-01 | 91.0% | 62.5% |
| 5041273 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 40.0 | 3.95e-01 | 84.0% | 85.7% |
| 3598036 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.50 | 39.0 | 3.45e-01 | 82.0% | 79.3% |
| 3263098 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.50 | 40.0 | 4.07e-01 | 88.0% | 85.0% |
| 3506968 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.50 | 42.0 | 4.02e-01 | 95.0% | 76.7% |
D2
medium
residues 101-219