←Back to structures
membrane_protein_US28
Euk-VirCynomolgus_macaque_cytomegalovirus_strain_Ottawa
membrane_protein_US28__YP_004933996__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969
Identity
- Accession:
- YP_004933996 ↗
- Protein ID:
- membrane_protein_US28
- Kingdom:
- euk
Quality
64.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cynomolgus_macaque_cytomegalovirus_strain_Ottawa
TaxID: 944969
Cluster
View cluster (110 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 149-239
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00001.27 best | 7tm_1 | 45.7 | 8.20e-12 | 69.2% | 25.4% |
CATH (55)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.93 | 89.0 | 5.70e-01 | 100.0% | 26.0% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.82 | 75.0 | 5.07e-01 | 97.8% | 30.5% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.79 | 62.0 | 5.69e-01 | 82.4% | 66.4% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.79 | 57.0 | 5.44e-01 | 74.7% | 76.7% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.78 | 59.0 | 5.52e-01 | 79.1% | 70.0% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 58.0 | 5.59e-01 | 78.0% | 73.1% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 58.0 | 5.10e-01 | 82.4% | 55.5% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 53.0 | 6.06e-01 | 71.4% | 100.0% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 61.0 | 5.78e-01 | 84.6% | 77.1% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 54.0 | 5.50e-01 | 75.8% | 73.6% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.77 | 57.0 | 6.10e-01 | 78.0% | 97.4% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 55.0 | 5.40e-01 | 75.8% | 79.8% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.76 | 63.0 | 4.94e-01 | 96.7% | 44.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 53.0 | 5.82e-01 | 78.0% | 94.4% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.75 | 55.0 | 5.22e-01 | 76.9% | 67.9% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 55.0 | 4.41e-01 | 76.9% | 63.6% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.75 | 53.0 | 5.82e-01 | 73.6% | 95.8% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.75 | 57.0 | 4.71e-01 | 81.3% | 70.8% |
| 3ajwA00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 55.0 | 4.84e-01 | 78.0% | 76.1% |
| 7sf7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 65.0 | 4.57e-01 | 100.0% | 32.5% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 55.0 | 5.51e-01 | 81.3% | 88.3% |
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.71 | 61.0 | 4.93e-01 | 93.4% | 81.4% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 63.0 | 4.41e-01 | 95.6% | 76.7% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 61.0 | 4.98e-01 | 94.5% | 59.0% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.70 | 49.0 | 4.69e-01 | 86.8% | 63.7% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.70 | 57.0 | 5.12e-01 | 100.0% | 64.2% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 51.0 | 5.47e-01 | 78.0% | 93.6% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.70 | 52.0 | 5.46e-01 | 79.1% | 88.7% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 51.0 | 4.78e-01 | 89.0% | 65.1% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 59.0 | 4.68e-01 | 94.5% | 85.1% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 60.0 | 4.40e-01 | 95.6% | 75.0% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 55.0 | 4.57e-01 | 91.2% | 52.1% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 53.0 | 4.55e-01 | 87.9% | 56.0% |
| 3teqB00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 48.0 | 4.64e-01 | 75.8% | 89.1% |
| 4ocqA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.66 | 47.0 | 3.41e-01 | 73.6% | 33.3% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.65 | 58.0 | 4.89e-01 | 94.5% | 79.7% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.65 | 53.0 | 4.65e-01 | 89.0% | 62.8% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.65 | 54.0 | 4.95e-01 | 92.3% | 74.8% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 47.0 | 4.98e-01 | 76.9% | 93.6% |
| 3ukmA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 56.0 | 4.08e-01 | 96.7% | 77.0% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 54.0 | 4.98e-01 | 93.4% | 71.8% |
| 7nc3F01 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.64 | 48.0 | 4.48e-01 | 80.2% | 82.5% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.64 | 42.0 | 4.12e-01 | 96.7% | 62.0% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 56.0 | 3.92e-01 | 94.5% | 74.2% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.63 | 54.0 | 4.28e-01 | 94.5% | 85.9% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 45.0 | 4.49e-01 | 79.1% | 72.4% |
| 3etvA01 | 1.10.287.3290 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 46.0 | 4.81e-01 | 81.3% | 91.7% |
| 3hwcA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 52.0 | 3.94e-01 | 93.4% | 42.9% |
| 3c8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 48.0 | 4.03e-01 | 86.8% | 66.2% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 45.0 | 4.19e-01 | 79.1% | 72.3% |
| 4exjA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 45.0 | 4.17e-01 | 85.7% | 86.0% |
| 5fhiA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 44.0 | 3.84e-01 | 86.8% | 71.9% |
| 1cpcB00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.54 | 47.0 | 3.90e-01 | 100.0% | 86.0% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 30.0 | 3.18e-01 | 74.7% | 61.3% |
| 4f0uA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.52 | 45.0 | 3.83e-01 | 100.0% | 56.9% |
ECOD (65)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4813312 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.95 | 81.0 | 6.54e-01 | 89.0% | 51.6% |
| 4854872 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.92 | 80.0 | 6.06e-01 | 91.2% | 44.3% |
| 2582657 | 601.2.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › 7tm_1 | 0.91 | 86.0 | 7.72e-01 | 100.0% | 77.5% |
| 3753321 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 86.0 | 5.64e-01 | 100.0% | 28.2% |
| 3879274 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 80.0 | 5.98e-01 | 94.5% | 42.9% |
| 4594246 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 85.0 | 5.65e-01 | 100.0% | 29.5% |
| 4259017 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 81.0 | 5.76e-01 | 95.6% | 37.1% |
| 2526901 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 80.0 | 5.99e-01 | 94.5% | 43.2% |
| 3917394 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 84.0 | 5.59e-01 | 100.0% | 29.7% |
| 3559466 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 83.0 | 5.53e-01 | 98.9% | 29.5% |
| 4294577 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 83.0 | 5.49e-01 | 98.9% | 29.2% |
| 3900175 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 78.0 | 5.23e-01 | 94.5% | 27.7% |
| None | — | 0.88 | 80.0 | 5.33e-01 | 95.6% | 28.5% | |
| 4304240 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 83.0 | 5.45e-01 | 98.9% | 28.1% |
| 3573258 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.87 | 79.0 | 5.28e-01 | 96.7% | 27.9% |
| 3890622 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.87 | 82.0 | 5.32e-01 | 100.0% | 26.4% |
| 4422597 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.87 | 82.0 | 5.43e-01 | 100.0% | 30.9% |
| 4174496 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.86 | 81.0 | 6.38e-01 | 100.0% | 52.0% |
| 3766937 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.86 | 81.0 | 5.35e-01 | 100.0% | 31.7% |
| 1931178 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.85 | 75.0 | 6.25e-01 | 100.0% | 57.4% |
| 3883919 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.85 | 80.0 | 5.27e-01 | 100.0% | 30.7% |
| 3772175 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.85 | 79.0 | 5.25e-01 | 100.0% | 28.9% |
| 3909510 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.85 | 79.0 | 5.17e-01 | 100.0% | 32.3% |
| 3582594 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.84 | 76.0 | 5.62e-01 | 96.7% | 44.7% |
| 3361164 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.81 | 63.0 | 4.75e-01 | 82.4% | 40.0% |
| 3239489 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.80 | 70.0 | 4.64e-01 | 94.5% | 27.5% |
| 3754907 | 192.29.1.1 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom | 0.79 | 58.0 | 5.92e-01 | 76.9% | 78.9% |
| 3289986 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.79 | 60.0 | 5.03e-01 | 80.2% | 59.3% |
| 4003429 | 605.1.1.149 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › 7tm_1 | 0.78 | 68.0 | 6.30e-01 | 94.5% | 76.5% |
| 3997950 | 5069.1.3.56 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › GOST_TM | 0.78 | 65.0 | 6.62e-01 | 91.2% | 91.1% |
| 3337008 | 192.2.1.60 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th | 0.78 | 60.0 | 5.11e-01 | 80.2% | 55.7% |
| 3969942 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.77 | 58.0 | 5.37e-01 | 82.4% | 62.6% |
| 3243362 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.77 | 71.0 | 4.71e-01 | 100.0% | 30.1% |
| 3318812 | 192.8.1.248 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th | 0.76 | 59.0 | 4.90e-01 | 80.2% | 52.0% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.76 | 59.0 | 6.10e-01 | 82.4% | 91.8% |
| 4106620 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 54.0 | 5.90e-01 | 75.8% | 93.3% |
| 4340169 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.75 | 54.0 | 4.86e-01 | 74.7% | 87.8% |
| 3655688 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.75 | 59.0 | 4.67e-01 | 82.4% | 45.1% |
| 3267295 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 61.0 | 4.58e-01 | 86.8% | 83.3% |
| 3932516 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.73 | 66.0 | 4.56e-01 | 100.0% | 61.7% |
| 3739377 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.73 | 65.0 | 4.43e-01 | 95.6% | 75.9% |
| 3210948 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.73 | 57.0 | 6.02e-01 | 85.7% | 95.0% |
| 3473220 | 5086.1.1.209 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LIN9_C | 0.72 | 55.0 | 5.09e-01 | 80.2% | 66.1% |
| 3303028 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.71 | 63.0 | 5.29e-01 | 97.8% | 61.9% |
| 3171100 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.70 | 52.0 | 5.07e-01 | 82.4% | 72.0% |
| 4020912 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.70 | 59.0 | 4.21e-01 | 92.3% | 49.1% |
| 3491731 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.70 | 62.0 | 5.44e-01 | 97.8% | 68.9% |
| 3579262 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.70 | 63.0 | 5.04e-01 | 98.9% | 83.4% |
| 4017167 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.69 | 57.0 | 4.06e-01 | 91.2% | 36.4% |
| 3270560 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.69 | 60.0 | 4.35e-01 | 94.5% | 71.0% |
| 3390014 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.68 | 61.0 | 5.13e-01 | 98.9% | 64.0% |
| 3246489 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 59.0 | 4.88e-01 | 100.0% | 80.6% |
| 4398872 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.67 | 57.0 | 4.80e-01 | 95.6% | 54.4% |
| 3422310 | 150.1.1.87 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Erg28 | 0.66 | 52.0 | 4.58e-01 | 91.2% | 57.5% |
| 5054862 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 49.0 | 4.12e-01 | 79.1% | 91.9% |
| 3549992 | 7004.1.1.0 ↗ | 0.66 | 40.0 | 3.78e-01 | 76.9% | 49.5% | |
| 3321745 | 601.1.1.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RPW8 | 0.66 | 53.0 | 4.71e-01 | 89.0% | 62.4% |
| 3495283 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 58.0 | 5.05e-01 | 97.8% | 68.9% |
| 3887929 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.64 | 56.0 | 5.13e-01 | 95.6% | 75.0% |
| 3821611 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 58.0 | 4.57e-01 | 100.0% | 62.8% |
| 3895743 | 3615.1.1.7 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › CD20 | 0.62 | 51.0 | 4.04e-01 | 94.5% | 42.6% |
| 3289545 | 150.8.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE | 0.62 | 54.0 | 4.34e-01 | 100.0% | 95.8% |
| 4562953 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.60 | 47.0 | 3.42e-01 | 86.8% | 62.5% |
| 3571743 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.58 | 51.0 | 4.41e-01 | 94.5% | 68.9% |
| 3535566 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 42.0 | 3.82e-01 | 93.4% | 68.0% |
D2
medium
residues 240-301
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00001.27 best | 7tm_1 | 33.7 | 3.80e-08 | 100.0% | 22.7% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2efeA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.59 | 46.0 | 4.29e-01 | 88.7% | 67.9% |
| 2rt6A00 | 1.20.1270.340 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 45.0 | 3.93e-01 | 93.5% | 87.8% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3349371 | 3922.1.1.140 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Mlo | 0.64 | 53.0 | 5.06e-01 | 96.8% | 80.0% |
| 4445495 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.61 | 39.0 | 3.42e-01 | 71.0% | 41.0% |
D3
medium
residues 302-446
Domain cluster:
rep: envelope_glycoprotein_UL33__NP_783781__Human_herpesvirus_5__10359__D194-311
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00001.27 best | 7tm_1 | 60.5 | 2.60e-16 | 84.1% | 47.7% |