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metalloprotease

Euk-Vir

Western_grey_kangaroopox_virus

metalloprotease__YP_010085184__Western_grey_kangaroopox_virus__1566307

Identity

Accession:
YP_010085184 ↗
Protein ID:
metalloprotease
Kingdom:
euk

Quality

77.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Macropopoxvirus› Western_grey_kangaroopox_virus

TaxID: 1566307

Cluster

View cluster (34 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-189
PDB
Domain cluster: rep: putative_zinc_protease__YP_003986729__Acanthamoeba_polyphaga_mimivirus__212035__D4-209
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03410.20 best Peptidase_M44 341.9 9.70e-102 100.0% 31.3%
D2 high residues 208-373
PDB
Domain cluster: rep: metalloprotease__YP_784262__Nile_crocodilepox_virus__1285600__D203-365
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03410.20 best Peptidase_M44 224.6 3.30e-66 100.0% 27.1%
D3 high residues 407-463
PDB
D4 high residues 473-603
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03410.20 best Peptidase_M44 176.9 9.00e-52 100.0% 21.7%
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.73 42.0 5.35e-01 93.9% 100.0%
3amiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.72 49.0 4.30e-01 70.2% 98.5%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 44.0 5.47e-01 100.0% 100.0%
1sc6A03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 43.0 5.28e-01 96.9% 95.1%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.68 45.0 5.22e-01 99.2% 91.7%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 44.0 5.14e-01 98.5% 92.6%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 43.0 5.23e-01 95.4% 97.7%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.67 42.0 5.20e-01 98.5% 98.8%
2cyyA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.67 42.0 4.87e-01 98.5% 86.3%
2efpA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 42.0 4.82e-01 99.2% 85.7%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 42.0 4.98e-01 100.0% 100.0%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.65 40.0 4.80e-01 98.5% 95.2%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 37.0 4.70e-01 99.2% 98.6%
2p5vA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.65 41.0 4.96e-01 97.7% 98.8%
5d77A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 40.0 4.85e-01 98.5% 100.0%
3o1lB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 42.0 4.88e-01 100.0% 98.9%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 44.0 5.02e-01 100.0% 94.9%
2gqqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.63 40.0 4.89e-01 97.7% 98.8%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.63 41.0 4.75e-01 100.0% 92.5%
2jvrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 39.0 4.73e-01 97.7% 100.0%
2qz8A02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.63 38.0 4.73e-01 97.7% 98.8%
3i4pA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.62 39.0 4.78e-01 97.7% 98.8%
6lpnA04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 42.0 4.89e-01 96.2% 95.8%
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.61 55.0 5.00e-01 98.5% 82.4%
2qrrA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 43.0 4.92e-01 93.9% 100.0%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.59 51.0 4.64e-01 90.8% 92.8%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.58 39.0 4.27e-01 98.5% 82.6%
1s79A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.55 36.0 4.01e-01 98.5% 84.5%
1mhmA00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.55 50.0 4.01e-01 100.0% 81.0%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.53 43.0 4.05e-01 89.3% 89.6%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.51 42.0 3.95e-01 89.3% 88.7%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3600520 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.74 44.0 5.42e-01 93.9% 96.2%
4927807 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.73 44.0 5.43e-01 98.5% 94.1%
3956508 304.162.1.0 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.73 44.0 5.57e-01 97.7% 100.0%
4146821 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.72 42.0 5.21e-01 97.7% 93.8%
5054303 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.72 44.0 5.42e-01 96.9% 100.0%
357856 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.71 44.0 5.20e-01 99.2% 90.9%
5007627 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.71 43.0 5.31e-01 100.0% 98.8%
4165624 304.162.1.0 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.71 44.0 5.36e-01 96.9% 96.5%
4034526 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.71 43.0 5.26e-01 97.7% 98.8%
4978147 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 45.0 5.30e-01 99.2% 93.3%
4931198 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.70 42.0 4.94e-01 96.9% 86.7%
4980062 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 43.0 5.01e-01 98.5% 86.3%
4033758 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.69 42.0 5.16e-01 97.7% 98.8%
5050403 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.69 42.0 5.24e-01 99.2% 100.0%
4534160 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.69 43.0 5.19e-01 99.2% 95.3%
3522051 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 42.0 5.13e-01 95.4% 100.0%
4952685 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 42.0 5.15e-01 98.5% 100.0%
5071313 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.68 41.0 5.01e-01 98.5% 94.0%
4945096 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.67 42.0 4.66e-01 100.0% 79.0%
4954913 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.67 45.0 5.15e-01 98.5% 94.7%
3701330 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.67 46.0 5.05e-01 93.1% 87.6%
4944621 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 43.0 4.42e-01 100.0% 68.0%
5047234 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 44.0 5.02e-01 99.2% 91.6%
4358940 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.66 42.0 5.05e-01 98.5% 98.8%
5260 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.66 43.0 4.88e-01 99.2% 89.5%
3784165 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.66 42.0 4.87e-01 98.5% 92.2%
4156329 304.11.1.4 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › FAS_AT_central 0.65 40.0 4.90e-01 97.7% 100.0%
4043865 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.65 42.0 4.94e-01 99.2% 98.8%
5028338 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 41.0 4.64e-01 100.0% 84.0%
4939641 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.64 39.0 4.83e-01 100.0% 100.0%
4656995 304.9.1.71 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › SNU71_RBD 0.62 45.0 4.56e-01 98.5% 75.4%
3376944 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 42.0 4.67e-01 99.2% 86.7%
3804539 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 45.0 4.84e-01 90.8% 90.0%
5056142 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.61 38.0 4.39e-01 99.2% 87.2%
3648905 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 46.0 4.65e-01 93.1% 79.2%
3617948 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 46.0 5.02e-01 91.6% 98.2%
4059360 304.9.1.71 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › SNU71_RBD 0.58 42.0 4.73e-01 99.2% 99.0%
3790244 304.9.1.40 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › BRAP2 0.55 45.0 4.57e-01 96.2% 87.7%
4796691 2007.1.19.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › SAT 0.54 42.0 4.52e-01 98.5% 98.2%
4948615 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.52 44.0 4.21e-01 90.1% 96.0%
4385553 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.52 44.0 4.09e-01 98.5% 72.7%
3692980 304.9.1.40 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › BRAP2 0.52 45.0 4.48e-01 93.9% 97.0%