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mu-1_protein
Euk-VirMammalian_orthoreovirus_3
mu-1_protein__YP_003199421__Mammalian_orthoreovirus_3__538123
Identity
- Accession:
- YP_003199421 ↗
- Protein ID:
- mu-1_protein
- Kingdom:
- euk
Quality
63.2
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Resentoviricetes›
Reovirales›
Spinareoviridae›
Orthoreovirus›
Mammalian_orthoreovirus_3
TaxID: 538123
Cluster
View cluster (11 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 46-184
D2
high
residues 286-306_531-638
D3
high
residues 309-497
Domain cluster:
rep: VP5__YP_009351853__Fall_chinook_aquareovirus__1963254__D287-475
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05993.18 best | Reovirus_M2 | 213.7 | 5.80e-63 | 100.0% | 28.9% |
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jmuB04 | 2.60.120.420 | Mainly Beta › Sandwich › Jelly Rolls › Membrane penetration protein mu1, Chain B, domain 4 | 0.94 | 91.0 | 8.76e-01 | 98.9% | 91.3% |
| 3iylB03 | 2.60.120.420 | Mainly Beta › Sandwich › Jelly Rolls › Membrane penetration protein mu1, Chain B, domain 4 | 0.87 | 80.0 | 7.44e-01 | 95.8% | 79.2% |
| 3rnsA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.68 | 30.0 | 3.88e-01 | 96.3% | 70.4% |
| 3rnsA02 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.66 | 30.0 | 3.96e-01 | 96.3% | 78.0% |
| 2q1zB02 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.65 | 27.0 | 3.78e-01 | 95.2% | 76.3% |
| 1ex0A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.62 | 35.0 | 4.36e-01 | 88.4% | 89.5% |
| 1l9nA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.60 | 35.0 | 4.27e-01 | 88.4% | 91.2% |
| 2w5fB01 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.60 | 45.0 | 4.96e-01 | 97.4% | 95.4% |
| 1df0A03 | 2.60.120.380 | Mainly Beta › Sandwich › Jelly Rolls › | 0.59 | 41.0 | 4.79e-01 | 95.2% | 100.0% |
| 3lwcA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.59 | 28.0 | 3.61e-01 | 96.3% | 77.7% |
| 8alzB04 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.59 | 33.0 | 4.18e-01 | 88.9% | 91.8% |
| 2x41A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 33.0 | 4.07e-01 | 88.9% | 86.6% |
| 2vvdA00 | 2.60.120.720 | Mainly Beta › Sandwich › Jelly Rolls › | 0.58 | 46.0 | 4.93e-01 | 95.8% | 96.3% |
| 1m06G00 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.57 | 49.0 | 4.95e-01 | 95.2% | 92.0% |
| 5m59A06 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.57 | 32.0 | 3.95e-01 | 88.4% | 89.3% |
| 1jhjA00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.57 | 42.0 | 4.49e-01 | 95.8% | 88.2% |
| 6mnjA01 | 2.60.40.1290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.57 | 43.0 | 4.64e-01 | 87.3% | 94.2% |
| 2wnoA01 | 2.60.120.290 | Mainly Beta › Sandwich › Jelly Rolls › Spermadhesin, CUB domain | 0.57 | 34.0 | 4.20e-01 | 96.8% | 96.5% |
| 2okxA02 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.56 | 41.0 | 4.31e-01 | 95.8% | 82.4% |
| 1xzwA01 | 2.60.40.380 | Mainly Beta › Sandwich › Immunoglobulin-like › Purple acid phosphatase-like, N-terminal | 0.55 | 29.0 | 3.78e-01 | 93.1% | 93.9% |
| 1djxA03 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.55 | 37.0 | 4.40e-01 | 100.0% | 98.5% |
| 2xskA00 | 2.60.40.2420 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.55 | 27.0 | 3.62e-01 | 87.8% | 89.5% |
| 4b60A02 | 2.60.40.1290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 39.0 | 4.25e-01 | 90.5% | 89.1% |
| 2bbaA00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.54 | 47.0 | 4.78e-01 | 97.4% | 95.7% |
| 2ep6A01 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.54 | 34.0 | 4.14e-01 | 99.5% | 98.4% |
| 1fx5B00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 48.0 | 4.51e-01 | 99.5% | 98.3% |
| 4wqmA02 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.53 | 30.0 | 3.81e-01 | 96.3% | 100.0% |
| 3tcaA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 27.0 | 3.62e-01 | 84.7% | 97.8% |
| 4lhsA01 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.53 | 38.0 | 4.25e-01 | 95.8% | 94.6% |
| 2eigA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 47.0 | 4.43e-01 | 97.9% | 97.8% |
| 2y26A02 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 38.0 | 4.12e-01 | 95.8% | 88.9% |
| 6qdiA02 | 3.90.182.10 | Alpha Beta › Alpha-Beta Complex › Toxin - Anthrax Protective Antigen; domain 1 › Toxin - Anthrax Protective Antigen;domain 1 | 0.52 | 35.0 | 4.06e-01 | 94.2% | 95.6% |
| 4bcuA00 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.51 | 43.0 | 4.36e-01 | 98.4% | 89.9% |
| 6kxkB02 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.51 | 35.0 | 4.01e-01 | 100.0% | 97.0% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2794422 | 10.16.1.1 ↗ | beta sandwiches › jelly-roll › Jelly-roll domain in membrane penetration protein mu1 › Jelly-roll domain in membrane penetration protein mu1 › Reovirus_M2 | 0.94 | 90.0 | 8.43e-01 | 98.4% | 84.8% |
| 1124176 | 10.16.1.1 ↗ | beta sandwiches › jelly-roll › Jelly-roll domain in membrane penetration protein mu1 › Jelly-roll domain in membrane penetration protein mu1 › Reovirus_M2 | 0.87 | 80.0 | 8.15e-01 | 95.8% | 97.3% |
| 3272798 | 10.32.1.3 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Calpain_III | 0.61 | 42.0 | 4.85e-01 | 95.8% | 97.8% |
| 3881289 | 10.3.1.1 ↗ | beta sandwiches › jelly-roll › TNF-like › TNF-like › TNF | 0.59 | 44.0 | 4.79e-01 | 97.9% | 91.8% |
| 3407663 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.59 | 43.0 | 4.89e-01 | 95.8% | 98.6% |
| 1137922 | 11.1.1.7 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › A2M,A2M_BRD | 0.58 | 30.0 | 3.91e-01 | 86.8% | 89.2% |
| 1852013 | 11.1.5.40 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › BNR_assoc_N | 0.57 | 44.0 | 4.61e-01 | 97.4% | 88.7% |
| 3741738 | 10.2.1.55 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › NPL | 0.57 | 37.0 | 4.41e-01 | 98.4% | 98.4% |
| 4362871 | 10.2.1.86 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › But2 | 0.56 | 45.0 | 4.84e-01 | 94.7% | 99.4% |
| 3703952 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 32.0 | 3.94e-01 | 94.7% | 91.8% |
| 3246669 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.56 | 38.0 | 4.30e-01 | 94.7% | 92.1% |
| 5039918 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.56 | 37.0 | 4.19e-01 | 95.2% | 90.0% |
| 3213588 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.56 | 36.0 | 4.23e-01 | 94.7% | 91.9% |
| 3500088 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 41.0 | 4.35e-01 | 92.1% | 88.5% |
| 3250775 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.55 | 37.0 | 4.38e-01 | 100.0% | 100.0% |
| 3249011 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.55 | 37.0 | 4.29e-01 | 98.9% | 92.9% |
| 3273223 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.55 | 37.0 | 4.24e-01 | 93.1% | 92.8% |
| 3267026 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.55 | 34.0 | 4.17e-01 | 88.9% | 97.5% |
| 3168473 | 10.32.1.306 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PF30096 | 0.54 | 48.0 | 4.86e-01 | 97.4% | 95.8% |
| 4054976 | 10.2.1.75 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › CBM96 | 0.54 | 44.0 | 4.73e-01 | 93.7% | 99.4% |
| 3659663 | 10.32.1.37 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Malectin | 0.54 | 42.0 | 4.45e-01 | 97.9% | 90.6% |
| 3762739 | 10.4.1.1 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › CUB | 0.54 | 32.0 | 3.91e-01 | 97.4% | 91.7% |
| 3718771 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.54 | 35.0 | 3.91e-01 | 99.5% | 82.7% |
| 3609230 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.53 | 39.0 | 4.35e-01 | 100.0% | 96.6% |
| 3351346 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.53 | 41.0 | 4.45e-01 | 98.9% | 96.8% |
| 3357481 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.53 | 48.0 | 3.44e-01 | 99.5% | 41.2% |
| 3407300 | 10.32.1.5 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Ephrin_lbd | 0.52 | 45.0 | 4.64e-01 | 95.8% | 97.8% |
| 4019267 | 10.1.1.36 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Polysacc_lyase | 0.52 | 48.0 | 4.43e-01 | 100.0% | 96.2% |
| 3901027 | 11.2.1.53 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_CAPS | 0.52 | 34.0 | 4.01e-01 | 100.0% | 95.4% |
| 4017488 | 11.1.1.498 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LDB19 | 0.52 | 38.0 | 4.13e-01 | 95.2% | 91.0% |
| 3621449 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.52 | 35.0 | 4.03e-01 | 99.5% | 93.6% |
| 3639340 | 11.1.1.498 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LDB19 | 0.52 | 38.0 | 4.07e-01 | 94.7% | 88.1% |
| 3615742 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.51 | 36.0 | 4.07e-01 | 98.9% | 92.4% |
| 3680135 | 10.1.1.2 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB | 0.51 | 46.0 | 4.13e-01 | 98.9% | 97.0% |
| 1158353 | 10.32.1.30 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › NPCBM | 0.51 | 42.0 | 4.35e-01 | 96.3% | 92.3% |
| 3595385 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.51 | 39.0 | 4.20e-01 | 89.9% | 94.4% |
| 3597124 | 10.15.1.1 ↗ | beta sandwiches › jelly-roll › Smp-1-like › Smp-1-like › DUF1935 | 0.50 | 33.0 | 3.86e-01 | 97.4% | 94.6% |
| 3881235 | 11.1.1.206 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IL17R_fnIII_D1 | 0.50 | 34.0 | 3.59e-01 | 73.0% | 75.3% |
| 3741869 | 11.1.1.498 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LDB19 | 0.50 | 38.0 | 4.11e-01 | 94.7% | 91.9% |
| 3257602 | 11.2.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 | 0.50 | 35.0 | 4.03e-01 | 97.9% | 97.8% |
| 3553055 | 10.32.1.196 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › WLS_GOLD | 0.50 | 44.0 | 4.52e-01 | 95.8% | 100.0% |
D4
medium
residues 185-269