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mu_NS

Euk-Vir

Mahlapitsi_orthoreovirus

mu_NS__YP_009246468__Mahlapitsi_orthoreovirus__2170064

Identity

Accession:
YP_009246468 ↗
Protein ID:
mu_NS
Kingdom:
euk

Quality

65.7 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Spinareoviridae› Orthoreovirus› Mahlapitsi_orthoreovirus

TaxID: 2170064

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 60-158
PDB
Domain cluster: rep: nonstructural_protein__YP_009110700__Cangyuan_orthoreovirus__1388882__D42-136
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hoxA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 43.0 3.38e-01 73.7% 96.2%
4msxA02 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 47.0 3.41e-01 93.9% 42.4%
3bk2A03 3.10.20.580 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.53 37.0 3.70e-01 87.9% 70.7%
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.52 41.0 2.89e-01 87.9% 100.0%
1bqbA01 3.10.170.10 Alpha Beta › Roll › Elastase; domain 1 › 0.51 40.0 3.59e-01 87.9% 81.2%
6tmfI00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.51 43.0 3.50e-01 100.0% 86.4%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4968008 230.6.1.1 ↗ a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.57 41.0 4.09e-01 86.9% 71.4%
4468322 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.56 36.0 3.67e-01 85.9% 65.0%
4988943 230.6.1.1 ↗ a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.53 39.0 3.78e-01 86.9% 70.0%
3284467 601.7.1.34 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 0.51 42.0 4.12e-01 89.9% 99.0%
3707303 2498.1.1.14 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M8 0.50 43.0 2.88e-01 100.0% 32.1%
D2 high residues 247-391
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3n75A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 40.0 4.23e-01 89.0% 74.4%
3u7rA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.59 49.0 4.54e-01 89.0% 72.5%
7mi4A02 3.100.10.20 Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › CRISPR-associated endonuclease Cas1, N-terminal domain 0.58 28.0 3.83e-01 87.6% 90.5%
6k8nA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 47.0 4.63e-01 89.0% 99.4%
6dqoA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.57 47.0 4.46e-01 89.0% 74.0%
4dcuA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 41.0 4.18e-01 88.3% 78.6%
2x7xA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 43.0 4.50e-01 80.7% 99.2%
2yvaA00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 43.0 3.98e-01 97.2% 63.7%
6w6aA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 41.0 3.49e-01 82.1% 96.8%
3q71A00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 47.0 4.25e-01 98.6% 81.3%
2xblD00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 42.0 3.86e-01 97.9% 63.6%
2p90A01 3.40.50.10900 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit 0.53 43.0 3.75e-01 87.6% 93.3%
1dgmA01 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.52 42.0 3.45e-01 85.5% 95.7%
1cw1A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.52 43.0 3.14e-01 89.0% 88.7%
5zx8A00 3.40.50.1470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase 0.52 40.0 3.69e-01 81.4% 96.2%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.51 30.0 3.07e-01 90.3% 57.6%
1zswA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.51 31.0 3.15e-01 91.0% 58.7%
1l7eA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 44.0 4.16e-01 96.6% 83.1%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988822 211.1.1.1 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.63 28.0 4.18e-01 77.2% 95.4%
3625722 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.60 27.0 3.91e-01 71.0% 100.0%
5020060 2003.1.1.50 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DUF364 0.58 41.0 3.96e-01 97.2% 64.4%
4025017 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 51.0 4.18e-01 95.2% 75.1%
3740687 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 50.0 3.82e-01 92.4% 85.5%
4527732 2007.2.1.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › FMN_red 0.58 48.0 4.32e-01 89.0% 65.6%
4024204 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.57 49.0 4.01e-01 94.5% 85.8%
4003996 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.57 45.0 3.80e-01 83.4% 81.7%
3510497 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.56 50.0 4.15e-01 96.6% 89.0%
3604222 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.56 40.0 4.53e-01 83.4% 98.2%
3214660 2007.25.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domain in Ribosomal protein L1 › Rossmann-like domain in Ribosomal protein L1 › Ribosomal_L1 0.56 42.0 4.55e-01 87.6% 92.0%
3690976 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 48.0 4.05e-01 95.9% 72.9%
3889205 2004.1.1.118 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.56 46.0 4.20e-01 89.7% 76.8%
4934622 2003.1.1.50 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DUF364 0.55 39.0 3.84e-01 98.6% 67.1%
3498423 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.55 42.0 2.96e-01 81.4% 68.1%
5015826 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.55 46.0 4.06e-01 91.0% 84.5%
3938607 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.55 42.0 2.75e-01 81.4% 49.8%
None — 0.54 43.0 3.96e-01 97.2% 63.4%
3846940 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.54 40.0 2.96e-01 76.6% 82.1%
3199898 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 45.0 4.00e-01 89.7% 71.9%
3599933 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 39.0 2.93e-01 76.6% 78.2%
4998914 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 39.0 3.46e-01 77.9% 96.8%
5001397 316.1.1.41 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF6036 0.52 33.0 2.93e-01 94.5% 43.4%
3703913 7529.1.1.0 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like 0.51 43.0 4.28e-01 89.7% 94.7%
5081670 2004.1.1.99 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N 0.51 42.0 3.79e-01 97.9% 62.4%
2897753 220.1.1.10 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › SSrecog 0.51 27.0 3.53e-01 86.2% 94.8%
None — 0.51 44.0 3.39e-01 99.3% 70.0%
4306159 2011.2.1.3 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro 0.51 42.0 3.89e-01 90.3% 97.9%
None — 0.50 44.0 3.13e-01 98.6% 67.2%
3702133 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.50 38.0 2.92e-01 82.1% 96.3%
4980836 7574.1.1.0 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.50 44.0 3.40e-01 95.9% 53.2%
4016425 7590.1.1.2 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.50 40.0 3.69e-01 85.5% 77.4%