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multifunctional_expression_regulator

Euk-Vir

Psittacid_alphaherpesvirus_1

multifunctional_expression_regulator__NP_944380__Psittacid_alphaherpesvirus_1__50294

Identity

Accession:: NP_944380 ↗
Protein ID:: multifunctional_expression_regulator
Kingdom:: euk

Quality

57.5 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Iltovirus› Psittacid_alphaherpesvirus_1

TaxID: 50294

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 392-418_435-474

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4x28C03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	35.0	2.71e-01	71.6%	39.2%

D2 medium residues 475-625

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF05459.19 best	Herpes_UL69	130.2	1.20e-37	100.0%	73.8%

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2j9wB00	1.20.120.1130	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain	0.69	43.0	5.18e-01	84.1%	96.0%
3ezhA00	1.20.120.960	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain	0.60	42.0	4.70e-01	100.0%	95.6%
3terA00	1.10.287.3550	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.58	23.0	2.61e-01	92.1%	43.7%
2hujA00	1.20.120.440	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like	0.57	42.0	4.60e-01	100.0%	93.6%
2np9A01	1.20.58.1300	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	38.0	4.06e-01	70.2%	78.4%
3qsgA02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.55	38.0	4.26e-01	70.2%	100.0%
2jexA01	1.10.287.30	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1	0.54	34.0	4.09e-01	70.9%	97.9%
1dtoA01	1.10.287.30	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1	0.53	35.0	4.16e-01	71.5%	98.0%
3r2kA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.53	37.0	3.71e-01	71.5%	90.3%
1li5A02	1.20.120.640	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.53	30.0	3.83e-01	77.5%	97.7%
2q00B00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.51	39.0	4.23e-01	86.1%	100.0%
6igxD01	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.50	28.0	2.33e-01	85.4%	30.2%

ECOD (14)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1562404	3977.1.1.1 ↗	alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69	0.85	80.0	6.44e-01	100.0%	55.6%
2418879	3977.1.1.1 ↗	alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69	0.71	65.0	5.35e-01	100.0%	60.4%
4947816	601.28.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like	0.65	41.0	4.90e-01	86.1%	95.0%
3788601	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.56	42.0	2.97e-01	79.5%	87.6%
3437287	5086.1.1.199 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF31016	0.55	24.0	2.30e-01	97.4%	32.6%
5058654	601.14.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin	0.53	47.0	4.68e-01	97.4%	96.1%
3260332	5069.1.1.7 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561	0.53	41.0	4.03e-01	86.8%	73.5%
3215766	192.29.1.24 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237	0.52	44.0	4.47e-01	97.4%	92.0%
3212271	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.52	43.0	4.33e-01	88.7%	89.0%
4801290	601.1.2.4 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4	0.52	39.0	3.99e-01	84.1%	81.2%
3437011	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.52	29.0	3.30e-01	70.9%	71.3%
3721451	5069.1.1.7 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561	0.51	40.0	3.85e-01	86.8%	72.9%
3236769	633.23.1.0 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin	0.51	37.0	3.82e-01	96.0%	79.3%
4978790	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.51	32.0	3.66e-01	96.0%	87.0%