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multifunctional_expression_regulator
Euk-VirEquid_gammaherpesvirus_5
multifunctional_expression_regulator__YP_009118447__Equid_gammaherpesvirus_5__10371
Identity
- Accession:
- YP_009118447 ↗
- Protein ID:
- multifunctional_expression_regulator
- Kingdom:
- euk
Quality
61.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Equid_gammaherpesvirus_5
TaxID: 10371
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 412-503
Domain cluster:
rep: ORF57__YP_001129410__Human_gammaherpesvirus_8__37296__D221-304
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 72.4 | 5.80e-20 | 84.8% | 35.5% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3mekA03 | 1.10.220.160 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › | 0.65 | 47.0 | 4.90e-01 | 76.1% | 90.7% |
| 2ongA01 | 1.50.10.130 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain | 0.56 | 44.0 | 3.49e-01 | 100.0% | 39.2% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.55 | 48.0 | 4.39e-01 | 100.0% | 84.3% |
| 2xrhA00 | 1.20.120.1430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HP0721 helical bundle | 0.51 | 43.0 | 4.29e-01 | 100.0% | 91.0% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.51 | 41.0 | 3.11e-01 | 85.9% | 72.4% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.98 | 95.0 | 6.38e-01 | 100.0% | 33.6% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.96 | 92.0 | 6.28e-01 | 100.0% | 34.4% |
| 1562404 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.89 | 82.0 | 5.69e-01 | 100.0% | 33.6% |
| 3432902 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.57 | 40.0 | 3.80e-01 | 75.0% | 90.4% |
| 2700810 | 2005.1.1.31 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CDPS | 0.51 | 45.0 | 3.41e-01 | 100.0% | 46.1% |
D2
medium
residues 504-630
Domain cluster:
rep: transcriptional_control_protein__NP_065556__Alcelaphine_gammaherpesvirus_1__35252__D306-423
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 81.5 | 9.20e-23 | 100.0% | 57.9% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2x3mA00 | 1.25.40.670 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 44.0 | 4.01e-01 | 70.9% | 61.4% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.62 | 35.0 | 3.70e-01 | 92.9% | 60.2% |
| 4cruB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 42.0 | 3.28e-01 | 70.1% | 67.0% |
| 5an3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 43.0 | 4.36e-01 | 81.9% | 93.8% |
| 4dvgB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.56 | 39.0 | 2.96e-01 | 70.9% | 46.9% |
| 4gpkF02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 39.0 | 3.22e-01 | 73.2% | 45.0% |
| 2kckA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 37.0 | 3.98e-01 | 70.9% | 85.7% |
| 4leuA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 37.0 | 3.27e-01 | 70.1% | 60.4% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 40.0 | 4.13e-01 | 100.0% | 84.4% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 35.0 | 3.62e-01 | 86.6% | 73.4% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.91 | 88.0 | 6.57e-01 | 100.0% | 47.3% |
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.91 | 87.0 | 6.47e-01 | 100.0% | 46.1% |
| 3454452 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.58 | 40.0 | 3.63e-01 | 70.1% | 78.2% |
| 3678680 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.58 | 40.0 | 3.67e-01 | 70.9% | 74.7% |
| 3343494 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.57 | 39.0 | 3.56e-01 | 70.1% | 77.1% |
| 3611311 | 109.4.1.765 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fab1_bd | 0.57 | 40.0 | 3.68e-01 | 71.7% | 83.6% |
| 3642331 | 109.4.1.1370 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, XMAP215_CLASP_TOG | 0.57 | 39.0 | 3.92e-01 | 71.7% | 89.6% |
| 3822569 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.55 | 38.0 | 3.86e-01 | 70.9% | 76.0% |
| 3904019 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 40.0 | 3.75e-01 | 78.0% | 87.9% |
| 3806507 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 42.0 | 3.45e-01 | 85.0% | 97.0% |
| 3876854 | 109.4.1.375 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRC8_N | 0.53 | 44.0 | 3.32e-01 | 91.3% | 57.5% |
| 3410251 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 36.0 | 3.29e-01 | 72.4% | 62.2% |
| 3463873 | 3807.1.1.4 ↗ | alpha bundles › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › DUF4220 | 0.52 | 47.0 | 3.78e-01 | 100.0% | 80.4% |
| 3337409 | 109.4.1.1277 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, TPR_24 | 0.51 | 36.0 | 3.59e-01 | 72.4% | 72.6% |
| 3473869 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.51 | 41.0 | 3.85e-01 | 100.0% | 71.0% |
| 4027495 | 109.4.1.68 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Coatomer_E | 0.51 | 44.0 | 3.40e-01 | 92.9% | 67.0% |
| 3842806 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 39.0 | 3.89e-01 | 82.7% | 97.8% |
| 3465253 | 109.4.1.541 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 | 0.50 | 44.0 | 3.14e-01 | 96.1% | 90.3% |