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multifunctional_expression_regulator

Euk-Vir

Testudinid_alphaherpesvirus_3

multifunctional_expression_regulator__YP_009176893__Testudinid_alphaherpesvirus_3__2560801

Identity

Accession:
YP_009176893 ↗
Protein ID:
multifunctional_expression_regulator
Kingdom:
euk

Quality

59.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 219-411
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05459.19 best Herpes_UL69 153.9 6.40e-45 100.0% 91.6%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.69 37.0 4.49e-01 71.0% 78.1%
1i5nB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.66 34.0 4.18e-01 72.0% 75.8%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.62 44.0 4.96e-01 80.3% 96.5%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.60 42.0 4.83e-01 78.8% 99.3%
1rz4A01 1.25.40.250 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1 0.58 29.0 3.59e-01 76.7% 75.0%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 36.0 4.14e-01 90.2% 85.5%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.56 36.0 3.75e-01 77.2% 66.8%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 30.0 3.78e-01 89.1% 85.1%
3mpxA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.56 39.0 3.82e-01 92.7% 65.0%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 34.0 3.92e-01 86.0% 82.3%
2ongA01 1.50.10.130 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain 0.55 33.0 3.28e-01 90.2% 54.4%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 32.0 3.85e-01 91.2% 87.7%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.54 30.0 3.27e-01 90.2% 61.2%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.54 31.0 3.78e-01 77.2% 87.6%
2vpzC00 1.20.1630.10 Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain 0.54 41.0 3.80e-01 79.3% 90.4%
6a2aA01 1.50.10.130 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain 0.54 33.0 3.28e-01 100.0% 56.1%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.53 35.0 3.86e-01 79.8% 82.4%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 40.0 4.05e-01 85.5% 81.1%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1562404 3977.1.1.1 alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 0.88 82.0 7.20e-01 100.0% 69.8%
5031295 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.63 44.0 5.01e-01 71.5% 96.4%
3655099 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.63 30.0 3.13e-01 72.5% 48.0%
3230188 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.61 37.0 4.12e-01 92.7% 76.5%
5056116 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 35.0 3.53e-01 89.1% 57.5%
3517342 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 39.0 4.04e-01 71.5% 73.0%
134489 601.19.1.1 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.56 41.0 4.25e-01 76.2% 83.1%
134174 129.1.1.11 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C 0.55 30.0 3.56e-01 77.7% 77.2%
3205546 601.13.1.3 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › Sin3_corepress 0.55 31.0 3.83e-01 79.8% 88.3%
3252931 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.53 33.0 3.62e-01 88.6% 73.8%
3286424 5069.1.1.57 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PepSY_TM 0.53 42.0 3.84e-01 81.9% 90.8%
5013436 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 39.0 3.72e-01 89.6% 65.9%
3717901 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 37.0 2.70e-01 73.1% 35.4%
5014172 3236.1.1.0 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) 0.51 43.0 3.78e-01 89.6% 91.4%
3625019 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 35.0 3.58e-01 79.3% 69.7%
3925476 109.4.1.1134 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_INTS8_3 0.50 39.0 3.11e-01 82.4% 50.5%