←Back to structures
multifunctional_expression_regulator
Euk-VirWood_mouse_herpesvirus
multifunctional_expression_regulator__YP_010085931__Wood_mouse_herpesvirus__432370
Identity
- Accession:
- YP_010085931 ↗
- Protein ID:
- multifunctional_expression_regulator
- Kingdom:
- euk
Quality
72.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Wood_mouse_herpesvirus
TaxID: 432370
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 180-236_249-259_398-409
Domain cluster:
rep: orf57__YP_009044440__Alcelaphine_gammaherpesvirus_2__138184__D200-256_423-434
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1l5jA01 | 1.25.40.310 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Aconitate B, HEAT-like domain | 0.56 | 43.0 | 3.51e-01 | 85.0% | 62.7% |
| 2qkbA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.51 | 35.0 | 2.87e-01 | 71.2% | 96.7% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.95 | 90.0 | 5.92e-01 | 100.0% | 83.6% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.90 | 84.0 | 5.62e-01 | 100.0% | 86.1% |
| 5044904 | 109.4.1.124 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_alkylation | 0.58 | 46.0 | 3.32e-01 | 85.0% | 30.8% |
| 3191927 | 190.1.1.0 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box | 0.58 | 39.0 | 3.46e-01 | 83.7% | 47.8% |
D2
medium
residues 237-248_260-397
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 84.6 | 1.10e-23 | 100.0% | 66.8% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7wu8B01 | 1.20.1160.20 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › | 0.57 | 32.0 | 4.07e-01 | 73.3% | 100.0% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.56 | 33.0 | 3.41e-01 | 82.0% | 59.2% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 41.0 | 4.12e-01 | 96.7% | 76.5% |
| 1hy5B00 | 1.20.120.260 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain | 0.54 | 38.0 | 4.17e-01 | 90.0% | 89.3% |
| 8b70A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.54 | 46.0 | 3.36e-01 | 92.7% | 86.1% |
| 2yw6B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 39.0 | 3.91e-01 | 96.7% | 76.0% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.53 | 39.0 | 3.43e-01 | 74.7% | 86.5% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 39.0 | 4.24e-01 | 87.3% | 90.6% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 39.0 | 4.18e-01 | 96.7% | 91.3% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 36.0 | 3.90e-01 | 89.3% | 85.2% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.52 | 39.0 | 4.23e-01 | 98.7% | 93.6% |
| 8ex5A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 40.0 | 3.74e-01 | 96.0% | 64.9% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.52 | 47.0 | 4.15e-01 | 100.0% | 75.1% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 38.0 | 3.69e-01 | 96.7% | 66.9% |
| 3u64A00 | 1.25.40.920 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component | 0.51 | 39.0 | 3.27e-01 | 79.3% | 83.4% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.51 | 46.0 | 4.03e-01 | 100.0% | 75.5% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 36.0 | 4.00e-01 | 88.7% | 94.9% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.89 | 84.0 | 6.67e-01 | 100.0% | 58.9% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.88 | 84.0 | 6.69e-01 | 100.0% | 60.8% |
| 5074047 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.56 | 39.0 | 4.31e-01 | 90.7% | 90.0% |
| 5080014 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.55 | 37.0 | 4.14e-01 | 97.3% | 88.7% |
| 3941776 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 38.0 | 3.46e-01 | 90.7% | 52.7% |
| 4417622 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 41.0 | 3.67e-01 | 94.7% | 55.8% |
| 3171367 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 40.0 | 3.42e-01 | 91.3% | 48.6% |
| 3202274 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 40.0 | 3.60e-01 | 92.0% | 56.3% |
| 3731859 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 41.0 | 3.78e-01 | 100.0% | 63.6% |
| 3276285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.52 | 39.0 | 4.22e-01 | 86.0% | 92.8% |
| 3494327 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.52 | 36.0 | 3.42e-01 | 71.3% | 93.0% |
| 3979650 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.72e-01 | 85.3% | 67.4% |
| 3061928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 43.0 | 4.01e-01 | 90.7% | 85.2% |
| 3409782 | 3236.1.1.1 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger | 0.51 | 45.0 | 3.38e-01 | 100.0% | 72.1% |
| 4029793 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 36.0 | 3.49e-01 | 86.0% | 64.0% |