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multifunctional_expression_regulator_transactivator

Euk-Vir

Murine_roseolovirus

multifunctional_expression_regulator_transactivator__YP_009344887__Murine_roseolovirus__1940555

Identity

Accession:
YP_009344887 ↗
Protein ID:
multifunctional_expression_regulator_transactivator
Kingdom:
euk

Quality

65.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Murine_roseolovirus

TaxID: 1940555

Cluster

View cluster (9 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 87-162
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3w3uA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 45.0 2.58e-01 100.0% 24.5%
3zheD01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 37.0 2.77e-01 78.9% 35.6%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3319297 109.4.1.81 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF-3c_N 0.56 41.0 3.06e-01 78.9% 55.1%
3834069 109.4.1.81 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF-3c_N 0.52 39.0 2.56e-01 80.3% 20.3%
D2 medium residues 163-240_300-364
PDB
Domain cluster: rep: multifunctional_expression_regulator__NP_944380__Psittacid_alphaherpesvirus_1__50294__D475-625
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05459.19 best Herpes_UL69 58.5 1.00e-15 55.2% 32.7%
PF05459.19 Herpes_UL69 49.7 5.30e-13 45.5% 29.9%
D3 medium residues 241-299
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5hdiA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.70 53.0 3.17e-01 79.7% 17.9%
7qocA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.62 52.0 3.68e-01 94.9% 44.9%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.61 46.0 4.06e-01 81.4% 81.4%
6tepC02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.61 53.0 3.79e-01 100.0% 38.1%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 48.0 4.72e-01 84.7% 93.5%
3fi9A02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.61 51.0 3.76e-01 100.0% 92.1%
2kvsA00 1.10.150.260 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › YozE SAM-like 0.60 49.0 4.46e-01 91.5% 90.0%
1owlA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 51.0 4.07e-01 98.3% 61.8%
6nbrC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 47.0 3.00e-01 91.5% 17.5%
1vnsA01 1.20.144.10 Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase 0.58 46.0 3.34e-01 89.8% 68.0%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.57 49.0 3.96e-01 96.6% 61.1%
4cs9C00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.57 43.0 3.17e-01 100.0% 30.3%
3nz4B03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.56 42.0 3.62e-01 84.7% 92.3%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.55 45.0 4.01e-01 94.9% 68.2%
8fazD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 44.0 2.97e-01 89.8% 29.0%
3dboB00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.53 40.0 3.13e-01 81.4% 42.9%
3ir4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 40.0 3.22e-01 88.1% 100.0%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3877690 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.67 59.0 5.14e-01 100.0% 70.0%
3925443 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 54.0 4.05e-01 93.2% 38.6%
3741821 109.21.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleopor_Nup85 0.63 51.0 2.89e-01 89.8% 38.3%
3966057 4239.2.1.1 ↗ alpha arrays › DNA polymerase III theta subunit-like › LasR-specific antiactivator (QslA) › LasR-specific antiactivator (QslA) › QslA 0.62 55.0 4.62e-01 96.6% 65.3%
4944773 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.62 54.0 3.96e-01 98.3% 86.9%
5008445 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 53.0 4.84e-01 94.9% 73.3%
3740089 1134.1.1.7 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 0.61 52.0 5.11e-01 93.2% 93.8%
3497830 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.31e-01 100.0% 24.3%
4638111 2004.1.1.483 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, AAA_19, UvrD_C 0.60 48.0 2.64e-01 88.1% 9.3%
4037687 639.2.1.0 ↗ alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.59 52.0 4.92e-01 98.3% 95.7%
4443691 650.1.1.0 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.59 53.0 4.72e-01 96.6% 72.5%
3503701 140.1.1.0 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.58 45.0 3.23e-01 91.5% 28.8%
5068933 101.1.7.0 ↗ alpha arrays › HTH › HTH › Methylated DNA-protein cysteine methyltransferase-C 0.57 52.0 4.64e-01 100.0% 80.0%
3243119 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 37.0 3.45e-01 98.3% 52.5%
3609997 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.55 42.0 2.81e-01 84.7% 62.7%
3814977 650.1.1.0 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.53 47.0 4.15e-01 98.3% 94.1%
3892511 110.1.1.2 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › CARD 0.53 39.0 3.50e-01 79.7% 61.2%
3360995 4958.1.1.1 ↗ a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 0.52 43.0 2.77e-01 91.5% 19.3%
3723686 3621.1.1.0 ↗ alpha arrays › Dipeptidyl-peptidase 2 helical domain › Dipeptidyl-peptidase 2 helical domain › Dipeptidyl-peptidase 2 helical domain 0.51 33.0 2.88e-01 72.9% 40.0%