←Back to structures

neuraminidase

Euk-Vir

Influenza_B_virus_-B_Lee_1940-

neuraminidase__NP_056663__Influenza_B_virus_-B_Lee_1940-__518987

Identity

Accession:
NP_056663 ↗
Protein ID:
neuraminidase
Kingdom:
euk

Quality

48.9 mean pLDDT

Taxonomy

Orthornavirae› Negarnaviricota› Insthoviricetes› Articulavirales› Orthomyxoviridae› Betainfluenzavirus› Influenza_B_virus_(B/Lee/1940)

TaxID: 518987

Cluster

View cluster (61 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 93-108_362-455
PDB
D2 medium residues 109-225
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00064.26 best Neur 175.8 1.50e-51 100.0% 29.6%
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1b9vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.89 84.0 5.58e-01 98.3% 29.5%
1inyA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.86 81.0 5.44e-01 99.1% 29.9%
4k3yC00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.86 71.0 4.89e-01 99.1% 28.5%
4fvkA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.82 75.0 5.12e-01 99.1% 30.8%
3qeeB00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.74 67.0 4.88e-01 97.4% 60.5%
7bj4A01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.73 67.0 4.56e-01 98.3% 59.3%
3o4hA01 2.130.10.150 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Peptidase/esterase 'gauge' domain 0.71 55.0 4.06e-01 97.4% 32.0%
7ne4A01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.71 60.0 4.30e-01 100.0% 32.5%
4mlgG00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.70 63.0 4.53e-01 97.4% 66.7%
2bs6A01 2.40.128.190 Mainly Beta › Beta Barrel › Lipocalin › 0.70 48.0 5.44e-01 85.5% 97.6%
4u6bA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.69 64.0 4.48e-01 100.0% 50.1%
2b4wA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.67 61.0 4.53e-01 99.1% 54.6%
1vyfA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.66 38.0 3.65e-01 90.6% 50.4%
4nehA01 2.130.10.130 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal 0.65 59.0 4.07e-01 99.1% 35.1%
1mdcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.64 37.0 3.59e-01 89.7% 51.9%
2a0aA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.63 37.0 3.56e-01 89.7% 51.1%
1s4uX00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.63 57.0 4.02e-01 98.3% 45.2%
4eqaC00 2.40.128.650 Mainly Beta › Beta Barrel › Lipocalin › 0.62 50.0 4.67e-01 97.4% 68.7%
5c2vB00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.62 54.0 3.85e-01 96.6% 52.0%
4id2A00 2.40.128.510 Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4738 0.61 50.0 4.75e-01 87.2% 92.6%
4csdB00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.61 54.0 4.17e-01 98.3% 44.2%
1v2bB00 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.60 38.0 3.53e-01 85.5% 49.7%
4exrA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 34.0 4.29e-01 82.1% 94.4%
6c1zA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.59 36.0 3.40e-01 89.7% 50.7%
2rcqA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 36.0 3.43e-01 92.3% 50.4%
1ealA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.57 33.0 3.24e-01 90.6% 50.4%
4exrA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 37.0 4.37e-01 83.8% 96.3%
3d4eA01 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.53 32.0 3.81e-01 74.4% 86.9%
1f49A05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.52 38.0 2.88e-01 77.8% 89.3%
2eabB01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.51 43.0 3.50e-01 96.6% 79.8%
3mx7A00 2.40.128.180 Mainly Beta › Beta Barrel › Lipocalin › 0.51 36.0 4.05e-01 96.6% 96.7%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1110926 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.89 74.0 5.04e-01 99.1% 28.2%
2672137 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.89 84.0 5.57e-01 98.3% 29.4%
144144 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.89 84.0 5.56e-01 98.3% 29.2%
4879141 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.88 83.0 5.53e-01 99.1% 29.8%
3110491 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.87 82.0 5.49e-01 98.3% 29.6%
2702071 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.84 79.0 5.30e-01 99.1% 29.7%
152631 5.1.3.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neur 0.82 75.0 5.12e-01 99.1% 30.8%
3675696 5.1.4.288 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › APEH_N 0.72 66.0 4.31e-01 99.1% 32.7%
3290396 5.1.2.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_32N 0.72 67.0 4.91e-01 100.0% 43.8%
3717566 5.1.3.28 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 0.71 66.0 4.99e-01 100.0% 62.0%
2336349 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.70 51.0 5.71e-01 89.7% 98.9%
5052460 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.69 57.0 4.01e-01 98.3% 28.8%
3709769 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.68 59.0 4.24e-01 99.1% 33.3%
4940718 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.68 62.0 4.34e-01 100.0% 46.0%
3104388 5.1.5.92 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, Beta-prop_EML 0.67 54.0 3.84e-01 98.3% 28.3%
3487711 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.67 54.0 3.94e-01 98.3% 31.4%
3285940 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.67 55.0 4.14e-01 97.4% 36.5%
3929846 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.66 54.0 3.99e-01 99.1% 33.8%
3498059 5.1.5.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WDR93 0.65 60.0 3.93e-01 98.3% 31.5%
3827202 5.1.11.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 9-bladed › eIF2A 0.65 53.0 4.28e-01 97.4% 45.9%
5010861 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.65 59.0 4.09e-01 99.1% 33.0%
3202006 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.65 51.0 3.57e-01 98.3% 25.3%
3359021 5.1.5.86 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Kelch_1 0.65 57.0 4.18e-01 99.1% 38.0%
3819893 5.1.4.288 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › APEH_N 0.65 58.0 3.93e-01 100.0% 48.6%
3352484 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.64 57.0 4.04e-01 99.1% 34.7%
5032832 5.1.5.11 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PQQ_2 0.64 56.0 3.82e-01 97.4% 26.7%
3484788 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.64 56.0 3.74e-01 96.6% 36.3%
3494110 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.64 58.0 3.78e-01 100.0% 31.9%
4083857 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.63 37.0 3.52e-01 90.6% 49.3%
3395398 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 56.0 3.84e-01 98.3% 30.7%
2320506 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 37.0 3.46e-01 89.7% 47.9%
3807987 5.1.3.6 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.62 55.0 4.01e-01 97.4% 35.6%
3761733 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.61 56.0 4.02e-01 100.0% 48.5%
3340517 5.1.3.6 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.61 54.0 4.00e-01 97.4% 43.0%
None — 0.61 55.0 3.79e-01 98.3% 36.9%
3877094 5.1.3.4 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › WD40 0.61 55.0 3.98e-01 100.0% 48.2%
3832491 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.61 54.0 3.94e-01 97.4% 38.4%
3508969 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.61 54.0 4.17e-01 98.3% 44.2%
3844416 5.1.4.229 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_EMC1_N 0.61 54.0 3.75e-01 99.1% 29.5%
4013508 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.61 53.0 3.84e-01 97.4% 35.6%
3169693 5.1.4.80 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Utp8_b_propeller 0.60 54.0 3.74e-01 97.4% 31.1%
3286197 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.60 54.0 4.02e-01 98.3% 61.0%
3716605 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.60 39.0 3.50e-01 85.5% 48.1%
3382673 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.60 51.0 3.75e-01 99.1% 35.4%
3351507 5.1.3.65 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF295 0.60 49.0 3.51e-01 88.0% 49.7%
3990496 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.60 36.0 4.39e-01 86.3% 98.6%
3179065 5.1.4.8 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CNH 0.60 54.0 3.71e-01 97.4% 38.7%
3582493 5.1.4.139 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_2 0.60 53.0 3.69e-01 98.3% 35.3%
2123569 5.1.4.6 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40 0.59 54.0 3.69e-01 98.3% 29.6%
3781730 5.1.11.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 9-bladed › Utp8_b_propeller 0.59 53.0 3.70e-01 97.4% 32.2%
5036897 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.59 35.0 3.24e-01 86.3% 46.9%
3492017 5.1.4.276 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, Beta-prop_WDR75_2nd 0.59 53.0 3.22e-01 98.3% 17.9%
5055395 5.1.4.40 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PQQ_2 0.58 52.0 3.68e-01 98.3% 31.9%
3218632 77.1.1.0 ↗ beta meanders › open-sided beta-meander › Outer surface protein › Outer surface protein 0.58 40.0 4.41e-01 94.0% 88.3%
3706360 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.58 52.0 3.78e-01 100.0% 40.0%
4033429 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.57 37.0 4.39e-01 86.3% 96.2%
4993189 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.55 29.0 3.95e-01 74.4% 100.0%
1170463 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.54 38.0 4.24e-01 85.5% 93.4%
3487462 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.53 37.0 3.56e-01 88.9% 64.6%
1760289 809.1.1.3 ↗ a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP › DUF3862 0.53 32.0 3.81e-01 74.4% 86.9%
5048797 64.1.1.0 ↗ beta meanders › WW domain-like › WW domain › WW domain 0.52 36.0 3.90e-01 96.6% 85.3%
3567966 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.51 36.0 3.99e-01 90.6% 89.5%
3690594 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.50 43.0 2.79e-01 94.0% 31.8%
D3 medium residues 226-318
PDB
Domain cluster: rep: neuraminidase__YP_308668__Influenza_A_virus_-A_goose_Guangdong_1_1996-H5N1--__93838__D223-295
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00064.26 best Neur 123.5 1.10e-35 100.0% 23.5%