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non-structural_protein_NS2b
Euk-VirYellow_fever_virus
non-structural_protein_NS2b__NP_776004__Yellow_fever_virus__11089
Identity
- Accession:
- NP_776004 ↗
- Protein ID:
- non-structural_protein_NS2b
- Kingdom:
- euk
Quality
70.1
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Yellow_fever_virus
TaxID: 11089
Cluster
View cluster (16 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-50_72-129
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01002.24 best | Flavi_NS2B | 86.4 | 2.10e-24 | 57.1% | 45.7% |
| PF01002.24 | Flavi_NS2B | 67.3 | 1.70e-18 | 46.7% | 37.0% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 57.0 | 4.44e-01 | 93.3% | 45.3% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 55.0 | 4.28e-01 | 92.4% | 45.1% |
| 1t6aA02 | 3.30.310.120 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein | 0.62 | 28.0 | 3.20e-01 | 74.3% | 56.4% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.60 | 42.0 | 3.43e-01 | 72.4% | 39.6% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 52.0 | 3.88e-01 | 97.1% | 49.8% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.55 | 35.0 | 3.49e-01 | 81.0% | 59.8% |
| 1e6vB02 | 1.20.840.10 | Mainly Alpha › Up-down Bundle › Methyl-coenzyme M Reductase; Chain B, domain 2 › Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal | 0.55 | 42.0 | 3.05e-01 | 81.0% | 32.2% |
| 3hwcA01 | 1.10.3140.10 | Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1 | 0.54 | 39.0 | 3.50e-01 | 74.3% | 66.7% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 47.0 | 3.94e-01 | 100.0% | 60.4% |
| 2q14B01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.53 | 46.0 | 3.69e-01 | 100.0% | 88.0% |
| 3d8lA00 | 1.10.8.940 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein, phage p2 ORF12 | 0.53 | 35.0 | 3.70e-01 | 77.1% | 76.9% |
| 1go4A00 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.53 | 40.0 | 3.26e-01 | 79.0% | 82.1% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.53 | 40.0 | 2.96e-01 | 81.0% | 89.6% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.51 | 39.0 | 3.76e-01 | 81.9% | 73.1% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3799917 | 633.23.1.17 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DuoxA | 0.62 | 51.0 | 3.80e-01 | 87.6% | 99.2% |
| 3242949 | 633.23.1.17 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DuoxA | 0.61 | 50.0 | 3.69e-01 | 87.6% | 97.0% |
| 3930773 | 633.23.1.17 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DuoxA | 0.61 | 49.0 | 3.65e-01 | 87.6% | 95.6% |
| 3938116 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 45.0 | 3.43e-01 | 81.0% | 41.6% |
| 3591919 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 51.0 | 3.47e-01 | 100.0% | 57.7% |
| 4943511 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.57 | 43.0 | 3.49e-01 | 80.0% | 65.4% |
| 3601219 | 3447.1.1.9 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24, DUF1295 | 0.57 | 42.0 | 3.44e-01 | 79.0% | 85.5% |
| 3530710 | 3447.1.1.7 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24, ICMT | 0.57 | 43.0 | 3.46e-01 | 80.0% | 85.0% |
| 3280676 | 150.8.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE | 0.56 | 39.0 | 3.33e-01 | 72.4% | 90.0% |
| 4956170 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.56 | 43.0 | 4.00e-01 | 83.8% | 73.2% |
| 3497809 | 3447.1.1.7 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24, ICMT | 0.55 | 42.0 | 3.33e-01 | 81.0% | 85.1% |
| 3632975 | 3447.1.1.1 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24 | 0.55 | 43.0 | 3.37e-01 | 84.8% | 86.0% |
| 5045206 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.54 | 40.0 | 2.61e-01 | 77.1% | 81.8% |
| 3245464 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 48.0 | 3.41e-01 | 99.0% | 48.9% |
| 3862966 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 47.0 | 3.35e-01 | 100.0% | 38.6% |
| 3530542 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 46.0 | 3.27e-01 | 94.3% | 33.6% |
| 4160558 | 3447.1.1.1 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24 | 0.53 | 41.0 | 3.34e-01 | 84.8% | 79.5% |
| 3969245 | 5051.1.1.9 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Transp_cyt_pur | 0.53 | 47.0 | 3.12e-01 | 100.0% | 93.8% |
| 3615606 | 3447.1.1.1 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24 | 0.53 | 41.0 | 3.39e-01 | 84.8% | 50.0% |
| 4015129 | 3447.1.1.0 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) | 0.53 | 41.0 | 3.31e-01 | 84.8% | 53.0% |
| 3987428 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.52 | 41.0 | 4.21e-01 | 84.8% | 94.0% |
| 3304324 | 101.1.2.106 ↗ | alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 | 0.51 | 28.0 | 2.66e-01 | 77.1% | 39.3% |
| 3560659 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 44.0 | 3.27e-01 | 100.0% | 51.0% |
| 3401124 | 3447.1.1.1 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24 | 0.51 | 38.0 | 3.19e-01 | 81.0% | 86.0% |
| 4943281 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.51 | 43.0 | 3.31e-01 | 95.2% | 74.0% |
| 3574069 | 604.12.1.62 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DuoxA | 0.50 | 40.0 | 3.78e-01 | 84.8% | 76.8% |