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non-structural_protein_NS3

Euk-Vir

Yellow_fever_virus

non-structural_protein_NS3__NP_776005__Yellow_fever_virus__11089

Identity

Accession:
NP_776005 ↗
Protein ID:
non-structural_protein_NS3
Kingdom:
euk

Quality

83.2 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Orthoflavivirus› Yellow_fever_virus

TaxID: 11089

Cluster

View cluster (28 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 23-169
PDB
Domain cluster: rep: 100_kDa_protein__YP_008130303__Citrus_vein_enation_virus__1301220__D379-571
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00949.28 best Peptidase_S7 144.4 2.60e-42 100.0% 94.7%
PF02907.22 Peptidase_S29 25.3 1.60e-05 95.2% 78.5%
D2 high residues 183-326
PDB
Domain cluster: rep: LD_Run2_08_scaffold_35_prodigal-single.1__X__X__00177__D121-323
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF00270.36 best DEAD 36.0 8.20e-09 100.0% 92.2%
PF04851.22 ResIII 28.0 2.70e-06 97.2% 84.2%
PF07652.21 Flavi_DEAD 227.0 1.30e-67 96.5% 93.2%
D3 high residues 337-432_453-478
PDB
Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00271.38 best Helicase_C 26.1 1.20e-05 77.0% 46.4%
D4 high residues 541-620
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20907.3 best Flav_NS3-hel_C 128.3 2.70e-37 100.0% 54.9%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mkkA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 40.0 2.58e-01 75.0% 45.4%
3weoA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 40.0 2.63e-01 76.2% 47.1%
5iaiA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 45.0 3.44e-01 96.2% 73.4%
6lcjD01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 37.0 2.61e-01 76.2% 38.0%
4ba0A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 38.0 2.49e-01 77.5% 33.3%
3ufbA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 35.0 2.38e-01 70.0% 39.1%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
286894 5101.1.1.1 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.98 95.0 7.45e-01 100.0% 54.4%
53546 5101.1.1.0 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase 0.98 93.0 7.51e-01 100.0% 58.1%
4878071 5101.1.1.1 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.95 91.0 7.19e-01 100.0% 54.8%
3922377 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.58 40.0 2.88e-01 71.2% 55.8%
3450110 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.57 40.0 2.63e-01 75.0% 38.9%
3912345 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.55 40.0 2.61e-01 75.0% 38.9%
5036421 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.54 44.0 2.89e-01 88.7% 59.1%
4011473 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.54 39.0 2.60e-01 76.2% 40.0%
3404705 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.54 39.0 2.60e-01 78.8% 51.0%
2774267 2002.1.1.87 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Melibiase 0.53 37.0 2.58e-01 76.2% 36.4%
1764102 1039.1.1.1 ↗ extended segments › Pre-mRNA-processing factor 31 C-terminal region › Pre-mRNA-processing factor 31 C-terminal region › Pre-mRNA-processing factor 31 C-terminal region › Prp31_C 0.51 31.0 2.81e-01 73.8% 42.1%
5082722 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.51 37.0 2.50e-01 77.5% 36.9%
2475320 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.50 43.0 2.60e-01 96.2% 54.0%
4990546 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.50 43.0 2.66e-01 97.5% 64.0%
5026030 2002.1.1.45 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd 0.50 40.0 2.68e-01 88.7% 62.0%
D5 medium residues 433-452_484-540
PDB
Domain cluster: rep: nonstructural_protein_NS3__YP_004734464_nonstructural_protein_NS3__Tembusu_virus__64293__D482-546
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20907.3 best Flav_NS3-hel_C 90.9 9.40e-26 83.1% 43.1%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2irmA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.52 40.0 2.73e-01 87.0% 83.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
286894 5101.1.1.1 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.94 69.0 5.35e-01 75.3% 39.5%
53546 5101.1.1.0 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase 0.89 61.0 4.90e-01 70.1% 39.7%
4878071 5101.1.1.1 ↗ alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.88 65.0 5.09e-01 76.6% 40.4%
3706948 109.1.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.53 41.0 3.10e-01 88.3% 95.3%