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non_structural_protein_NS2
Euk-VirHuman_bocavirus_4_NI
non_structural_protein_NS2__YP_002916059__Human_bocavirus_4_NI__1511883
Identity
- Accession:
- YP_002916059 ↗
- Protein ID:
- non_structural_protein_NS2
- Kingdom:
- euk
Quality
76.4
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Quintoviricetes›
Piccovirales›
Parvoviridae›
Bocaparvovirus›
Human_bocavirus_4_NI
TaxID: 1511883
Cluster
View cluster (44 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 15-264
Domain cluster:
rep: NS1__YP_009507375__Chipmunk_parvovirus__56820__D1-203
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF22419.3 best | HBoV_NS1-like_N | 313.7 | 1.20e-93 | 92.4% | 98.0% |
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.96 | 95.0 | 9.23e-01 | 100.0% | 94.0% |
| 6usmB01 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.74 | 44.0 | 5.67e-01 | 92.0% | 100.0% |
| 1m55A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.73 | 53.0 | 6.06e-01 | 100.0% | 96.4% |
| 2x3gA00 | 3.30.70.1910 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.71 | 31.0 | 4.50e-01 | 87.2% | 87.1% |
| 2lqjA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.70 | 26.0 | 4.26e-01 | 78.4% | 90.4% |
| 1zpvA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.70 | 25.0 | 4.29e-01 | 76.8% | 95.3% |
| 1f08B00 | 3.40.1310.10 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.67 | 32.0 | 4.13e-01 | 100.0% | 77.2% |
| 4clfA02 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.66 | 33.0 | 3.77e-01 | 98.8% | 62.0% |
| 1r9wA00 | 3.40.1310.10 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.66 | 31.0 | 4.18e-01 | 100.0% | 81.9% |
| 2kjwA00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.65 | 26.0 | 3.99e-01 | 75.2% | 90.6% |
| 3p96A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 24.0 | 4.08e-01 | 77.2% | 98.8% |
| 1xmbA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 27.0 | 4.19e-01 | 75.2% | 98.0% |
| 1pbuA00 | 3.30.70.1010 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Translation elongation factor EF1B, gamma chain, conserved domain | 0.62 | 31.0 | 3.79e-01 | 94.0% | 72.2% |
| 2l03A00 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.57 | 19.0 | 3.28e-01 | 93.6% | 91.9% |
| 3hh7A00 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.57 | 16.0 | 3.20e-01 | 93.2% | 92.3% |
| 1hbgA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 32.0 | 4.10e-01 | 71.6% | 97.3% |
| 2kcuA00 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.54 | 31.0 | 3.73e-01 | 97.6% | 82.5% |
| 3gk6A00 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.54 | 31.0 | 3.81e-01 | 97.6% | 88.2% |
| 2govA01 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.54 | 33.0 | 3.85e-01 | 97.6% | 84.4% |
| 2abyA00 | 3.30.70.1980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF09406, DUF2004 | 0.53 | 25.0 | 3.43e-01 | 90.4% | 86.9% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 30.0 | 3.86e-01 | 70.0% | 100.0% |
| 4ndhB00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.51 | 29.0 | 3.40e-01 | 100.0% | 77.5% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2834623 | 304.55.1.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N | 0.73 | 50.0 | 5.98e-01 | 99.6% | 99.4% |
| 4880004 | 304.55.1.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N | 0.72 | 53.0 | 5.85e-01 | 100.0% | 90.9% |
| 1491756 | 304.55.1.9 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PV_NSP1 | 0.69 | 61.0 | 6.14e-01 | 100.0% | 91.9% |
| 3874532 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.67 | 32.0 | 4.67e-01 | 75.2% | 98.3% |
| 3213802 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.67 | 32.0 | 4.35e-01 | 73.2% | 86.9% |
| 4350848 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.62 | 25.0 | 3.99e-01 | 94.8% | 95.8% |
| 3672532 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 29.0 | 4.24e-01 | 73.2% | 98.2% |
| 3802060 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.61 | 39.0 | 3.91e-01 | 100.0% | 61.2% |
| 4032691 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.61 | 24.0 | 3.84e-01 | 94.4% | 93.7% |
| 3677440 | 862.1.1.11 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R | 0.59 | 38.0 | 3.91e-01 | 100.0% | 64.1% |
| 4007464 | 304.55.1.19 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Inovirus_Gp2 | 0.59 | 40.0 | 4.55e-01 | 94.4% | 90.5% |
| 4025874 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.58 | 25.0 | 3.70e-01 | 76.8% | 91.4% |
| 3512046 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.58 | 38.0 | 3.86e-01 | 100.0% | 63.9% |
| 4139791 | 304.41.1.1 ↗ | a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N | 0.57 | 35.0 | 4.25e-01 | 100.0% | 93.1% |
| 4511949 | 304.48.1.74 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Phage_GPA | 0.56 | 39.0 | 4.06e-01 | 95.2% | 73.3% |
| 3342333 | 304.28.1.10 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Helitron_like_N | 0.56 | 31.0 | 3.58e-01 | 100.0% | 71.9% |
| 4673704 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.56 | 36.0 | 3.48e-01 | 100.0% | 55.0% |
D2
high
residues 310-365
Domain cluster:
rep: non-structural_protein_1__YP_009272913__Mink_bocavirus_1__2259808__D352-409
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 24.3 | 2.00e-05 | 100.0% | 19.9% |
D3
medium
residues 367-410_540-616
Domain cluster:
rep: NS1_protein__YP_009229908__Bat_bocavirus__1329649__D376-421_558-623
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 26.3 | 4.90e-06 | 38.8% | 17.0% |
D4
medium
residues 411-539
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 206.0 | 7.90e-61 | 100.0% | 47.6% |
| PF00519.24 | PPV_E1_C | 31.2 | 1.90e-07 | 91.5% | 36.3% |