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non_structural_protein_P4
Euk-VirSleeping_disease_virus
non_structural_protein_P4__NP_740656__Sleeping_disease_virus__78540
Identity
- Accession:
- NP_740656 ↗
- Protein ID:
- non_structural_protein_P4
- Kingdom:
- euk
Quality
76.9
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Togaviridae›
Alphavirus›
Sleeping_disease_virus
TaxID: 78540
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 34-102
D2
high
residues 510-606
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 43.0 | 4.58e-01 | 84.5% | 80.0% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.58 | 45.0 | 3.71e-01 | 82.5% | 58.3% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 46.0 | 4.27e-01 | 91.8% | 66.7% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 43.0 | 3.78e-01 | 81.4% | 67.5% |
| 2xevB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 33.0 | 3.10e-01 | 80.4% | 43.5% |
| 4xeaA01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.54 | 42.0 | 3.16e-01 | 82.5% | 78.4% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 47.0 | 4.60e-01 | 100.0% | 98.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 41.0 | 3.79e-01 | 82.5% | 67.2% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 40.0 | 2.88e-01 | 83.5% | 74.0% |
| 2c0gA02 | 1.20.1150.12 | Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain | 0.52 | 40.0 | 3.90e-01 | 82.5% | 92.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 45.0 | 4.38e-01 | 99.0% | 89.6% |
| 5fb0A02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 38.0 | 3.67e-01 | 78.4% | 84.8% |
| 4ga4A01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.51 | 30.0 | 3.44e-01 | 84.5% | 83.6% |
| 2lt3A01 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.51 | 32.0 | 3.19e-01 | 79.4% | 59.0% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.50 | 44.0 | 3.96e-01 | 99.0% | 87.9% |
| 7ccmB01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.50 | 38.0 | 3.42e-01 | 82.5% | 61.5% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3935030 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 45.0 | 4.41e-01 | 78.4% | 85.7% |
| 3867529 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 35.0 | 3.14e-01 | 80.4% | 40.0% |
| 5022752 | 7512.1.1.48 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF3492 | 0.58 | 45.0 | 3.38e-01 | 84.5% | 67.1% |
| 5052139 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.58 | 49.0 | 4.40e-01 | 92.8% | 85.5% |
| 3495156 | 109.58.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA repair protein Rev1 C-terminal domain › DNA repair protein Rev1 C-terminal domain › REV1_C | 0.58 | 40.0 | 4.22e-01 | 85.6% | 81.2% |
| 3627759 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.58 | 37.0 | 2.45e-01 | 75.3% | 15.1% |
| 3996179 | 109.4.1.1353 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11, TPR_16 | 0.57 | 32.0 | 2.78e-01 | 79.4% | 32.5% |
| 3888823 | 109.4.1.2600 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_11 | 0.56 | 34.0 | 2.86e-01 | 87.6% | 36.3% |
| 4217721 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 33.0 | 3.15e-01 | 86.6% | 50.4% |
| 4999599 | 109.4.1.5 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 | 0.54 | 31.0 | 2.65e-01 | 79.4% | 30.6% |
| 3172977 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.53 | 39.0 | 3.56e-01 | 94.8% | 58.5% |
| 3589720 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 36.0 | 3.13e-01 | 71.1% | 55.2% |
| 3345939 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.52 | 41.0 | 3.81e-01 | 84.5% | 85.0% |
| 3560546 | 109.4.1.319 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_2 | 0.50 | 34.0 | 2.70e-01 | 90.7% | 31.9% |
| 4940332 | 109.4.1.195 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_11 | 0.50 | 33.0 | 2.99e-01 | 91.8% | 47.4% |
D3
medium
residues 217-247_320-341_377-411_425-453
Domain cluster:
rep: ORF_1b__YP_003289291__Strawberry_pallidosis-associated_virus__227507__D117-174_213-235_276-309
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00978.27 best | RdRP_2 | 35.4 | 8.50e-09 | 56.4% | 17.3% |
D4
medium
residues 342-376_454-509
Domain cluster:
rep: hypothetical_protein_2__YP_009345057__Xinzhou_nematode_virus_7__1923775__D238-258_337-401
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00978.27 best | RdRP_2 | 47.2 | 2.20e-12 | 61.5% | 11.4% |