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nonstructural_polyprotein

Euk-Vir

Solenopsis_invicta_virus_1

nonstructural_polyprotein__YP_164440__Solenopsis_invicta_virus_1__294369

Identity

Accession:
YP_164440 ↗
Protein ID:
nonstructural_polyprotein
Kingdom:
euk

Quality

71.4 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Picornavirales› Dicistroviridae› Aparavirus› Solenopsis_invicta_virus_1

TaxID: 294369

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 22-255
PDB
Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00910.29 best RNA_helicase 107.7 6.00e-31 49.6% 100.0%
D2 high residues 1316-1387
PDB
Domain cluster: representative
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.73 57.0 4.39e-01 83.3% 65.6%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 57.0 4.28e-01 84.7% 80.2%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 55.0 4.56e-01 84.7% 65.4%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.70 62.0 4.70e-01 100.0% 72.3%
3cf6E03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.69 58.0 4.87e-01 95.8% 71.8%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 54.0 5.33e-01 84.7% 93.3%
4i9cA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 54.0 3.87e-01 87.5% 29.9%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 52.0 4.27e-01 84.7% 94.2%
3vwaA03 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.66 55.0 3.71e-01 97.2% 27.5%
1zzpA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 51.0 4.45e-01 84.7% 66.1%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 51.0 5.11e-01 84.7% 94.7%
5m9dA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 55.0 4.55e-01 100.0% 63.0%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 49.0 3.49e-01 83.3% 44.7%
6vptA01 1.50.10.160 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.64 56.0 4.03e-01 98.6% 61.7%
2aj4B03 1.20.1440.340 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 50.0 3.90e-01 86.1% 78.4%
1ls1A01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.64 47.0 4.46e-01 80.6% 66.3%
4jxtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 54.0 4.53e-01 97.2% 63.8%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.63 52.0 4.76e-01 93.1% 84.5%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 48.0 4.54e-01 83.3% 83.9%
5lnkJ01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.62 48.0 3.71e-01 84.7% 40.2%
3s63A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.61 43.0 4.03e-01 75.0% 59.1%
1ks8A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.60 49.0 3.16e-01 97.2% 36.5%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 46.0 3.71e-01 84.7% 74.3%
1dosA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.60 51.0 3.33e-01 97.2% 27.4%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.60 44.0 4.29e-01 81.9% 77.6%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 47.0 3.94e-01 95.8% 77.0%
7xuxB01 1.10.3290.10 Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain 0.59 50.0 3.58e-01 100.0% 37.6%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 52.0 4.69e-01 100.0% 90.2%
4jkzA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 49.0 3.80e-01 100.0% 78.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 45.0 4.44e-01 86.1% 82.1%
2lvfA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.56 46.0 4.08e-01 95.8% 78.1%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 46.0 3.63e-01 98.6% 82.7%
8gtzA03 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.54 46.0 3.55e-01 100.0% 61.3%
1kpsB00 1.25.40.200 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain 0.54 44.0 3.61e-01 97.2% 58.3%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.54 37.0 3.67e-01 73.6% 73.1%
1t98A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.76e-01 80.6% 77.0%
1ysyA00 1.10.8.370 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › nsp7 replicase 0.52 39.0 3.79e-01 84.7% 78.8%
2id3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 42.0 3.58e-01 98.6% 81.0%
7w6bA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.51 41.0 2.90e-01 94.4% 60.6%
8befJ01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.51 40.0 3.07e-01 88.9% 36.5%
2c12A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 42.0 3.60e-01 97.2% 78.0%
5noeA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.51 41.0 3.79e-01 93.1% 77.3%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3092371 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.83 79.0 6.86e-01 100.0% 70.6%
3230224 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.73 63.0 4.81e-01 95.8% 86.9%
3223294 109.4.1.140 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NatB_MDM20 0.72 65.0 4.93e-01 100.0% 80.0%
4169956 604.12.1.26 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › HemX 0.72 56.0 5.60e-01 84.7% 86.7%
3838379 601.53.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Flagellin glycosyltransferase Maf helical bundle domain › Flagellin glycosyltransferase Maf helical bundle domain 0.72 54.0 4.73e-01 81.9% 55.5%
3681479 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 54.0 4.54e-01 83.3% 63.3%
3714093 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 57.0 5.20e-01 93.1% 84.0%
3992327 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 59.0 4.26e-01 100.0% 52.1%
None — 0.67 58.0 3.88e-01 100.0% 29.5%
3393335 109.4.1.265 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CEP104-like_TOG 0.67 58.0 3.94e-01 100.0% 34.7%
3382589 633.16.1.0 ↗ alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.66 51.0 4.23e-01 84.7% 48.9%
3460317 109.4.1.1323 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IMB1 0.66 57.0 3.67e-01 100.0% 25.1%
3274434 198.1.1.2 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 0.64 45.0 4.28e-01 75.0% 61.2%
3679122 109.4.1.1744 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_EZ, TPR_IMB1 0.64 54.0 3.72e-01 100.0% 35.4%
3957983 2002.1.1.4 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Alpha-amylase 0.64 56.0 3.23e-01 97.2% 55.9%
3462735 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 54.0 4.15e-01 95.8% 75.3%
3571190 109.25.1.7 ↗ alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › PF26588 0.63 54.0 4.71e-01 98.6% 68.7%
3640309 109.4.1.169 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rad26-like_helical_rpts,Rad26-like_C,Rad26-like_N 0.63 53.0 3.21e-01 100.0% 15.1%
3694485 601.7.1.37 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Las1 0.63 48.0 3.69e-01 83.3% 65.5%
3939289 170.1.1.0 ↗ alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C 0.62 45.0 4.07e-01 77.8% 62.0%
3263245 198.1.1.1 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 0.62 43.0 4.29e-01 77.8% 69.2%
3753325 109.27.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › BACK 0.62 53.0 4.56e-01 100.0% 60.0%
3967002 3843.1.1.27 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › COX4_pro 0.61 47.0 4.47e-01 83.3% 87.1%
4400461 6028.1.1.0 ↗ alpha bundles › Ribosome modulation factor › Ribosome modulation factor › Ribosome modulation factor 0.60 48.0 4.85e-01 95.8% 92.9%
3546135 10.12.1.108 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › POPDC1-3 0.59 47.0 4.68e-01 88.9% 86.7%
3879538 604.12.1.74 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › POPDC1-3 0.59 47.0 4.67e-01 88.9% 86.7%
1503553 3796.1.1.1 ↗ alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Isd_H_B_linker 0.58 45.0 4.44e-01 86.1% 82.1%
3935918 109.4.1.645 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BLM10_mid 0.57 48.0 3.51e-01 100.0% 73.8%
5061893 4070.1.1.3 ↗ alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › DUF3267 0.55 46.0 3.32e-01 95.8% 77.3%
4567807 397.7.1.6 ↗ few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › PF29718 0.53 38.0 3.93e-01 76.4% 92.3%
D3 medium residues 622-633_730-835
PDB
Domain cluster: rep: putative_3C_peptidase__YP_009553718__tremovirus_B1__2058161__D98-201
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF12381.14 best Peptidase_C3G 27.0 4.30e-06 97.5% 48.0%
PF00548.27 Peptidase_C3 27.4 4.10e-06 47.5% 22.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1havB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.86 72.0 7.69e-01 92.4% 99.0%
2hrvA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.83 60.0 6.65e-01 93.2% 91.6%
4fvdA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.82 59.0 6.55e-01 93.2% 92.6%
2as9B01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.81 51.0 5.56e-01 91.5% 75.2%
2bhgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.79 57.0 6.12e-01 93.2% 86.3%
4ic5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 57.0 6.04e-01 93.2% 84.6%
1ywuA00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.68 44.0 4.38e-01 82.2% 62.4%
2vpaA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 55.0 4.55e-01 89.8% 72.5%
3dnhA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 53.0 4.88e-01 89.0% 90.1%
3nziA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.64 42.0 4.47e-01 83.9% 75.5%
4rqyA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.63 41.0 4.09e-01 82.2% 62.6%
1ci0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 51.0 4.23e-01 89.0% 78.9%
2qsdA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.60 35.0 4.32e-01 71.2% 98.5%
2z4dA00 2.30.29.70 Mainly Beta › Roll › PH-domain like › Proteasomal ubiquitin receptor Rpn13/ADRM1 0.58 31.0 3.46e-01 81.4% 64.6%
6brbD00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 33.0 3.75e-01 78.0% 77.0%
1cv8A00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 42.0 3.74e-01 80.5% 60.7%
3j7aV00 2.40.50.1000 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 32.0 3.00e-01 89.8% 47.9%
6toaE01 2.40.10.270 Mainly Beta › Beta Barrel › Thrombin, subunit H › Bacteriophage SPP1 head-tail adaptor protein 0.50 36.0 3.97e-01 75.4% 100.0%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
261 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.84 78.0 6.23e-01 97.5% 96.2%
4960051 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.78 58.0 5.00e-01 89.8% 52.3%
3950458 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.77 57.0 4.82e-01 94.1% 50.0%
3280955 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.72 67.0 5.33e-01 100.0% 88.4%
3950281 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.69 64.0 5.08e-01 100.0% 85.3%
3276425 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.68 63.0 4.64e-01 100.0% 84.4%
3724875 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.66 60.0 4.45e-01 100.0% 84.7%
3180837 1.1.5.30 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_oxase_2 0.66 55.0 4.25e-01 89.0% 82.4%
3783835 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.63 58.0 4.42e-01 100.0% 83.0%
4500974 1.1.5.25 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.62 44.0 4.42e-01 83.9% 71.7%
2095485 1.1.5.38 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_C107 0.62 58.0 4.70e-01 100.0% 89.9%
3434219 4.25.1.2 ↗ beta barrels › SH3 › Auxin response factor dimerization domain and ancillary domain › Auxin response factor dimerization domain and ancillary domain › BRWD_AD 0.62 37.0 4.05e-01 89.8% 72.6%
4217523 1.1.5.25 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.59 45.0 4.46e-01 81.4% 79.2%
4940074 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 37.0 4.11e-01 73.7% 78.9%
3868052 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.57 44.0 4.13e-01 81.4% 99.3%
3180573 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.57 38.0 4.20e-01 100.0% 84.2%
3237933 269.1.1.1 ↗ a+b complex topology › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen_C 0.55 42.0 3.28e-01 79.7% 80.4%
3940556 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 36.0 3.70e-01 76.3% 69.1%
5051927 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.53 39.0 3.89e-01 75.4% 100.0%
4930955 7099.1.1.1 ↗ a+b complex topology › VP5 N-terminal domain › VP5 N-terminal domain › VP5 N-terminal domain › Viral_env_HRPV 0.53 43.0 3.21e-01 89.0% 62.2%
3390499 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.53 39.0 3.75e-01 78.8% 91.4%
3221297 269.1.1.1 ↗ a+b complex topology › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen_C 0.52 39.0 3.09e-01 80.5% 83.5%
3177250 75.1.1.1 ↗ beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase 0.52 38.0 3.09e-01 76.3% 96.9%
3587296 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 38.0 3.72e-01 78.8% 93.1%
4024974 219.1.1.14 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Josephin 0.50 38.0 3.25e-01 100.0% 48.7%
D4 medium residues 634-729_836-870
PDB
Domain cluster: rep: 3C__YP_009111405__torchivirus_A1__1578826__D3-94
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qa7A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.82 62.0 6.81e-01 80.9% 93.6%
2bhgA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.80 53.0 6.32e-01 70.2% 95.7%
2z9iC01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.72 46.0 5.41e-01 70.2% 91.3%
5eokA05 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.72 57.0 4.71e-01 84.0% 97.8%
1shyA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 54.0 6.01e-01 81.7% 100.0%
2o8lA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 50.0 5.59e-01 71.0% 98.0%
5f8zA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 55.0 5.95e-01 80.9% 100.0%
5lpeB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 49.0 5.73e-01 80.2% 100.0%
1p57B02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 55.0 5.84e-01 81.7% 94.1%
1dx5M02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 54.0 5.70e-01 80.9% 100.0%
2oq5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 53.0 5.92e-01 84.0% 100.0%
2as9A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 47.0 5.55e-01 71.0% 97.9%
3dfjA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 55.0 5.92e-01 84.7% 100.0%
2b9lA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 57.0 5.38e-01 88.5% 80.3%
5dj7A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 53.0 5.74e-01 82.4% 97.2%
1eq9A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 53.0 5.82e-01 80.9% 100.0%
1a5iA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 53.0 5.62e-01 81.7% 100.0%
6r2wH02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 54.0 5.88e-01 83.2% 100.0%
1m9uA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 51.0 5.55e-01 77.9% 100.0%
1ym0A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 54.0 5.75e-01 83.2% 100.0%
2f91A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 52.0 5.61e-01 80.9% 100.0%
5lhrA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.67 52.0 5.54e-01 81.7% 100.0%
1ao5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.67 51.0 5.46e-01 80.2% 100.0%
1ltoA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.67 53.0 5.73e-01 84.0% 100.0%
3tvjB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 51.0 5.60e-01 80.2% 100.0%
2olgA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 52.0 5.32e-01 82.4% 100.0%
7pzoA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 47.0 5.42e-01 75.6% 100.0%
3h7oA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 52.0 5.54e-01 82.4% 100.0%
1fiwA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 53.0 5.54e-01 84.7% 100.0%
1ekbB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 52.0 5.69e-01 83.2% 100.0%
3h7tA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.65 50.0 5.39e-01 81.7% 95.5%
1dleA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.63 52.0 5.29e-01 87.8% 98.4%
5c94A00 2.40.10.250 Mainly Beta › Beta Barrel › Thrombin, subunit H › Replicase NSP9 0.54 40.0 4.25e-01 81.7% 87.9%
6az1E03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.53 24.0 3.08e-01 86.3% 72.2%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
261 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.85 66.0 5.45e-01 80.2% 96.7%
376155 1.1.17.2 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_C3 0.79 64.0 5.45e-01 84.0% 97.4%
3232599 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 60.0 4.70e-01 84.7% 98.1%
3017386 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.73 60.0 4.76e-01 85.5% 96.4%
3544606 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 60.0 4.58e-01 85.5% 92.9%
3498508 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 57.0 4.66e-01 82.4% 94.6%
3403314 1.1.5.46 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF1986 0.73 59.0 4.94e-01 84.7% 93.0%
3534236 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 58.0 4.48e-01 84.0% 95.4%
3409555 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 62.0 4.88e-01 91.6% 97.4%
3525486 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 58.0 4.72e-01 83.2% 98.7%
3409584 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 59.0 4.57e-01 85.5% 94.1%
3555476 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 60.0 4.73e-01 86.3% 89.2%
3527303 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 59.0 4.61e-01 85.5% 96.6%
3390983 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 57.0 4.56e-01 83.2% 90.6%
3397483 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 59.0 4.53e-01 85.5% 94.3%
4641660 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.60e-01 84.7% 95.4%
3406384 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.70e-01 86.3% 96.4%
4189226 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 57.0 4.70e-01 83.2% 95.2%
3565221 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.56e-01 84.0% 96.9%
3798415 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.72 59.0 4.63e-01 86.3% 97.4%
3798540 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.62e-01 86.3% 95.2%
3405366 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.60e-01 85.5% 98.5%
3393791 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.61e-01 84.0% 86.0%
4881914 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.72 56.0 4.77e-01 80.2% 98.5%
3411242 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 61.0 4.79e-01 89.3% 98.1%
3513910 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.59e-01 85.5% 95.4%
3398931 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.71e-01 87.0% 98.4%
3513169 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.55e-01 86.3% 97.5%
3398006 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 59.0 4.76e-01 86.3% 93.7%
4056616 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.58e-01 84.0% 87.6%
3406163 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.65e-01 84.7% 92.7%
4519994 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 58.0 4.56e-01 85.5% 96.2%
3402403 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 61.0 4.71e-01 90.8% 95.7%
None — 0.72 60.0 4.75e-01 88.5% 98.4%
239 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 56.0 4.55e-01 82.4% 96.3%
3409540 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 56.0 4.52e-01 82.4% 98.4%
3859610 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 59.0 4.86e-01 87.0% 96.4%
3399484 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 57.0 4.67e-01 84.0% 94.3%
3929918 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 61.0 4.74e-01 90.8% 98.5%
157313 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 58.0 4.68e-01 85.5% 96.2%
3913731 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 60.0 4.63e-01 89.3% 92.7%
3719164 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.71 57.0 4.97e-01 84.0% 93.7%
3555390 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 58.0 4.65e-01 85.5% 91.0%
3397582 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 58.0 4.63e-01 85.5% 94.7%
3397710 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 58.0 4.66e-01 86.3% 95.9%
3395929 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 56.0 4.68e-01 84.0% 96.4%
4672350 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 55.0 4.44e-01 81.7% 90.6%
3611892 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.71 56.0 4.88e-01 82.4% 93.7%
3902537 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 57.0 4.54e-01 84.0% 90.2%
3402456 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 57.0 4.94e-01 84.7% 95.4%
3412772 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 57.0 4.60e-01 84.7% 91.6%
3389000 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.70 57.0 4.62e-01 85.5% 90.0%
3410554 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.70 59.0 4.80e-01 89.3% 96.7%
4545500 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.70 57.0 4.64e-01 85.5% 94.4%
3599795 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.70 59.0 4.54e-01 89.3% 87.9%
4770105 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.70 51.0 4.95e-01 75.6% 78.1%
3399384 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.70 57.0 4.53e-01 86.3% 98.0%
3601993 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.69 55.0 4.77e-01 83.2% 91.3%
3284072 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.69 54.0 4.41e-01 83.2% 87.4%
3401816 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.69 56.0 4.55e-01 87.0% 93.5%
2411954 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.69 50.0 4.26e-01 75.6% 49.3%
134808 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.68 54.0 4.43e-01 84.0% 94.0%
3633439 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.68 55.0 4.35e-01 87.0% 84.1%
3469125 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.57 47.0 4.81e-01 100.0% 90.8%
3997886 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.56 49.0 4.10e-01 94.7% 88.8%
4251395 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.55 51.0 4.61e-01 100.0% 90.8%
3464949 11.2.1.37 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF6598 0.54 34.0 3.67e-01 82.4% 75.5%
4621240 1.1.1.1 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp 0.52 45.0 3.40e-01 97.7% 96.5%
3244907 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 28.0 3.26e-01 78.6% 73.3%
3788990 1.1.1.27 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp, TAXi_N 0.51 44.0 3.24e-01 94.7% 40.2%
D5 medium residues 929-942_977-1090
PDB
Domain cluster: rep: NIa__YP_003620390__Freesia_mosaic_virus__421012__D109-224
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 55.8 4.70e-15 100.0% 26.9%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2541763 304.48.1.8 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.79 76.0 5.20e-01 100.0% 38.9%
1173784 304.48.1.8 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.76 72.0 5.00e-01 100.0% 38.8%
None — 0.76 72.0 5.01e-01 100.0% 39.1%
4871000 304.48.1.8 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.74 71.0 5.39e-01 100.0% 54.0%
1875037 304.48.1.8 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.73 69.0 4.78e-01 100.0% 37.7%
1279063 304.48.1.13 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 0.73 68.0 4.60e-01 100.0% 33.2%
3250871 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 50.0 4.74e-01 89.1% 72.0%
D6 medium residues 943-976_1091-1115_1140-1183
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.58 26.0 3.49e-01 100.0% 82.4%
1x3kA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 36.0 3.23e-01 71.8% 90.5%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4636429 192.11.1.2 ↗ alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › CysS_C 0.53 29.0 3.75e-01 86.4% 98.2%
D7 medium residues 1116-1139_1184-1315
PDB
Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 52.9 3.60e-14 83.3% 22.2%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ckwA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.91 59.0 6.82e-01 88.5% 87.9%
6qwtA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.90 68.0 7.15e-01 100.0% 85.1%
1khvA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.90 64.0 7.04e-01 91.7% 87.7%
1ra6A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.89 55.0 6.75e-01 86.5% 92.5%
5jxsA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.89 67.0 7.03e-01 100.0% 84.5%
3h5xA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.88 58.0 6.70e-01 88.5% 88.8%
1s48A04 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.79 49.0 5.71e-01 92.9% 86.5%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 52.0 5.39e-01 100.0% 77.1%
1bqnA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 42.0 5.27e-01 88.5% 93.6%
7pliA03 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.72 36.0 5.04e-01 81.4% 100.0%
4ol8A01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.70 46.0 4.87e-01 100.0% 74.8%
1in0A01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 34.0 4.74e-01 80.8% 100.0%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.65 38.0 4.69e-01 84.0% 92.8%
1dcoA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.65 32.0 4.00e-01 71.8% 74.7%
7ykvB02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.65 31.0 3.70e-01 71.8% 67.3%
1hi8A03 3.30.70.1600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 54.0 5.18e-01 100.0% 79.5%
2ebbA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.63 33.0 4.03e-01 73.1% 79.2%
1usmA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.63 31.0 4.12e-01 70.5% 92.2%
4mt1A06 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.58 37.0 4.49e-01 77.6% 100.0%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 36.0 4.24e-01 94.9% 95.1%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 46.0 4.46e-01 89.7% 79.2%
1xviA02 3.30.980.20 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Putative mannosyl-3-phosphoglycerate phosphatase; domain 2 0.53 30.0 3.82e-01 78.8% 92.6%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.53 31.0 3.74e-01 78.2% 91.5%
4q5eA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 25.0 3.47e-01 90.4% 92.0%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.52 39.0 4.14e-01 81.4% 89.5%
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.52 46.0 4.19e-01 100.0% 72.2%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.51 44.0 3.88e-01 94.9% 92.1%
2amyA02 3.30.1240.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › Eukaryotic phosphomannomutase, cap domain 0.50 31.0 3.68e-01 73.1% 92.2%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.50 45.0 3.41e-01 99.4% 90.0%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2994348 304.48.1.9 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1,CoV_RPol_N 0.81 77.0 4.63e-01 100.0% 24.5%
5035783 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.73 39.0 5.20e-01 82.7% 100.0%
5366 304.48.1.15 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 0.73 60.0 4.35e-01 86.5% 40.5%
5027879 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.72 37.0 5.05e-01 71.2% 100.0%
3651505 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.71 36.0 4.80e-01 82.1% 92.5%
4882532 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 60.0 4.58e-01 93.6% 54.0%
3930235 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.66 53.0 4.43e-01 100.0% 50.2%
3935796 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.65 52.0 5.10e-01 100.0% 77.6%
4506359 101.1.2.751 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF6293_C 0.65 24.0 3.16e-01 71.2% 58.8%
3927736 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.64 52.0 4.49e-01 100.0% 55.4%
4163010 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.64 33.0 4.10e-01 71.8% 80.0%
4621064 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.64 32.0 4.07e-01 73.7% 81.1%
3571315 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.63 55.0 4.76e-01 100.0% 61.3%
3592685 305.2.1.0 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) 0.63 33.0 3.92e-01 73.7% 74.3%
3785854 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.62 33.0 3.90e-01 73.7% 72.5%
3983816 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 54.0 4.59e-01 92.9% 65.2%
3945039 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 57.0 4.45e-01 100.0% 57.3%
3927049 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.61 53.0 3.94e-01 94.2% 46.8%
4588604 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 49.0 4.09e-01 88.5% 48.9%
5018583 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.61 51.0 4.02e-01 88.5% 49.5%
4434853 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 51.0 4.36e-01 92.3% 58.3%
4041870 5104.1.1.0 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.59 27.0 3.06e-01 71.2% 52.5%
3390067 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.59 30.0 3.87e-01 70.5% 87.1%
5074512 3715.1.1.0 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e 0.59 33.0 3.98e-01 84.0% 84.0%
5049019 304.26.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP 0.58 37.0 4.43e-01 92.9% 97.1%
3968281 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 51.0 4.42e-01 94.2% 64.7%
3709829 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.58 31.0 3.62e-01 73.7% 73.3%
5027716 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.58 29.0 3.94e-01 70.5% 97.3%
4668511 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.57 29.0 3.78e-01 71.2% 87.1%
4826122 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.57 45.0 4.89e-01 85.9% 100.0%
4890630 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.57 52.0 4.53e-01 100.0% 65.7%
4497954 304.48.1.73 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N 0.57 49.0 3.95e-01 93.6% 50.3%
4536162 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.57 28.0 3.83e-01 70.5% 96.0%
3283852 304.48.1.10 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.56 42.0 4.71e-01 84.6% 97.6%
3249558 3012.1.1.1 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Trehalose_PPase 0.56 29.0 3.85e-01 79.5% 95.0%
3216767 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 51.0 4.19e-01 100.0% 58.2%
4033553 304.26.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP 0.55 36.0 4.17e-01 93.6% 97.1%
3782093 3012.1.1.1 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Trehalose_PPase 0.54 30.0 3.83e-01 72.4% 96.5%
5055130 5104.1.1.0 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.54 32.0 3.57e-01 74.4% 72.8%
3440366 101.1.2.106 ↗ alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 0.50 24.0 3.14e-01 83.3% 81.2%