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nonstructural_protein_1

Euk-Vir

Megabat_bufavirus_1

nonstructural_protein_1__YP_009241376__Megabat_bufavirus_1__1756191

Identity

Accession:
YP_009241376 ↗
Protein ID:
nonstructural_protein_1
Kingdom:
euk

Quality

83.3 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Protoparvovirus› Megabat_bufavirus_1

TaxID: 1756191

Cluster

View cluster (29 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 379-562
PDB
Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 208.1 1.80e-61 97.8% 63.5%
PF00519.24 PPV_E1_C 44.4 1.70e-11 66.8% 38.4%
PF19263.6 DUF5906 39.3 1.30e-09 57.1% 91.1%
D2 medium residues 1-32_193-269
PDB
Domain cluster: rep: NS1__YP_009508804__Cutavirus__1867125__D1-26_194-263
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF12433.15 best PV_NSP1 51.9 1.10e-13 67.9% 82.9%
D3 medium residues 33-192
PDB
Domain cluster: rep: NS1__YP_009552695__Rhinolophus_pusillus_bocaparvovirus_1__2053079__D4-183
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gs5A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.71 34.0 4.16e-01 91.3% 69.5%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 35.0 4.61e-01 99.4% 92.0%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.65 36.0 4.32e-01 100.0% 79.6%
1pu1A00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.64 37.0 4.71e-01 84.4% 100.0%
4i6yA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.64 39.0 4.53e-01 100.0% 87.3%
6j09A02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.62 25.0 3.45e-01 71.9% 73.1%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.62 58.0 4.81e-01 100.0% 61.3%
1vwxS02 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 23.0 3.17e-01 100.0% 68.4%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 32.0 3.87e-01 100.0% 82.2%
2onfA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.58 41.0 4.51e-01 86.9% 87.3%
2pn2A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.58 40.0 4.33e-01 86.9% 82.5%
3ramA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 34.0 3.94e-01 91.3% 82.2%
2ychA02 3.30.1490.300 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.55 18.0 2.85e-01 92.5% 73.3%
3tixA02 6.10.140.1690 Special › Helix non-globular › Helix Hairpins › 0.55 27.0 3.68e-01 71.2% 92.4%
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.53 30.0 3.89e-01 96.2% 98.9%
1uyvB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.52 37.0 3.06e-01 73.1% 97.3%
2vsqA06 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.51 31.0 3.83e-01 90.0% 95.2%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1491756 304.55.1.9 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PV_NSP1 0.92 84.0 7.04e-01 100.0% 60.9%
4945650 878.1.1.0 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 0.67 41.0 4.95e-01 85.6% 95.0%
4934927 304.19.1.0 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain 0.67 32.0 4.31e-01 90.6% 85.9%
5073850 304.43.1.6 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 › FLAD1_M 0.67 30.0 4.24e-01 80.6% 89.3%
3351840 284.1.3.2 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › OSR1_C 0.66 26.0 3.93e-01 100.0% 85.5%
4233442 304.4.1.54 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless 0.65 34.0 3.84e-01 91.3% 65.0%
4984314 304.43.1.6 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 › FLAD1_M 0.64 34.0 4.35e-01 100.0% 88.9%
5053097 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 32.0 3.99e-01 100.0% 78.9%
3368695 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 38.0 2.80e-01 100.0% 24.6%
4929428 304.162.1.0 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.61 31.0 4.04e-01 90.6% 89.4%
4315272 3281.1.1.3 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N,Proton_antipo_C 0.60 43.0 2.82e-01 73.1% 62.0%
4272772 3281.1.1.3 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N,Proton_antipo_C 0.60 43.0 2.82e-01 73.1% 59.7%
3902600 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.60 31.0 3.78e-01 90.6% 77.0%
None — 0.59 33.0 2.22e-01 100.0% 13.5%
5075397 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.59 40.0 4.49e-01 74.4% 88.8%
4047429 3281.1.1.3 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N,Proton_antipo_C 0.58 42.0 2.77e-01 73.1% 56.5%
5056801 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.58 40.0 4.44e-01 73.8% 88.8%
4025874 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 30.0 3.61e-01 100.0% 78.1%
4964003 241.1.1.29 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF5813 0.54 40.0 4.07e-01 95.0% 78.7%
4594258 3281.1.1.2 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N 0.51 37.0 2.57e-01 76.9% 76.1%
3646070 3636.1.1.0 ↗ a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.50 25.0 3.06e-01 85.0% 72.4%
4041628 3281.1.1.2 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N 0.50 38.0 2.69e-01 78.8% 75.1%
3924998 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.50 35.0 2.67e-01 70.0% 42.3%
3372556 316.1.1.13 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RelA_SpoT 0.50 43.0 3.90e-01 91.3% 84.3%
D4 medium residues 291-378
PDB
Domain cluster: rep: Rep_68_protein__YP_680422__adeno-associated_virus_2__10804__D219-282
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 41.9 8.80e-11 100.0% 31.4%