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nonstructural_protein_NS1
Euk-VirZika_virus
nonstructural_protein_NS1__YP_009227199__Zika_virus__64320
Identity
- Accession:
- YP_009227199 ↗
- Protein ID:
- nonstructural_protein_NS1
- Kingdom:
- euk
Quality
89.8
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Zika_virus
TaxID: 64320
Cluster
View cluster (33 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 28-171
Domain cluster:
rep: non-structural_protein_NS1__NP_775517__Powassan_virus__11083__D32-172
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00948.27 best | Flavi_NS1 | 174.7 | 3.80e-51 | 100.0% | 41.1% |
D2
medium
residues 175-279
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00948.27 best | Flavi_NS1 | 143.4 | 1.30e-41 | 100.0% | 29.2% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p6pA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.67 | 35.0 | 3.30e-01 | 98.1% | 42.4% |
| 1jqpA01 | 2.40.128.80 | Mainly Beta › Beta Barrel › Lipocalin › Cathepsin C, exclusion domain | 0.60 | 35.0 | 3.44e-01 | 97.1% | 54.5% |
| 3igfA02 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.59 | 30.0 | 3.54e-01 | 73.3% | 68.9% |
| 3vsmA03 | 2.60.40.4340 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.57 | 44.0 | 4.66e-01 | 93.3% | 92.6% |
| 3lxqA01 | 3.30.1120.80 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.55 | 34.0 | 3.49e-01 | 75.2% | 64.6% |
| 2jpiA00 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.55 | 36.0 | 3.79e-01 | 90.5% | 72.9% |
| 1hdhA02 | 3.30.1120.10 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.54 | 33.0 | 3.78e-01 | 72.4% | 83.1% |
| 2z1kA02 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.54 | 37.0 | 4.04e-01 | 82.9% | 88.2% |
| 2z0fA04 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.53 | 35.0 | 3.54e-01 | 73.3% | 67.6% |
| 2ovsA00 | 2.40.128.380 | Mainly Beta › Beta Barrel › Lipocalin › T3SS negative regulator GrlR | 0.53 | 39.0 | 3.77e-01 | 83.8% | 68.6% |
| 1f49A05 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.52 | 47.0 | 3.40e-01 | 99.0% | 86.2% |
| 3pgbA01 | 2.70.98.20 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain | 0.52 | 43.0 | 2.81e-01 | 91.4% | 77.8% |
| 1nkgA01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.51 | 45.0 | 3.41e-01 | 97.1% | 68.5% |
| 4ba0A01 | 2.60.40.1760 | Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) | 0.51 | 44.0 | 3.59e-01 | 95.2% | 99.5% |
| 6jwfA01 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.51 | 41.0 | 2.88e-01 | 90.5% | 58.0% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1282876 | 3829.1.1.1 ↗ | beta meanders › Flavivirus non-structural protein 1 (NS1) beta-meander domain › Flavivirus non-structural protein 1 (NS1) beta-meander domain › Flavivirus non-structural protein 1 (NS1) beta-meander domain › Flavi_NS1 | 0.98 | 95.0 | 7.49e-01 | 100.0% | 55.6% |
| 4875075 | 3828.1.1.1 ↗ | a/b three-layered sandwiches › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavi_NS1 | 0.98 | 89.0 | 7.26e-01 | 93.3% | 57.3% |
| 3971924 | 331.2.1.0 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain | 0.67 | 37.0 | 4.10e-01 | 72.4% | 67.9% |
| 4079675 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.62 | 30.0 | 3.00e-01 | 89.5% | 44.0% |
| 5000165 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.57 | 48.0 | 3.42e-01 | 92.4% | 89.8% |
| 3999577 | 4099.1.1.28 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › PF29108 | 0.57 | 38.0 | 4.20e-01 | 89.5% | 84.7% |
| 3585029 | 3735.1.1.14 ↗ | beta meanders › Rearrangement hotspot (RHS) repeats protein › Rearrangement hotspot (RHS) repeats protein › Rearrangement hotspot (RHS) repeats protein › TEN_YD-shell | 0.56 | 49.0 | 2.84e-01 | 95.2% | 28.8% |
| 3617987 | 4099.1.1.28 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › PF29108 | 0.56 | 38.0 | 4.23e-01 | 89.5% | 87.1% |
| 3628751 | 331.18.1.0 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc | 0.55 | 45.0 | 3.69e-01 | 87.6% | 68.6% |
| 3934099 | 4099.1.1.0 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like | 0.54 | 38.0 | 4.06e-01 | 89.5% | 83.3% |
| 3996119 | 5.1.4.417 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › KNTC1_N | 0.54 | 40.0 | 2.69e-01 | 76.2% | 88.1% |
| None | — | 0.53 | 38.0 | 2.52e-01 | 74.3% | 98.3% | |
| 3869277 | 331.18.1.0 ↗ | a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc | 0.53 | 43.0 | 3.56e-01 | 86.7% | 70.8% |
| 3957324 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.53 | 34.0 | 3.83e-01 | 93.3% | 85.0% |
| 3317337 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.53 | 37.0 | 2.49e-01 | 73.3% | 93.6% |
| 3590950 | 79.1.1.0 ↗ | beta duplicates or obligate multimers › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain | 0.52 | 35.0 | 3.05e-01 | 90.5% | 45.8% |
| 3797427 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.51 | 39.0 | 2.72e-01 | 81.0% | 99.4% |
| None | — | 0.51 | 40.0 | 2.55e-01 | 85.7% | 79.5% |
D3
medium
residues 280-350
Domain cluster:
rep: nonstructural_protein_NS1__YP_009163751__Spanish_goat_encephalitis_virus__1691889__D285-347
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00948.27 best | Flavi_NS1 | 123.7 | 1.10e-35 | 100.0% | 19.7% |