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nonstructural_protein_NS2B

Euk-Vir

Nakiwogo_virus

nonstructural_protein_NS2B__YP_009268607__Nakiwogo_virus__667516

Identity

Accession:
YP_009268607 ↗
Protein ID:
nonstructural_protein_NS2B
Kingdom:
euk

Quality

66.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 4-48_79-141
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 59.0 5.35e-01 92.6% 91.1%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.67 56.0 4.58e-01 90.7% 65.3%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 58.0 5.67e-01 93.5% 92.3%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 31.0 4.15e-01 76.9% 83.1%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.66 57.0 5.58e-01 94.4% 91.6%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 55.0 5.13e-01 93.5% 80.6%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.64 54.0 5.30e-01 91.7% 85.1%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.63 53.0 5.04e-01 90.7% 80.0%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 40.0 4.57e-01 77.8% 89.6%
4djhA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 52.0 3.83e-01 90.7% 84.3%
1hz4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 34.0 2.34e-01 74.1% 15.0%
4cmyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 44.0 3.83e-01 74.1% 81.6%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.61 49.0 5.03e-01 90.7% 90.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 50.0 4.94e-01 93.5% 91.6%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 36.0 4.18e-01 75.0% 86.5%
3kwoA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 45.0 4.02e-01 78.7% 94.0%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.59 50.0 4.93e-01 93.5% 86.3%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 50.0 4.83e-01 93.5% 91.7%
6ko5A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 51.0 3.79e-01 97.2% 80.1%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 49.0 4.78e-01 90.7% 87.3%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.58 50.0 4.76e-01 97.2% 80.5%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.57 51.0 4.62e-01 100.0% 75.5%
2pybA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 42.0 3.78e-01 77.8% 90.7%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 48.0 4.57e-01 91.7% 94.4%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.57 43.0 3.94e-01 97.2% 60.3%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.55 41.0 4.13e-01 77.8% 86.1%
4fymF00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 41.0 3.35e-01 83.3% 51.7%
3lpzA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 43.0 3.08e-01 86.1% 30.8%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 35.0 3.72e-01 75.0% 80.6%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 37.0 3.42e-01 76.9% 83.0%
5y9sC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 29.0 3.28e-01 88.0% 73.2%
3rkvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 39.0 3.53e-01 99.1% 60.5%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4032446 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.71 44.0 5.19e-01 74.1% 89.3%
3829175 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.70 34.0 3.33e-01 97.2% 42.5%
3407719 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.69 59.0 4.11e-01 93.5% 32.0%
3255556 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.67 58.0 4.23e-01 93.5% 37.9%
5078878 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.66 52.0 4.51e-01 83.3% 88.5%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 56.0 5.41e-01 93.5% 89.2%
3941436 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 55.0 5.23e-01 93.5% 87.2%
4257864 3281.1.1.1 alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M 0.63 56.0 3.69e-01 100.0% 61.7%
3249525 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 53.0 4.88e-01 93.5% 82.8%
3681194 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 46.0 4.42e-01 77.8% 73.6%
2758046 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.62 52.0 5.00e-01 93.5% 88.9%
3385577 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.62 53.0 4.98e-01 93.5% 86.9%
3249531 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 51.0 4.84e-01 90.7% 96.2%
3663661 604.12.1.90 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › NatA_aux_su 0.61 44.0 4.36e-01 75.0% 74.8%
3573786 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.61 52.0 4.25e-01 93.5% 55.0%
4018342 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 47.0 4.71e-01 93.5% 82.7%
4953902 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 53.0 3.54e-01 100.0% 91.3%
3883919 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.59 50.0 3.62e-01 93.5% 72.9%
None 0.59 52.0 3.75e-01 98.1% 78.1%
3974600 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.59 52.0 4.86e-01 96.3% 79.2%
5072045 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.59 42.0 4.25e-01 75.9% 75.2%
3673003 3922.1.1.254 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › NET2A_C 0.58 43.0 4.12e-01 77.8% 80.8%
3970726 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.58 52.0 4.79e-01 99.1% 93.6%
3920784 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 51.0 3.56e-01 100.0% 42.2%
3712551 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.56 47.0 3.71e-01 92.6% 46.0%
3211543 109.4.1.1839 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Otopetrin 0.55 49.0 3.86e-01 96.3% 94.5%
5061540 2498.1.1.147 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF7897 0.55 48.0 3.48e-01 99.1% 37.3%
3216054 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.55 48.0 3.57e-01 100.0% 84.0%
3236655 109.4.1.1839 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Otopetrin 0.55 48.0 3.85e-01 98.1% 92.7%
4998807 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 48.0 3.29e-01 100.0% 90.4%
3657338 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 37.0 4.08e-01 77.8% 90.6%
3222182 601.1.2.98 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Otopetrin 0.54 48.0 3.81e-01 97.2% 91.4%
3214666 109.3.1.358 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Otopetrin 0.54 48.0 3.80e-01 97.2% 94.4%
5063259 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.54 45.0 4.31e-01 91.7% 92.8%
3378335 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 37.0 3.85e-01 77.8% 81.1%
3565644 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 43.0 3.17e-01 91.7% 72.0%
3924515 3922.1.1.244 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Otopetrin 0.53 47.0 3.00e-01 96.3% 39.2%
2323994 604.37.1.0 alpha bundles › Spectrin repeat-like › Legionella effector Lem22 › Legionella effector Lem22 0.52 35.0 3.81e-01 76.9% 84.4%
5063260 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.51 42.0 4.21e-01 90.7% 94.5%
4957516 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.51 37.0 3.58e-01 76.9% 84.7%
4936574 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.51 38.0 3.46e-01 79.6% 78.0%