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nonstructural_protein_NS2B
Euk-VirHanko_virus
nonstructural_protein_NS2B__YP_009268623__Hanko_virus__1125677
Identity
- Accession:
- YP_009268623 ↗
- Protein ID:
- nonstructural_protein_NS2B
- Kingdom:
- euk
Quality
66.5
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Hanko_virus
TaxID: 1125677
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-55_76-94
D2
medium
residues 95-149
Domain cluster:
representative
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 63.0 | 6.22e-01 | 98.2% | 88.1% |
| 2xevB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.76 | 62.0 | 4.90e-01 | 96.4% | 44.4% |
| 2gw1A02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.74 | 60.0 | 3.67e-01 | 92.7% | 60.6% |
| 2b6cA01 | 1.20.1660.10 | Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) | 0.74 | 63.0 | 5.05e-01 | 100.0% | 81.0% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.73 | 59.0 | 4.98e-01 | 92.7% | 67.0% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.72 | 62.0 | 4.71e-01 | 100.0% | 45.7% |
| 3owaA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.71 | 57.0 | 4.37e-01 | 92.7% | 55.1% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 60.0 | 5.07e-01 | 98.2% | 83.5% |
| 2mhkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 62.0 | 4.78e-01 | 100.0% | 95.2% |
| 4gf0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.71 | 60.0 | 4.84e-01 | 98.2% | 77.9% |
| 3ph0C00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.71 | 57.0 | 5.85e-01 | 96.4% | 96.2% |
| 1ldjA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.71 | 60.0 | 4.74e-01 | 100.0% | 74.0% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.71 | 48.0 | 3.65e-01 | 70.9% | 70.6% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 53.0 | 4.17e-01 | 81.8% | 52.6% |
| 2vkjA00 | 1.20.58.2030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 60.0 | 4.90e-01 | 100.0% | 57.5% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.69 | 58.0 | 5.83e-01 | 96.4% | 100.0% |
| 2au3A04 | 1.20.50.30 | Mainly Alpha › Up-down Bundle › Pheromone ER-1 › | 0.68 | 49.0 | 4.96e-01 | 81.8% | 81.8% |
| 4a1nA02 | 6.10.250.1250 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 52.0 | 5.40e-01 | 90.9% | 94.0% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.67 | 46.0 | 4.18e-01 | 70.9% | 97.3% |
| 3kp9A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.67 | 46.0 | 3.32e-01 | 72.7% | 79.0% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 55.0 | 4.46e-01 | 98.2% | 76.5% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 44.0 | 4.24e-01 | 70.9% | 97.0% |
| 6u3wB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 55.0 | 3.58e-01 | 100.0% | 19.2% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.66 | 51.0 | 4.54e-01 | 87.3% | 78.3% |
| 4x28C01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.66 | 56.0 | 4.45e-01 | 100.0% | 63.0% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 55.0 | 4.27e-01 | 98.2% | 77.7% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 45.0 | 3.64e-01 | 72.7% | 44.5% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 45.0 | 4.12e-01 | 74.5% | 74.0% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.65 | 46.0 | 3.66e-01 | 74.5% | 85.1% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 44.0 | 3.83e-01 | 70.9% | 70.5% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 43.0 | 3.64e-01 | 70.9% | 43.9% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 52.0 | 4.19e-01 | 100.0% | 80.3% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 43.0 | 4.28e-01 | 72.7% | 83.1% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 44.0 | 4.30e-01 | 72.7% | 81.7% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 51.0 | 5.03e-01 | 94.5% | 88.5% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 54.0 | 4.10e-01 | 100.0% | 91.9% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 42.0 | 3.95e-01 | 76.4% | 57.4% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 49.0 | 4.39e-01 | 100.0% | 100.0% |
| 1oisA01 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.61 | 47.0 | 4.03e-01 | 85.5% | 63.0% |
| 4ewcA03 | 1.20.120.1660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 47.0 | 4.32e-01 | 89.1% | 62.7% |
| 2wvxA04 | 1.20.1610.10 | Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains | 0.61 | 49.0 | 3.43e-01 | 87.3% | 94.8% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 48.0 | 3.86e-01 | 89.1% | 71.4% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.59 | 41.0 | 3.66e-01 | 72.7% | 51.9% |
| 4nphA02 | 1.20.1270.330 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 43.0 | 3.89e-01 | 80.0% | 97.3% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 45.0 | 3.61e-01 | 96.4% | 78.1% |
| 1vquA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.57 | 42.0 | 4.03e-01 | 87.3% | 70.1% |
| 2dsjA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.56 | 48.0 | 4.55e-01 | 98.2% | 83.6% |
| 2dzlA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.52 | 40.0 | 3.82e-01 | 100.0% | 71.2% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3984493 | 325.1.7.28 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_YBHG | 0.73 | 51.0 | 3.82e-01 | 72.7% | 57.7% |
| 3370771 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 60.0 | 3.67e-01 | 100.0% | 23.3% |
| 3514718 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.71 | 58.0 | 4.67e-01 | 94.5% | 86.1% |
| 3704286 | 604.12.1.8 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT | 0.71 | 60.0 | 5.01e-01 | 98.2% | 67.0% |
| 4061849 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.70 | 49.0 | 3.85e-01 | 72.7% | 37.3% |
| 4810647 | 109.47.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical C-terminal domain in magnesium chelatase catalytic subunit › Helical C-terminal domain in magnesium chelatase catalytic subunit › CobN-Mg_chel | 0.70 | 59.0 | 5.29e-01 | 98.2% | 83.7% |
| 3906253 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.69 | 52.0 | 4.07e-01 | 83.6% | 37.5% |
| 3940815 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.69 | 59.0 | 4.65e-01 | 96.4% | 80.9% |
| 3423908 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.69 | 58.0 | 4.83e-01 | 92.7% | 90.5% |
| 4543996 | 3600.1.1.1 ↗ | alpha bundles › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › YlqD | 0.69 | 48.0 | 3.85e-01 | 72.7% | 39.0% |
| 4992256 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 56.0 | 4.80e-01 | 100.0% | 93.9% |
| 3392286 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.68 | 57.0 | 4.64e-01 | 98.2% | 100.0% |
| 3073109 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 47.0 | 4.27e-01 | 72.7% | 55.4% |
| 5082516 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.67 | 46.0 | 3.38e-01 | 72.7% | 27.3% |
| 3628598 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 55.0 | 5.05e-01 | 100.0% | 97.5% |
| 3390311 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.66 | 50.0 | 4.14e-01 | 87.3% | 92.7% |
| 3174278 | 5048.1.1.1 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP | 0.66 | 54.0 | 3.41e-01 | 96.4% | 35.1% |
| 3971026 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 45.0 | 3.52e-01 | 72.7% | 39.2% |
| 3969814 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.65 | 45.0 | 4.09e-01 | 70.9% | 82.7% |
| 4009031 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 46.0 | 3.98e-01 | 72.7% | 56.5% |
| 3945031 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.65 | 44.0 | 3.39e-01 | 70.9% | 97.7% |
| 3738569 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.65 | 49.0 | 4.17e-01 | 89.1% | 94.3% |
| 4957270 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 50.0 | 3.80e-01 | 85.5% | 74.1% |
| 4046042 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.63 | 44.0 | 3.45e-01 | 72.7% | 91.2% |
| 4362754 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.62 | 42.0 | 3.33e-01 | 70.9% | 54.2% |
| 3605626 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.62 | 54.0 | 4.42e-01 | 100.0% | 89.5% |
| None | — | 0.62 | 42.0 | 3.32e-01 | 72.7% | 54.6% | |
| 5083949 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.62 | 43.0 | 3.32e-01 | 72.7% | 50.8% |
| 3482273 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.62 | 50.0 | 4.22e-01 | 100.0% | 98.2% |
| 5055141 | 3896.1.2.1 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › CarS-like | 0.61 | 50.0 | 3.43e-01 | 90.9% | 58.0% |
| 3166260 | 1.1.7.123 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 | 0.61 | 43.0 | 3.31e-01 | 74.5% | 40.8% |
| 3974231 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.61 | 44.0 | 4.10e-01 | 76.4% | 95.7% |
| 3296525 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.60 | 50.0 | 3.74e-01 | 96.4% | 56.0% |
| 5047389 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.60 | 42.0 | 3.31e-01 | 94.5% | 33.1% |
| 4525341 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.59 | 41.0 | 3.84e-01 | 72.7% | 92.9% |
| 3947741 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.58 | 40.0 | 3.21e-01 | 76.4% | 34.2% |
| 3834594 | 601.27.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › MW0975(SA0943)-like › MW0975(SA0943)-like › DUF632, DUF630 | 0.57 | 45.0 | 3.44e-01 | 94.5% | 65.8% |