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nonstructural_protein_NS2B
Euk-VirCacipacore_virus
nonstructural_protein_NS2B__YP_009333110__Cacipacore_virus__64305
Identity
- Accession:
- YP_009333110 ↗
- Protein ID:
- nonstructural_protein_NS2B
- Kingdom:
- euk
Quality
70.6
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Cacipacore_virus
TaxID: 64305
Cluster
View cluster (16 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 76-132
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.83 | 61.0 | 4.71e-01 | 77.2% | 40.7% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.81 | 59.0 | 4.86e-01 | 77.2% | 48.0% |
| 1vf6C00 | 1.10.287.650 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain | 0.79 | 53.0 | 5.62e-01 | 70.2% | 82.4% |
| 1x0tA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.77 | 53.0 | 5.26e-01 | 71.9% | 73.8% |
| 1h72C02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.75 | 52.0 | 3.83e-01 | 71.9% | 32.6% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 54.0 | 5.25e-01 | 77.2% | 82.5% |
| 1kf6D00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.73 | 52.0 | 4.11e-01 | 75.4% | 49.6% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.73 | 51.0 | 5.21e-01 | 73.7% | 83.9% |
| 2y4tA02 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.73 | 51.0 | 5.28e-01 | 73.7% | 88.5% |
| 1vwxQ00 | 3.100.10.10 | Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › | 0.72 | 46.0 | 3.23e-01 | 71.9% | 19.8% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.71 | 53.0 | 4.87e-01 | 80.7% | 79.7% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 49.0 | 4.92e-01 | 71.9% | 75.9% |
| 2qkdA02 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.70 | 50.0 | 3.82e-01 | 77.2% | 57.1% |
| 8h6rA01 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.68 | 47.0 | 4.15e-01 | 71.9% | 49.4% |
| 3vw7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 49.0 | 3.12e-01 | 77.2% | 31.2% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.68 | 48.0 | 4.70e-01 | 75.4% | 75.0% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.67 | 46.0 | 4.67e-01 | 71.9% | 96.6% |
| 5svlA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.66 | 50.0 | 4.80e-01 | 86.0% | 92.6% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.66 | 49.0 | 4.43e-01 | 82.5% | 61.0% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.66 | 47.0 | 4.45e-01 | 75.4% | 63.4% |
| 3owaA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.66 | 51.0 | 3.93e-01 | 87.7% | 46.4% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.64 | 46.0 | 3.62e-01 | 77.2% | 35.7% |
| 2b9sA02 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.64 | 42.0 | 3.77e-01 | 70.2% | 47.1% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 44.0 | 4.15e-01 | 78.9% | 78.4% |
| 5ejrA01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.62 | 49.0 | 3.37e-01 | 87.7% | 47.3% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.59 | 42.0 | 3.62e-01 | 75.4% | 45.5% |
| 2kgfA00 | 1.10.375.10 | Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein | 0.59 | 41.0 | 3.20e-01 | 75.4% | 74.3% |
| 3ckcA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 49.0 | 3.55e-01 | 96.5% | 53.7% |
| 1a59A02 | 1.10.230.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 | 0.59 | 41.0 | 3.44e-01 | 75.4% | 39.8% |
| 5unhA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 52.0 | 3.31e-01 | 100.0% | 34.9% |
| 3cqyB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 44.0 | 3.22e-01 | 100.0% | 57.1% |
| 2b9wA02 | 1.10.405.20 | Mainly Alpha › Orthogonal Bundle › Guanine Nucleotide Dissociation Inhibitor; domain 1 › | 0.52 | 38.0 | 3.24e-01 | 87.7% | 57.6% |
| 2lo0A00 | 1.10.286.70 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › Get5 dimerization domain | 0.51 | 38.0 | 4.17e-01 | 82.5% | 100.0% |
| 2damA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.51 | 33.0 | 3.15e-01 | 73.7% | 56.7% |
| 2q74A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.50 | 39.0 | 3.16e-01 | 100.0% | 41.1% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5043972 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.78 | 53.0 | 4.40e-01 | 70.2% | 44.4% |
| 3749999 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.78 | 52.0 | 4.49e-01 | 70.2% | 44.4% |
| 4943339 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.77 | 53.0 | 4.34e-01 | 71.9% | 45.0% |
| 3376654 | 3289.1.1.0 ↗ | alpha complex topology › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 | 0.75 | 54.0 | 2.90e-01 | 77.2% | 4.2% |
| 3899139 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.74 | 51.0 | 3.21e-01 | 73.7% | 26.6% |
| 5001301 | 3636.1.1.0 ↗ | a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain | 0.73 | 49.0 | 3.70e-01 | 70.2% | 44.4% |
| 4954895 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.72 | 50.0 | 4.30e-01 | 71.9% | 45.6% |
| 5018020 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 50.0 | 5.28e-01 | 75.4% | 100.0% |
| 3987696 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 47.0 | 3.40e-01 | 73.7% | 29.1% |
| 3631425 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.65 | 58.0 | 4.10e-01 | 98.2% | 63.0% |
| 5050929 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.65 | 58.0 | 5.29e-01 | 100.0% | 96.0% |
| 4927432 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.65 | 55.0 | 4.96e-01 | 96.5% | 70.0% |
| 3208859 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.64 | 56.0 | 4.04e-01 | 98.2% | 63.6% |
| 3540156 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.64 | 54.0 | 3.43e-01 | 98.2% | 56.8% |
| 2073547 | 621.1.1.2 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Smg8_Smg9 | 0.63 | 46.0 | 4.45e-01 | 96.5% | 69.2% |
| 5006770 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.63 | 44.0 | 3.23e-01 | 73.7% | 28.1% |
| 3932745 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.63 | 53.0 | 3.43e-01 | 100.0% | 75.6% |
| 3679686 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.62 | 51.0 | 3.56e-01 | 100.0% | 92.4% |
| 3356095 | 601.37.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Photosystem II lipoprotein Psb27 › Photosystem II lipoprotein Psb27 › PSII_Pbs27 | 0.62 | 52.0 | 4.18e-01 | 98.2% | 97.5% |
| 4191800 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.61 | 37.0 | 3.84e-01 | 70.2% | 63.6% |
| 2755218 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.61 | 48.0 | 3.45e-01 | 94.7% | 60.2% |
| 3213226 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.61 | 41.0 | 3.99e-01 | 71.9% | 98.5% |
| 3877843 | 3075.1.1.2 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › UPF0561 | 0.61 | 41.0 | 3.96e-01 | 70.2% | 98.4% |
| 3731212 | 192.24.1.0 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain | 0.58 | 39.0 | 3.56e-01 | 70.2% | 62.4% |
| 4011414 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.57 | 46.0 | 3.28e-01 | 100.0% | 60.5% |
| 3248675 | 568.1.1.0 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related | 0.57 | 39.0 | 3.70e-01 | 98.2% | 57.3% |
| 3620852 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.57 | 38.0 | 3.90e-01 | 70.2% | 100.0% |
| 3857154 | 101.1.2.151 ↗ | alpha arrays › HTH › HTH › winged helix domain › COR | 0.54 | 44.0 | 3.56e-01 | 93.0% | 53.3% |
| 3711095 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.54 | 44.0 | 4.08e-01 | 93.0% | 98.7% |
| 5056488 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.53 | 44.0 | 3.05e-01 | 94.7% | 69.0% |
| 3731940 | 633.23.1.12 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Fig1 | 0.53 | 42.0 | 2.89e-01 | 96.5% | 62.4% |
| 3725284 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 39.0 | 3.34e-01 | 82.5% | 50.5% |
| 184798 | 3443.1.1.1 ↗ | alpha duplicates or obligate multimers › Get5 carboxyl domain › Get5 carboxyl domain › Get5 carboxyl domain › Get5_C | 0.51 | 38.0 | 4.17e-01 | 82.5% | 100.0% |