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nonstructural_protein_NS3

Euk-Vir

Lammi_virus

nonstructural_protein_NS3__YP_009268592__Lammi_virus__649187

Identity

Accession:: YP_009268592 ↗
Protein ID:: nonstructural_protein_NS3
Kingdom:: euk

Quality

81.9 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Lammi_virus

TaxID: 649187

Cluster

View cluster (28 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 335-476

PDB

Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00271.38 best	Helicase_C	25.4	2.00e-05	83.8%	85.5%

D2 medium residues 18-163

PDB

Domain cluster: rep: 100_kDa_protein__YP_008130303__Citrus_vein_enation_virus__1301220__D379-571

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00949.28 best	Peptidase_S7	102.1	3.10e-29	100.0%	90.8%
PF02907.22	Peptidase_S29	30.1	5.20e-07	93.2%	79.9%

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2wv9A01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.96	93.0	8.64e-01	100.0%	84.3%
4m9fA00	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.93	90.0	7.87e-01	100.0%	72.5%
2ok5A02	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.77	64.0	5.52e-01	87.0%	100.0%
4b6eB01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.77	69.0	6.10e-01	100.0%	68.3%
1lvoA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.76	40.0	5.06e-01	98.6%	84.1%
2ijd101	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.74	69.0	6.37e-01	99.3%	87.8%
1lvbA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.73	42.0	4.89e-01	98.6%	77.8%
2o8mB01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.72	33.0	4.97e-01	88.4%	98.5%
3su0A01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.72	34.0	3.86e-01	89.0%	58.9%
3l6pA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.69	46.0	5.46e-01	97.9%	93.3%
2rceA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.69	41.0	4.77e-01	83.6%	81.1%
1hpgA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.58	37.0	4.43e-01	98.6%	94.9%
1boqA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.54	37.0	4.28e-01	98.6%	96.3%
4ic6C01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.54	34.0	3.89e-01	88.4%	84.5%
2gk6A02	2.40.30.230	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 ›	0.50	29.0	3.71e-01	71.9%	98.8%
5mj6A03	2.60.40.1910	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.50	27.0	3.51e-01	70.5%	93.8%

ECOD (26)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
169988	1.1.5.6 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S7	0.98	95.0	8.82e-01	100.0%	83.8%
None	—		0.97	94.0	8.92e-01	100.0%	87.3%
1311889	1.1.5.7 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel	0.79	74.0	6.15e-01	100.0%	60.4%
5063379	1.1.17.3 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2	0.79	74.0	6.85e-01	99.3%	88.3%
3963124	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.79	73.0	6.34e-01	98.6%	82.8%
3439936	1.1.17.3 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2	0.78	73.0	5.73e-01	98.6%	90.5%
3611892	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.78	73.0	6.61e-01	98.6%	83.2%
4329871	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.78	72.0	6.54e-01	98.6%	84.2%
3601993	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.77	72.0	6.44e-01	98.6%	81.0%
140973	1.1.17.3 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2	0.77	71.0	6.07e-01	98.6%	74.0%
3719164	1.1.5.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel	0.77	72.0	6.53e-01	99.3%	83.2%
3989070	1.1.17.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin	0.77	71.0	6.15e-01	98.6%	86.2%
1161323	1.1.5.14 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S29	0.77	69.0	6.37e-01	100.0%	76.2%
None	—		0.77	72.0	6.22e-01	99.3%	82.8%
5039728	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.77	71.0	5.97e-01	100.0%	89.6%
None	—		0.76	72.0	6.21e-01	99.3%	82.6%
3401129	1.1.17.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin	0.74	69.0	5.82e-01	99.3%	86.4%
4247805	1.1.5.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin	0.73	69.0	5.97e-01	99.3%	80.6%
4822902	1.1.17.3 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2	0.73	65.0	6.33e-01	93.8%	91.1%
4387060	1.1.17.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin	0.73	68.0	5.91e-01	99.3%	81.4%
None	—		0.73	68.0	5.95e-01	99.3%	83.3%
3397694	1.1.17.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin	0.70	65.0	5.47e-01	99.3%	80.9%
3615787	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.70	65.0	5.56e-01	99.3%	79.1%
4974463	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.70	66.0	6.31e-01	100.0%	90.2%
4092486	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.61	55.0	5.16e-01	99.3%	83.3%
4960051	1.1.5.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel	0.59	53.0	5.06e-01	100.0%	91.4%

D3 medium residues 164-183_200-234

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07652.21 best	Flavi_DEAD	50.9	2.40e-13	87.3%	30.4%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3b8xA02	3.90.1150.10	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1	0.54	37.0	2.87e-01	72.7%	62.1%
4zxwB01	3.30.559.10	Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain	0.50	39.0	2.84e-01	89.1%	49.4%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3983802	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	46.0	3.95e-01	76.4%	68.9%
3590570	101.1.2.368 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_36	0.54	38.0	2.97e-01	76.4%	88.0%

D4 medium residues 184-199_235-326

PDB

Domain cluster: rep: LD_Run2_08_scaffold_35_prodigal-single.1__X__X__00177__D121-323

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07652.21 best	Flavi_DEAD	138.0	3.30e-40	86.1%	61.5%

D5 medium residues 519-618

PDB

Domain cluster: rep: non-structural_protein_NS3__NP_776005__Yellow_fever_virus__11089__D541-620

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF20907.3 best	Flav_NS3-hel_C	99.7	1.80e-28	99.0%	66.7%