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nonstructural_protein_NS3

Euk-Vir

Zika_virus

nonstructural_protein_NS3__YP_009430304__Zika_virus__64320

Identity

Accession:
YP_009430304 ↗
Protein ID:
nonstructural_protein_NS3
Kingdom:
euk

Quality

88.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 21-166
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00949.28 best Peptidase_S7 100.8 7.60e-29 100.0% 93.1%
PF02907.22 Peptidase_S29 28.9 1.20e-06 96.6% 87.2%
D2 high residues 181-322
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00270.36 best DEAD 30.5 3.90e-07 100.0% 88.0%
PF07652.21 Flavi_DEAD 238.0 5.10e-71 97.9% 93.2%
D3 high residues 333-473
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00271.38 best Helicase_C 27.6 4.10e-06 82.3% 87.3%
D4 medium residues 509-614
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20907.3 best Flav_NS3-hel_C 185.9 4.80e-55 100.0% 73.6%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2damA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.63 39.0 4.68e-01 100.0% 97.0%
1oaiA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.63 36.0 4.44e-01 75.5% 98.3%
2jp7A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.62 35.0 4.36e-01 81.1% 100.0%
1rykA00 1.10.1470.10 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › YjbJ 0.62 33.0 3.94e-01 85.8% 78.3%
2vxdA00 1.10.10.2100 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nucleophosmin, C-terminal domain 0.56 29.0 3.79e-01 74.5% 94.4%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
53546 5101.1.1.0 alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase 0.98 96.0 8.61e-01 100.0% 77.9%
286894 5101.1.1.1 alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.96 93.0 8.13e-01 100.0% 72.8%
4878071 5101.1.1.1 alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › Flav_NS3-hel_C 0.95 92.0 8.06e-01 100.0% 73.3%
5068885 102.1.1.11 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › RNA_pol_Rpb4 0.70 36.0 3.96e-01 84.9% 58.9%
5031174 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.63 33.0 3.92e-01 86.8% 74.3%
5051504 103.2.1.0 alpha arrays › RuvA-C › ATP cone › ATP cone 0.59 35.0 4.09e-01 83.0% 82.7%
4930784 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.58 29.0 3.96e-01 85.8% 100.0%
3955867 148.1.3.251 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF30647 0.54 34.0 3.96e-01 83.0% 94.3%
4090171 2004.1.1.424 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase, AAA_2, AAA_5 0.51 36.0 2.69e-01 73.6% 94.8%