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nonstructural_protein_NS4A

Euk-Vir

Hepacivirus_M

nonstructural_protein_NS4A__YP_009664169__Hepacivirus_M__2008772

Identity

Accession:: YP_009664169 ↗
Protein ID:: nonstructural_protein_NS4A
Kingdom:: euk

Quality

71.6 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Hepacivirus› Hepacivirus_otomopis

TaxID: 2008772

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-54

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01006.26 best	HCV_NS4a	46.6	2.90e-12	100.0%	98.2%

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3u4qA02	1.10.274.50	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 ›	0.66	52.0	3.75e-01	85.2%	88.7%
4ywhA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.66	46.0	3.36e-01	74.1%	28.3%
7tjbA01	3.40.50.1110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase	0.64	44.0	3.03e-01	74.1%	50.5%
3r4iA02	6.10.140.960	Special › Helix non-globular › Helix Hairpins ›	0.61	36.0	3.55e-01	96.3%	53.3%
2r8rA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	39.0	2.63e-01	70.4%	45.9%
3dzzA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.56	45.0	2.91e-01	88.9%	30.7%
3b1dA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.56	45.0	2.96e-01	88.9%	33.3%
2gsdA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.55	44.0	2.94e-01	94.4%	22.7%
7xb6B01	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.55	42.0	2.91e-01	83.3%	30.8%
2ch0A01	1.10.10.1180	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MAN1, winged-helix domain	0.54	41.0	3.41e-01	83.3%	79.6%
5z0qA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.53	43.0	2.86e-01	88.9%	34.2%
3v33B00	3.40.50.11980	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	37.0	2.79e-01	79.6%	58.1%
3bjoA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	44.0	3.56e-01	96.3%	91.3%
4hv0C00	1.10.1220.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like	0.50	37.0	3.20e-01	81.5%	62.9%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5072747	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.64	41.0	4.01e-01	72.2%	60.0%
3487970	2006.1.4.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like	0.59	41.0	2.99e-01	74.1%	46.5%
5038778	5054.1.1.6 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH	0.58	40.0	3.03e-01	74.1%	31.9%
3348687	109.4.1.1156 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › E_motif	0.58	46.0	3.48e-01	87.0%	60.0%
3521947	2006.1.4.9 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › RNase_Zc3h12a	0.56	37.0	2.69e-01	70.4%	90.8%
3482328	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.52	42.0	3.38e-01	96.3%	45.7%
3686933	331.3.1.0 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like	0.50	42.0	3.06e-01	100.0%	40.6%