Back to structures

nonstructural_protein_NS4B

Euk-Vir

Nakiwogo_virus

nonstructural_protein_NS4B__YP_009268611__Nakiwogo_virus__667516

Identity

Accession:
YP_009268611 ↗
Protein ID:
nonstructural_protein_NS4B
Kingdom:
euk

Quality

71.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 47-163
PDB
D2 medium residues 164-242
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.75 58.0 5.37e-01 82.3% 71.0%
1td6A01 1.20.1480.10 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 0.74 54.0 4.93e-01 83.5% 58.8%
6umqA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.74 53.0 4.69e-01 75.9% 93.9%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 56.0 3.95e-01 84.8% 84.1%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 55.0 4.83e-01 83.5% 64.2%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 49.0 4.54e-01 72.2% 63.0%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.70 52.0 5.04e-01 78.5% 85.1%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.69 51.0 4.83e-01 78.5% 81.1%
3p42A02 6.10.250.2280 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 41.0 4.38e-01 82.3% 67.1%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.66 52.0 4.69e-01 86.1% 87.4%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 48.0 4.28e-01 82.3% 84.5%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 48.0 4.76e-01 82.3% 85.5%
3rlfF01 1.20.58.370 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like 0.63 47.0 4.62e-01 82.3% 79.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.62 47.0 4.17e-01 82.3% 58.1%
1lq7A00 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.61 46.0 4.94e-01 83.5% 98.5%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.60 46.0 4.31e-01 86.1% 84.3%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.60 47.0 4.30e-01 86.1% 73.3%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.58 39.0 3.65e-01 100.0% 52.4%
1hy0A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.58 44.0 3.75e-01 82.3% 53.3%
1op1A00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.58 42.0 4.22e-01 78.5% 86.6%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.57 48.0 4.89e-01 100.0% 97.4%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.56 41.0 3.65e-01 100.0% 50.8%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.56 44.0 4.42e-01 87.3% 96.3%
1cpyA02 1.10.287.410 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 40.0 4.20e-01 79.7% 100.0%
2vm6A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 43.0 3.53e-01 83.5% 79.2%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.54 40.0 3.16e-01 100.0% 34.8%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4966172 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.77 60.0 4.14e-01 83.5% 30.0%
4613294 4177.1.1.22 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › LXG 0.74 59.0 4.31e-01 84.8% 78.0%
3229912 633.21.1.4 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P 0.74 57.0 4.97e-01 82.3% 70.0%
3906133 633.21.1.4 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P 0.74 57.0 5.00e-01 82.3% 73.0%
5032752 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.73 58.0 5.67e-01 84.8% 95.3%
3719985 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.72 57.0 5.24e-01 86.1% 64.8%
3464325 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.72 55.0 5.42e-01 82.3% 97.6%
3737705 605.4.1.4 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 0.72 56.0 5.24e-01 84.8% 89.0%
4981575 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.71 55.0 4.64e-01 84.8% 60.7%
4964440 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.70 62.0 4.69e-01 100.0% 64.1%
4957637 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 56.0 5.36e-01 86.1% 83.3%
4982132 5069.1.3.135 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF5985 0.69 54.0 5.09e-01 83.5% 81.9%
3221100 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 54.0 4.69e-01 86.1% 65.6%
4032540 5069.1.3.10 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I 0.69 49.0 4.34e-01 73.4% 85.5%
3242356 605.4.1.19 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF30187 0.68 51.0 4.97e-01 81.0% 85.6%
4073103 4952.1.1.1 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1 0.68 51.0 4.50e-01 79.7% 63.5%
4114241 4952.1.1.0 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like 0.68 51.0 4.73e-01 79.7% 73.0%
3473655 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.68 53.0 3.46e-01 86.1% 29.3%
3603132 633.12.1.0 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.67 51.0 5.08e-01 83.5% 80.0%
3865887 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.67 51.0 5.05e-01 82.3% 85.9%
3891868 5086.1.1.21 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CARMIL_C 0.66 48.0 3.60e-01 77.2% 84.0%
3750409 186.1.1.24 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › PF31020 0.66 53.0 4.78e-01 86.1% 78.1%
4457905 4952.1.1.0 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like 0.65 49.0 4.53e-01 79.7% 73.0%
3521510 192.7.1.73 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › PF31020 0.65 52.0 4.66e-01 86.1% 74.5%
4952624 3843.1.1.29 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2105 0.65 51.0 4.97e-01 82.3% 84.7%
3673192 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 49.0 3.86e-01 82.3% 53.5%
4970978 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.65 57.0 5.22e-01 100.0% 86.7%
3890537 109.4.1.583 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi 0.64 54.0 4.43e-01 96.2% 49.3%
3836366 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.64 49.0 3.96e-01 84.8% 55.2%
3879800 601.3.1.8 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › IQUB 0.64 53.0 4.32e-01 88.6% 52.9%
3593935 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.64 50.0 4.25e-01 86.1% 50.4%
3435434 632.1.1.13 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N 0.64 49.0 4.55e-01 84.8% 82.9%
5079638 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.63 48.0 4.50e-01 82.3% 80.0%
3743598 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.63 53.0 4.50e-01 91.1% 65.6%
4993195 632.6.1.15 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › PF26119 0.63 45.0 4.23e-01 74.7% 82.1%
3481136 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 56.0 3.82e-01 100.0% 53.6%
3182665 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.62 46.0 4.37e-01 79.7% 81.1%
3697925 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.62 46.0 3.70e-01 79.7% 76.9%
3924462 632.1.1.11 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › HYOU1_C 0.62 47.0 4.14e-01 82.3% 70.0%
3784429 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.61 54.0 4.93e-01 100.0% 100.0%
4240705 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.60 45.0 4.41e-01 82.3% 88.2%
4927816 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 49.0 3.75e-01 100.0% 98.1%
4417066 174.1.1.78 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2127 0.57 52.0 4.22e-01 100.0% 55.2%
3424617 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.56 48.0 4.02e-01 96.2% 94.8%
3651085 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.55 48.0 3.25e-01 98.7% 71.0%
1203190 192.3.1.1 alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.52 39.0 3.72e-01 82.3% 97.8%
3457593 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.50 41.0 3.87e-01 93.7% 90.0%