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nonstructural_protein_NS4B

Euk-Vir

Hepacivirus_I

nonstructural_protein_NS4B__YP_009679031__Hepacivirus_I__2008768

Identity

Accession:
YP_009679031 ↗
Protein ID:
nonstructural_protein_NS4B
Kingdom:
euk

Quality

67.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-122
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01001.25 best HCV_NS4b 55.2 1.00e-14 87.8% 44.3%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1sz9C00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 44.0 4.13e-01 70.4% 55.0%
4gpkF02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 52.0 4.06e-01 88.7% 53.8%
3ubcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 39.0 3.75e-01 70.4% 66.4%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 43.0 3.62e-01 85.2% 79.0%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 38.0 3.53e-01 73.9% 65.7%
1cg5B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 37.0 3.46e-01 73.9% 66.0%
2yskA00 1.10.490.110 Mainly Alpha › Orthogonal Bundle › Globin-like › Uncharacterized conserved protein DUF2267 0.50 37.0 3.45e-01 77.4% 98.6%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5046289 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.70 49.0 4.72e-01 72.2% 91.5%
5010817 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 47.0 4.06e-01 70.4% 75.6%
3824988 109.3.1.339 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Vps35 0.63 44.0 3.83e-01 70.4% 50.9%
3592085 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.63 50.0 3.88e-01 86.1% 58.8%
3703139 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 49.0 3.87e-01 93.9% 69.2%
4544657 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 46.0 4.04e-01 84.3% 77.6%
3232833 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 41.0 3.05e-01 78.3% 77.3%
5026442 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.55 40.0 3.46e-01 74.8% 95.6%
3712847 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 40.0 3.31e-01 76.5% 85.6%
3623181 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.52 37.0 3.29e-01 73.0% 64.8%
51101 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.52 36.0 3.37e-01 70.4% 71.1%
3516155 109.4.1.414 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS19_N 0.51 42.0 3.17e-01 91.3% 45.8%
4927417 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.50 43.0 3.45e-01 95.7% 77.5%
D2 high residues 126-201_217-244
PDB