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nonstructural_protein_P1

Euk-Vir

Onyong-nyong_virus

nonstructural_protein_P1__NP_740703__Onyong-nyong_virus__2169701

Identity

Accession:
NP_740703 ↗
Protein ID:
nonstructural_protein_P1
Kingdom:
euk

Quality

71.4 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Togaviridae› Alphavirus› Onyong-nyong_virus

TaxID: 2169701

Cluster

View cluster (15 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 3-151
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 73.1 2.90e-20 95.3% 35.0%
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qdjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 48.0 4.25e-01 80.5% 50.5%
4qttB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 44.0 4.13e-01 79.2% 54.9%
1j6uA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.63 38.0 4.08e-01 75.8% 68.2%
1nv8A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 45.0 4.08e-01 98.0% 56.3%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 28.0 3.79e-01 83.9% 86.7%
3h5oA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 31.0 3.38e-01 71.8% 59.1%
1fcdA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.59 43.0 4.51e-01 75.8% 90.6%
3hm2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 43.0 4.11e-01 77.2% 70.2%
3fzgA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.03e-01 81.9% 68.4%
5fcdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 42.0 3.70e-01 78.5% 55.3%
2uyoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 49.0 4.05e-01 98.7% 65.8%
3frhA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 43.0 4.02e-01 81.9% 71.0%
2esrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 38.0 3.79e-01 72.5% 75.6%
2gs9A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 41.0 3.72e-01 98.0% 58.9%
3mmzC00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.54 30.0 2.96e-01 72.5% 47.5%
4fleA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 38.0 3.49e-01 73.2% 76.9%
2i5qA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.52 38.0 3.31e-01 76.5% 65.1%
1mv8A03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 3.80e-01 98.0% 63.9%
3ibtA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 41.0 3.80e-01 85.2% 95.9%
3clmA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 42.0 3.17e-01 87.2% 76.1%
4go1A02 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 43.0 3.66e-01 91.3% 84.0%
3cobC00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.51 38.0 2.94e-01 78.5% 67.9%
3daoB01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.50 32.0 3.17e-01 77.2% 59.2%
3bkxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 45.0 3.72e-01 100.0% 82.1%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4990381 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.66 40.0 4.06e-01 78.5% 60.7%
3950481 2003.1.5.21 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS 0.66 48.0 3.82e-01 98.0% 38.2%
3643218 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.65 47.0 3.69e-01 98.0% 37.0%
3329445 2003.1.5.21 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS 0.64 47.0 3.67e-01 97.3% 37.0%
4021707 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.62 45.0 3.76e-01 78.5% 43.5%
4126665 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.62 44.0 3.33e-01 97.3% 30.3%
5040508 2003.1.5.55 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA 0.61 45.0 4.14e-01 100.0% 59.5%
None — 0.61 48.0 4.50e-01 98.0% 67.6%
3720666 2003.1.5.335 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_23, Methyltransf_25 0.60 51.0 3.92e-01 92.6% 40.9%
3685527 2003.1.5.21 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS 0.57 49.0 3.69e-01 91.9% 43.4%
4132035 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.56 48.0 3.57e-01 94.6% 73.1%
4052441 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.56 48.0 3.61e-01 94.6% 79.5%
4989544 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.55 40.0 3.56e-01 77.2% 52.4%
4612674 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.55 48.0 3.58e-01 96.0% 78.1%
None — 0.55 48.0 3.58e-01 94.6% 78.1%
4655780 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.55 48.0 3.54e-01 94.6% 77.1%
5073115 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.54 41.0 3.77e-01 80.5% 69.3%
4134005 2003.1.5.156 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31 0.53 45.0 3.39e-01 93.3% 85.5%
4058341 7071.1.1.0 ↗ 0.53 38.0 2.97e-01 73.8% 46.1%
3241616 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.52 39.0 3.14e-01 81.2% 40.7%
5001639 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 40.0 3.48e-01 80.5% 77.3%
3278964 2006.1.1.11 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.52 33.0 3.38e-01 77.2% 63.3%
3510741 2003.1.5.156 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31 0.52 45.0 3.43e-01 98.0% 73.8%
4989338 2007.1.14.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.52 36.0 3.46e-01 85.2% 62.4%
4076202 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.52 46.0 3.42e-01 98.0% 72.2%
4673340 2003.1.5.174 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_15 0.52 45.0 3.44e-01 98.0% 75.2%
D2 medium residues 179-191_254-306_434-476
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5hexA01 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.58 41.0 3.06e-01 73.4% 80.9%
4qs8A01 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.56 40.0 3.01e-01 74.3% 81.8%
1bdgA01 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.54 38.0 2.92e-01 74.3% 81.0%
4zfvB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 37.0 3.11e-01 73.4% 96.3%
3hz6A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 39.0 3.02e-01 79.8% 75.7%
6p4xA03 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.52 42.0 3.17e-01 89.9% 93.3%
3ll3B02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 38.0 2.97e-01 78.9% 73.5%
2dpnA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 37.0 2.93e-01 78.9% 76.2%
2w40A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 37.0 2.90e-01 78.9% 76.5%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3259116 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.56 22.0 2.72e-01 82.6% 54.3%
D3 medium residues 192-218_230-253_307-337
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vwoA02 2.10.70.40 Mainly Beta › Ribbon › Complement Module; domain 1 › peptidoglycan hydrolase 0.67 29.0 3.66e-01 96.3% 66.7%
4aghA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.59 24.0 2.46e-01 72.0% 35.0%
4a17E01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.57 30.0 2.99e-01 96.3% 48.2%
6epkA02 3.30.67.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 0.55 34.0 3.68e-01 96.3% 73.2%
3p54A02 3.30.67.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 0.54 34.0 3.65e-01 96.3% 73.2%
1okeB02 3.30.67.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 0.51 34.0 3.52e-01 97.6% 71.4%
D4 medium residues 338-406
PDB